KR100652513B1 - 결핵의 면역치료 및 진단용 화합물과 이의 사용 방법 - Google Patents

결핵의 면역치료 및 진단용 화합물과 이의 사용 방법 Download PDF

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Publication number
KR100652513B1
KR100652513B1 KR1019997010775A KR19997010775A KR100652513B1 KR 100652513 B1 KR100652513 B1 KR 100652513B1 KR 1019997010775 A KR1019997010775 A KR 1019997010775A KR 19997010775 A KR19997010775 A KR 19997010775A KR 100652513 B1 KR100652513 B1 KR 100652513B1
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KR20010012812A (ko
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앨더슨마크알
딜론다빈씨
스케이키야시에이더블유
캠포스-네토안토니오
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코리사 코퍼레이션
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1019997010775A 1997-05-20 1998-05-20 결핵의 면역치료 및 진단용 화합물과 이의 사용 방법 Expired - Fee Related KR100652513B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US85938197A 1997-05-20 1997-05-20
US08/859,381 1997-05-20
US09/073,010 US6613881B1 (en) 1997-05-20 1998-05-05 Compounds for immunotherapy and diagnosis of tuberculosis and methods of their use
US09/073,010 1998-05-05
PCT/US1998/010407 WO1998053075A2 (en) 1997-05-20 1998-05-20 Compounds for immunotherapy and diagnosis of tuberculosis and methods of their use

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020067010257A Division KR100893118B1 (ko) 1997-05-20 1998-05-20 결핵의 면역치료 및 진단용 화합물과 이의 사용 방법

Publications (2)

Publication Number Publication Date
KR20010012812A KR20010012812A (ko) 2001-02-26
KR100652513B1 true KR100652513B1 (ko) 2006-12-01

Family

ID=26754016

Family Applications (4)

Application Number Title Priority Date Filing Date
KR1019997010775A Expired - Fee Related KR100652513B1 (ko) 1997-05-20 1998-05-20 결핵의 면역치료 및 진단용 화합물과 이의 사용 방법
KR1020087007618A Expired - Fee Related KR100924475B1 (ko) 1997-05-20 1998-05-20 결핵의 면역치료 및 진단용 화합물과 이의 사용 방법
KR1020077003582A Expired - Fee Related KR100909640B1 (ko) 1997-05-20 1998-05-20 결핵의 면역치료 및 진단용 화합물과 이의 사용 방법
KR1020067010257A Expired - Fee Related KR100893118B1 (ko) 1997-05-20 1998-05-20 결핵의 면역치료 및 진단용 화합물과 이의 사용 방법

Family Applications After (3)

Application Number Title Priority Date Filing Date
KR1020087007618A Expired - Fee Related KR100924475B1 (ko) 1997-05-20 1998-05-20 결핵의 면역치료 및 진단용 화합물과 이의 사용 방법
KR1020077003582A Expired - Fee Related KR100909640B1 (ko) 1997-05-20 1998-05-20 결핵의 면역치료 및 진단용 화합물과 이의 사용 방법
KR1020067010257A Expired - Fee Related KR100893118B1 (ko) 1997-05-20 1998-05-20 결핵의 면역치료 및 진단용 화합물과 이의 사용 방법

Country Status (20)

Country Link
US (1) US6613881B1 (enExample)
EP (4) EP2270170B1 (enExample)
JP (4) JP4162155B2 (enExample)
KR (4) KR100652513B1 (enExample)
AT (1) ATE420180T1 (enExample)
AU (1) AU742751B2 (enExample)
BR (1) BR9809445A (enExample)
CA (2) CA2290774A1 (enExample)
CZ (2) CZ300866B6 (enExample)
DE (1) DE69840449D1 (enExample)
DK (1) DK1012293T3 (enExample)
ES (1) ES2321039T3 (enExample)
HU (1) HU226520B1 (enExample)
IL (2) IL133056A0 (enExample)
NO (4) NO324880B1 (enExample)
NZ (1) NZ501310A (enExample)
PL (1) PL191121B1 (enExample)
PT (1) PT1012293E (enExample)
TR (1) TR200000115T2 (enExample)
WO (1) WO1998053075A2 (enExample)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
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US6991797B2 (en) 1993-07-02 2006-01-31 Statens Serum Institut M. tuberculosis antigens
US6458366B1 (en) 1995-09-01 2002-10-01 Corixa Corporation Compounds and methods for diagnosis of tuberculosis
US6290969B1 (en) * 1995-09-01 2001-09-18 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
US6592877B1 (en) * 1995-09-01 2003-07-15 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
US6982085B2 (en) 1997-04-02 2006-01-03 Statens Serum Institut TB diagnostic based on antigens from M. tuberculosis
US7037510B2 (en) 1997-04-18 2006-05-02 Statens Serum Institut Hybrids of M. tuberculosis antigens
ATE432348T1 (de) 1997-06-06 2009-06-15 Univ California Inhibitoren von immunstimulatorischen dna sequenz aktivität
CA2319380A1 (en) * 1997-11-10 1999-05-20 Statens Serum Institut Nucleic acid fragments and polypeptide fragments derived from m. tuberculosis
CA2348475A1 (en) * 1998-11-04 2000-05-11 Isis Innovation Limited Tuberculosis diagnostic test
US20030027774A1 (en) * 1999-03-18 2003-02-06 Ronald C. Hendrickson Tuberculosis antigens and methods of use therefor
US8143386B2 (en) * 1999-04-07 2012-03-27 Corixa Corporation Fusion proteins of mycobacterium tuberculosis antigens and their uses
EP1200466A2 (en) * 1999-07-13 2002-05-02 Statens Serum Institut Tuberculosis vaccine and diagnostics based on the mycobacterium tuberculosisesat-6 gene family
JP2003510370A (ja) 1999-10-07 2003-03-18 コリクサ コーポレイション Ｍｙｃｏｂａｃｔｅｒｉｕｍｔｕｂｅｒｃｕｌｏｓｉｓの融合タンパク質
US6316205B1 (en) 2000-01-28 2001-11-13 Genelabs Diagnostics Pte Ltd. Assay devices and methods of analyte detection
AU2001241738A1 (en) 2000-02-25 2001-09-03 Corixa Corporation Compounds and methods for diagnosis and immunotherapy of tuberculosis
WO2001079274A2 (en) * 2000-04-19 2001-10-25 Statens Serum Institut Tuberculosis antigens and methods of use thereof
EP1542732B1 (en) 2000-06-20 2009-09-16 Corixa Corporation Fusion proteins of mycobacterium tuberculosis
WO2003070187A2 (en) * 2002-02-15 2003-08-28 Corixa Corporation Fusion proteins of mycobacterium tuberculosis
US7482116B2 (en) 2002-06-07 2009-01-27 Dna Genotek Inc. Compositions and methods for obtaining nucleic acids from sputum
US20050164168A1 (en) * 2003-03-28 2005-07-28 Cullum Malford E. Method for the rapid diagnosis of infectious disease by detection and quantitation of microorganism induced cytokines
US8475735B2 (en) * 2004-11-01 2013-07-02 Uma Mahesh Babu Disposable immunodiagnostic test system
JP4838259B2 (ja) * 2004-11-16 2011-12-14 クルセル ホランド ベー ヴェー 組み換えウイルスベクターを含む多価ワクチン
EP1904848A2 (en) * 2005-04-29 2008-04-02 Fusion Antibodies Limited Assays for diagnosis of tuberculosis and uses thereof
WO2007005627A2 (en) 2005-07-01 2007-01-11 Forsyth Dental Infirmary For Children Tuberculosis antigen detection assays and vaccines
US20070081944A1 (en) * 2005-09-30 2007-04-12 Reed Steven G Iontophoresis apparatus and method for the diagnosis of tuberculosis
EP2397855A3 (en) 2006-03-14 2012-03-14 Oregon Health and Science University Methods for detecting a mycobacterium tuberculosis infection
NO2315597T3 (enExample) 2008-07-25 2018-01-20
DK2315773T3 (en) 2008-07-25 2016-12-12 Glaxosmithkline Biologicals Sa Polypeptides, polynucleotides and compositions for use in the treatment of latent tuberculosis
SI2315834T1 (sl) 2008-07-25 2018-09-28 Glaxosmithkline Biologicals S.A. Tuberkulozni Rv2386c protein, sestavki in njegove uporabe
WO2011092253A1 (en) 2010-01-27 2011-08-04 Glaxosmithkline Biologicals S.A. Modified tuberculosis antigens
GB201012072D0 (en) * 2010-07-19 2010-09-01 Sec Dep For Environment Food A Diagnostic reagents
EP2721140B1 (en) 2011-06-19 2016-11-23 Abogen, Inc. Devices, solutions and methods for sample collection
CN107430105A (zh) * 2015-02-09 2017-12-01 阿波根有限公司 用于采集相关应用、分析和诊断的样本的设备、溶液和方法

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US4751180A (en) 1985-03-28 1988-06-14 Chiron Corporation Expression using fused genes providing for protein product
US4689397A (en) 1985-08-12 1987-08-25 Scripps Clinic And Research Foundation Synthetic polypeptides for detecting mycobacterial infections
US4935233A (en) 1985-12-02 1990-06-19 G. D. Searle And Company Covalently linked polypeptide cell modulators
US4879213A (en) 1986-12-05 1989-11-07 Scripps Clinic And Research Foundation Synthetic polypeptides and antibodies related to Epstein-Barr virus early antigen-diffuse
US4976958A (en) * 1987-02-26 1990-12-11 Scripps Clinic And Research Foundation Mycobacterial recombinants and peptides
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US5330754A (en) 1992-06-29 1994-07-19 Archana Kapoor Membrane-associated immunogens of mycobacteria
JPH09510866A (ja) * 1993-12-23 1997-11-04 アグリサーチ ニュージーランド パストラル アグリカルチャー リサーチ インスティテュート，リミテッド ミコバクテリア毒力因子およびその同定のための方法
IE960132A1 (en) * 1995-03-13 1996-09-18 Astra Ab New DNA molecules
BR9610262B1 (pt) 1995-09-01 2013-11-26 Compostos e métodos para a imunoterapia e diagnose de tuberculose.
PT2154248E (pt) 1995-09-01 2012-01-16 Corixa Corp Compostos e métodos para diagnóstico de tuberculose
US6290969B1 (en) * 1995-09-01 2001-09-18 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
TR199901569T2 (xx) * 1996-10-11 2000-12-21 Corixa Corporation T�berk�lozun te�hisi i�in bile�ikler ve y�ntemler.

Also Published As

Publication number Publication date
EP2270170A1 (en) 2011-01-05
EP1012293A2 (en) 2000-06-28
JP4162155B2 (ja) 2008-10-08
BR9809445A (pt) 2000-06-13
CA2783134A1 (en) 1998-11-26
KR20060066139A (ko) 2006-06-15
JP2002514084A (ja) 2002-05-14
PL337330A1 (en) 2000-08-14
NO995689D0 (no) 1999-11-19
KR100893118B1 (ko) 2009-04-14
EP1012293B1 (en) 2009-01-07
JP4759010B2 (ja) 2011-08-31
KR100924475B1 (ko) 2009-11-03
NO20075901L (no) 2000-01-18
JP2008283961A (ja) 2008-11-27
JP4764445B2 (ja) 2011-09-07
EP2172551A3 (en) 2010-11-10
WO1998053075A2 (en) 1998-11-26
DK1012293T3 (da) 2009-05-04
PT1012293E (pt) 2009-04-08
ATE420180T1 (de) 2009-01-15
CZ300866B6 (cs) 2009-08-26
DE69840449D1 (de) 2009-02-26
EP2248900B1 (en) 2012-07-18
US6613881B1 (en) 2003-09-02
EP2172551A2 (en) 2010-04-07
AU742751B2 (en) 2002-01-10
JP2008245644A (ja) 2008-10-16
NO20075900L (no) 2000-01-18
KR20080036663A (ko) 2008-04-28
AU7690798A (en) 1998-12-11
IL133056A0 (en) 2001-03-19
CZ410099A3 (cs) 2000-05-17
NO20075902L (no) 2000-01-18
NZ501310A (en) 2001-09-28
IL133056A (en) 2010-11-30
CA2290774A1 (en) 1998-11-26
JP4759011B2 (ja) 2011-08-31
HUP0003402A2 (hu) 2000-12-28
ES2321039T3 (es) 2009-06-01
HU226520B1 (en) 2009-03-30
EP2270170B1 (en) 2013-11-06
NO324880B1 (no) 2007-12-27
CZ303194B6 (cs) 2012-05-23
HUP0003402A3 (en) 2001-03-28
TR200000115T2 (tr) 2000-11-21
NO995689L (no) 2000-01-18
PL191121B1 (pl) 2006-03-31
WO1998053075A3 (en) 1999-04-01
KR20070026886A (ko) 2007-03-08
KR20010012812A (ko) 2001-02-26
JP2008253260A (ja) 2008-10-23
KR100909640B1 (ko) 2009-07-27
EP2248900A1 (en) 2010-11-10

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