AR020093A1 - Una cepa aislada de virus de hepatitis, acido nucleico aislado que codifica un polipeptido de la cepa, vector que comprende dicho acido nucleico, sistemavector huesped para la produccion del polipeptido, el polipeptido, metodo para su produccion, oligonucleotido para hibridarse con el acido nucleico - Google Patents
Una cepa aislada de virus de hepatitis, acido nucleico aislado que codifica un polipeptido de la cepa, vector que comprende dicho acido nucleico, sistemavector huesped para la produccion del polipeptido, el polipeptido, metodo para su produccion, oligonucleotido para hibridarse con el acido nucleicoInfo
- Publication number
- AR020093A1 AR020093A1 ARP990102962A ARP990102962A AR020093A1 AR 020093 A1 AR020093 A1 AR 020093A1 AR P990102962 A ARP990102962 A AR P990102962A AR P990102962 A ARP990102962 A AR P990102962A AR 020093 A1 AR020093 A1 AR 020093A1
- Authority
- AR
- Argentina
- Prior art keywords
- polypeptide
- virus
- strain
- nucleic acid
- isolated
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- General Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Una cepa aislada del virus de hepatitis, un ácido nucleico aislado que codifica un polipéptido de la cepa aislada de virus, un vector que comprende dichoácido nucleico, un sistema vector huésped para la produccion de polipéptido de la cepa aislada devirus, un método para producir dicho polipéptido, un métodopara producir un péptido, un polipéptido de dicha cepa aislada de virus, un oligonucleotido para hibridarse dentro del ácido nucleico, método para obtneranticuerpos paa el polipéptido, un anticuerpo obtenido por el método, un método paa determinar la infeccion en un sujeto, un método para identificar uncompuesto químico, una composicion que comprende un péptido, un método para tratar un sujeto infectado, un método para evitar una infeccion, un método pararastrear fluidos en el sujeto, una vacuna contra hepatitis que comprende la cepa del virus de hepatitis. Esta invencion provee una cepa aislada de virus dehepatitis B designada antígeno de superficie de virus de hepatitis B humana-cepaS133 Oon (metionina a trionina) cuyo genoma viral constituyente estádepositado bajo los numeros de acceso P97121501, P97121502 y P97212503 en la Coleccion Europea de Cultivos de Células el 15 de diciembre de 1997. Estainvencion provee también unácido nucleico aislado que codifica un polipéptido que es un antígeno mayor mutante de superficie de una cepa de virus de hepatitisB. La aislacion del virus mutante permite el secuenciado de los ácidos nucleicos y los polipéptidos de los virus los cuales a cambio permiten la produccion devarios métodos los cuales no son posibles previo a la aislacion del virus. Estos métodos incluyen, pero no son limitantes a los métodos de deteccion deinfeccion, métodos de tratamiento.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/SG1998/000046 WO1999066048A1 (en) | 1998-06-19 | 1998-06-19 | A mutant human hepatitis b viral strain and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR020093A1 true AR020093A1 (es) | 2002-04-10 |
Family
ID=20429862
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP990102962A AR020093A1 (es) | 1998-06-19 | 1999-06-18 | Una cepa aislada de virus de hepatitis, acido nucleico aislado que codifica un polipeptido de la cepa, vector que comprende dicho acido nucleico, sistemavector huesped para la produccion del polipeptido, el polipeptido, metodo para su produccion, oligonucleotido para hibridarse con el acido nucleico |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US6558675B1 (es) |
| EP (1) | EP1098981A1 (es) |
| JP (1) | JP2002518014A (es) |
| KR (1) | KR100498118B1 (es) |
| CN (1) | CN1322251A (es) |
| AR (1) | AR020093A1 (es) |
| AU (1) | AU756866B2 (es) |
| BG (1) | BG105066A (es) |
| BR (1) | BR9815913A (es) |
| CA (1) | CA2330935C (es) |
| HU (1) | HUP0103409A3 (es) |
| IL (1) | IL140364A0 (es) |
| IS (1) | IS5778A (es) |
| MX (1) | MXPA00012720A (es) |
| MY (1) | MY118955A (es) |
| NO (1) | NO20006456L (es) |
| NZ (1) | NZ508890A (es) |
| PL (1) | PL192129B1 (es) |
| TR (1) | TR200003777T2 (es) |
| UA (1) | UA73476C2 (es) |
| WO (1) | WO1999066048A1 (es) |
| YU (1) | YU80600A (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200643171A (en) | 2005-06-07 | 2006-12-16 | Temasek Life Sciences Lab Ltd | Porcine circovirus type 2 vaccines |
| US11497808B2 (en) | 2019-09-30 | 2022-11-15 | Gilead Sciences, Inc. | HBV vaccines and methods treating HBV |
| CN113201051B (zh) * | 2021-04-27 | 2022-08-02 | 复旦大学 | 一种乙肝病毒表面蛋白突变体及其在抗乙肝病毒中的应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9401987D0 (en) | 1994-02-02 | 1994-03-30 | Imperial College | Modified nucleic acid |
| EP0969863A4 (en) | 1996-09-18 | 2001-11-07 | Univ Texas | DEFECTIVE VIRAL INTERFERENCE PARTICLES AND THEIR USE. |
-
1998
- 1998-06-19 TR TR2000/03777T patent/TR200003777T2/xx unknown
- 1998-06-19 WO PCT/SG1998/000046 patent/WO1999066048A1/en not_active Application Discontinuation
- 1998-06-19 EP EP98926023A patent/EP1098981A1/en not_active Withdrawn
- 1998-06-19 HU HU0103409A patent/HUP0103409A3/hu unknown
- 1998-06-19 CA CA002330935A patent/CA2330935C/en not_active Expired - Fee Related
- 1998-06-19 YU YU80600A patent/YU80600A/sh unknown
- 1998-06-19 KR KR10-2000-7014456A patent/KR100498118B1/ko not_active IP Right Cessation
- 1998-06-19 US US09/719,528 patent/US6558675B1/en not_active Expired - Fee Related
- 1998-06-19 PL PL345573A patent/PL192129B1/pl not_active IP Right Cessation
- 1998-06-19 CN CN98814201A patent/CN1322251A/zh active Pending
- 1998-06-19 BR BR9815913-5A patent/BR9815913A/pt not_active Application Discontinuation
- 1998-06-19 AU AU77951/98A patent/AU756866B2/en not_active Ceased
- 1998-06-19 IL IL14036498A patent/IL140364A0/xx unknown
- 1998-06-19 MX MXPA00012720A patent/MXPA00012720A/es not_active Application Discontinuation
- 1998-06-19 NZ NZ508890A patent/NZ508890A/en unknown
- 1998-06-19 UA UA2000127297A patent/UA73476C2/uk unknown
- 1998-06-19 JP JP2000554857A patent/JP2002518014A/ja active Pending
-
1999
- 1999-06-18 AR ARP990102962A patent/AR020093A1/es unknown
- 1999-06-18 MY MYPI99002517A patent/MY118955A/en unknown
-
2000
- 2000-12-18 BG BG105066A patent/BG105066A/xx unknown
- 2000-12-18 NO NO20006456A patent/NO20006456L/no not_active Application Discontinuation
- 2000-12-19 IS IS5778A patent/IS5778A/is unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BG105066A (en) | 2001-09-28 |
| WO1999066048A1 (en) | 1999-12-23 |
| CA2330935C (en) | 2005-05-10 |
| YU80600A (sh) | 2005-06-10 |
| KR100498118B1 (ko) | 2005-07-01 |
| HUP0103409A2 (hu) | 2001-12-28 |
| BR9815913A (pt) | 2001-12-26 |
| AU7795198A (en) | 2000-01-05 |
| NZ508890A (en) | 2004-04-30 |
| US6558675B1 (en) | 2003-05-06 |
| NO20006456L (no) | 2001-02-16 |
| CA2330935A1 (en) | 1999-12-23 |
| CN1322251A (zh) | 2001-11-14 |
| AU756866B2 (en) | 2003-01-23 |
| EP1098981A1 (en) | 2001-05-16 |
| IS5778A (is) | 2000-12-19 |
| PL345573A1 (en) | 2001-12-17 |
| PL192129B1 (pl) | 2006-09-29 |
| IL140364A0 (en) | 2002-02-10 |
| TR200003777T2 (tr) | 2001-06-21 |
| MY118955A (en) | 2005-02-28 |
| UA73476C2 (en) | 2005-08-15 |
| JP2002518014A (ja) | 2002-06-25 |
| MXPA00012720A (es) | 2002-05-08 |
| KR20010106129A (ko) | 2001-11-29 |
| HUP0103409A3 (en) | 2003-10-28 |
| NO20006456D0 (no) | 2000-12-18 |
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