PE20010237A1 - GEN DERIVADO DE LAWSONIA Y POLIPEPTIDOS OmpH, PEPTIDOS Y PROTEINAS RELACIONADOS Y SUS USOS - Google Patents
GEN DERIVADO DE LAWSONIA Y POLIPEPTIDOS OmpH, PEPTIDOS Y PROTEINAS RELACIONADOS Y SUS USOSInfo
- Publication number
- PE20010237A1 PE20010237A1 PE2000000448A PE0004482000A PE20010237A1 PE 20010237 A1 PE20010237 A1 PE 20010237A1 PE 2000000448 A PE2000000448 A PE 2000000448A PE 0004482000 A PE0004482000 A PE 0004482000A PE 20010237 A1 PE20010237 A1 PE 20010237A1
- Authority
- PE
- Peru
- Prior art keywords
- polypeptide
- lawsonia
- omph
- coded
- refers
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 11
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 9
- 229920001184 polypeptide Polymers 0.000 title abstract 8
- 241001469654 Lawsonia <weevil> Species 0.000 title abstract 5
- 108090000623 proteins and genes Proteins 0.000 title abstract 4
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 3
- 241001148567 Lawsonia intracellularis Species 0.000 abstract 2
- 230000002163 immunogen Effects 0.000 abstract 2
- 229960005486 vaccine Drugs 0.000 abstract 2
- 108010006464 Hemolysin Proteins Proteins 0.000 abstract 1
- 108010062010 N-Acetylmuramoyl-L-alanine Amidase Proteins 0.000 abstract 1
- 102000015636 Oligopeptides Human genes 0.000 abstract 1
- 108010038807 Oligopeptides Proteins 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 239000003228 hemolysin Substances 0.000 abstract 1
- 230000004727 humoral immunity Effects 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000016784 immunoglobulin production Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 208000028774 intestinal disease Diseases 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 239000013612 plasmid Substances 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/205—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Campylobacter (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
SE REFIERE A UN POLIPEPTIDO INMUNOGENICO AISLADO O RECOMBINANTE QUE COMPRENDE, IMITA O REACCIONA CON UN EPITOPE DE CELULA B O CELULA T DE UN POLIPEPTIDO DE LAWSONIA SPP. OmpH. DE PREFERENCIA LAWSONIA INTRACELLULARIS; CAPAZ DE LOGRAR LA PRODUCCION DE ANTICUERPOS, CONFERIR UNA RESPUESTA INMUNE PROTECTORA O INDUCIR INMUNIDAD HUMORAL CONTRA LAWSONIA SPP CUANDO SE ADMINISTRA A UN AVE O PORCINO; SE SELECCIONA DE: a)UN PEPTIDO, OLIGOPEPTIDO, POLIPEPTIDO QUE COMPRENDE UNA SECUENCIA DE AMINOACIDOS CON 70% DE IDENTIDAD DE LA SEC ID NO:1, DE 186 AMINOACIDOS O LA SECUENCIA DE AMINOACIDOS CODIFICADA POR LA SECUENCIA DE NUCLEOTIDOS QUE CODIFICA EL OmpH DE pALK13(ATCC 207196); b)UN HOMOLOGO, ANALOGO, O DERIVADO QUE IMITA UN EPITOPE DE CELULA B O DE CELULA T DE UN POLIPEPTIDO DE LAWSONIA SPP. OmpH. SE REFIERE TAMBIEN A UNA VACUNA QUE COMPRENDE ADEMAS UN SEGUNDO COMPONENTE INMUNOGENICO QUE COMPRENDE UN PEPTIDO, POLIPEPTIDO O PROTEINA DE L. INTRACELLULARIS ANTIGENICO TAL COMO SodC, FlgE, HEMOLISINA, AUTOLISINA. TAMBIEN SE REFIERE A UN VECTOR PARA LA VACUNA, UNA MOLECULA DE ACIDO NUCLEICO QUE CODIFICA EL POLIPEPTIDO; UN PLASMIDO pALK13. EL POLIPEPTIDO ES CODIFICADO POR UN GEN DERIVADO DE LAWSONIA SPP Y PUEDE SER UTIL PARA EL TRATAMIENTO DE ENFERMEDADES INTESTINALES
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13398699P | 1999-05-13 | 1999-05-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20010237A1 true PE20010237A1 (es) | 2001-02-28 |
Family
ID=22461241
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2000000448A PE20010237A1 (es) | 1999-05-13 | 2000-05-12 | GEN DERIVADO DE LAWSONIA Y POLIPEPTIDOS OmpH, PEPTIDOS Y PROTEINAS RELACIONADOS Y SUS USOS |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20060018920A1 (es) |
| EP (1) | EP1183268A4 (es) |
| JP (1) | JP2003521881A (es) |
| AU (2) | AU767390B2 (es) |
| BR (1) | BR0011290A (es) |
| CA (1) | CA2372102A1 (es) |
| MX (1) | MXPA01011570A (es) |
| NZ (1) | NZ515330A (es) |
| PE (1) | PE20010237A1 (es) |
| WO (1) | WO2000069905A1 (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6605696B1 (en) | 1999-10-22 | 2003-08-12 | Pfizer, Inc. | Lawsonia intracellularis proteins, and related methods and materials |
| JP2004529854A (ja) * | 2000-09-29 | 2004-09-30 | アリゾナ・ボード・オブ・リージエンツ・オン・ビハーフ・オブ・ザ・ユニバーシテイー・オブ・アリゾナ | 増殖性回腸炎のための改善されたワクチン及びその作製と使用の方法 |
| EP1219711B1 (en) | 2000-12-20 | 2006-06-14 | Intervet International BV | Lawsonia intracellularis vaccine |
| FR2844514B1 (fr) * | 2002-09-16 | 2007-10-19 | Neovacs | Produit immunogene stable comprenant des heterocomplexes antigeniques, compositions les contenant et procede de preparation |
| CN101124241A (zh) * | 2003-12-09 | 2008-02-13 | 英特威国际有限公司 | 细胞内劳索尼亚菌26kD亚单位疫苗 |
| US8834891B2 (en) | 2005-03-14 | 2014-09-16 | Boehringer Ingelheim Vetmedica, Inc. | Immunogenic compositions comprising Lawsonia intracellularis |
| US8398994B2 (en) | 2005-07-15 | 2013-03-19 | Boehringer Ingelheim Vetmedica, Inc. | Lawsonia vaccine and methods of use thereof |
| EP2101815A4 (en) | 2006-12-11 | 2010-10-06 | Boehringer Ingelheim Vetmed | EFFICIENT PROCESS FOR THE TREATMENT OF PORCINE CIRCOVIRUS AND LAWSONIA INTRACELLULARIS INFECTIONS |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5885823A (en) * | 1995-06-05 | 1999-03-23 | Nobl Laboratories, Inc. | Lawsonia intracellularis cultivation, anti-Lawsonia intracellularis vaccines and diagnostic agents |
| WO1997020050A1 (en) * | 1995-11-30 | 1997-06-05 | Daratech Pty. Ltd. | Therapeutic and diagnostic compositions |
-
2000
- 2000-05-11 AU AU43860/00A patent/AU767390B2/en not_active Ceased
- 2000-05-11 MX MXPA01011570A patent/MXPA01011570A/es unknown
- 2000-05-11 EP EP00924977A patent/EP1183268A4/en not_active Withdrawn
- 2000-05-11 NZ NZ515330A patent/NZ515330A/xx unknown
- 2000-05-11 BR BR0011290-9A patent/BR0011290A/pt not_active IP Right Cessation
- 2000-05-11 WO PCT/AU2000/000438 patent/WO2000069905A1/en not_active Application Discontinuation
- 2000-05-11 JP JP2000618321A patent/JP2003521881A/ja active Pending
- 2000-05-11 CA CA002372102A patent/CA2372102A1/en not_active Abandoned
- 2000-05-12 PE PE2000000448A patent/PE20010237A1/es not_active Application Discontinuation
-
2004
- 2004-02-05 AU AU2004200487A patent/AU2004200487A1/en not_active Abandoned
-
2005
- 2005-08-30 US US11/215,658 patent/US20060018920A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA01011570A (es) | 2003-08-20 |
| EP1183268A4 (en) | 2003-01-02 |
| EP1183268A1 (en) | 2002-03-06 |
| AU767390B2 (en) | 2003-11-06 |
| WO2000069905A1 (en) | 2000-11-23 |
| CA2372102A1 (en) | 2000-11-23 |
| AU4386000A (en) | 2000-12-05 |
| BR0011290A (pt) | 2002-05-21 |
| US20060018920A1 (en) | 2006-01-26 |
| NZ515330A (en) | 2003-04-29 |
| JP2003521881A (ja) | 2003-07-22 |
| AU2004200487A1 (en) | 2004-03-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |