AR062300A2 - Polipeptido que comprende una porcion inmunogenica de una proteina de prostata o su variante, molecula de adn, vector de expresion, celula huesped composicion farmaceutica, vacuna uso de dichas composiciones y vacunas para preparar medicamentos y proteina de fusion - Google Patents
Polipeptido que comprende una porcion inmunogenica de una proteina de prostata o su variante, molecula de adn, vector de expresion, celula huesped composicion farmaceutica, vacuna uso de dichas composiciones y vacunas para preparar medicamentos y proteina de fusionInfo
- Publication number
- AR062300A2 AR062300A2 ARP070103521A ARP070103521A AR062300A2 AR 062300 A2 AR062300 A2 AR 062300A2 AR P070103521 A ARP070103521 A AR P070103521A AR P070103521 A ARP070103521 A AR P070103521A AR 062300 A2 AR062300 A2 AR 062300A2
- Authority
- AR
- Argentina
- Prior art keywords
- vaccines
- protein
- compositions
- polypeptide
- variant
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 6
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 6
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 6
- 108090000623 proteins and genes Proteins 0.000 title abstract 5
- 102000004169 proteins and genes Human genes 0.000 title abstract 5
- 229960005486 vaccine Drugs 0.000 title abstract 4
- 210000002307 prostate Anatomy 0.000 title abstract 3
- 239000003814 drug Substances 0.000 title abstract 2
- 239000013604 expression vector Substances 0.000 title abstract 2
- 230000002163 immunogen Effects 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 3
- 108020004414 DNA Proteins 0.000 abstract 2
- 102000053602 DNA Human genes 0.000 abstract 1
- 206010060862 Prostate cancer Diseases 0.000 abstract 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 238000002619 cancer immunotherapy Methods 0.000 abstract 1
- 230000004927 fusion Effects 0.000 abstract 1
- 108020001507 fusion proteins Proteins 0.000 abstract 1
- 102000037865 fusion proteins Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- General Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Polipéptidos que contienen por lo menos una porcion de una proteína de prostata. También se dan a conocer vacunas y composiciones farmacéuticas para la inmunoterapia del cáncer de prostata que comprenden tales polipéptidos, moléculas de ADN que codifican tales polipéptidos, vectores de expresion, células huésped, el uso de dichas composiciones y vacunas para preparar medicamentos, y una proteína de fusion. Reivindicacion 1: Un polipéptido que comprende una porcion inmunogénica de una proteína de prostata o su variante, caracterizado porque dicha proteína comprende a una secuencia de aminoácido codificada por una molécula de ADN que tiene una secuencia seleccionada del grupo formado por las secuencias de nucleotido enumeradas en los NRs ID de Sec: 2, 3, 8-29, 41-45, 47-52, 54-65, 70, 73-74, 79, 81, 87, 90, 92, 93, 97, 103, 104, 107, 109-111, 115-160, 171, 173-175 y 177, los complementos de dichas secuencias de nucleotido y las variantes de dichas secuencias de nucleotido. Reivindicacion 19: Una proteína de fusion caracterizada porque comprende a dos o más polipéptidos de acuerdo con la reivindicacion 1.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US80609997A | 1997-02-25 | 1997-02-25 | |
US90480497A | 1997-08-01 | 1997-08-01 | |
US09/020,956 US6261562B1 (en) | 1997-02-25 | 1998-02-09 | Compounds for immunotherapy of prostate cancer and methods for their use |
Publications (1)
Publication Number | Publication Date |
---|---|
AR062300A2 true AR062300A2 (es) | 2008-10-29 |
Family
ID=27122845
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP980100838A AR008727A1 (es) | 1997-02-25 | 1998-02-25 | COMPOSICIONES Y PROTEINAS DE FUSIoN QUE COMPRENDEN UN POLIPEPTIDO QUE COMPRENDE UNA PORCION INMUNOGENICA DE UNA PROTEINA DE PROSTATA O SU VARIANTE, Y USOS DE LAS MISMAS PARA PREPARAR UN MEDICAMENTO |
ARP070103521A AR062300A2 (es) | 1997-02-25 | 2007-08-09 | Polipeptido que comprende una porcion inmunogenica de una proteina de prostata o su variante, molecula de adn, vector de expresion, celula huesped composicion farmaceutica, vacuna uso de dichas composiciones y vacunas para preparar medicamentos y proteina de fusion |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP980100838A AR008727A1 (es) | 1997-02-25 | 1998-02-25 | COMPOSICIONES Y PROTEINAS DE FUSIoN QUE COMPRENDEN UN POLIPEPTIDO QUE COMPRENDE UNA PORCION INMUNOGENICA DE UNA PROTEINA DE PROSTATA O SU VARIANTE, Y USOS DE LAS MISMAS PARA PREPARAR UN MEDICAMENTO |
Country Status (8)
Country | Link |
---|---|
US (1) | US6261562B1 (es) |
EP (2) | EP2298877B1 (es) |
KR (1) | KR100572817B1 (es) |
AR (2) | AR008727A1 (es) |
CA (1) | CA2742641A1 (es) |
CO (1) | CO4850588A1 (es) |
SA (1) | SA98190265B1 (es) |
TW (1) | TW581808B (es) |
Families Citing this family (53)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060024301A1 (en) * | 1997-02-25 | 2006-02-02 | Corixa Corporation | Prostate-specific polypeptides and fusion polypeptides thereof |
US6657056B2 (en) * | 1997-02-25 | 2003-12-02 | Corixa Corporation | Compounds for immunotherapy of prostate cancer and methods for their use |
US7202342B1 (en) | 1999-11-12 | 2007-04-10 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of prostate cancer |
US7517952B1 (en) | 1997-02-25 | 2009-04-14 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of prostate cancer |
US20030185830A1 (en) * | 1997-02-25 | 2003-10-02 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of prostate cancer |
CA2286304C (en) | 1997-04-10 | 2007-08-07 | Diagnocure Inc. | Pca3, pca3 genes, and methods of use |
US20020106688A1 (en) * | 1997-08-05 | 2002-08-08 | Moncef Jenboubi | Identification of gene sequences and gene products and their specific function and relationship to pathologies in a mammal |
US6623923B1 (en) * | 1998-12-23 | 2003-09-23 | Corixa Corporation | Compounds for immunotherapy and diagnosis of colon cancer and methods for their use |
US7063959B1 (en) * | 1998-12-30 | 2006-06-20 | Beth Israel Deaconess Medical Center, Inc. | Compositions of the SOC/CRAC calcium channel protein family |
WO2000071711A2 (en) * | 1999-05-20 | 2000-11-30 | Fahri Saatcioglu | Differentially expressed genes in prostate cancer |
ES2260059T3 (es) * | 1999-09-29 | 2006-11-01 | Diagnocure Inc. | Rna mensajero del pca3 en tejidos benignos y malignos de prostata. |
US7611892B2 (en) * | 2000-03-24 | 2009-11-03 | President And Fellows Of Harvard College | Prostate-specific or testis-specific nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods |
US8036731B2 (en) | 2001-01-22 | 2011-10-11 | Spectrum Dynamics Llc | Ingestible pill for diagnosing a gastrointestinal tract |
US8909325B2 (en) | 2000-08-21 | 2014-12-09 | Biosensors International Group, Ltd. | Radioactive emission detector equipped with a position tracking system and utilization thereof with medical systems and in medical procedures |
WO2004042546A1 (en) * | 2002-11-04 | 2004-05-21 | V-Target Technologies Ltd. | Apparatus and methods for imaging and attenuation correction |
US8489176B1 (en) | 2000-08-21 | 2013-07-16 | Spectrum Dynamics Llc | Radioactive emission detector equipped with a position tracking system and utilization thereof with medical systems and in medical procedures |
US8565860B2 (en) | 2000-08-21 | 2013-10-22 | Biosensors International Group, Ltd. | Radioactive emission detector equipped with a position tracking system |
WO2002027324A2 (en) * | 2000-09-28 | 2002-04-04 | Millennium Pharmaceuticals, Inc. | METHODS OF USE OF ALPHA-METHYLACYL-CoA RACEMASE IN HORMONE REFRACTORY AND METASTATIC PROSTATE CANCERS |
US7048931B1 (en) * | 2000-11-09 | 2006-05-23 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of prostate cancer |
IL157007A0 (en) | 2001-01-22 | 2004-02-08 | Target Technologies Ltd V | Ingestible device |
WO2002089747A2 (en) | 2001-05-09 | 2002-11-14 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of prostate cancer |
US6897024B2 (en) * | 2001-05-31 | 2005-05-24 | Stichting Katholieke Universiteit More Particularly The University Medical Centre Nijmegen | Nucleic acid molecules comprising the promoter for PCA3, and uses thereof |
US20040116807A1 (en) * | 2002-10-17 | 2004-06-17 | Roni Amrami | Blood vessels wall imaging catheter |
WO2004070056A2 (en) | 2003-02-07 | 2004-08-19 | Diagnocure Inc. | Method to detect prostate cancer in a sample |
KR20060073589A (ko) * | 2003-08-07 | 2006-06-28 | 카이론 코포레이션 | 항암 치료법을 위한 표적으로서 트레포일 인자 3(tff3) |
US9040016B2 (en) | 2004-01-13 | 2015-05-26 | Biosensors International Group, Ltd. | Diagnostic kit and methods for radioimaging myocardial perfusion |
US9470801B2 (en) | 2004-01-13 | 2016-10-18 | Spectrum Dynamics Llc | Gating with anatomically varying durations |
US8571881B2 (en) | 2004-11-09 | 2013-10-29 | Spectrum Dynamics, Llc | Radiopharmaceutical dispensing, administration, and imaging |
CN1981210A (zh) * | 2004-01-13 | 2007-06-13 | 光谱动力学有限责任公司 | 多维图像重构 |
US7968851B2 (en) | 2004-01-13 | 2011-06-28 | Spectrum Dynamics Llc | Dynamic spect camera |
US8586932B2 (en) | 2004-11-09 | 2013-11-19 | Spectrum Dynamics Llc | System and method for radioactive emission measurement |
WO2006075333A2 (en) | 2005-01-13 | 2006-07-20 | Spectrum Dynamics Llc | Multi-dimensional image reconstruction and analysis for expert-system diagnosis |
EP1766550A2 (en) | 2004-06-01 | 2007-03-28 | Spectrum Dynamics LLC | Methods of view selection for radioactive emission measurements |
EP1778957A4 (en) | 2004-06-01 | 2015-12-23 | Biosensors Int Group Ltd | OPTIMIZING THE MEASUREMENT OF RADIOACTIVE EMISSIONS IN SPECIFIC BODY STRUCTURES |
US8000773B2 (en) | 2004-11-09 | 2011-08-16 | Spectrum Dynamics Llc | Radioimaging |
US9316743B2 (en) | 2004-11-09 | 2016-04-19 | Biosensors International Group, Ltd. | System and method for radioactive emission measurement |
US9943274B2 (en) | 2004-11-09 | 2018-04-17 | Spectrum Dynamics Medical Limited | Radioimaging using low dose isotope |
US8615405B2 (en) | 2004-11-09 | 2013-12-24 | Biosensors International Group, Ltd. | Imaging system customization using data from radiopharmaceutical-associated data carrier |
EP1827505A4 (en) | 2004-11-09 | 2017-07-12 | Biosensors International Group, Ltd. | Radioimaging |
US20080260637A1 (en) * | 2004-11-17 | 2008-10-23 | Dalia Dickman | Methods of Detecting Prostate Cancer |
WO2008059489A2 (en) | 2006-11-13 | 2008-05-22 | Spectrum Dynamics Llc | Radioimaging applications of and novel formulations of teboroxime |
CA2491067A1 (en) * | 2004-12-24 | 2006-06-24 | Stichting Katholieke Universiteit | Mrna rations in urinary sediments and/or urine as a prognostic marker for prostate cancer |
US8837793B2 (en) | 2005-07-19 | 2014-09-16 | Biosensors International Group, Ltd. | Reconstruction stabilizer and active vision |
US8644910B2 (en) | 2005-07-19 | 2014-02-04 | Biosensors International Group, Ltd. | Imaging protocols |
EP1908011B1 (en) | 2005-07-19 | 2013-09-04 | Spectrum Dynamics LLC | Reconstruction stabilizer and active vision |
EP1952180B1 (en) * | 2005-11-09 | 2017-01-04 | Biosensors International Group, Ltd. | Dynamic spect camera |
WO2007074466A2 (en) | 2005-12-28 | 2007-07-05 | Starhome Gmbh | Late forwarding to local voicemail system of calls to roaming users |
US8894974B2 (en) | 2006-05-11 | 2014-11-25 | Spectrum Dynamics Llc | Radiopharmaceuticals for diagnosis and therapy |
WO2008075362A2 (en) | 2006-12-20 | 2008-06-26 | Spectrum Dynamics Llc | A method, a system, and an apparatus for using and processing multidimensional data |
US8521253B2 (en) | 2007-10-29 | 2013-08-27 | Spectrum Dynamics Llc | Prostate imaging |
KR20120036842A (ko) * | 2009-05-12 | 2012-04-18 | 코닌클리케 필립스 일렉트로닉스 엔.브이. | 악성의 호르몬 민감성 전립선 암에 대한 마커로서의 포스포디에스테라제 4d7 |
US8338788B2 (en) | 2009-07-29 | 2012-12-25 | Spectrum Dynamics Llc | Method and system of optimized volumetric imaging |
RU2461916C1 (ru) * | 2011-01-12 | 2012-09-20 | Государственное образовательное учреждение высшего профессионального образования Томский государственный университет систем управления и радиоэлектроники (ТУСУР) | Полупроводниковый светоизлучающий прибор |
Family Cites Families (57)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2095698A (en) | 1937-10-12 | Ox yoke model | ||
US4489710A (en) | 1981-06-23 | 1984-12-25 | Xoma Corporation | Composition and method for transplantation therapy |
US4429008B1 (en) | 1981-12-10 | 1995-05-16 | Univ California | Thiol reactive liposomes |
US4769330A (en) | 1981-12-24 | 1988-09-06 | Health Research, Incorporated | Modified vaccinia virus and methods for making and using the same |
US4603112A (en) | 1981-12-24 | 1986-07-29 | Health Research, Incorporated | Modified vaccinia virus |
US4671958A (en) | 1982-03-09 | 1987-06-09 | Cytogen Corporation | Antibody conjugates for the delivery of compounds to target sites |
JPS59116229A (ja) | 1982-12-24 | 1984-07-05 | Teijin Ltd | 細胞毒性複合体を活性成分とする癌治療用剤およびその製造法 |
US4673562A (en) | 1983-08-19 | 1987-06-16 | The Children's Medical Center Corporation | Bisamide bisthiol compounds useful for making technetium radiodiagnostic renal agents |
US4873088A (en) | 1983-09-06 | 1989-10-10 | Liposome Technology, Inc. | Liposome drug delivery method and composition |
US4625014A (en) | 1984-07-10 | 1986-11-25 | Dana-Farber Cancer Institute, Inc. | Cell-delivery agent |
US4542225A (en) | 1984-08-29 | 1985-09-17 | Dana-Farber Cancer Institute, Inc. | Acid-cleavable compound |
US4638045A (en) | 1985-02-19 | 1987-01-20 | Massachusetts Institute Of Technology | Non-peptide polyamino acid bioerodible polymers |
US4751180A (en) | 1985-03-28 | 1988-06-14 | Chiron Corporation | Expression using fused genes providing for protein product |
GB8508845D0 (en) | 1985-04-04 | 1985-05-09 | Hoffmann La Roche | Vaccinia dna |
US4777127A (en) | 1985-09-30 | 1988-10-11 | Labsystems Oy | Human retrovirus-related products and methods of diagnosing and treating conditions associated with said retrovirus |
US4935233A (en) | 1985-12-02 | 1990-06-19 | G. D. Searle And Company | Covalently linked polypeptide cell modulators |
US4699784A (en) | 1986-02-25 | 1987-10-13 | Center For Molecular Medicine & Immunology | Tumoricidal methotrexate-antibody conjugate |
US5075109A (en) | 1986-10-24 | 1991-12-24 | Southern Research Institute | Method of potentiating an immune response |
GB8702816D0 (en) | 1987-02-07 | 1987-03-11 | Al Sumidaie A M K | Obtaining retrovirus-containing fraction |
US4735792A (en) | 1987-04-28 | 1988-04-05 | The United States Of America As Represented By The United States Department Of Energy | Radioiodinated maleimides and use as agents for radiolabeling antibodies |
US4897268A (en) | 1987-08-03 | 1990-01-30 | Southern Research Institute | Drug delivery system and method of making the same |
WO1989001973A2 (en) | 1987-09-02 | 1989-03-09 | Applied Biotechnology, Inc. | Recombinant pox virus for immunization against tumor-associated antigens |
US5041289A (en) | 1987-11-13 | 1991-08-20 | Becton Dickinson And Company | Method of purging residual tumor cells in vitro with lymphokine activated cytotoxic cells |
JPH04505547A (ja) | 1988-01-04 | 1992-10-01 | イー・アイ・デユポン・ド・ネモアース・アンド・コンパニー | 細胞混合物から特定の細胞を単離するための多段アフィニティー法 |
US5215926A (en) | 1988-06-03 | 1993-06-01 | Cellpro, Inc. | Procedure for designing efficient affinity cell separation processes |
AP129A (en) | 1988-06-03 | 1991-04-17 | Smithkline Biologicals S A | Expression of retrovirus gag protein eukaryotic cells |
DK0465529T3 (da) | 1989-03-21 | 1998-10-05 | Vical Inc | Ekspression af exogene polynukleotidsekvenser i et hvirveldyr |
EP0487587A1 (en) | 1989-08-18 | 1992-06-03 | Chiron Corporation | Recombinant retroviruses delivering vector constructs to target cells |
WO1991016116A1 (en) | 1990-04-23 | 1991-10-31 | Cellpro Incorporated | Immunoselection device and method |
DE69126620T2 (de) | 1990-10-18 | 1997-10-02 | Cellpro Inc | Vorrichtung und verfahren zur trennung von partikeln mittels eines biegsamen gefässes |
US5851764A (en) | 1990-10-25 | 1998-12-22 | The Trustees Of Columbia University In The City Of New York | Human prostate tumor inducing gene-1 and uses thereof |
US5240856A (en) | 1991-10-23 | 1993-08-31 | Cellpro Incorporated | Apparatus for cell separation |
AU3467493A (en) | 1992-01-27 | 1993-09-01 | Board Of Trustees Of The Leland Stanford Junior University | Histamine derivatives and methods for their use |
US5428011A (en) | 1992-06-16 | 1995-06-27 | Procyon Biopharma, Inc. | Pharmaceutical preparations for inhibiting tumours associated with prostate adenocarcinoma |
US5786148A (en) | 1996-11-05 | 1998-07-28 | Incyte Pharmaceuticals, Inc. | Polynucleotides encoding a novel prostate-specific kallikrein |
ES2276390T3 (es) | 1992-11-05 | 2007-06-16 | Sloan-Kettering Institute For Cancer Research | Antigeno de membrana especifico de la prostata. |
US5359681A (en) | 1993-01-11 | 1994-10-25 | University Of Washington | Fiber optic sensor and methods and apparatus relating thereto |
ATE303160T1 (de) | 1993-08-11 | 2005-09-15 | Jenner Technologies | Impfstoff gegen prostatakrebs |
EP0652014A1 (en) | 1993-11-10 | 1995-05-10 | National Institute Of Immunology | Treatment of prostatic hypertrophy |
CA2153480A1 (en) | 1993-11-12 | 1995-06-01 | Kenichi Matsubara | Gene signature |
WO1995030758A1 (en) | 1994-05-10 | 1995-11-16 | Mayo Foundation For Medical Education And Research | Recombinant hk2 polypeptide |
AU728186B2 (en) | 1996-03-15 | 2001-01-04 | Corixa Corporation | Compounds and methods for immunotherapy and immunodiagnosis of prostate cancer |
US5955306A (en) | 1996-09-17 | 1999-09-21 | Millenium Pharmaceuticals, Inc. | Genes encoding proteins that interact with the tub protein |
CA2269755A1 (en) | 1996-10-25 | 1998-04-30 | Genetics Institute, Inc. | Secreted proteins and polynucleotides encoding them |
WO1998031799A2 (en) | 1997-01-21 | 1998-07-23 | Human Genome Sciences, Inc. | Polynucleotides and polypeptides encoding receptors |
NZ337446A (en) | 1997-02-25 | 2001-02-23 | Corixa Corp | Immunogenic portions of a prostate protein and their use in immunotherapy of prostate cancer and methods for their use |
WO1998037418A2 (en) | 1997-02-25 | 1998-08-27 | Corixa Corporation | Compounds for immunodiagnosis of prostate cancer and methods for their use |
US6020478A (en) | 1997-02-28 | 2000-02-01 | Incyte Pharmaceuticals, Inc. | Human tumor-associated antigen |
EP0972029A1 (en) | 1997-03-07 | 2000-01-19 | Human Genome Sciences, Inc. | Human secreted proteins |
WO1998045435A2 (en) | 1997-04-10 | 1998-10-15 | Genetics Institute, Inc. | SECRETED EXPRESSED SEQUENCE TAGS (sESTs) |
WO1998050567A1 (en) | 1997-05-02 | 1998-11-12 | Abbott Laboratories | Reagents and methods useful for detecting diseases of the prostate |
US6222029B1 (en) | 1997-08-01 | 2001-04-24 | Genset | 5′ ESTs for secreted proteins expressed in brain |
JP2001512013A (ja) | 1997-08-01 | 2001-08-21 | ジェンセット | 前立腺に発現される分泌タンパク質の5’est |
DK1000146T3 (da) | 1997-08-01 | 2007-01-08 | Serono Genetics Inst Sa | 5' EST'er for non-vævsspecifikke secernerede proteiner |
JP2001523453A (ja) | 1997-11-13 | 2001-11-27 | ジェンセット | 分泌タンパク質の伸長cDNA |
CA2311572A1 (en) | 1997-12-17 | 1999-06-24 | Genset S.A. | Extended cdnas for secreted proteins |
DE19805633A1 (de) | 1998-02-12 | 1999-08-19 | Basf Ag | Neue Serinprotease aus der Prostata |
-
1998
- 1998-02-09 US US09/020,956 patent/US6261562B1/en not_active Expired - Fee Related
- 1998-02-25 KR KR1019997007766A patent/KR100572817B1/ko not_active IP Right Cessation
- 1998-02-25 EP EP10179294.3A patent/EP2298877B1/en not_active Expired - Lifetime
- 1998-02-25 EP EP09167933A patent/EP2143731A1/en not_active Withdrawn
- 1998-02-25 AR ARP980100838A patent/AR008727A1/es active IP Right Grant
- 1998-02-25 CO CO98010249A patent/CO4850588A1/es unknown
- 1998-02-25 CA CA2742641A patent/CA2742641A1/en not_active Abandoned
- 1998-02-25 TW TW087102742A patent/TW581808B/zh not_active IP Right Cessation
- 1998-07-08 SA SA98190265A patent/SA98190265B1/ar unknown
-
2007
- 2007-08-09 AR ARP070103521A patent/AR062300A2/es unknown
Also Published As
Publication number | Publication date |
---|---|
US6261562B1 (en) | 2001-07-17 |
EP2143731A1 (en) | 2010-01-13 |
EP2298877A1 (en) | 2011-03-23 |
CO4850588A1 (es) | 1999-10-26 |
EP2298877B1 (en) | 2014-09-24 |
TW581808B (en) | 2004-04-01 |
KR100572817B1 (ko) | 2006-04-24 |
CA2742641A1 (en) | 1998-08-27 |
SA98190265B1 (ar) | 2006-11-12 |
KR20000075699A (ko) | 2000-12-26 |
AR008727A1 (es) | 2000-02-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AR062300A2 (es) | Polipeptido que comprende una porcion inmunogenica de una proteina de prostata o su variante, molecula de adn, vector de expresion, celula huesped composicion farmaceutica, vacuna uso de dichas composiciones y vacunas para preparar medicamentos y proteina de fusion | |
BR0013542A (pt) | Moléculas b7-4 e usos para as mesmas | |
AR062867A2 (es) | Proteinas de enlace a interleuquina -18, (il- 18bp), secuencias de adn que codifican para la il -18 bp, secuencias de adnc, un vehiculo de expresion replicable, celula huesped, un proceso para su produccion y aislacion, anticuerpos, composiciones farmaceuticas, el uso de dichas composiciones para la | |
AR053063A2 (es) | Proteina sustancialmente purificada y composicion farmaceutica que la comprende | |
AR038568A1 (es) | Anticuerpos anti-a beta y su uso | |
CY1114265T1 (el) | Πρωτεϊνη συντηξης αλβουμινης | |
CA2281952A1 (en) | Compounds for immunotherapy of prostate cancer and methods for their use | |
CY1117401T1 (el) | Πρωτεϊνες συντηξης αλβουμινης | |
AR006250A1 (es) | Compuestos y metodos para la inmunoterapia e inmunodiagnostico del cancer prostatico | |
BR9711123A (pt) | Quimeras de leucotoxina-gnrh | |
AR050095A1 (es) | Secuencias de subinidades pequenas de sintasa acetohidroxiacida de monocotiledoneas y metodos de uso. | |
DK1133565T3 (da) | Generering af specifikke bindingspartnere til (poly)peptider, som der kodes for af genomiske DNA-fragmenter eller EST'er | |
IL133056A (en) | Polypeptide containing an immunogenic portion of an m. tuberculosis antigen, a variant thereof and pharmaceutical compositions containing same | |
ATE500323T1 (de) | Subtilisin-variante | |
DK1265914T3 (da) | WNT-1-relaterede polypeptider og nukleinsyrer, der koder for samme | |
RU95115239A (ru) | Аналог эритропоэтина | |
AR067658A2 (es) | Un polipeptido inmunogenico, un polinucleotido que lo codifica , las composiciones farmaceuticas que contienen dichos polipeptidos y polinucleotido, los vectores de xpresion, vacunas, un metodo para la preparacion de dicho polipeptido y una celula huesped aislada que expresa dicho polipeptido | |
DK1349944T3 (da) | Latensassocieret peptid af TGF-beta til at bibringe farmaceutisk aktive proteiner latens | |
BR0009393A (pt) | Polipeptìdeo, sequência de ácido nucleico isolada, construção de ácido nucleico, vetor de expressão recombinante, célula hospedeira recombinante, método para a produção do polipeptìdeo, uso de um polipeptìdeo, e, composição detergente | |
WO2021198706A3 (en) | Coronavirus vaccines | |
SE9402089D0 (sv) | Recombinant allergen, fragments thereof, corresponding recombinant DNA molecules, vectors and hosts containing the DNA molecules, diagnostic and therapeutic uses of said allergens and fragments | |
AR035077A1 (es) | Polipeptidos de neublastina variante, proteinas de fusion, acidos nucleicos, vectores, celulas hospedadoras, metodos para producir dichos polipeptidos, dimeros, conjugados, composiciones farmaceuticas y uso de dichos polipeptidos en la preparacion de medicamentos | |
PE20001287A1 (es) | Composicion farmaceutica que contiene fragmentos de adn codificador de una proteina antigenica con efecto antitumoral | |
DK0805204T3 (da) | Bitestikel - specifikt receptorprotein og anvendelse heraf | |
PE20010239A1 (es) | Gen derivado de lawsonia y polipeptidos, peptidos y proteinas de hemolisina relacionados y sus usos |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FB | Suspension of granting procedure |