IL130794A0 - Analogs of parathyroid hormone - Google Patents
Analogs of parathyroid hormoneInfo
- Publication number
- IL130794A0 IL130794A0 IL13079497A IL13079497A IL130794A0 IL 130794 A0 IL130794 A0 IL 130794A0 IL 13079497 A IL13079497 A IL 13079497A IL 13079497 A IL13079497 A IL 13079497A IL 130794 A0 IL130794 A0 IL 130794A0
- Authority
- IL
- Israel
- Prior art keywords
- analogs
- parathyroid hormone
- parathyroid
- hormone
- Prior art date
Links
- 102000003982 Parathyroid hormone Human genes 0.000 title 1
- 108090000445 Parathyroid hormone Proteins 0.000 title 1
- 239000000199 parathyroid hormone Substances 0.000 title 1
- 229960001319 parathyroid hormone Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Endocrinology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/779,768 US5969095A (en) | 1995-07-13 | 1997-01-07 | Analogs of parathyroid hormone |
| US08/813,534 US5955574A (en) | 1995-07-13 | 1997-03-07 | Analogs of parathyroid hormone |
| PCT/US1997/022498 WO1998030590A2 (en) | 1997-01-07 | 1997-12-08 | Analogs of parathyroid hormone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL130794A0 true IL130794A0 (en) | 2001-01-28 |
Family
ID=27119618
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13079497A IL130794A0 (en) | 1997-01-07 | 1997-12-08 | Analogs of parathyroid hormone |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US5955574A (da) |
| EP (3) | EP0948541B1 (da) |
| JP (1) | JP3963482B2 (da) |
| KR (2) | KR100497709B1 (da) |
| CN (1) | CN1137898C (da) |
| AR (3) | AR011517A1 (da) |
| AT (2) | ATE321784T1 (da) |
| AU (1) | AU741584B2 (da) |
| BR (1) | BR9714200A (da) |
| CA (1) | CA2276614C (da) |
| CZ (2) | CZ298937B6 (da) |
| DE (2) | DE69735603T2 (da) |
| DK (2) | DK1645566T3 (da) |
| ES (2) | ES2258286T3 (da) |
| HK (1) | HK1026215A1 (da) |
| HU (1) | HUP9904596A3 (da) |
| IL (1) | IL130794A0 (da) |
| NO (1) | NO993341L (da) |
| NZ (1) | NZ336610A (da) |
| PL (1) | PL191898B1 (da) |
| PT (2) | PT948541E (da) |
| RU (1) | RU2198182C2 (da) |
| SI (2) | SI0948541T1 (da) |
| WO (1) | WO1998030590A2 (da) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6544949B1 (en) * | 1995-07-13 | 2003-04-08 | Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. | Analogs of parathyroid hormone |
| US7410948B2 (en) * | 1995-07-13 | 2008-08-12 | Societe De Conseils De Recherches Et D'applications Scientifiques, Sas | Analogs of parathyroid hormone |
| ES2244090T3 (es) * | 1997-09-09 | 2005-12-01 | F. Hoffmann-La Roche Ag | Curacion de fracturas utilizando analogos de pthrp. |
| EP1075491B1 (en) * | 1998-05-05 | 2008-04-16 | Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. | Pth2 receptor selective compounds |
| HUP0104934A3 (en) * | 1998-07-20 | 2002-05-28 | Sod Conseils Rech Applic | Peptide analogues of pacap, pharmaceutical compositions comprising thereof and their use |
| US6660843B1 (en) † | 1998-10-23 | 2003-12-09 | Amgen Inc. | Modified peptides as therapeutic agents |
| EP1257576B1 (en) | 2000-02-18 | 2004-09-15 | Dabur Research Foundation | Vasoactive intestinal peptide analogs |
| US6756480B2 (en) | 2000-04-27 | 2004-06-29 | Amgen Inc. | Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein |
| US20050124537A1 (en) * | 2000-04-27 | 2005-06-09 | Amgen Inc. | Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein |
| CN1512892A (zh) * | 2001-06-01 | 2004-07-14 | ��˹��ŵ�� | 口服施用甲状旁腺激素和降钙素 |
| EP1439854B1 (en) * | 2001-07-23 | 2016-12-14 | The General Hospital Corporation | Conformationally constrained parathyroid hormone (pth) analogs |
| EP1651246A4 (en) * | 2003-08-06 | 2009-06-24 | Innophos Inc | PROCESS FOR PROMOTING BONE GROWTH |
| AU2006315132A1 (en) | 2005-11-10 | 2007-05-24 | Board Of Control Of Michigan Technological University | Black bear parathyroid hormone and methods of using black bear parathyroid hormone |
| USRE49444E1 (en) | 2006-10-03 | 2023-03-07 | Radius Health, Inc. | Method of treating osteoporosis comprising administration of PTHrP analog |
| WO2008063279A2 (en) * | 2006-10-03 | 2008-05-29 | Radius Health, Inc. | A stable composition comprising a bone anabolic protein, namely a pthrp analogue, and uses thereof |
| US7803770B2 (en) * | 2006-10-03 | 2010-09-28 | Radius Health, Inc. | Method of treating osteoporosis comprising administration of PTHrP analog |
| EP2084183B1 (en) * | 2006-10-13 | 2010-05-26 | Eli Lilly & Company | Pegylated pth as pth receptor modulators and uses thereof |
| CA3017668C (en) | 2007-08-01 | 2021-11-09 | The General Hospital Corporation | Screening methods using g-protein coupled receptors and related compositions |
| CN102448482A (zh) | 2009-03-27 | 2012-05-09 | 范安德尔研究所 | 甲状旁腺素肽和甲状旁腺素相关蛋白肽及使用方法 |
| EP2509996A1 (en) | 2009-12-07 | 2012-10-17 | Michigan Technological University | Black bear parathyroid hormone and methods of using black bear parathyroid hormone |
| EP3106159A1 (en) | 2010-05-12 | 2016-12-21 | Radius Health, Inc. | Therapeutic regimens |
| MX358161B (es) | 2010-05-13 | 2018-08-06 | The General Hospital Corp Star | Analogos de hormona paratiroidea y usos para los mismos. |
| ES2550319T3 (es) | 2010-09-28 | 2015-11-06 | Radius Health, Inc | Moduladores selectivos del receptor de andrógenos |
| BR112017023228A2 (pt) | 2015-04-29 | 2018-11-06 | Radius Pharmaceuticals Inc | métodos para tratamento de câncer |
| WO2017007777A2 (en) * | 2015-07-06 | 2017-01-12 | Zhengxin Dong | NOVEL FORMULATIONS OF PTHrP ANALOGUE |
| AU2017281038B2 (en) | 2016-06-22 | 2021-09-09 | Ellipses Pharma Ltd | AR+ breast cancer treatment methods |
| AU2018205285C9 (en) | 2017-01-05 | 2024-05-23 | Radius Pharmaceuticals, Inc. | Polymorphic forms of RAD1901-2HCl |
| US10996208B2 (en) | 2017-04-28 | 2021-05-04 | Radius Health, Inc. | Abaloparatide formulations and methods of testing, storing, modifying, and using same |
| CN112423844A (zh) | 2018-07-04 | 2021-02-26 | 雷迪厄斯制药公司 | Rad1901-2hcl的多晶型形式 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| IE52535B1 (en) | 1981-02-16 | 1987-12-09 | Ici Plc | Continuous release pharmaceutical compositions |
| FR2550204B1 (fr) * | 1983-08-05 | 1987-11-13 | Toyo Jozo Kk | Derives peptidiques de (nle8,nle1b, tyr34)-h-pth |
| EP0293158A3 (en) * | 1987-05-26 | 1990-05-09 | Merck & Co. Inc. | Parathyroid hormone antagonists |
| JPH03504201A (ja) * | 1989-02-23 | 1991-09-19 | ゲゼルシャフト・フュア・ビオテクノロギッシェ・フォルシュンク・ミット・ベシュレンクテル・ハフツング （ゲー・ベー・エフ） | Ｐｔｈ変種をコードするｄｎａ配列、ｐｔｈ変種、発現ベクター、細菌宿主、利用と治療用組成物 |
| CA2040264A1 (en) * | 1990-04-12 | 1991-10-13 | Tatsuhiko Kanmera | Parathyroid hormone antagonists |
| JPH0532696A (ja) * | 1990-09-28 | 1993-02-09 | Takeda Chem Ind Ltd | 副甲状腺ホルモン誘導体 |
| AU2807892A (en) * | 1991-10-10 | 1993-05-03 | Peter K.T. Pang | Parathyroid hormone analogues and use in osteoporosis treatment |
| US5434246A (en) * | 1992-03-19 | 1995-07-18 | Takeda Chemical Industries, Ltd. | Parathyroid hormone derivatives |
| CA2098639A1 (en) * | 1992-06-19 | 1993-12-20 | K. Anne Kronis | Bone stimulating, non-vasoactive parathyroid hormone variants |
| US5589452A (en) * | 1992-07-14 | 1996-12-31 | Syntex (U.S.A.) Inc. | Analogs of parathyroid hormone and parathyroid hormone related peptide: synthesis and use for the treatment of osteoporosis |
| US5821225A (en) * | 1992-07-14 | 1998-10-13 | Syntex (U.S.A.) Inc. | Method for the treatment of corticosteroid induced osteopenia comprising administration of modified PTH or PTHrp |
| AU672790B2 (en) * | 1992-07-15 | 1996-10-17 | Novartis Ag | Variants of parathyroid hormone and its fragments |
| ES2196023T3 (es) | 1993-01-06 | 2003-12-16 | Kinerton Ltd | Conjugados moleculares ionicos de poliesteres biodegradables y polipeptidos bioactivos. |
| CN1070500C (zh) * | 1993-07-13 | 2001-09-05 | 森德克斯(美国)股份有限公司 | 甲状旁腺激素类似物和甲状旁腺激素相关肽：合成和治疗骨质疏松症的用途 |
| WO1996019246A1 (en) * | 1994-12-19 | 1996-06-27 | Beth Israel Hospital Association | Continuous low-dose administration of parathyroid hormone or its agonist |
| CA2178894A1 (en) * | 1995-06-15 | 1996-12-16 | Tsunehiko Fukuda | Parathyroid hormone derivatives and their use |
| US5723577A (en) * | 1995-07-13 | 1998-03-03 | Biomeasure Inc. | Analogs of parathyroid hormone |
-
1997
- 1997-03-07 US US08/813,534 patent/US5955574A/en not_active Expired - Lifetime
- 1997-12-08 CA CA002276614A patent/CA2276614C/en not_active Expired - Fee Related
- 1997-12-08 RU RU99117145/04A patent/RU2198182C2/ru not_active IP Right Cessation
- 1997-12-08 KR KR10-1999-7006165A patent/KR100497709B1/ko not_active IP Right Cessation
- 1997-12-08 DK DK05026436.5T patent/DK1645566T3/da active
- 1997-12-08 BR BR9714200-0A patent/BR9714200A/pt not_active IP Right Cessation
- 1997-12-08 AT AT97951595T patent/ATE321784T1/de active
- 1997-12-08 SI SI9730730T patent/SI0948541T1/sl unknown
- 1997-12-08 EP EP97951595A patent/EP0948541B1/en not_active Expired - Lifetime
- 1997-12-08 NZ NZ336610A patent/NZ336610A/en not_active IP Right Cessation
- 1997-12-08 ES ES97951595T patent/ES2258286T3/es not_active Expired - Lifetime
- 1997-12-08 CZ CZ0239899A patent/CZ298937B6/cs not_active IP Right Cessation
- 1997-12-08 AT AT05026436T patent/ATE471342T1/de active
- 1997-12-08 AU AU55199/98A patent/AU741584B2/en not_active Ceased
- 1997-12-08 ES ES05026436T patent/ES2347154T3/es not_active Expired - Lifetime
- 1997-12-08 WO PCT/US1997/022498 patent/WO1998030590A2/en active IP Right Grant
- 1997-12-08 CZ CZ20050594A patent/CZ301497B6/cs not_active IP Right Cessation
- 1997-12-08 DE DE69735603T patent/DE69735603T2/de not_active Expired - Lifetime
- 1997-12-08 PT PT97951595T patent/PT948541E/pt unknown
- 1997-12-08 HU HU9904596A patent/HUP9904596A3/hu unknown
- 1997-12-08 IL IL13079497A patent/IL130794A0/xx not_active IP Right Cessation
- 1997-12-08 DE DE69739912T patent/DE69739912D1/de not_active Expired - Lifetime
- 1997-12-08 PL PL334438A patent/PL191898B1/pl not_active IP Right Cessation
- 1997-12-08 EP EP10156965A patent/EP2206725A1/en not_active Withdrawn
- 1997-12-08 SI SI9730795T patent/SI1645566T1/sl unknown
- 1997-12-08 DK DK97951595T patent/DK0948541T3/da active
- 1997-12-08 EP EP05026436A patent/EP1645566B1/en not_active Expired - Lifetime
- 1997-12-08 JP JP53086598A patent/JP3963482B2/ja not_active Expired - Fee Related
- 1997-12-08 KR KR1020057003295A patent/KR100699422B1/ko not_active IP Right Cessation
- 1997-12-08 CN CNB971819157A patent/CN1137898C/zh not_active Expired - Fee Related
- 1997-12-08 PT PT05026436T patent/PT1645566E/pt unknown
-
1998
- 1998-01-06 AR ARP980100058A patent/AR011517A1/es active IP Right Grant
-
1999
- 1999-07-06 NO NO993341A patent/NO993341L/no not_active Application Discontinuation
-
2000
- 2000-09-01 HK HK00105467A patent/HK1026215A1/xx not_active IP Right Cessation
-
2003
- 2003-02-17 AR ARP030100515A patent/AR038552A2/es active IP Right Grant
-
2006
- 2006-01-18 AR ARP060100191A patent/AR051906A2/es unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |