IL117078A - Substituted benzenesulfonylureas and-thioureas, processes for their preparation, their use for the production of pharmaceutical preparations, and pharmaceutical preparations containing them - Google Patents

Substituted benzenesulfonylureas and-thioureas, processes for their preparation, their use for the production of pharmaceutical preparations, and pharmaceutical preparations containing them

Info

Publication number
IL117078A
IL117078A IL11707896A IL11707896A IL117078A IL 117078 A IL117078 A IL 117078A IL 11707896 A IL11707896 A IL 11707896A IL 11707896 A IL11707896 A IL 11707896A IL 117078 A IL117078 A IL 117078A
Authority
IL
Israel
Prior art keywords
pharmaceutical preparations
thioureas
processes
preparation
production
Prior art date
Application number
IL11707896A
Other languages
English (en)
Other versions
IL117078A0 (en
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of IL117078A0 publication Critical patent/IL117078A0/xx
Publication of IL117078A publication Critical patent/IL117078A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/40—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of thiourea or isothiourea groups further bound to other hetero atoms
    • C07C335/42—Sulfonylthioureas; Sulfonylisothioureas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/52—Y being a hetero atom
    • C07C311/54—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea
    • C07C311/57—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/58—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings having nitrogen atoms of the sulfonylurea groups bound to hydrogen atoms or to acyclic carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Furan Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyridine Compounds (AREA)
IL11707896A 1995-02-10 1996-02-08 Substituted benzenesulfonylureas and-thioureas, processes for their preparation, their use for the production of pharmaceutical preparations, and pharmaceutical preparations containing them IL117078A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19504379A DE19504379A1 (de) 1995-02-10 1995-02-10 Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung pharmazeutischer Präparate sowie sie enthaltende pharmazeutische Präparate

Publications (2)

Publication Number Publication Date
IL117078A0 IL117078A0 (en) 1996-06-18
IL117078A true IL117078A (en) 2001-01-11

Family

ID=7753608

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11707896A IL117078A (en) 1995-02-10 1996-02-08 Substituted benzenesulfonylureas and-thioureas, processes for their preparation, their use for the production of pharmaceutical preparations, and pharmaceutical preparations containing them

Country Status (30)

Country Link
US (1) US5607976A (hr)
EP (1) EP0726250B1 (hr)
JP (1) JP3774773B2 (hr)
KR (1) KR100446565B1 (hr)
CN (1) CN1064041C (hr)
AR (1) AR001082A1 (hr)
AT (1) ATE197291T1 (hr)
AU (1) AU700883B2 (hr)
BR (1) BR9600370A (hr)
CA (1) CA2169219C (hr)
CZ (1) CZ290809B6 (hr)
DE (2) DE19504379A1 (hr)
DK (1) DK0726250T3 (hr)
ES (1) ES2152440T3 (hr)
FI (1) FI120394B (hr)
GR (1) GR3034886T3 (hr)
HR (1) HRP960063B1 (hr)
HU (1) HU224211B1 (hr)
IL (1) IL117078A (hr)
MY (1) MY114693A (hr)
NO (1) NO305750B1 (hr)
NZ (1) NZ280954A (hr)
PL (1) PL181656B1 (hr)
PT (1) PT726250E (hr)
RU (1) RU2155750C2 (hr)
SI (1) SI9600040B (hr)
SK (1) SK281357B6 (hr)
TR (1) TR199600747A2 (hr)
TW (1) TW419457B (hr)
ZA (1) ZA961050B (hr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19832009A1 (de) 1998-07-16 2000-01-20 Hoechst Marion Roussel De Gmbh 2,5-Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende pharamazeutische Präparate
DE19858253A1 (de) * 1998-12-17 2000-06-21 Aventis Pharma Gmbh Verwendung von Inhibitoren des KQt1-Kanals zur Herstellung eines Medikaments zur Behandlung von Krankheiten, die durch Helminthen und Ektoparasiten hervorgerufen werden
DE10060809A1 (de) * 2000-12-07 2002-06-20 Aventis Pharma Gmbh Substituierte Anthranilsäuren, ihre Verwendung als Medikament oder Diagnostikum, sowie sie enthaltendes Medikament, sowie ein pharmazeutisches Kombinationspräparat mit einem Natrium/Wasserstoff-Austausch (NHE)-Blocker
DE10129704A1 (de) * 2001-06-22 2003-01-02 Aventis Pharma Gmbh Verwendung von Benzolsulfonyl(thio)harnstoffen in der Behandlung des septischen Schocks
CN1330630C (zh) * 2004-03-10 2007-08-08 中国药科大学 新的磺酰(硫)脲衍生物、其制备方法及含有它们的药物组合物
UA87854C2 (en) * 2004-06-07 2009-08-25 Мерк Энд Ко., Инк. N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators
MX2008013238A (es) * 2006-04-12 2008-10-21 Merck & Co Inc Antagonistas de los canales de calcio de tipo t de piridil amida.
JP5524071B2 (ja) * 2007-10-24 2014-06-18 メルク・シャープ・アンド・ドーム・コーポレーション 複素環フェニルアミドｔ型カルシウムチャネルアンタゴニスト

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE243821C (hr) *
DE1493672C3 (de) * 1964-08-01 1974-05-02 Farbwerke Hoechst Ag, Vormals Meister Lucius & Bruening, 6000 Frankfurt Verfahren zur Herstellung von Benzolsulfonylharnstoffen
DE1518874C3 (de) * 1964-10-07 1975-03-13 Farbwerke Hoechst Ag, Vormals Meister Lucius & Bruening, 6000 Frankfurt Benzolsulfonylharnstoffe und Verfahren zu ihrer Herstellung
DE1443919C3 (de) * 1964-12-28 1973-11-29 Farbwerke Hoechst Ag, Vormals Meister Lucius & Bruening, 6000 Frankfurt Benzolsulfonylharnstoffe, Ver fahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitun gen
US3917690A (en) * 1966-11-29 1975-11-04 Hoechst Ag Benzenesulfonyl ureas and process for their manufacture
DE1568648C3 (de) * 1966-12-19 1975-03-27 Farbwerke Hoechst Ag, Vormals Meister Lucius & Bruening, 6000 Frankfurt Benzolsulfonylharnstoffe, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
BE754454A (fr) * 1969-08-06 1971-02-05 Bayer Ag Nouveaux composes hypoglycemiques du type d'arylsulfonylurees et d'arylsulfonylsemicarbazides contenant des groupes carbonamide
DE2413514C3 (de) * 1974-03-21 1982-03-04 Hoechst Ag, 6000 Frankfurt N-Acylaminoathylbenzolsulfonyl-N'-methylharnstoffe, Verfahren zu ihrer Herstellung und deren Verwendung
DE3011153A1 (de) * 1980-03-22 1981-10-15 Hoechst Ag, 6000 Frankfurt Verwendung von n-(4- spitze klammer auf 2-(5-chlor-2-methoxy-benzamido)-aethylspitze klammer zu -benzolsulfonyl)-n'-methyl-harnstoff
US5215985A (en) * 1990-07-20 1993-06-01 E. R. Squibb & Sons, Inc. Method for treating ischemic insult to neurons employing an ATP-sensitive potassium channel blocker
ES2098069T3 (es) * 1993-02-23 1997-04-16 Hoechst Ag Bencenosulfonil-ureas y -tioureas sustituidas, procedimiento para su preparacion y su utilizacion como agentes farmaceuticos.

Also Published As

Publication number Publication date
RU2155750C2 (ru) 2000-09-10
SK17596A3 (en) 1996-10-02
NO960529D0 (no) 1996-02-09
NO305750B1 (no) 1999-07-19
DE59606062D1 (de) 2000-12-07
BR9600370A (pt) 1998-03-03
NZ280954A (en) 1996-10-28
HRP960063B1 (en) 2001-08-31
PL181656B1 (pl) 2001-08-31
EP0726250B1 (de) 2000-11-02
CZ38296A3 (en) 1996-08-14
KR100446565B1 (ko) 2004-12-03
JPH08245553A (ja) 1996-09-24
DK0726250T3 (da) 2001-01-08
SK281357B6 (sk) 2001-02-12
NO960529L (no) 1996-08-12
SI9600040A (en) 1996-10-31
HRP960063A2 (en) 1997-10-31
CZ290809B6 (cs) 2002-10-16
HU9503932D0 (en) 1996-03-28
CN1064041C (zh) 2001-04-04
ES2152440T3 (es) 2001-02-01
KR960031431A (ko) 1996-09-17
PL312531A1 (en) 1996-08-19
CA2169219A1 (en) 1996-08-11
GR3034886T3 (en) 2001-02-28
MY114693A (en) 2002-12-31
FI960587A (fi) 1996-08-11
AR001082A1 (es) 1997-09-24
AU4442996A (en) 1996-08-22
CN1137519A (zh) 1996-12-11
FI960587A0 (fi) 1996-02-08
IL117078A0 (en) 1996-06-18
FI120394B (fi) 2009-10-15
PT726250E (pt) 2001-03-30
HUT73975A (en) 1996-10-28
US5607976A (en) 1997-03-04
DE19504379A1 (de) 1996-08-14
TW419457B (en) 2001-01-21
JP3774773B2 (ja) 2006-05-17
ZA961050B (en) 1996-08-29
SI9600040B (en) 2001-12-31
HU224211B1 (hu) 2005-06-28
AU700883B2 (en) 1999-01-14
CA2169219C (en) 2009-01-06
TR199600747A2 (tr) 1996-08-21
EP0726250A1 (de) 1996-08-14
ATE197291T1 (de) 2000-11-15

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees