NO20006456L - En mutant human hepatitt B viral stamme og anvendelser derav - Google Patents

En mutant human hepatitt B viral stamme og anvendelser derav

Info

Publication number
NO20006456L
NO20006456L NO20006456A NO20006456A NO20006456L NO 20006456 L NO20006456 L NO 20006456L NO 20006456 A NO20006456 A NO 20006456A NO 20006456 A NO20006456 A NO 20006456A NO 20006456 L NO20006456 L NO 20006456L
Authority
NO
Norway
Prior art keywords
virus
hepatitis
nucleic acid
isolated nucleic
polypeptide
Prior art date
Application number
NO20006456A
Other languages
English (en)
Other versions
NO20006456D0 (no
Inventor
Chong Jin Oon
Gek Keow Lim
Yi Zhao
Wei Ning Chen
Original Assignee
Government Of The Republic Of Singapore
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Government Of The Republic Of Singapore filed Critical Government Of The Republic Of Singapore
Publication of NO20006456D0 publication Critical patent/NO20006456D0/no
Publication of NO20006456L publication Critical patent/NO20006456L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Denne oppfinnelse frembringer en isolert stamme med hepatitt B virus som er benevnt human hepatitt B virus overflateantigen -"S" - 133 Oon stamme (metionin til treonin), hvis inneholdende virusgenom er arkivert under tilgangsnummerene P97121501, P97121502 og P97121503 i den europeiske cellekultur samling den 15. desember 1997. Denne oppfinnelse frembringer også en isolert nukleinsyre som koder for et polypeptid som er et mutant stort overflate antigen på en stamme med hepatitt B virus, der nevnte polypeptid har en aminosyresekvens som skiller seg fra aminosyresekvensen til et stort overflateantigen fra et villtype hepatitt B virus i at aminosyren i posisjon 133 i et slikt polypeptid er treonin istedenfor metionin. Denne oppfinnelse frembringer også en isolert nukleinsyre som koder for et peptid, der peptidet blir kodet for av et nukleinsyremolekyl som omfatter nukleotidet 527 til og med 595 i SEQ.ID.No. 1 og det rensete peptid. Denne oppfinnelse frembringer også ulike fremgangsmåter for å bruke de beskrevne isolerte nukleinsyrer og peptider. Denne oppfinnelse frembringer videre ulike anvendelser av den beskrevne isolerte nukleinsyre, de beskrevne polypeptider og peptider, og antistoff.
NO20006456A 1998-06-19 2000-12-18 En mutant human hepatitt B viral stamme og anvendelser derav NO20006456L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/SG1998/000046 WO1999066048A1 (en) 1998-06-19 1998-06-19 A mutant human hepatitis b viral strain and uses thereof

Publications (2)

Publication Number Publication Date
NO20006456D0 NO20006456D0 (no) 2000-12-18
NO20006456L true NO20006456L (no) 2001-02-16

Family

ID=20429862

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20006456A NO20006456L (no) 1998-06-19 2000-12-18 En mutant human hepatitt B viral stamme og anvendelser derav

Country Status (22)

Country Link
US (1) US6558675B1 (no)
EP (1) EP1098981A1 (no)
JP (1) JP2002518014A (no)
KR (1) KR100498118B1 (no)
CN (1) CN1322251A (no)
AR (1) AR020093A1 (no)
AU (1) AU756866B2 (no)
BG (1) BG105066A (no)
BR (1) BR9815913A (no)
CA (1) CA2330935C (no)
HU (1) HUP0103409A3 (no)
IL (1) IL140364A0 (no)
IS (1) IS5778A (no)
MX (1) MXPA00012720A (no)
MY (1) MY118955A (no)
NO (1) NO20006456L (no)
NZ (1) NZ508890A (no)
PL (1) PL192129B1 (no)
TR (1) TR200003777T2 (no)
UA (1) UA73476C2 (no)
WO (1) WO1999066048A1 (no)
YU (1) YU80600A (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200643171A (en) 2005-06-07 2006-12-16 Temasek Life Sciences Lab Ltd Porcine circovirus type 2 vaccines
BR112022005687A2 (pt) 2019-09-30 2022-06-21 Gilead Sciences Inc Vacinas contra o hbv e métodos para tratar o hbv
CN113201051B (zh) * 2021-04-27 2022-08-02 复旦大学 一种乙肝病毒表面蛋白突变体及其在抗乙肝病毒中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9401987D0 (en) * 1994-02-02 1994-03-30 Imperial College Modified nucleic acid
US5980901A (en) * 1996-09-18 1999-11-09 The Board Of Regents Of The University Of Texas System Viral defective interfering particles and uses thereof

Also Published As

Publication number Publication date
MY118955A (en) 2005-02-28
TR200003777T2 (tr) 2001-06-21
CN1322251A (zh) 2001-11-14
BR9815913A (pt) 2001-12-26
NZ508890A (en) 2004-04-30
WO1999066048A1 (en) 1999-12-23
KR100498118B1 (ko) 2005-07-01
AU756866B2 (en) 2003-01-23
IS5778A (is) 2000-12-19
JP2002518014A (ja) 2002-06-25
PL345573A1 (en) 2001-12-17
HUP0103409A2 (hu) 2001-12-28
IL140364A0 (en) 2002-02-10
US6558675B1 (en) 2003-05-06
AR020093A1 (es) 2002-04-10
NO20006456D0 (no) 2000-12-18
BG105066A (en) 2001-09-28
HUP0103409A3 (en) 2003-10-28
UA73476C2 (en) 2005-08-15
EP1098981A1 (en) 2001-05-16
CA2330935C (en) 2005-05-10
KR20010106129A (ko) 2001-11-29
CA2330935A1 (en) 1999-12-23
MXPA00012720A (es) 2002-05-08
YU80600A (sh) 2005-06-10
PL192129B1 (pl) 2006-09-29
AU7795198A (en) 2000-01-05

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