PE20010239A1 - Gen derivado de lawsonia y polipeptidos, peptidos y proteinas de hemolisina relacionados y sus usos - Google Patents
Gen derivado de lawsonia y polipeptidos, peptidos y proteinas de hemolisina relacionados y sus usosInfo
- Publication number
- PE20010239A1 PE20010239A1 PE2000000447A PE0004472000A PE20010239A1 PE 20010239 A1 PE20010239 A1 PE 20010239A1 PE 2000000447 A PE2000000447 A PE 2000000447A PE 0004472000 A PE0004472000 A PE 0004472000A PE 20010239 A1 PE20010239 A1 PE 20010239A1
- Authority
- PE
- Peru
- Prior art keywords
- sequence
- polypeptide
- amino acids
- hemolysin
- peptide
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 11
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 8
- 229920001184 polypeptide Polymers 0.000 title abstract 7
- 108010006464 Hemolysin Proteins Proteins 0.000 title abstract 3
- 241001469654 Lawsonia <weevil> Species 0.000 title abstract 3
- 239000003228 hemolysin Substances 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 5
- 241001148567 Lawsonia intracellularis Species 0.000 abstract 2
- 102000015636 Oligopeptides Human genes 0.000 abstract 2
- 108010038807 Oligopeptides Proteins 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 2
- 239000002773 nucleotide Substances 0.000 abstract 2
- 229960005486 vaccine Drugs 0.000 abstract 2
- 108020004414 DNA Proteins 0.000 abstract 1
- 102000053602 DNA Human genes 0.000 abstract 1
- 108010062010 N-Acetylmuramoyl-L-alanine Amidase Proteins 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 230000004727 humoral immunity Effects 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 239000013612 plasmid Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Abstract
SE REFIERE A UN POLIPEPTIDO INMUNOGENICO RECOMBINANTE O AISLADO QUE REACCIONA EN FORMA CRUZADA CON UN EPITOPE DE CELULA B O CELULA T DE UN POLIPEPTIDO DE HEMOLISINA DE LAWSONIA SPP DE PREFERENCIA L. INTRACELLULARIS, CAPAZ DE PRODUCIR LA PRODUCCION DE ANTICUERPOS, CONFERIR UNA RESPUESTA INMUNE PROTECTORA; INDUCIR INMUNIDAD HUMORAL; SE SELECCIONA DE a)UN PEPTIDO, OLIGOPEPTIDO, POLIPEPTIDO QUE COMPRENDE UNA SECUENCIA DE AMINOACIDOS CON 70% DE IDENTIDAD DE LA SECUENCIA SEC ID NO:1 DE 251 AMINOACIDOS O LA SECUENCIA DE AMINOACIDOS CODIFICADA POR LA SECUENCIA DE NUCLEOTIDOS QUE CODIFICA A LA HEMOLISINA DE pALK12(ATCC 207195); b)UN PEPTIDO, OLIGOPEPTIDO, POLIPEPTIDO QUE COMPRENDE UNA SECUENCIA DE AMINOACIDOS QUE TIENE POR LO MENOS 50% DE IDENTIDAD DE LA SECUENCIA CON LOS AMINOACIDOS 1 A 50 DE LA SECUENCIA SEC ID NO:1; c)UN HOMOLOGO, ANALOGO, DERIVADO QUE IMITA A UN EPITOPE DE CELULAS B O CELULAS T DE UN POLIPEPTIDO DE HEMOLISINA DE LAWSONIA SPP. SE REFIERE TAMBIEN A VACUNAS QUE COMPRENDEN ADEMAS UN SEGUNDO COMPONENTE QUE COMPRENDE UN PEPTIDO, POLIPEPTIDO O PROTEINA DE L.INTRACELLULARIS ANTIGENO TAL COMO SodC, OmpH, FlgE, AUTOLISINA; TAMBIEN SE REFIERE A UN VECTOR PARA VACUNAS, UNA MOLECULA DE ADN; UN PLASMIDO DESIGNADO pALK12
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13402299P | 1999-05-13 | 1999-05-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20010239A1 true PE20010239A1 (es) | 2001-02-28 |
Family
ID=22461415
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2000000447A PE20010239A1 (es) | 1999-05-13 | 2000-05-12 | Gen derivado de lawsonia y polipeptidos, peptidos y proteinas de hemolisina relacionados y sus usos |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1177213A4 (es) |
| AU (2) | AU775323B2 (es) |
| CA (1) | CA2372105A1 (es) |
| NZ (1) | NZ515363A (es) |
| PE (1) | PE20010239A1 (es) |
| WO (1) | WO2000069906A1 (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6605696B1 (en) | 1999-10-22 | 2003-08-12 | Pfizer, Inc. | Lawsonia intracellularis proteins, and related methods and materials |
| ATE330013T1 (de) | 2000-12-20 | 2006-07-15 | Intervet Int Bv | Lawsonia intracellularis impfstoff |
| US8834891B2 (en) | 2005-03-14 | 2014-09-16 | Boehringer Ingelheim Vetmedica, Inc. | Immunogenic compositions comprising Lawsonia intracellularis |
| US8398994B2 (en) | 2005-07-15 | 2013-03-19 | Boehringer Ingelheim Vetmedica, Inc. | Lawsonia vaccine and methods of use thereof |
| US20100129397A1 (en) | 2006-12-11 | 2010-05-27 | Boehringer Ingelheim Vetmedica, Inc. | Effective method of treatment of porcine circovirus and lawsonia intracellularis infections |
| TWI551295B (zh) | 2008-04-18 | 2016-10-01 | 英特威特國際股份有限公司 | 防備胞內勞森菌（Ｌａｗｓｏｎｉａ ｉｎｔｒａｃｅｌｌｕｌａｒｉｓ）用疫苗 |
| US20120321656A1 (en) * | 2011-06-20 | 2012-12-20 | Matthias Rath | Oligopeptides and their use for treating infectious diseases |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5885823A (en) * | 1995-06-05 | 1999-03-23 | Nobl Laboratories, Inc. | Lawsonia intracellularis cultivation, anti-Lawsonia intracellularis vaccines and diagnostic agents |
| CN1145697C (zh) * | 1995-11-30 | 2004-04-14 | 维多利亚农业服务控股公司 | 治疗和诊断组合物 |
-
2000
- 2000-05-11 AU AU43861/00A patent/AU775323B2/en not_active Ceased
- 2000-05-11 CA CA002372105A patent/CA2372105A1/en not_active Abandoned
- 2000-05-11 EP EP00924978A patent/EP1177213A4/en not_active Withdrawn
- 2000-05-11 NZ NZ515363A patent/NZ515363A/en unknown
- 2000-05-11 WO PCT/AU2000/000439 patent/WO2000069906A1/en not_active Application Discontinuation
- 2000-05-12 PE PE2000000447A patent/PE20010239A1/es not_active Application Discontinuation
-
2004
- 2004-10-27 AU AU2004224903A patent/AU2004224903A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1177213A1 (en) | 2002-02-06 |
| EP1177213A4 (en) | 2002-08-28 |
| CA2372105A1 (en) | 2000-11-23 |
| AU2004224903A1 (en) | 2004-11-25 |
| AU4386100A (en) | 2000-12-05 |
| AU775323B2 (en) | 2004-07-29 |
| WO2000069906A1 (en) | 2000-11-23 |
| NZ515363A (en) | 2003-07-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |