BR0016129A - Molécula de ácido nucléico, vetor recombinante, polipeptìdeo, racemase de aminoácido eucariótica, anticorpos, célula hospedeira, métodos para produzir polipeptìdeo, para detectar um parasita e uma proteìna eucariótica, para triar moléculas ativas, para detectar e quantificar a presença ou a ausência de uma sequência, para inibir uma proteìna eucariótica, para produzir uma racemase de aminoácido recombinante eucariótica e d-aminoácio e para prevenir ou inibir infecção, plasmìdeo, complexo imunológico, kit para detectar um parasita, fragmento de um polinucleotìdeo, proteìna eucariótica, processos para preparar uma proteìna eucariótica purificada, para detectar uma infecção e para infecção e para triar uma molécula, composição imunizadora, composição de vacina, qualquer modificação molecular do gene ou de um fragmento do gene, uso de qualquer modificação molecular ou bioquìmica da atividade enzimática da racemase, e, qualquer molécula ou composto - Google Patents
Molécula de ácido nucléico, vetor recombinante, polipeptìdeo, racemase de aminoácido eucariótica, anticorpos, célula hospedeira, métodos para produzir polipeptìdeo, para detectar um parasita e uma proteìna eucariótica, para triar moléculas ativas, para detectar e quantificar a presença ou a ausência de uma sequência, para inibir uma proteìna eucariótica, para produzir uma racemase de aminoácido recombinante eucariótica e d-aminoácio e para prevenir ou inibir infecção, plasmìdeo, complexo imunológico, kit para detectar um parasita, fragmento de um polinucleotìdeo, proteìna eucariótica, processos para preparar uma proteìna eucariótica purificada, para detectar uma infecção e para infecção e para triar uma molécula, composição imunizadora, composição de vacina, qualquer modificação molecular do gene ou de um fragmento do gene, uso de qualquer modificação molecular ou bioquìmica da atividade enzimática da racemase, e, qualquer molécula ou compostoInfo
- Publication number
- BR0016129A BR0016129A BR0016129-2A BR0016129A BR0016129A BR 0016129 A BR0016129 A BR 0016129A BR 0016129 A BR0016129 A BR 0016129A BR 0016129 A BR0016129 A BR 0016129A
- Authority
- BR
- Brazil
- Prior art keywords
- detect
- eukaryotic
- infection
- molecule
- eukaryotic protein
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 10
- 208000015181 infectious disease Diseases 0.000 title abstract 6
- 102000004169 proteins and genes Human genes 0.000 title abstract 6
- 244000045947 parasite Species 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 4
- 230000004048 modification Effects 0.000 title abstract 4
- 238000012986 modification Methods 0.000 title abstract 4
- 102000006534 Amino Acid Isomerases Human genes 0.000 title abstract 3
- 108010008830 Amino Acid Isomerases Proteins 0.000 title abstract 3
- 239000012634 fragment Substances 0.000 title abstract 3
- 229920001184 polypeptide Polymers 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 102000004879 Racemases and epimerases Human genes 0.000 title abstract 2
- 108090001066 Racemases and epimerases Proteins 0.000 title abstract 2
- 230000003053 immunization Effects 0.000 title abstract 2
- 102000039446 nucleic acids Human genes 0.000 title abstract 2
- 108020004707 nucleic acids Proteins 0.000 title abstract 2
- 150000007523 nucleic acids Chemical class 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 230000002255 enzymatic effect Effects 0.000 title 1
- 239000013612 plasmid Substances 0.000 title 1
- 102000040430 polynucleotide Human genes 0.000 title 1
- 108091033319 polynucleotide Proteins 0.000 title 1
- 239000002157 polynucleotide Substances 0.000 title 1
- 241000700605 Viruses Species 0.000 abstract 3
- 230000001225 therapeutic effect Effects 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000001900 immune effect Effects 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000003226 mitogen Substances 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/6893—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for protozoa
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56905—Protozoa
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Analytical Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Virology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Toxicology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pathology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16863199P | 1999-12-03 | 1999-12-03 | |
US22020700P | 2000-07-24 | 2000-07-24 | |
US22111700P | 2000-07-27 | 2000-07-27 | |
PCT/IB2000/002008 WO2001040449A2 (en) | 1999-12-03 | 2000-12-04 | Cloning of a gene encoding an amino acid racemase from trypanosoma cruzi, and uses thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
BR0016129A true BR0016129A (pt) | 2002-08-20 |
BRPI0016129B1 BRPI0016129B1 (pt) | 2016-07-05 |
Family
ID=27389546
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0016129A BRPI0016129B1 (pt) | 1999-12-03 | 2000-12-04 | microorganismo transgênico, plasmídeo, kits para detectar um parasita, composição de vacina contra infecção por t. cruzi, métodos para produzir polipeptídeo prolina racemase de t. cruzi (tc45) e para detectar um parasita em uma amostra biológica, e, processos para preparar uma proteína eucariótica purificada com atividade de racemase e para detectar uma infecção por t. cruzi. |
Country Status (6)
Country | Link |
---|---|
US (6) | US6713617B2 (pt) |
EP (1) | EP1240315B1 (pt) |
AU (1) | AU2212701A (pt) |
BR (1) | BRPI0016129B1 (pt) |
MX (1) | MXPA02005506A (pt) |
WO (1) | WO2001040449A2 (pt) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2768747B1 (fr) * | 1997-09-19 | 2000-12-01 | Pasteur Institut | Acides nucleiques, cellules recombinantes, et procede de preparation de compositions immunogenes |
US6713617B2 (en) * | 1999-12-03 | 2004-03-30 | Institut Pasteur | Cloning, sequencing and expression of a gene encoding an eukaryotic amino acid racemase, and diagnostic, therapeutic, and vaccination applications of parasite and viral mitogens |
EP1592788A2 (en) * | 2003-02-11 | 2005-11-09 | Institut Pasteur | Identification and characterization of racemases, definition of protein signatures, and a test for detecting d-amino acid and for screening molecules capable of inhibiting the activity of racemase, especially proline racemase |
US7585656B2 (en) | 2003-02-11 | 2009-09-08 | Institute Pasteur | Crystallographic structure of TcPRACA and uses therefor |
US20050155779A1 (en) * | 2003-04-08 | 2005-07-21 | Xingwu Wang | Coated substrate assembly |
US20050119725A1 (en) * | 2003-04-08 | 2005-06-02 | Xingwu Wang | Energetically controlled delivery of biologically active material from an implanted medical device |
ATE490269T1 (de) | 2003-05-30 | 2010-12-15 | Pasteur Institut | Kristallstruktur der trypanosoma cruzi proline racemase (tcpraca) und verwendung davon |
US20060118758A1 (en) * | 2004-09-15 | 2006-06-08 | Xingwu Wang | Material to enable magnetic resonance imaging of implantable medical devices |
EP1814995A2 (en) * | 2004-10-27 | 2007-08-08 | North Carolina State University | Lactobacillus acidophilus nucleic acids and uses thereof |
US20090156431A1 (en) * | 2007-12-12 | 2009-06-18 | Si Lok | Methods for Nucleic Acid Mapping and Identification of Fine Structural Variations in Nucleic Acids |
WO2010000849A2 (en) * | 2008-07-04 | 2010-01-07 | Institut De Recherche Pour Le Developpement (I.R.D.) | A method for the screening of conserved secreted proteins |
RU2490634C1 (ru) * | 2012-01-27 | 2013-08-20 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Тюменская государственная сельскохозяйственная академия" (ФГБОУ ВПО ТГСХА) | Способ диагностики хламидийной инфекции у хряков-производителей |
CN114854728B (zh) * | 2022-05-12 | 2023-11-24 | 云南师范大学 | 一种脯氨酸消旋酶及其制备和应用 |
CN118252943B (zh) * | 2023-10-25 | 2024-09-20 | 常州市智态生创科技有限公司 | 一种短肽偶联药物及其制备方法和应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0696323A1 (de) * | 1993-04-23 | 1996-02-14 | Novartis AG | Rekombinante alanin racemase und gadph aus tolypocladium niveum |
JP3473985B2 (ja) * | 1994-04-26 | 2003-12-08 | 協和醗酵工業株式会社 | D−プロリンの製造法 |
US6713617B2 (en) * | 1999-12-03 | 2004-03-30 | Institut Pasteur | Cloning, sequencing and expression of a gene encoding an eukaryotic amino acid racemase, and diagnostic, therapeutic, and vaccination applications of parasite and viral mitogens |
JP2005117918A (ja) | 2003-10-14 | 2005-05-12 | Glycomedics Inc | 新規糖鎖プライマー |
-
2000
- 2000-11-30 US US09/725,945 patent/US6713617B2/en not_active Expired - Lifetime
- 2000-12-04 AU AU22127/01A patent/AU2212701A/en not_active Abandoned
- 2000-12-04 EP EP00985729A patent/EP1240315B1/en not_active Expired - Lifetime
- 2000-12-04 WO PCT/IB2000/002008 patent/WO2001040449A2/en active Application Filing
- 2000-12-04 BR BRPI0016129A patent/BRPI0016129B1/pt not_active IP Right Cessation
-
2002
- 2002-06-03 MX MXPA02005506A patent/MXPA02005506A/es active IP Right Grant
-
2003
- 2003-09-16 US US10/662,437 patent/US20050090656A1/en not_active Abandoned
- 2003-09-16 US US10/662,425 patent/US20050130166A1/en not_active Abandoned
-
2006
- 2006-03-17 US US11/378,706 patent/US8168770B2/en not_active Expired - Fee Related
- 2006-03-17 US US11/384,144 patent/US7851603B2/en not_active Expired - Fee Related
- 2006-03-24 US US11/388,474 patent/US7732563B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20060292598A1 (en) | 2006-12-28 |
US7851603B2 (en) | 2010-12-14 |
AU2212701A (en) | 2001-06-12 |
US20050090656A1 (en) | 2005-04-28 |
WO2001040449A9 (en) | 2002-11-07 |
US8168770B2 (en) | 2012-05-01 |
US20040018206A1 (en) | 2004-01-29 |
US7732563B2 (en) | 2010-06-08 |
US20060252921A1 (en) | 2006-11-09 |
US6713617B2 (en) | 2004-03-30 |
US20050130166A1 (en) | 2005-06-16 |
MXPA02005506A (es) | 2004-09-10 |
WO2001040449A2 (en) | 2001-06-07 |
BRPI0016129B1 (pt) | 2016-07-05 |
EP1240315A2 (en) | 2002-09-18 |
EP1240315B1 (en) | 2012-06-20 |
WO2001040449A3 (en) | 2002-01-10 |
US20060292596A1 (en) | 2006-12-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
RU2468080C2 (ru) | Новый класс терапевтических белковых молекул | |
KR100466407B1 (ko) | 보툴리누스 신경독소를 함유하는 약학적 조성물 | |
BR0016129A (pt) | Molécula de ácido nucléico, vetor recombinante, polipeptìdeo, racemase de aminoácido eucariótica, anticorpos, célula hospedeira, métodos para produzir polipeptìdeo, para detectar um parasita e uma proteìna eucariótica, para triar moléculas ativas, para detectar e quantificar a presença ou a ausência de uma sequência, para inibir uma proteìna eucariótica, para produzir uma racemase de aminoácido recombinante eucariótica e d-aminoácio e para prevenir ou inibir infecção, plasmìdeo, complexo imunológico, kit para detectar um parasita, fragmento de um polinucleotìdeo, proteìna eucariótica, processos para preparar uma proteìna eucariótica purificada, para detectar uma infecção e para infecção e para triar uma molécula, composição imunizadora, composição de vacina, qualquer modificação molecular do gene ou de um fragmento do gene, uso de qualquer modificação molecular ou bioquìmica da atividade enzimática da racemase, e, qualquer molécula ou composto | |
BR9814276A (pt) | Antìgenos de superfìcie | |
US6692746B1 (en) | Tumor killing effects of enterotoxins, superantigens, and related compounds | |
BR9809445A (pt) | Polipeptìdeo compreendendo uma porção imunogênica de um antìgeno de m. tubercolosis, molécula de dna, vetor de expressão, célula hospedeira, composição farmacêutica, vacina, proteìna de fusão, processos para indução de imunidade protetora em um paciente, processo de detecção de tuberculose em um paciente,e , kit de diagnóstico. | |
BR9712518A (pt) | Polipeptìdeo, molécula de dna, vetor de expressão, célula hospedeira, composição farmacêutica, vacina, proteìna de fusão, processo para detectar tuberculose em um paciente, e, kit diagnóstico | |
SE0103754L (sv) | Peptider från apolipoprotein B, användning därav immunisering, diagnosmetod eller terapeutisk behandling av ischemiska kardiovaskulära sjukdomar, samt farmaceutisk komposition och vaccin innehållande sådan peptid | |
JP6961061B2 (ja) | 癌治療のためのadi−peg20抗体に対する交差反応性が低減したアルギニンデイミナーゼ | |
DE69519521D1 (de) | Zusammensetzung enthaltend ein antigen exprimierendes rekombinantes virus und ein immunstimulierendes molekül exprimierendes rekombinantes virus | |
BRPI0010612B8 (pt) | vacinas | |
RU95108217A (ru) | Дефектный рекомбинантный аденовирус, линия клеток, фармацевтическая композиция | |
MA27699A1 (fr) | Vaccin contre vhc | |
EP1129717B1 (en) | Use of homologues of staphylococcal enterotoxins for cancer treatment | |
BR0211296A (pt) | Peptìdeo imunogênico derivado da proteìna g do vrs do sub-grupo a ou b, sequência de ácido nucleico, composição farmacêutica, anticorpos policlonais ou monoclonais, kit de diagnóstico, utilização de um peptìdeo imunogênico, e, conjugado | |
EP0977862B8 (en) | Ricin-like toxin variants for treatment of cancer, viral or parasitic infections | |
FR2870126A1 (fr) | Vecteur lentiviral recombinant d'expression d'une proteine de flaviviridae et ses applications comme vaccin | |
BR0205083A (pt) | Polipeptìdeo isolado, composição farmacêutica, proteìna de fusão, polinucleotìdeo isolado, vetor de expressão, célula hospedeira recombinante e métodos de produzir um polipeptìdeo, de detectar a presença da expressão de gene em uma amostra biológica, de expandir células monocìticas ou progenitores de células de monócitos e de estimular uma resposta imune em um mamìfero exposto a um antìgeno ou patógeno | |
Takagi et al. | Amino acid sequence of vitamin D‐dependent calcium‐binding protein from bovine cerebellum | |
BR0210486A (pt) | Proteìna, polipeptìdeo recombinante, sequência e vetor de ácido nucleico, célula em cultura, iniciador nucleotìdico, anticorpo purificado, composições imunogênica, de vacina e farmacêutica, processo de triagem de moléculas susceptìveis de inibir o crescimento de leishmania major, utilização de uma sonda de ácido nucleico, de um ou vários inibidores de proteìnas dissulfetos isomerases e de bacitracina ou de bacitracina de zinco, método de diagnóstico in vitro de uma infecção por um parasita responsável pela leishmaniose e kit diagnóstico para a realização do método | |
RU98112608A (ru) | Иммуногенная композиция [на основе] tlp | |
KR20110005710A (ko) | 변형된 Cpn10 및 PRR 시그널링 | |
FR2694938B1 (fr) | Nouveaux peptides, anticorps diriges contre ces peptides, anticorps anti-idiotypiques, application a titre de medicaments, compositions pharmaceutiques et kits de diagnostic les renfermant. | |
CN113185586B (zh) | SARS-CoV-2编码蛋白来源的T细胞表位多肽及其应用 | |
BRPI0410460A (pt) | antìgeno t24 para o diagnóstico imunológico da cisticercose causada por taenia solium |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] |
Free format text: O DEPOSITANTE DEVERA APRESENTAR A PETICAO DEVIDA PARA O CUMPRIMENTO DESTA EXIGENCIA EM ATE 60 (SESSENTA) DIAS, CONTADOS A PARTIR DA DATA DE PUBLICACAO NA RPI, DE ACORDO COM O ART. 34 (II) DA LPI PARA QUE SE DE INICIO AO EXAME TECNICO DO PEDIDO. |
|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 05/07/2016, OBSERVADAS AS CONDICOES LEGAIS. |
|
B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 20A ANUIDADE. |
|
B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2606 DE 15-12-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |