PE20010237A1 - GEN DERIVADO DE LAWSONIA Y POLIPEPTIDOS OmpH, PEPTIDOS Y PROTEINAS RELACIONADOS Y SUS USOS - Google Patents
GEN DERIVADO DE LAWSONIA Y POLIPEPTIDOS OmpH, PEPTIDOS Y PROTEINAS RELACIONADOS Y SUS USOSInfo
- Publication number
- PE20010237A1 PE20010237A1 PE2000000448A PE0004482000A PE20010237A1 PE 20010237 A1 PE20010237 A1 PE 20010237A1 PE 2000000448 A PE2000000448 A PE 2000000448A PE 0004482000 A PE0004482000 A PE 0004482000A PE 20010237 A1 PE20010237 A1 PE 20010237A1
- Authority
- PE
- Peru
- Prior art keywords
- polypeptide
- lawsonia
- omph
- coded
- refers
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 11
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 9
- 229920001184 polypeptide Polymers 0.000 title abstract 8
- 241001469654 Lawsonia <weevil> Species 0.000 title abstract 5
- 108090000623 proteins and genes Proteins 0.000 title abstract 4
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 3
- 241001148567 Lawsonia intracellularis Species 0.000 abstract 2
- 230000002163 immunogen Effects 0.000 abstract 2
- 229960005486 vaccine Drugs 0.000 abstract 2
- 108010006464 Hemolysin Proteins Proteins 0.000 abstract 1
- 108010062010 N-Acetylmuramoyl-L-alanine Amidase Proteins 0.000 abstract 1
- 102000015636 Oligopeptides Human genes 0.000 abstract 1
- 108010038807 Oligopeptides Proteins 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 239000003228 hemolysin Substances 0.000 abstract 1
- 230000004727 humoral immunity Effects 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000016784 immunoglobulin production Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 208000028774 intestinal disease Diseases 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 239000013612 plasmid Substances 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/205—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Campylobacter (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
SE REFIERE A UN POLIPEPTIDO INMUNOGENICO AISLADO O RECOMBINANTE QUE COMPRENDE, IMITA O REACCIONA CON UN EPITOPE DE CELULA B O CELULA T DE UN POLIPEPTIDO DE LAWSONIA SPP. OmpH. DE PREFERENCIA LAWSONIA INTRACELLULARIS; CAPAZ DE LOGRAR LA PRODUCCION DE ANTICUERPOS, CONFERIR UNA RESPUESTA INMUNE PROTECTORA O INDUCIR INMUNIDAD HUMORAL CONTRA LAWSONIA SPP CUANDO SE ADMINISTRA A UN AVE O PORCINO; SE SELECCIONA DE: a)UN PEPTIDO, OLIGOPEPTIDO, POLIPEPTIDO QUE COMPRENDE UNA SECUENCIA DE AMINOACIDOS CON 70% DE IDENTIDAD DE LA SEC ID NO:1, DE 186 AMINOACIDOS O LA SECUENCIA DE AMINOACIDOS CODIFICADA POR LA SECUENCIA DE NUCLEOTIDOS QUE CODIFICA EL OmpH DE pALK13(ATCC 207196); b)UN HOMOLOGO, ANALOGO, O DERIVADO QUE IMITA UN EPITOPE DE CELULA B O DE CELULA T DE UN POLIPEPTIDO DE LAWSONIA SPP. OmpH. SE REFIERE TAMBIEN A UNA VACUNA QUE COMPRENDE ADEMAS UN SEGUNDO COMPONENTE INMUNOGENICO QUE COMPRENDE UN PEPTIDO, POLIPEPTIDO O PROTEINA DE L. INTRACELLULARIS ANTIGENICO TAL COMO SodC, FlgE, HEMOLISINA, AUTOLISINA. TAMBIEN SE REFIERE A UN VECTOR PARA LA VACUNA, UNA MOLECULA DE ACIDO NUCLEICO QUE CODIFICA EL POLIPEPTIDO; UN PLASMIDO pALK13. EL POLIPEPTIDO ES CODIFICADO POR UN GEN DERIVADO DE LAWSONIA SPP Y PUEDE SER UTIL PARA EL TRATAMIENTO DE ENFERMEDADES INTESTINALES
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13398699P | 1999-05-13 | 1999-05-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20010237A1 true PE20010237A1 (es) | 2001-02-28 |
Family
ID=22461241
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2000000448A PE20010237A1 (es) | 1999-05-13 | 2000-05-12 | GEN DERIVADO DE LAWSONIA Y POLIPEPTIDOS OmpH, PEPTIDOS Y PROTEINAS RELACIONADOS Y SUS USOS |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20060018920A1 (es) |
| EP (1) | EP1183268A4 (es) |
| JP (1) | JP2003521881A (es) |
| AU (2) | AU767390B2 (es) |
| BR (1) | BR0011290A (es) |
| CA (1) | CA2372102A1 (es) |
| MX (1) | MXPA01011570A (es) |
| NZ (1) | NZ515330A (es) |
| PE (1) | PE20010237A1 (es) |
| WO (1) | WO2000069905A1 (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6605696B1 (en) | 1999-10-22 | 2003-08-12 | Pfizer, Inc. | Lawsonia intracellularis proteins, and related methods and materials |
| AU2001293151B8 (en) * | 2000-09-29 | 2006-01-12 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Improved Vaccines for Proliferative Ileitis and Methods of Making and Using the Same |
| DE60120621T2 (de) | 2000-12-20 | 2006-12-14 | Intervet International B. V. | Lawsonia intracellularis Impfstoff |
| FR2844514B1 (fr) * | 2002-09-16 | 2007-10-19 | Neovacs | Produit immunogene stable comprenant des heterocomplexes antigeniques, compositions les contenant et procede de preparation |
| CA2548750A1 (en) * | 2003-12-09 | 2005-06-23 | Intervet International B.V. | Lawsonia intracellularis 26 kd subunit vaccine |
| US8834891B2 (en) | 2005-03-14 | 2014-09-16 | Boehringer Ingelheim Vetmedica, Inc. | Immunogenic compositions comprising Lawsonia intracellularis |
| US8398994B2 (en) | 2005-07-15 | 2013-03-19 | Boehringer Ingelheim Vetmedica, Inc. | Lawsonia vaccine and methods of use thereof |
| WO2008073464A2 (en) | 2006-12-11 | 2008-06-19 | Boehringer Ingelheim Vetmedica, Inc. | Effective method of treatment of porcine circovirus and lawsonia intracellularis infections |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5885823A (en) * | 1995-06-05 | 1999-03-23 | Nobl Laboratories, Inc. | Lawsonia intracellularis cultivation, anti-Lawsonia intracellularis vaccines and diagnostic agents |
| US7022328B1 (en) * | 1995-11-30 | 2006-04-04 | Australian Pork Limited | Therapeutic and diagnostic compositions |
-
2000
- 2000-05-11 JP JP2000618321A patent/JP2003521881A/ja active Pending
- 2000-05-11 WO PCT/AU2000/000438 patent/WO2000069905A1/en not_active Application Discontinuation
- 2000-05-11 MX MXPA01011570A patent/MXPA01011570A/es unknown
- 2000-05-11 NZ NZ515330A patent/NZ515330A/xx unknown
- 2000-05-11 BR BR0011290-9A patent/BR0011290A/pt not_active IP Right Cessation
- 2000-05-11 AU AU43860/00A patent/AU767390B2/en not_active Ceased
- 2000-05-11 EP EP00924977A patent/EP1183268A4/en not_active Withdrawn
- 2000-05-11 CA CA002372102A patent/CA2372102A1/en not_active Abandoned
- 2000-05-12 PE PE2000000448A patent/PE20010237A1/es not_active Application Discontinuation
-
2004
- 2004-02-05 AU AU2004200487A patent/AU2004200487A1/en not_active Abandoned
-
2005
- 2005-08-30 US US11/215,658 patent/US20060018920A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20060018920A1 (en) | 2006-01-26 |
| BR0011290A (pt) | 2002-05-21 |
| NZ515330A (en) | 2003-04-29 |
| WO2000069905A1 (en) | 2000-11-23 |
| AU4386000A (en) | 2000-12-05 |
| AU767390B2 (en) | 2003-11-06 |
| AU2004200487A1 (en) | 2004-03-04 |
| EP1183268A1 (en) | 2002-03-06 |
| EP1183268A4 (en) | 2003-01-02 |
| JP2003521881A (ja) | 2003-07-22 |
| CA2372102A1 (en) | 2000-11-23 |
| MXPA01011570A (es) | 2003-08-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |