IL127564A0 - Solid oral dosage forms of valsartan - Google Patents

Solid oral dosage forms of valsartan

Info

Publication number
IL127564A0
IL127564A0 IL12756497A IL12756497A IL127564A0 IL 127564 A0 IL127564 A0 IL 127564A0 IL 12756497 A IL12756497 A IL 12756497A IL 12756497 A IL12756497 A IL 12756497A IL 127564 A0 IL127564 A0 IL 127564A0
Authority
IL
Israel
Prior art keywords
valsartan
dosage forms
oral dosage
solid oral
solid
Prior art date
Application number
IL12756497A
Other languages
English (en)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10795969&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL127564(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of IL127564A0 publication Critical patent/IL127564A0/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL12756497A 1996-06-27 1997-06-18 Solid oral dosage forms of valsartan IL127564A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9613470.5A GB9613470D0 (en) 1996-06-27 1996-06-27 Small solid oral dosage form
PCT/EP1997/003172 WO1997049394A2 (en) 1996-06-27 1997-06-18 Sold oral dosage forms of valsartan

Publications (1)

Publication Number Publication Date
IL127564A0 true IL127564A0 (en) 1999-10-28

Family

ID=10795969

Family Applications (2)

Application Number Title Priority Date Filing Date
IL12756497A IL127564A0 (en) 1996-06-27 1997-06-18 Solid oral dosage forms of valsartan
IL195339A IL195339A0 (en) 1996-06-27 2008-11-17 Solid oral dosage forms of valsartan

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL195339A IL195339A0 (en) 1996-06-27 2008-11-17 Solid oral dosage forms of valsartan

Country Status (32)

Country Link
US (3) US6294197B1 (cs)
EP (7) EP0914119B1 (cs)
JP (5) JP2000506540A (cs)
KR (6) KR100618038B1 (cs)
CN (3) CN1475207B (cs)
AR (2) AR008618A1 (cs)
AT (3) ATE276750T1 (cs)
BR (1) BR9709956A (cs)
CA (2) CA2673462C (cs)
CO (1) CO4870755A1 (cs)
CY (1) CY2553B1 (cs)
CZ (1) CZ296850B6 (cs)
DE (3) DE69730834T2 (cs)
DK (3) DK1767206T3 (cs)
ES (3) ES2290400T3 (cs)
GB (1) GB9613470D0 (cs)
HU (1) HU229134B1 (cs)
ID (1) ID17553A (cs)
IL (2) IL127564A0 (cs)
MY (3) MY156312A (cs)
NO (2) NO317181B1 (cs)
NZ (2) NZ333385A (cs)
PE (1) PE87498A1 (cs)
PL (2) PL188233B1 (cs)
PT (3) PT1410797E (cs)
RU (5) RU2203054C2 (cs)
SI (2) SI0914119T1 (cs)
SK (1) SK285902B6 (cs)
TR (1) TR199802698T2 (cs)
TW (1) TW473394B (cs)
WO (1) WO1997049394A2 (cs)
ZA (1) ZA975673B (cs)

Families Citing this family (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9613470D0 (en) * 1996-06-27 1996-08-28 Ciba Geigy Ag Small solid oral dosage form
US20030045561A1 (en) * 2001-02-06 2003-03-06 Smithkline Beecham Corporation Method of treating isolated systolic hypertension
IL137979A0 (en) * 1998-03-04 2001-10-31 Takeda Chemical Industries Ltd Production, release preparation for aii antagonist-sustained and use thereof
EP1121103B1 (en) 1998-05-18 2006-12-20 Takeda Pharmaceutical Company Limited Orally disintegrable tablets comprising a benzimidazole
CZ304359B6 (cs) * 1998-07-10 2014-03-26 Novartis Ag Farmaceutická kombinační kompozice
HUP0104780A3 (en) 1998-12-23 2002-11-28 Novartis Ag Use of at-1 receptor antagonist or at-2 receptor modulator for treating diseases associated with an increase of at-1 or at-2 receptors
CN101011390A (zh) 1999-01-26 2007-08-08 诺瓦提斯公司 血管紧张素ⅱ受体拮抗剂在治疗急性心肌梗塞中的应用
ES2265910T3 (es) * 1999-01-26 2007-03-01 Novartis Ag Uso de antagonistas de receptores de angiotensina ii para el tratamiento de infarto agudo de miocardio.
JP2003507418A (ja) * 1999-08-24 2003-02-25 メディキュア インターナショナル インコーポレイテッド 心血管疾患とその関連疾患の治療
DE10014416B4 (de) * 2000-03-24 2009-02-19 3M Espe Ag Verwendung feinkörniger Pulver bzw. Pulvergemische zur Herstellung eines Mittels für supragingivales Pulverstrahlen
CA2311734C (en) * 2000-04-12 2011-03-08 Bristol-Myers Squibb Company Flash-melt oral dosage formulation
US20020132839A1 (en) * 2000-06-22 2002-09-19 Ganter Sabina Maria Tablet formulations comprising valsartan
AU2005200815B2 (en) * 2000-06-22 2008-01-17 Novartis Ag Solid valsartan pharmaceutical compositions
JP2003535895A (ja) * 2000-06-22 2003-12-02 ノバルティス アクチエンゲゼルシャフト 固体バルサルタン医薬組成物
PT1313714E (pt) 2000-07-19 2008-11-03 Novartis Ag Sais de valsartan
PE20020617A1 (es) * 2000-08-22 2002-08-05 Novartis Ag Composicion que comprende un antagonista del receptor at1 y un potenciador de la secrecion de insulina o un sensibilizante a la insulina
US20060089389A1 (en) 2000-08-22 2006-04-27 Malcolm Allison Combination
US8168616B1 (en) 2000-11-17 2012-05-01 Novartis Ag Combination comprising a renin inhibitor and an angiotensin receptor inhibitor for hypertension
EP1413315A4 (en) * 2001-08-03 2006-08-16 Takeda Pharmaceutical DRUGS WITH CONTINUOUS RELEASE
GB0209265D0 (en) 2002-04-23 2002-06-05 Novartis Ag Organic compounds
EG24716A (en) 2002-05-17 2010-06-07 Novartis Ag Combination of organic compounds
DE10230272A1 (de) * 2002-07-05 2004-01-22 Solvay Pharmaceuticals Gmbh AT1-Rezeptorantagonisten zur Prävention von Folgeschlaganfällen
EP1382334A1 (en) * 2002-07-11 2004-01-21 Université de Picardie Jules Verne Use of angiotensin II AT1-receptor blockers (ARB), alone or combined with thiazide or angiotensin II for the treatment of stroke
ES2238022T3 (es) * 2003-03-17 2008-11-01 Teva Pharmaceutical Industries Ltd. Poliformos de valsartan.
US7199144B2 (en) * 2003-04-21 2007-04-03 Teva Pharmaceuticals Industries, Ltd. Process for the preparation of valsartan and intermediates thereof
EP1950204A1 (en) 2003-03-17 2008-07-30 Teva Pharmaceutical Industries Ltd. Amorphous form of valsartan
EP1618097A1 (en) * 2003-04-21 2006-01-25 Teva Pharmaceutical Industries Ltd Process for the preparation of valsartan
WO2004094391A2 (en) * 2003-04-21 2004-11-04 Teva Pharmaceutical Industries Ltd. Process for the preparation of valsartan and intermediates thereof
JP4505859B2 (ja) * 2003-08-08 2010-07-21 味の素株式会社 ナテグリニド含有製剤
GB0325605D0 (en) * 2003-11-03 2003-12-10 Novartis Ag Combination of organic compounds
EA008063B1 (ru) * 2003-11-03 2007-02-27 Зентива А.С. Рецептура, содержащая валсартан (valsartan)
JP2005187793A (ja) * 2003-12-24 2005-07-14 Rohm & Haas Electronic Materials Llc 改良された接着剤
WO2005082329A2 (en) * 2004-02-19 2005-09-09 Ranbaxy Laboratories Limited Process for the preparation of solid dosage forms of valsartan and hydrochlorthiazide
WO2005089720A1 (en) * 2004-03-10 2005-09-29 Ranbaxy Laboratories Limited Valsartan tablets and the process for the preparation thereof
CN1976926A (zh) 2004-09-02 2007-06-06 特瓦制药工业有限公司 奥美沙坦酯的制备
EP3459532A1 (en) * 2004-10-08 2019-03-27 Fwp Ip Aps Controlled release pharmaceutical compositions comprising a fumaric acid ester
JP4705108B2 (ja) * 2004-10-15 2011-06-22 ズートツッカー アクチェンゲゼルシャフト マンハイム/オクセンフルト 改良されたパンコーティング法
ME01453B (me) * 2004-12-24 2014-04-20 Krka Tovarna Zdravil D D Novo Mesto Čvrste farmaceutske kompozicije koje sadrže valsartan
EP1674080A1 (en) * 2004-12-24 2006-06-28 KRKA, D.D., Novo Mesto Solid pharmaceutical composition comprising valsartan
FR2882260A1 (fr) * 2005-02-21 2006-08-25 Flamel Technologies Sa Forme pharmaceutique orale multimicroparticulaire a liberation modifiee d'antagonistes des recepteurs de l'angiotensine ii
JP2008545742A (ja) * 2005-05-31 2008-12-18 マイラン ラボラトリーズ インク. ネビボロールを含む組成物
WO2007005967A2 (en) * 2005-07-05 2007-01-11 Teva Pharmaceutical Industries Ltd. Process for preparing valsartan
GB0513888D0 (en) * 2005-07-06 2005-08-10 Btg Int Ltd Core 2 GLCNAC-T Inhibitors II
WO2007052307A2 (en) * 2005-10-31 2007-05-10 Lupin Limited Stable solid oral dosage forms of valsartan
RU2309732C1 (ru) * 2006-03-13 2007-11-10 Олег Ильич Эпштейн Спрессованная твердая оральная форма лекарственного препарата и способ получения твердой оральной формы лекарственного препарата
EP2007385A4 (en) * 2006-03-23 2010-08-18 Sinai School Medicine CARDIOVASCULAR COMPOSITION AND ITS USE FOR THE TREATMENT OF MORBUS ALZHEIMER
WO2007149010A1 (fr) 2006-06-06 2007-12-27 Oleg Iliich Epshtein Préparation médicamenteuse destinée au traitement peroral de l'excès pondéral, du diabète sucré et de maladies accompagnées d'une perturbation de la tolérance du glucose
GB0612540D0 (en) 2006-06-23 2006-08-02 Novartis Ag Galenical formulations of organic compounds
US20090304797A1 (en) * 2006-06-23 2009-12-10 Tarur Venkatasubramanian Radha Process for the Preparation of Micronized Valsartan
EP1897537A1 (en) * 2006-09-04 2008-03-12 Novartis AG Composition comprising an angiotensin II receptor antagonist
PE20081364A1 (es) * 2006-09-04 2008-12-04 Novartis Ag Composicion farmaceutica que comprende valsartan
JP2010508266A (ja) * 2006-10-30 2010-03-18 ハナル ファーマシューティカル カンパニー リミテッド チアジド系化合物およびアンジオテンシン−ii−受容体遮断剤を含む放出性が制御された薬学的組成物
WO2008064338A2 (en) * 2006-11-22 2008-05-29 Rubicon Research Pvt. Ltd. Valsartan formulation for pulsatile delivery
CA2681708A1 (en) * 2007-03-29 2008-10-09 Alembic Limited Valsartan tablet formulations
TR200703568A1 (tr) 2007-05-24 2008-07-21 Sanovel �La� Sanay� Ve T�Caret Anon�M ��Rket� Valsartan formülasyonları
ES2686081T3 (es) * 2007-07-31 2018-10-16 Cargill, Incorporated Dextrosa comprimible directamente
GB0715628D0 (en) * 2007-08-10 2007-09-19 Generics Uk Ltd Solid valsartan composition
CN101396366B (zh) * 2007-09-25 2010-10-13 浙江华海药业股份有限公司 含缬沙坦的固体口服制剂及其制备方法
TW200924737A (en) * 2007-09-28 2009-06-16 Novartis Ag Galenical formulations of organic compounds
AU2008311053B2 (en) 2007-10-09 2012-08-30 Novartis Ag Pharmaceutical formulation of valsartan
MY153730A (en) * 2007-11-06 2015-03-13 Novartis Ag Dual-acting pharmaceutical compositions based on superstructures of angiotensin receptor antagonist/blocker (arb) and neutral endopeptidase (nep) inhibitor
