WO1997031104A3 - Candida albicans profilin gene - Google Patents

Candida albicans profilin gene

Info

Publication number
WO1997031104A3
WO1997031104A3 PCT/US1997/003798 US9703798W WO9731104A3 WO 1997031104 A3 WO1997031104 A3 WO 1997031104A3 US 9703798 W US9703798 W US 9703798W WO 9731104 A3 WO9731104 A3 WO 9731104A3
Authority
WO
WIPO (PCT)
Prior art keywords
profilin
albicans
nucleic acid
concerns
sequence
Prior art date
Application number
PCT/US1997/003798
Other languages
French (fr)
Other versions
WO1997031104A2 (en
Inventor
Jessica A Gorman
Darin B Ostrander
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Priority to AU22043/97A priority Critical patent/AU2204397A/en
Publication of WO1997031104A2 publication Critical patent/WO1997031104A2/en
Publication of WO1997031104A3 publication Critical patent/WO1997031104A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • C07K14/40—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts from Candida
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Toxicology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

An isolated nucleic acid molecule encoding C. albicans profilin. Preferably, the C. albicans profilin has the amino acid sequence of SEQ. ID. NO.: 2 and the nucleotide sequence of SEQ. ID. NO.: 1. The invention also concerns a nucleic acid molecule having a sequence complementary to the above sequences of 5' and 3' flanking regions thereof. The invention further concerns nucleic acid vectors comprising a DNA sequence coding for C. albicans profilin, host cells containing such vectors, and polypeptides comprising C. albicans profilin. Preferably, the polypeptide is full-length C. albicans profilin or recombinantly produced C. albicans profilin. The present invention also concerns methods for detecting nucleic acids coding for C. albicans profilin and for detecting anti-fungal agents that target C. albicans profilin.
PCT/US1997/003798 1996-02-22 1997-02-20 Candida albicans profilin gene WO1997031104A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU22043/97A AU2204397A (en) 1996-02-22 1997-02-20 Candida albicans profilin gene

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1207696P 1996-02-22 1996-02-22
US60/012,076 1996-02-22

Publications (2)

Publication Number Publication Date
WO1997031104A2 WO1997031104A2 (en) 1997-08-28
WO1997031104A3 true WO1997031104A3 (en) 1997-10-23

Family

ID=21753273

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1997/003798 WO1997031104A2 (en) 1996-02-22 1997-02-20 Candida albicans profilin gene

Country Status (2)

Country Link
AU (1) AU2204397A (en)
WO (1) WO1997031104A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6743897B1 (en) 2000-11-27 2004-06-01 Cytokinetics, Inc. Aspergillus fumigatus profilin
US6403372B1 (en) 2000-11-27 2002-06-11 Cytokinetics, Inc. Aspergillus fumigatus profilin

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL Emfun:caprofil;access-no:L37834 OSTRANDER D.B. 21-JUN-1996,last version *
DATABASE EMBL Swissprot:Prof-Canal;access-no:P53696 OSTRANDER D.B. 1-OCT-1996,last version *
OECHSNER, ULRICH ET AL: "The cDNA and deduced amino acid sequence of profilin from Saccharomyces cerevisiae", NUCLEIC ACIDS RES. (1987), 15(21), 9078 CODEN: NARHAD;ISSN: 0305-1048, XP002039725 *

Also Published As

Publication number Publication date
WO1997031104A2 (en) 1997-08-28
AU2204397A (en) 1997-09-10

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