CO4850588A1 - Compuestos para inmunoterapia del cancer de prostata . - Google Patents

Compuestos para inmunoterapia del cancer de prostata .

Info

Publication number
CO4850588A1
CO4850588A1 CO98010249A CO98010249A CO4850588A1 CO 4850588 A1 CO4850588 A1 CO 4850588A1 CO 98010249 A CO98010249 A CO 98010249A CO 98010249 A CO98010249 A CO 98010249A CO 4850588 A1 CO4850588 A1 CO 4850588A1
Authority
CO
Colombia
Prior art keywords
chains
polypeptide
chain
nucleotide
protein
Prior art date
Application number
CO98010249A
Other languages
English (en)
Inventor
Jiangchun Xu
Original Assignee
Corixa Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corixa Corp filed Critical Corixa Corp
Publication of CO4850588A1 publication Critical patent/CO4850588A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Un polipéptido que comprende la porción inmunogénica de unaproteína de prostata, o una variante de la misma, en donde dicha proteína comprende una cadena de aminoácido, codificada por una molécula de DNA que tiene una cadena seleccionada entre el grupo que consiste de las cadenas de nucleótidos que se enumeran en las SEQ ID Nos. 2, 3, 8, 29, 41-45, 47, 52, 54-65, 7O, 73-74, 79, 81, 87, 90, 92, 93, 97, 103, 104, 107, 109-111, 115-160, 171, 173, 175 y 177, los complementos de dichas cadenas de nucleótidos y las variantes de las mismas cadenas. Una molécula de DNA que comprende una cadena de nucleótidos que codifica el polipéptido de la reivindicación 1. 1Un compuesto farmacológico para el tratamiento del cáncer de próstata, que comprende un polipéptido y un portador que no presente rechazo fisiológico, donde el polipéptido comprende una porción inmunogénica de una proteína de próstata o de una variante de la misma, donde dicha proteína comprende una cadena de aminoácido codificada por una molécula de DNA que tiene una cadena seleccionada entre el grupo que consiste de las cadenas de nucleótidos que se enumeran en las SEQ ID Nos: 5-7, 30, 40, 46, 53, 66-69, 71, 72, 75,-78, 80, 82-86, 88, 89,91, 94-96, 98-102, 105, 106 y 161-170, los complementos de dichas cadenas de nucleótidos y las variantes de las mismas cadenas. 1Una vacuna para el tratamiento del cáncer de próstata, que comprende un polipéptido y un acrecentador no específico de la respuesta inmunológica, donde dicho polipéptido comprende una porción inmunogénica de una proteína de próstata o una variante de la misma, donde dicha proteína comprende una cadena de aminoácido codificada por una molécula de DNA que tiene una cadena seleccionada entre el grupo que consiste de las cadenas de nucleótidos que se enumeran en las SEQ ID Nos: 5-7, 30, 40, 46, 53, 66-69, 71, 72, 75, 78, 80, 82-86, 88, 89, 91, 94-96, 98-102, 105, 106 y 161-170, los complementos de dichas cadenas de nucleótidos y las variantes de las mismas cadenas.
CO98010249A 1997-02-25 1998-02-25 Compuestos para inmunoterapia del cancer de prostata . CO4850588A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US80609997A 1997-02-25 1997-02-25
US90480497A 1997-08-01 1997-08-01
US09/020,956 US6261562B1 (en) 1997-02-25 1998-02-09 Compounds for immunotherapy of prostate cancer and methods for their use

Publications (1)

Publication Number Publication Date
CO4850588A1 true CO4850588A1 (es) 1999-10-26

Family

ID=27122845

Family Applications (1)

Application Number Title Priority Date Filing Date
CO98010249A CO4850588A1 (es) 1997-02-25 1998-02-25 Compuestos para inmunoterapia del cancer de prostata .

Country Status (8)

Country Link
US (1) US6261562B1 (es)
EP (2) EP2143731A1 (es)
KR (1) KR100572817B1 (es)
AR (2) AR008727A1 (es)
CA (1) CA2742641A1 (es)
CO (1) CO4850588A1 (es)
SA (1) SA98190265B1 (es)
TW (1) TW581808B (es)

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Also Published As

Publication number Publication date
EP2298877A1 (en) 2011-03-23
EP2143731A1 (en) 2010-01-13
EP2298877B1 (en) 2014-09-24
US6261562B1 (en) 2001-07-17
AR008727A1 (es) 2000-02-09
KR100572817B1 (ko) 2006-04-24
KR20000075699A (ko) 2000-12-26
TW581808B (en) 2004-04-01
SA98190265B1 (ar) 2006-11-12
AR062300A2 (es) 2008-10-29
CA2742641A1 (en) 1998-08-27

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