EP2067470A1 (en) * 2007-12-03 2009-06-10 Laboratorios Lesvi, S.L. Pharmaceutical compositions containing valsartan and process for its preparation
EP2240163A1 (en) * 2007-12-31 2010-10-20 Lupin Limited Pharmaceutical compositions of amlodipine and valsartan
CN101951902A (zh) * 2008-02-28 2011-01-19 诺瓦提斯公司 缬沙坦固体口服剂型以及制备该制剂的方法
US20090226516A1 (en) * 2008-03-04 2009-09-10 Pharma Pass Ii Llc Sartan compositions
US20090226515A1 (en) * 2008-03-04 2009-09-10 Pharma Pass Ii Llc Statin compositions
EP2281557A4 (en) * 2008-04-29 2011-08-31 Hanall Biopharma Co Ltd PHARMACEUTICAL FORMULATION CONTAINING AN ANGIOTENSIN II RECEPTOR BLOCKING AGENT
AU2009257174A1 (en) * 2008-06-09 2009-12-17 Dimerix Bioscience Pty Ltd Novel receptor hetero-dimers/-oligomers
KR101033975B1 (ko) * 2008-10-10 2011-05-11 이희엽 직접압축법을 이용한 발사르탄 함유 고형 경구 제형의 제조방법 및 이에 따라 제조된 고형 경구 제형
DE102008051783A1 (de) * 2008-10-17 2010-04-22 Tiefenbacher Pharmachemikalien Alfred E. Tiefenbacher Gmbh & Co. Kg Valsartan enthaltende Tablette
WO2010075347A2 (en) 2008-12-23 2010-07-01 Takeda Pharmaceutical Company Limited Methods of treating hypertension with at least one angiotensin ii receptor blocker and chlorthalidone
EP2405899A2 (en) 2009-03-11 2012-01-18 Sanovel Ilaç Sanayi Ve Ticaret Anonim Sirketi Valsartan formulations
RU2398570C1 (ru) * 2009-04-17 2010-09-10 Илья Николаевич Медведев Способ снижения содержания микровезикул в крови при стабильной стенокардии напряжения i-ii функционального класса с артериальной гипертонией
WO2011027021A1 (en) * 2009-09-01 2011-03-10 Orion Corporation A method for the treatment of hypertension
KR101084783B1 (ko) * 2009-09-01 2011-11-22 삼성에스디아이 주식회사 이차 전지 및 그의 제조 방법
ES2364011B1 (es) 2009-11-20 2013-01-24 Gp Pharm, S.A. Cápsulas de principios activos farmacéuticos y ésteres de ácidos grasos poliinsaturados para el tratamiento de enfermedades cardiovasculares.
CN101897675B (zh) * 2010-02-10 2012-11-21 温士顿医药股份有限公司 含有凡尔沙坦或其药学上可接受的盐的固体剂型口服医药组成物
EP2536396B1 (en) 2010-02-16 2016-08-10 KRKA, D.D., Novo Mesto Process for the preparation of oral solid dosage forms comprising valsartan
AR083417A1 (es) 2010-10-14 2013-02-21 Novartis Ag Composiciones farmaceuticas que contienen un dgat1 inhibidor
JP5882796B2 (ja) 2011-03-31 2016-03-09 キヤノン株式会社 振動体の駆動方法、振動装置、該振動装置を有する駆動装置、及び光学機器
GB201116993D0 (en) * 2011-10-03 2011-11-16 Ems Sa Pharmaceutical compositions of antihypertensives
BR112014015620A8 (pt) 2011-12-26 2017-07-04 Novartis Ag comprimidos e agentes revestidos a seco
WO2013098578A1 (en) 2011-12-31 2013-07-04 Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi Immediate release pharmaceutical composition of valsartan hydrochlorothiazide
WO2013098576A1 (en) 2011-12-31 2013-07-04 Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi Immediate release pharmaceutical composition of valsartan
JP6018420B2 (ja) * 2012-06-05 2016-11-02 ニプロ株式会社 アンジオテンシンii受容体拮抗薬およびサイアザイド系利尿薬を含む医薬組成物
WO2014038895A1 (ko) * 2012-09-06 2014-03-13 한국콜마주식회사 발사르탄 함유 고형 경구제형 및 그 제조방법
JP2014062064A (ja) * 2012-09-21 2014-04-10 Ohara Yakuhin Kogyo Kk バルサルタン含有錠剤の製造方法
JP6238831B2 (ja) * 2014-04-25 2017-11-29 沢井製薬株式会社 バルサルタン含有錠剤及びその製造方法
JP6141472B2 (ja) * 2016-03-02 2017-06-07 大原薬品工業株式会社 バルサルタン含有錠剤の製造方法
WO2018002673A1 (en) 2016-07-01 2018-01-04 N4 Pharma Uk Limited Novel formulations of angiotensin ii receptor antagonists
EP3807898A1 (en) 2018-06-14 2021-04-21 AstraZeneca UK Limited Methods for treatment of hypertension with an angiotensin ii receptor blocker pharmaceutical composition
EP4295839A1 (en) 2022-06-20 2023-12-27 KRKA, d.d., Novo mesto Combination of valsartan and indapamide

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3200039A (en) 1962-05-28 1965-08-10 Pfizer & Co C Non-granulated tablets with 20% sorbitol in a particle size of from about 100mu to about 2000mu
GB1422176A (en) 1973-05-05 1976-01-21 Beecham Group Ltd Pharmaceutical tablets
AU528098B2 (en) 1978-11-16 1983-04-14 Beecham Group Plc Analgesic tablet
US4353887A (en) 1979-08-16 1982-10-12 Ciba-Geigy Corporation Divisible tablet having controlled and delayed release of the active substance
US4238485A (en) * 1979-10-29 1980-12-09 Merck & Co., Inc. Novel pharmaceutical compositions
EP0070127A3 (en) 1981-07-10 1983-08-17 Beecham Group Plc Tablets
US4543359A (en) * 1982-10-01 1985-09-24 Eaton Laboratories, Inc. Treating cardiac arrhythmias with dantrolene sodium
HU187215B (en) * 1983-01-26 1985-11-28 Egyt Gyogyszervegyeszeti Gyar Method for producing pharmaceutical product of high actor content and prolonged effect
US4609675A (en) * 1984-08-17 1986-09-02 The Upjohn Company Stable, high dose, high bulk density ibuprofen granulations for tablet and capsule manufacturing
US4743612A (en) * 1986-10-17 1988-05-10 Berlex Laboratories, Inc. Prodrug derivatives of the cardiotonic agent 4-ethyl-1,3-dihydro-5-(4-(2-methyl-1H-imidazol-1-yl)benzoyl)-2H-imidazol-2-one, composition containing them, and method of using them to treat cardiac failure
DE3705055A1 (de) * 1987-02-18 1988-09-01 Boehringer Ingelheim Kg Verwendung von 2-(3-fluor-4-methylphenylimino)-imidazolidin zur behandlung der koronaren herzkrankheit
JP2518854B2 (ja) * 1987-06-19 1996-07-31 旭化成工業株式会社 固形製剤の製法
DE3739779A1 (de) * 1987-11-24 1989-06-08 Beiersdorf Ag Pharmazeutische praeparate
SE506179C2 (sv) * 1989-01-23 1997-11-17 Ciba Geigy Ag Farmaceutisk lågkomposition av benazepril och ett tiaziddiuretikum
GB8909793D0 (en) 1989-04-28 1989-06-14 Beecham Group Plc Pharmaceutical formulation
DE59107440D1 (de) * 1990-02-19 1996-04-04 Ciba Geigy Ag Acylverbindungen
CA2092565A1 (en) * 1990-09-28 1992-03-29 Robert T. Sims Ibuprofen-diuretic combinations
DE69331839T2 (de) * 1992-01-29 2002-12-12 Takeda Chemical Industries, Ltd. Schnellösliche Tablette und ihre Herstellung
IL104755A0 (en) 1992-02-17 1993-06-10 Ciba Geigy Ag Treatment of glaucoma
US5395627A (en) * 1992-09-04 1995-03-07 Akzo N.V. Pharmaceutical granulate
IT1255522B (it) * 1992-09-24 1995-11-09 Ubaldo Conte Compressa per impiego terapeutico atta a cedere una o piu' sostanze attive con differenti velocita'
WO1994009778A1 (en) 1992-10-26 1994-05-11 Merck & Co., Inc. Combinations of angiotensin-ii receptor antagonists and diuretics
AU5745394A (en) 1992-12-30 1994-08-15 Fmc Corporation Readily available konjac glucomannan sustained release excipient
JP3057471B2 (ja) * 1993-06-07 2000-06-26 武田薬品工業株式会社 アンジオテンシンii介在性諸疾患の予防または治療剤
US5464854A (en) 1993-11-11 1995-11-07 Depadova; Anathony S. Method of modifying ovarian hormone-regulated AT1 receptor activity as treatment of incapacitating symptom(s) of P.M.S.
AT401871B (de) * 1994-01-28 1996-12-27 Gebro Broschek Gmbh Verfahren zur herstellung von s(+)-ibuprofen- partikeln mit verbesserten fliesseigenschaften und deren verwendung zur arzneimittelherstellung
JP3534130B2 (ja) * 1994-03-01 2004-06-07 旭化成ケミカルズ株式会社 医薬品組成物
GB9404010D0 (en) * 1994-03-02 1994-04-20 Opt Tel Services Limited Telephone dialling monitoring and route selecting apparatus
PL316259A1 (en) * 1994-03-17 1997-01-06 Ciba Geigy Ag Treatment of diabetic nephropathy with valsartan
GB9408117D0 (en) 1994-04-23 1994-06-15 Smithkline Beecham Corp Pharmaceutical formulations
DE19502065C2 (de) * 1995-01-14 1996-05-02 Prophyta Biolog Pflanzenschutz Pilzisolat mit fungizider Wirkung
US5994348A (en) * 1995-06-07 1999-11-30 Sanofi Pharmaceutical compositions containing irbesartan
FR2735365B1 (fr) * 1995-06-14 1997-09-05 Sanofi Sa Utilisation d'un antagoniste de l'angiotensine ii et d'un derive du benzofurane pour la preparation d'un medicament utile dans le traitement des affections cardiovasculaires
GB9613470D0 (en) * 1996-06-27 1996-08-28 Ciba Geigy Ag Small solid oral dosage form
JP2011123241A (ja) * 2009-12-10 2011-06-23 Canon Inc 撮影システム

Also Published As

Publication number Publication date
EP2055301A1 (en) 2009-05-06
JP2012051948A (ja) 2012-03-15
CN1133427C (zh) 2004-01-07
PT1410797E (pt) 2007-12-03
HUP0203374A2 (hu) 2004-05-28
ES2231873T3 (es) 2005-05-16
ATE371449T1 (de) 2007-09-15
EP1410797B1 (en) 2007-08-29
NZ524346A (en) 2004-09-24
DE69730834D1 (de) 2004-10-28
EP1410797A1 (en) 2004-04-21
DE69739642D1 (de) 2009-12-10
KR20060079260A (ko) 2006-07-05
MY123149A (en) 2006-05-31
NZ333385A (en) 2000-09-29
KR20090099020A (ko) 2009-09-18
CA2259148A1 (en) 1997-12-31
AU724998B2 (en) 2000-10-05
AR008618A1 (es) 2000-02-09
CN1475207B (zh) 2010-09-29
HK1019858A1 (en) 2000-06-09
RU2009115778A (ru) 2010-11-10
EP0914119B1 (en) 2004-09-22
AR059324A2 (es) 2008-03-26
US6294197B1 (en) 2001-09-25
WO1997049394A3 (en) 2001-12-20
ES2290400T3 (es) 2008-02-16
CZ426998A3 (cs) 1999-03-17
ID17553A (id) 1998-01-08
KR100618038B1 (ko) 2006-11-30
BR9709956A (pt) 1999-08-10
US6485745B1 (en) 2002-11-26
US20030035832A1 (en) 2003-02-20
EP1767206A3 (en) 2007-04-18
EP1767207A3 (en) 2007-04-18
KR20000022111A (ko) 2000-04-25
CA2673462A1 (en) 1997-12-31
CA2259148C (en) 2009-09-29
RU2453306C2 (ru) 2012-06-20
KR101208430B1 (ko) 2012-12-05
ZA975673B (en) 1997-12-29
NO331739B1 (no) 2012-03-12
CN1951372A (zh) 2007-04-25
PE87498A1 (es) 1998-12-21
EP1767206B1 (en) 2009-10-28
WO1997049394A2 (en) 1997-12-31
DK0914119T3 (da) 2005-01-31
MY156312A (en) 2016-01-29
CN1475207A (zh) 2004-02-18
NO20041287L (no) 2004-03-26
NO986056L (no) 1998-12-22
JP4969338B2 (ja) 2012-07-04
HK1060700A1 (en) 2004-08-20
PL188271B1 (pl) 2005-01-31
RU2203054C2 (ru) 2003-04-27
PT914119E (pt) 2005-02-28
EP1776953A1 (en) 2007-04-25
TR199802698T2 (xx) 1999-04-21
TW473394B (en) 2002-01-21
EP0914119A2 (en) 1999-05-12
JP2000506540A (ja) 2000-05-30
CZ296850B6 (cs) 2006-07-12
DE69738089T2 (de) 2008-05-21
DK1410797T3 (da) 2007-10-15
PL330709A1 (en) 1999-05-24
JP2003231634A (ja) 2003-08-19
EP1767206A2 (en) 2007-03-28
EP1774967A1 (en) 2007-04-18
CA2673462C (en) 2011-10-04
GB9613470D0 (en) 1996-08-28
KR20110063587A (ko) 2011-06-10
SK285902B6 (sk) 2007-10-04
EP1767207A2 (en) 2007-03-28
JP2014012747A (ja) 2014-01-23
AU3340297A (en) 1998-01-14
NO317181B1 (no) 2004-09-06
CY2553B1 (en) 2008-07-02
RU2007100200A (ru) 2008-07-20
CN1232394A (zh) 1999-10-20
KR20080014149A (ko) 2008-02-13
KR101161283B1 (ko) 2012-07-02
SI1410797T1 (sl) 2008-08-31
EP0914119A3 (en) 2002-03-06
IL195339A0 (en) 2009-08-03
ATE276750T1 (de) 2004-10-15
RU2013113610A (ru) 2014-10-10
PT1767206E (pt) 2010-01-27
US6858228B2 (en) 2005-02-22
DE69738089D1 (de) 2007-10-11
HU229134B1 (en) 2013-08-28
KR20050092054A (ko) 2005-09-16
SI0914119T1 (en) 2005-04-30
JP2007238637A (ja) 2007-09-20
HUP0203374A3 (en) 2004-06-28
CO4870755A1 (es) 1999-12-27
SK178498A3 (en) 1999-06-11
KR100792389B1 (ko) 2008-01-08
RU2294743C2 (ru) 2007-03-10
ATE446749T1 (de) 2009-11-15
PL188233B1 (pl) 2004-12-31
NO986056D0 (no) 1998-12-22
MY146868A (en) 2012-09-28
DK1767206T3 (da) 2010-01-25
CN1951372B (zh) 2011-03-23
DE69730834T2 (de) 2005-10-06
ES2335683T3 (es) 2010-03-31

Similar Documents

Publication Publication Date Title
IL195339A0 (en) Solid oral dosage forms of valsartan
HUP9903407A3 (en) Oral pharmaceutical preparation containing ibandronat
HUP9901454A3 (en) Dosage form of ibuprofen
EP1020193A4 (en) ORAL PREPARATION
EG24077A (en) Oral 2-methyl-thieno-benzodiazepine formulation
HUP9603064A2 (en) New oral pharmaceutical dosage form
HUP9802913A3 (en) Bioadhesive solid dosage form
IL110014A0 (en) Solid controlled-release oral dosage forms
PL341428A1 (en) Oral pharmacological dosage form of prolonged release type
HUP0003757A3 (en) Oral pharmaceutical compositions of levosimendan
IL138192A0 (en) Controlled release oral dosage forms
ZA976189B (en) Oral pharmaceutical combinations
HUP9904345A3 (en) Oral contraceptive
PL340456A1 (en) Novel oral dosage form of carvedilol
GB9600390D0 (en) Preparation of tablets
GB9618964D0 (en) Oral composition
GB9411594D0 (en) Demagnetisation of materials
AU724998C (en) Solid oral dosage forms of valsartan
ZA974125B (en) Oral pharmaceutical compositions
IL126588A0 (en) Oral dosage forms of azithromycin for improved food-compatibility
GB9617560D0 (en) Oral cleanser
GB9707576D0 (en) Enhancement of oral hygiene
GB9407647D0 (en) Oral medicament
ZA976144B (en) Oral pharmaceutical compositions
AUPN996996A0 (en) Treatment of oral conditions