IL117631A - Polysubstituted condensed di (and tri) cyclic heterocyclic compounds their production and pharmaceutical compositions containing them - Google Patents

Polysubstituted condensed di (and tri) cyclic heterocyclic compounds their production and pharmaceutical compositions containing them

Info

Publication number
IL117631A
IL117631A IL11763196A IL11763196A IL117631A IL 117631 A IL117631 A IL 117631A IL 11763196 A IL11763196 A IL 11763196A IL 11763196 A IL11763196 A IL 11763196A IL 117631 A IL117631 A IL 117631A
Authority
IL
Israel
Prior art keywords
tri
production
pharmaceutical compositions
compositions containing
heterocyclic compounds
Prior art date
Application number
IL11763196A
Other languages
English (en)
Other versions
IL117631A0 (en
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of IL117631A0 publication Critical patent/IL117631A0/xx
Publication of IL117631A publication Critical patent/IL117631A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
IL11763196A 1995-03-24 1996-03-24 Polysubstituted condensed di (and tri) cyclic heterocyclic compounds their production and pharmaceutical compositions containing them IL117631A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP9143695 1995-03-24
JP20755395 1995-07-20
JP26472795 1995-09-18
JP3003396 1996-01-23

Publications (2)

Publication Number Publication Date
IL117631A0 IL117631A0 (en) 1996-07-23
IL117631A true IL117631A (en) 2000-11-21

Family

ID=27459171

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11763196A IL117631A (en) 1995-03-24 1996-03-24 Polysubstituted condensed di (and tri) cyclic heterocyclic compounds their production and pharmaceutical compositions containing them

Country Status (17)

Country Link
US (3) US5786352A (xx)
EP (1) EP0733632B1 (xx)
KR (1) KR960034203A (xx)
CN (1) CN1140172A (xx)
AR (1) AR003937A1 (xx)
AT (1) ATE242243T1 (xx)
AU (1) AU699611B2 (xx)
BR (1) BR9601125A (xx)
CA (1) CA2172421A1 (xx)
DE (1) DE69628484T2 (xx)
ES (1) ES2194937T3 (xx)
HU (1) HUP9600732A3 (xx)
IL (1) IL117631A (xx)
MX (1) MX9601072A (xx)
NO (1) NO309272B1 (xx)
NZ (1) NZ286256A (xx)
TW (1) TW394773B (xx)

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ATE280158T1 (de) * 1999-02-24 2004-11-15 Hoffmann La Roche 3-phenylpyridinderivative und deren verwendung als nk-1 rezeptorantagonisten
US7163949B1 (en) 1999-11-03 2007-01-16 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines and use thereof
CN1414953A (zh) 1999-11-03 2003-04-30 阿尔巴尼分子研究公司 芳基和杂芳基取代的四氢异喹啉及其阻断去甲肾上腺素、多巴胺和5－羟色胺重摄取的用途
EP1103545B1 (en) * 1999-11-29 2003-11-05 F. Hoffmann-La Roche Ag 2-(3,5-Bis-trifluoromethyl-phenyl)-N-methyl-N-(6-morpholin-4-yl-4-o-tolyl-pyridin-3-yl)-isobutyramide
AU7334901A (en) 2000-07-11 2002-01-21 Du Pont Pharm Co Novel 4-phenyl substituted tetrahydroisoquinolines and therapeutic use thereof
EP1323429A4 (en) * 2000-09-26 2006-03-22 Takeda Pharmaceutical PREVENTION AND / OR REMEDY AGENTS IN RELATION TO AFFECTIVE DISORDERS
US20040058914A1 (en) * 2000-12-22 2004-03-25 Takayuki Doi Combination drugs
WO2002094799A2 (en) 2001-05-22 2002-11-28 Neurogen Corporation Melanin concentrating hormone receptor ligands: substituted 1-benzyl-4-aryl piperazine analogues
WO2003029254A1 (fr) * 2001-09-28 2003-04-10 Takeda Chemical Industries, Ltd. Procede de preparation de composes tricycliques
WO2003050123A1 (fr) * 2001-12-10 2003-06-19 Kyorin Pharmaceutical Co., Ltd. Derives bicycliques fusionnes de pyridine en tant qu'antagonistes du recepteur de la tachykinine
JP4417720B2 (ja) * 2002-01-18 2010-02-17 杏林製薬株式会社 縮合二環式ピリミジン誘導体
AU2003221204B2 (en) * 2002-03-26 2008-09-18 Kyorin Pharmaceutical Co., Ltd. Fused bicyclic pyridine derivative as tachykinin receptor antagonist
CA2514547A1 (en) 2003-01-28 2004-08-12 Takeda Pharmaceutical Company Limited Receptor agonists
TWI280239B (en) 2003-07-15 2007-05-01 Hoffmann La Roche Process for preparation of pyridine derivatives
US20060148783A1 (en) * 2003-11-10 2006-07-06 Lundeen James E Method and medicine for treating gastrointestinal disorder including fecal incontinence
US20070142367A1 (en) * 2003-11-10 2007-06-21 Lundeen James E Method and medicine for treating gastrointestinal disorder including fecal incontinence
US20050113365A1 (en) * 2003-11-10 2005-05-26 Sir Isaac Newton Enterprises Llc Method and medicine for treating gastrointestinal disorder including irritable bowel syndrome
US20060148782A1 (en) * 2003-11-10 2006-07-06 Lundeen James E Method and medicine for treating a mammal presenting urinary incontinence, urinary urgency, or both
US20060148781A1 (en) * 2003-11-10 2006-07-06 Lundeen James E Method and medicine for treating gastrointestinal disorder in a non-human mammal
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JPWO2010016552A1 (ja) * 2008-08-07 2012-01-26 武田薬品工業株式会社 過敏性腸症候群治療薬
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HUE044815T2 (hu) 2010-08-17 2019-11-28 Sirna Therapeutics Inc Hepatitisz B vírus (HBV) génexpressziójának RNS-interferencia közvetített gátlása, rövid interferáló nukleinsav (SINS) alkalmazásával
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Family Cites Families (10)

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Publication number Priority date Publication date Assignee Title
ES431307A1 (es) * 1973-11-16 1976-09-01 Thomae Gmbh Dr K Procedimiento para la preparacion de nuevos derivados de quinoleina.
DE2357253A1 (de) * 1973-11-16 1975-05-22 Thomae Gmbh Dr K Neue chinolinderivate
DE2617101A1 (de) * 1976-04-17 1977-11-17 Thomae Gmbh Dr K Neue naphthyridine
DE2638828A1 (de) * 1976-08-28 1978-03-09 Thomae Gmbh Dr K Neue thieno-pyridine
DE2722416A1 (de) * 1977-05-18 1978-11-30 Thomae Gmbh Dr K Neue thiazolo-pyridine
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TW241258B (xx) * 1992-04-15 1995-02-21 Takeda Pharm Industry Co Ltd
ATE161530T1 (de) * 1992-09-04 1998-01-15 Takeda Chemical Industries Ltd Kondensierte heterozyklische verbindungen, deren herstellung und verwendung
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TW263498B (xx) * 1993-11-10 1995-11-21 Takeda Pharm Industry Co Ltd

Also Published As

Publication number Publication date
AU4826196A (en) 1996-10-03
DE69628484D1 (de) 2003-07-10
US5786352A (en) 1998-07-28
BR9601125A (pt) 1998-01-06
ES2194937T3 (es) 2003-12-01
AU699611B2 (en) 1998-12-10
NZ286256A (en) 1999-05-28
CN1140172A (zh) 1997-01-15
KR960034203A (ko) 1996-10-22
NO961160D0 (no) 1996-03-21
NO961160L (no) 1996-09-25
HUP9600732A2 (en) 1997-03-28
US6489315B1 (en) 2002-12-03
HU9600732D0 (en) 1996-05-28
ATE242243T1 (de) 2003-06-15
IL117631A0 (en) 1996-07-23
EP0733632A1 (en) 1996-09-25
EP0733632B1 (en) 2003-06-04
DE69628484T2 (de) 2004-05-19
US6147071A (en) 2000-11-14
MX9601072A (es) 1997-03-29
AR003937A1 (es) 1998-09-30
CA2172421A1 (en) 1996-09-25
HUP9600732A3 (en) 2000-03-28
NO309272B1 (no) 2001-01-08
TW394773B (en) 2000-06-21

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