BR9815913A - Cepa viral de hepatite b humana mutante e seususos - Google Patents
Cepa viral de hepatite b humana mutante e seususosInfo
- Publication number
- BR9815913A BR9815913A BR9815913-5A BR9815913A BR9815913A BR 9815913 A BR9815913 A BR 9815913A BR 9815913 A BR9815913 A BR 9815913A BR 9815913 A BR9815913 A BR 9815913A
- Authority
- BR
- Brazil
- Prior art keywords
- present
- provides
- virus
- nucleic acid
- hepatitis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- General Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
"CEPA VIRAL DE HEPATITE B HUMANA MUTANTE E SEUSUSOS". A presente invenção fornece uma cepa isolada de vírusda Hepatite B designada Cepa Oon 'S'-133-Antigeno Superficial deVirus da Hepatite B Humana (Metionina para Treonina) cujogenona viral constituinte é depositado sob os Nos. de AcessãoP97121501, P97121502 e P97121503 na European Collection ofCell Culture em 15 de dezembro de 1997. A presente invençãotambém provê um ácido nucléico isolado codificando umpolipeptideo que é um antigeno superficial principal, mutante, deuma cepa do vírus de hepatite B, tal polipeptideo tendo umaseq³ência de aminoácidos que difere da seq³ência deaminoácidos de um antígeno superficial principal de um vírus dehepatite B do tipo selvagem em que o aminoácido na posiçãonumero 133 do referido polipeptídeo é uma treonina em vez deuma metionina. A presente invenção provê também um ácidonucléico isolado que codifica um peptídeo, onde o peptídeo écodificado por uma molécula de ácido nucléico compreendendonucleotídeos 527 até 595 da SEQ. ID. NO. 1, e o peptídeopurificado. A presente invenção também provê vários métodos deutilizar os peptídeos e ácidos nucléicos isolados, revelados. Apresente invenção também provê vários usos do ácido nucléicoisolado, revelado, polipeptídeos e peptídeos, e anticorpos.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/SG1998/000046 WO1999066048A1 (en) | 1998-06-19 | 1998-06-19 | A mutant human hepatitis b viral strain and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9815913A true BR9815913A (pt) | 2001-12-26 |
Family
ID=20429862
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9815913-5A BR9815913A (pt) | 1998-06-19 | 1998-06-19 | Cepa viral de hepatite b humana mutante e seususos |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US6558675B1 (pt) |
| EP (1) | EP1098981A1 (pt) |
| JP (1) | JP2002518014A (pt) |
| KR (1) | KR100498118B1 (pt) |
| CN (1) | CN1322251A (pt) |
| AR (1) | AR020093A1 (pt) |
| AU (1) | AU756866B2 (pt) |
| BG (1) | BG105066A (pt) |
| BR (1) | BR9815913A (pt) |
| CA (1) | CA2330935C (pt) |
| HU (1) | HUP0103409A3 (pt) |
| IL (1) | IL140364A0 (pt) |
| IS (1) | IS5778A (pt) |
| MX (1) | MXPA00012720A (pt) |
| MY (1) | MY118955A (pt) |
| NO (1) | NO20006456L (pt) |
| NZ (1) | NZ508890A (pt) |
| PL (1) | PL192129B1 (pt) |
| TR (1) | TR200003777T2 (pt) |
| UA (1) | UA73476C2 (pt) |
| WO (1) | WO1999066048A1 (pt) |
| YU (1) | YU80600A (pt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200643171A (en) | 2005-06-07 | 2006-12-16 | Temasek Life Sciences Lab Ltd | Porcine circovirus type 2 vaccines |
| US11497808B2 (en) | 2019-09-30 | 2022-11-15 | Gilead Sciences, Inc. | HBV vaccines and methods treating HBV |
| CN113201051B (zh) * | 2021-04-27 | 2022-08-02 | 复旦大学 | 一种乙肝病毒表面蛋白突变体及其在抗乙肝病毒中的应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9401987D0 (en) | 1994-02-02 | 1994-03-30 | Imperial College | Modified nucleic acid |
| AU4353897A (en) | 1996-09-18 | 1998-04-14 | Board Of Regents, The University Of Texas System | Viral defective interfering particles and uses thereof |
-
1998
- 1998-06-19 US US09/719,528 patent/US6558675B1/en not_active Expired - Fee Related
- 1998-06-19 NZ NZ508890A patent/NZ508890A/en unknown
- 1998-06-19 CN CN98814201A patent/CN1322251A/zh active Pending
- 1998-06-19 JP JP2000554857A patent/JP2002518014A/ja active Pending
- 1998-06-19 IL IL14036498A patent/IL140364A0/xx unknown
- 1998-06-19 YU YU80600A patent/YU80600A/sh unknown
- 1998-06-19 PL PL345573A patent/PL192129B1/pl not_active IP Right Cessation
- 1998-06-19 TR TR2000/03777T patent/TR200003777T2/xx unknown
- 1998-06-19 MX MXPA00012720A patent/MXPA00012720A/es not_active Application Discontinuation
- 1998-06-19 CA CA002330935A patent/CA2330935C/en not_active Expired - Fee Related
- 1998-06-19 HU HU0103409A patent/HUP0103409A3/hu unknown
- 1998-06-19 WO PCT/SG1998/000046 patent/WO1999066048A1/en not_active Application Discontinuation
- 1998-06-19 AU AU77951/98A patent/AU756866B2/en not_active Ceased
- 1998-06-19 BR BR9815913-5A patent/BR9815913A/pt not_active Application Discontinuation
- 1998-06-19 EP EP98926023A patent/EP1098981A1/en not_active Withdrawn
- 1998-06-19 KR KR10-2000-7014456A patent/KR100498118B1/ko not_active IP Right Cessation
- 1998-06-19 UA UA2000127297A patent/UA73476C2/uk unknown
-
1999
- 1999-06-18 AR ARP990102962A patent/AR020093A1/es unknown
- 1999-06-18 MY MYPI99002517A patent/MY118955A/en unknown
-
2000
- 2000-12-18 NO NO20006456A patent/NO20006456L/no not_active Application Discontinuation
- 2000-12-18 BG BG105066A patent/BG105066A/xx unknown
- 2000-12-19 IS IS5778A patent/IS5778A/is unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TR200003777T2 (tr) | 2001-06-21 |
| AU756866B2 (en) | 2003-01-23 |
| IS5778A (is) | 2000-12-19 |
| KR20010106129A (ko) | 2001-11-29 |
| WO1999066048A1 (en) | 1999-12-23 |
| NO20006456L (no) | 2001-02-16 |
| CN1322251A (zh) | 2001-11-14 |
| YU80600A (sh) | 2005-06-10 |
| HUP0103409A2 (hu) | 2001-12-28 |
| NO20006456D0 (no) | 2000-12-18 |
| CA2330935A1 (en) | 1999-12-23 |
| NZ508890A (en) | 2004-04-30 |
| JP2002518014A (ja) | 2002-06-25 |
| CA2330935C (en) | 2005-05-10 |
| PL345573A1 (en) | 2001-12-17 |
| PL192129B1 (pl) | 2006-09-29 |
| EP1098981A1 (en) | 2001-05-16 |
| UA73476C2 (en) | 2005-08-15 |
| MY118955A (en) | 2005-02-28 |
| AR020093A1 (es) | 2002-04-10 |
| US6558675B1 (en) | 2003-05-06 |
| BG105066A (en) | 2001-09-28 |
| IL140364A0 (en) | 2002-02-10 |
| MXPA00012720A (es) | 2002-05-08 |
| KR100498118B1 (ko) | 2005-07-01 |
| HUP0103409A3 (en) | 2003-10-28 |
| AU7795198A (en) | 2000-01-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: DE ACORDO COM O ART 36 DA LPI (LEI 9.279/96) 2O, O PEDIDO VOLTA A EXAME SENDO CONSIDERADO NAO PATENTEAVEL PELAS RAZOES EXPOSTAS NO PARECER TECNICO ANTERIOR. |