IL132614A0 - Human toll-like receptor proteins related reagents and methods - Google Patents

Human toll-like receptor proteins related reagents and methods

Info

Publication number
IL132614A0
IL132614A0 IL13261498A IL13261498A IL132614A0 IL 132614 A0 IL132614 A0 IL 132614A0 IL 13261498 A IL13261498 A IL 13261498A IL 13261498 A IL13261498 A IL 13261498A IL 132614 A0 IL132614 A0 IL 132614A0
Authority
IL
Israel
Prior art keywords
methods
receptor proteins
proteins related
related reagents
human toll
Prior art date
Application number
IL13261498A
Other languages
English (en)
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27366459&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL132614(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp filed Critical Schering Corp
Publication of IL132614A0 publication Critical patent/IL132614A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL13261498A 1997-05-07 1998-05-07 Human toll-like receptor proteins related reagents and methods IL132614A0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US4429397P 1997-05-07 1997-05-07
US7221298P 1998-01-22 1998-01-22
US7694798P 1998-03-05 1998-03-05
PCT/US1998/008979 WO1998050547A2 (en) 1997-05-07 1998-05-07 Human toll-like receptor proteins, related reagents and methods

Publications (1)

Publication Number Publication Date
IL132614A0 true IL132614A0 (en) 2001-03-19

Family

ID=27366459

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13261498A IL132614A0 (en) 1997-05-07 1998-05-07 Human toll-like receptor proteins related reagents and methods

Country Status (19)

Country Link
EP (4) EP1988166A1 (enExample)
JP (4) JP2002514083A (enExample)
KR (1) KR100388860B1 (enExample)
CN (4) CN1225555C (enExample)
AT (3) ATE443139T1 (enExample)
AU (1) AU740333B2 (enExample)
CA (1) CA2289912C (enExample)
CY (1) CY1109645T1 (enExample)
DE (3) DE69836630T2 (enExample)
DK (2) DK0980429T3 (enExample)
ES (3) ES2279572T3 (enExample)
ID (1) ID28299A (enExample)
IL (1) IL132614A0 (enExample)
NO (1) NO995458D0 (enExample)
NZ (1) NZ338073A (enExample)
PL (1) PL336635A1 (enExample)
PT (1) PT1798288E (enExample)
SK (1) SK146599A3 (enExample)
WO (1) WO1998050547A2 (enExample)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8212004B2 (en) 1999-03-02 2012-07-03 Human Genome Sciences, Inc. Neutrokine-alpha fusion proteins
US6812327B1 (en) 1996-10-25 2004-11-02 Human Genome Sciences, Inc. Neutrokine-alpha polypeptides
US7696327B1 (en) 1997-10-17 2010-04-13 Genentech, Inc. Antibodies to human Toll homologues
US20030032090A1 (en) 1997-05-07 2003-02-13 Schering Corporation, A New Jersey Corporation Human receptor proteins; related reagents and methods
WO2001090151A2 (en) * 2000-05-25 2001-11-29 Schering Corporation Human receptor proteins; related reagents and methods
AU2003203679B2 (en) * 1997-10-17 2007-04-05 Genentech, Inc. Human toll homologues
AU1070399A (en) * 1997-10-17 1999-05-10 Genentech Inc. Human toll homologues
JP2000128900A (ja) * 1998-10-26 2000-05-09 Japan Science & Technology Corp 新規トル様（Ｔｏｌｌ−ｌｉｋｅ）レセプター及びその遺伝子
US6303321B1 (en) 1999-02-11 2001-10-16 North Shore-Long Island Jewish Research Institute Methods for diagnosing sepsis
US6740487B1 (en) * 1999-06-10 2004-05-25 University Of Iowa Research Foundation Variant TLR4 nucleic acid and uses thereof
ATE421584T1 (de) * 1999-11-02 2009-02-15 Novartis Vaccines & Diagnostic Cpg rezeptor (cpg-r) und darauf bezogene methoden
GB9927332D0 (en) * 1999-11-18 2000-01-12 Leiv Eiriksson Nyfotek As Novel antibody and uses thereof
GB0001704D0 (en) * 2000-01-25 2000-03-15 Glaxo Group Ltd Protein
US20030083244A1 (en) * 2000-04-26 2003-05-01 Vernet Corine A.M. Novel proteins and nucleic acids encoding same
US7879328B2 (en) 2000-06-16 2011-02-01 Human Genome Sciences, Inc. Antibodies that immunospecifically bind to B lymphocyte stimulator
AU2001268427B2 (en) 2000-06-16 2007-03-29 Glaxosmithkline Intellectual Property Limited Antibodies that immunospecifically bind to blys
JP2002034565A (ja) * 2000-07-19 2002-02-05 Japan Science & Technology Corp 細菌ｄｎａを特異的に認識する受容体タンパク質
EP2267017A3 (en) * 2000-08-18 2011-07-06 Human Genome Sciences, Inc. Binding polypeptides for B lymphocyte stimulator protein (BLyS)
AU2001288301A1 (en) 2000-08-18 2002-03-04 Human Genome Sciences, Inc. Binding polypeptides and methods based thereon
EP1366077B1 (en) 2000-09-15 2011-05-25 Coley Pharmaceutical GmbH PROCESS FOR HIGH THROUGHPUT SCREENING OF CpG-BASED IMMUNO-AGONIST/ANTAGONIST
US7304034B2 (en) 2001-05-15 2007-12-04 The Feinstein Institute For Medical Research Use of HMGB fragments as anti-inflammatory agents
US7220723B2 (en) 2001-05-15 2007-05-22 The Feinstein Institute For Medical Research Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents
WO2003031573A2 (en) * 2001-10-05 2003-04-17 Coley Pharmaceutical Gmbh Toll-like receptor 3 signaling agonists and antagonists
DK1719511T3 (da) * 2001-11-16 2009-04-14 Coley Pharm Group Inc N-[4-(4-amino-2-ethyl-1H-imidazo[4,5-c]quinolin-1-yl)butyl]methansulfonamid, en farmaceutisk sammensætning omfattende samme, og anvendelse deraf
GB0127618D0 (en) * 2001-11-17 2002-01-09 Univ Nottingham "Composition and method for treatment of wounds"
JP2004016021A (ja) 2002-06-12 2004-01-22 Japan Science & Technology Corp 抗体および阻害剤並びにそれを用いた形質転換方法および形質転換キット
AU2003287316A1 (en) * 2002-12-11 2004-06-30 3M Innovative Properties Company Assays relating to toll-like receptor activity
WO2004094671A2 (en) * 2003-04-22 2004-11-04 Coley Pharmaceutical Gmbh Methods and products for identification and assessment of tlr ligands
US7696169B2 (en) 2003-06-06 2010-04-13 The Feinstein Institute For Medical Research Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents
AU2004272607B2 (en) 2003-09-11 2008-11-06 Cornerstone Therapeutics Inc. Monoclonal antibodies against HMGB1
TW200514850A (en) * 2003-10-03 2005-05-01 Hitachi Chemical Co Ltd Method of evaluating risk for viral infection
US8871782B2 (en) 2003-10-03 2014-10-28 3M Innovative Properties Company Alkoxy substituted imidazoquinolines
TW200516153A (en) * 2003-10-03 2005-05-16 Hitachi Chemical Co Ltd Human toll-like receptor 3 gene polymorphism as marker for inherited factor of allergic disease and utilization of the same
JP2007514648A (ja) 2003-10-24 2007-06-07 エーザイ株式会社 Ｔｏｌｌ−ｌｉｋｅｒｅｃｅｐｔｏｒ２に関連する疾患及び状態を治療するための化合物及び方法
AR046781A1 (es) 2003-11-25 2005-12-21 3M Innovative Properties Co Derivados de imidazoquinolinas. composiciones farmaceuticas.
JP2008022701A (ja) * 2004-09-24 2008-02-07 Japan Science & Technology Agency 可溶型Ｔｏｌｌ様受容体４タンパク質
WO2006054129A1 (en) 2004-11-19 2006-05-26 Institut Gustave Roussy Improved treatment of cancer by double-stranded rna
AR051836A1 (es) 2004-11-30 2007-02-14 Centocor Inc Antagonistas de receptor 3 simil toll metodos y usos
AU2006210392A1 (en) 2005-02-04 2006-08-10 Coley Pharmaceutical Group, Inc. Aqueous gel formulations containing immune response modifiers
US7700728B2 (en) 2005-03-24 2010-04-20 Schering Corporation Use of chimeric receptors in a screening assay for identifying agonists and antagonists of cell receptors
US7498409B2 (en) 2005-03-24 2009-03-03 Schering Corporation Screening assay for TLR7, TLR8 and TLR9 agonists and antagonists
US9168286B2 (en) 2005-10-13 2015-10-27 Human Genome Sciences, Inc. Methods and compositions for use in treatment of patients with autoantibody positive disease
ES2435775T3 (es) 2005-10-27 2013-12-23 Janssen Biotech, Inc. Moduladores de receptor tipo Toll 3, procedimientos y usos
ES2555544T3 (es) 2006-03-07 2016-01-04 Vaxinnate Corporation Composiciones que incluyen hemaglutinina, métodos de preparación y métodos de uso de las mismas
WO2007123765A2 (en) 2006-03-31 2007-11-01 Human Genome Sciences Inc. Neutrokine-alpha and neutrokine-alpha splice variant
CN101134046B (zh) * 2006-09-01 2011-10-05 中国医学科学院药物研究所 Tlr4和tlr9激动剂复方在抑制肿瘤转移中的应用
EP2155889A4 (en) * 2007-05-25 2010-06-16 Centocor Ortho Biotech Inc TOLL RECEPTOR 3 MODULATORS AND USES THEREOF
AU2009239655B2 (en) 2008-04-25 2014-05-22 Innate Pharma Improved TLR3 agonist compositions
EP2116602A1 (en) 2008-05-07 2009-11-11 Institut Gustave Roussy Combination products for treating cancer
WO2010031749A1 (en) 2008-09-17 2010-03-25 Innate Pharma Compositions and methods for detecting tlr3
US9512196B2 (en) 2008-09-22 2016-12-06 Cedars-Sinai Medical Center Short-form human MD-2 as a negative regulator of toll-like receptor 4 signaling
WO2010033294A1 (en) 2008-09-22 2010-03-25 Cedars-Sinai Medical Center Short-form human md-2 as a negative regulator of toll-like receptor 4 signaling
DK2451844T3 (en) 2009-07-10 2015-07-27 Innate Pharma Tlr3-retention agents
WO2011021524A1 (ja) * 2009-08-19 2011-02-24 国立大学法人名古屋大学 乳酸菌の付着性を誘導するペプチド及びその用途
US9890202B2 (en) 2010-07-19 2018-02-13 Yeda Research And Development Co. Ltd. Peptides based on the transmembrane domain of a toll-like receptor (TLR) for treatment of TLR-mediated diseases
WO2013054329A1 (en) * 2011-10-10 2013-04-18 Yeda Research And Development Co. Ltd. Toll-like receptor 4 (tlr-4) agonist peptides for modulating tlr-4 mediated immune response
WO2012088272A1 (en) 2010-12-21 2012-06-28 Duke University Methods and compositions combining immunotherapy with monocyte activation
US20140065154A1 (en) 2011-01-12 2014-03-06 Innate Pharma Tlr3 binding agents
BR112013030894A2 (pt) 2011-06-01 2016-08-16 Janus Biotherapeutics Inc moduladores do sistema imune
AU2012262021B2 (en) 2011-06-01 2016-07-28 Janus Biotherapeutics, Inc. Novel immune system modulators
CA2850932A1 (en) 2011-10-04 2013-04-11 Janus Biotherapeutics, Inc. Novel imidazole quinoline-based immune system modulators
MX361773B (es) 2012-05-31 2018-12-17 Innate Pharma Agentes de ligación a tlr3.
US10017739B2 (en) 2012-09-06 2018-07-10 Duke University Methods of expanding and assessing B cells and using expanded B cells to treat disease
CN113502299B (zh) * 2021-07-20 2023-03-14 中国农业大学 一种抗金黄色葡萄球菌遗传修饰山羊生产方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2031216A1 (de) 1969-06-19 1971-01-14 Citizen Watch Co Ltd , Tokio Tag und Datum Stellvorrichtung fur Uhren mit Kalender
US3940475A (en) 1970-06-11 1976-02-24 Biological Developments, Inc. Radioimmune method of assaying quantitatively for a hapten
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
US3817837A (en) 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US3939350A (en) 1974-04-29 1976-02-17 Board Of Trustees Of The Leland Stanford Junior University Fluorescent immunoassay employing total reflection for activation
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4277437A (en) 1978-04-05 1981-07-07 Syva Company Kit for carrying out chemically induced fluorescence immunoassay
US4275149A (en) 1978-11-24 1981-06-23 Syva Company Macromolecular environment control in specific receptor assays
US4366241A (en) 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
US4659678A (en) 1982-09-29 1987-04-21 Serono Diagnostics Limited Immunoassay of antigens
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4859609A (en) 1986-04-30 1989-08-22 Genentech, Inc. Novel receptors for efficient determination of ligands and their antagonists or agonists
US5789192A (en) 1992-12-10 1998-08-04 Schering Corporation Mammalian receptors for interleukin-10 (IL-10)
WO1998002557A2 (en) * 1996-07-12 1998-01-22 Schering Corporation MAMMALIAN TNF-α CONVERTASES
ATE338117T1 (de) * 1997-08-01 2006-09-15 Serono Genetics Inst Sa 5' ests für proteine, die nicht gewebespezifisch sind
AU1070399A (en) * 1997-10-17 1999-05-10 Genentech Inc. Human toll homologues

Also Published As

Publication number Publication date
KR100388860B1 (ko) 2003-06-25
EP1925666B1 (en) 2010-02-17
CA2289912C (en) 2011-07-26
KR20010012323A (ko) 2001-02-15
CN1263555A (zh) 2000-08-16
EP1925666A1 (en) 2008-05-28
ES2279572T3 (es) 2007-08-16
JP2005120106A (ja) 2005-05-12
HK1112018A1 (en) 2008-08-22
AU7175498A (en) 1998-11-27
EP1988166A1 (en) 2008-11-05
EP1798288A2 (en) 2007-06-20
EP1798288B1 (en) 2009-09-16
ATE458053T1 (de) 2010-03-15
JP2009089713A (ja) 2009-04-30
EP0980429B1 (en) 2006-12-13
HK1102720A1 (en) 2007-12-07
NO995458L (no) 1999-11-08
JP2006052232A (ja) 2006-02-23
EP1798288A3 (en) 2007-09-12
NZ338073A (en) 2001-09-28
WO1998050547A2 (en) 1998-11-12
ID28299A (id) 2001-05-10
DE69836630D1 (de) 2007-01-25
PT1798288E (pt) 2009-12-23
ES2331622T3 (es) 2010-01-11
DE69836630T2 (de) 2007-10-11
ATE443139T1 (de) 2009-10-15
SK146599A3 (en) 2000-07-11
EP0980429A2 (en) 2000-02-23
ATE348157T1 (de) 2007-01-15
ES2340210T3 (es) 2010-05-31
PL336635A1 (en) 2000-07-03
HK1022175A1 (en) 2000-07-28
CN1800214A (zh) 2006-07-12
DK1798288T3 (da) 2010-01-04
CN1225555C (zh) 2005-11-02
NO995458D0 (no) 1999-11-08
CA2289912A1 (en) 1998-11-12
DK0980429T3 (da) 2007-04-10
CN101486759A (zh) 2009-07-22
WO1998050547A3 (en) 1999-03-11
CN1935840A (zh) 2007-03-28
CY1109645T1 (el) 2012-05-23
AU740333B2 (en) 2001-11-01
DE69841170D1 (de) 2009-10-29
JP2002514083A (ja) 2002-05-14
DE69841514D1 (de) 2010-04-01

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