IL115914A - Safam's crystalline crystallization salts, the process for their preparation and the pharmaceutical preparations containing them - Google Patents

Safam's crystalline crystallization salts, the process for their preparation and the pharmaceutical preparations containing them

Info

Publication number
IL115914A
IL115914A IL11591495A IL11591495A IL115914A IL 115914 A IL115914 A IL 115914A IL 11591495 A IL11591495 A IL 11591495A IL 11591495 A IL11591495 A IL 11591495A IL 115914 A IL115914 A IL 115914A
Authority
IL
Israel
Prior art keywords
formula
acid
acids
anion
compound
Prior art date
Application number
IL11591495A
Other languages
English (en)
Hebrew (he)
Other versions
IL115914A0 (en
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of IL115914A0 publication Critical patent/IL115914A0/xx
Publication of IL115914A publication Critical patent/IL115914A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/48—Methylene radicals, substituted by hetero rings
    • C07D501/56—Methylene radicals, substituted by hetero rings with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL11591495A 1994-11-10 1995-11-08 Safam's crystalline crystallization salts, the process for their preparation and the pharmaceutical preparations containing them IL115914A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4440141A DE4440141A1 (de) 1994-11-10 1994-11-10 Neue kristalline Cephem-Säureadditionssalze und Verfahren zu ihrer Herstellung

Publications (2)

Publication Number Publication Date
IL115914A0 IL115914A0 (en) 1996-01-31
IL115914A true IL115914A (en) 2002-08-14

Family

ID=6532953

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11591495A IL115914A (en) 1994-11-10 1995-11-08 Safam's crystalline crystallization salts, the process for their preparation and the pharmaceutical preparations containing them

Country Status (28)

Country Link
US (1) US5747484A (ko)
EP (1) EP0711774B1 (ko)
JP (1) JP3920939B2 (ko)
KR (1) KR100449191B1 (ko)
CN (1) CN1066452C (ko)
AR (1) AR002246A1 (ko)
AT (1) ATE213248T1 (ko)
AU (1) AU707730B2 (ko)
BR (1) BR9505132A (ko)
CA (1) CA2162530C (ko)
CZ (1) CZ290936B6 (ko)
DE (2) DE4440141A1 (ko)
DK (1) DK0711774T3 (ko)
ES (1) ES2172549T3 (ko)
FI (1) FI120263B (ko)
HU (1) HU219475B (ko)
IL (1) IL115914A (ko)
MA (1) MA23709A1 (ko)
NO (1) NO311891B1 (ko)
NZ (1) NZ280424A (ko)
OA (1) OA10242A (ko)
PL (1) PL182806B1 (ko)
PT (1) PT711774E (ko)
RU (1) RU2161619C2 (ko)
SK (1) SK282545B6 (ko)
TR (1) TR199501392A2 (ko)
TW (1) TW422847B (ko)
ZA (1) ZA959510B (ko)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2288199A1 (en) * 1997-04-29 1998-11-05 The University Of New Mexico Hydroxynaphthoic acids and derivatives
MXPA05004219A (es) * 2002-10-25 2005-06-08 Akzo Nobel Nv Composicion farmaceutica de liberacion prolongada.
EP1945223B1 (en) * 2005-10-29 2010-07-07 Intervet International BV Cefquinome compositions and methods of their use
TWI400243B (zh) * 2009-07-20 2013-07-01 Intervet Int Bv 製造西喹諾（ｃｅｆｑｕｉｎｏｍｅ）粒子的方法
EP3616695A1 (en) 2011-09-09 2020-03-04 Merck Sharp & Dohme Corp. Methods for treating intrapulmonary infections
EP2750706A4 (en) * 2011-09-29 2015-04-15 Alere San Diego Inc 2-HYDROXYHIPPURIC ACID ANALOGUES AND METHODS FOR THEIR SYNTHESIS AND USE
US8809314B1 (en) 2012-09-07 2014-08-19 Cubist Pharmacueticals, Inc. Cephalosporin compound
US8476425B1 (en) 2012-09-27 2013-07-02 Cubist Pharmaceuticals, Inc. Tazobactam arginine compositions
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
KR102329764B1 (ko) 2013-03-15 2021-11-23 머크 샤프 앤드 돔 코포레이션 세프톨로잔 항균성 조성물
US20140274991A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Ceftolozane pharmaceutical compositions
EP3043797B1 (en) 2013-09-09 2020-04-08 Merck Sharp & Dohme Corp. Treating infections with ceftolozane/tazobactam in subjects having impaired renal function
US20150094293A1 (en) 2013-09-27 2015-04-02 Calixa Therapeutics, Inc. Solid forms of ceftolozane

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3118732A1 (de) * 1981-05-12 1982-12-02 Hoechst Ag, 6000 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
DE3248281A1 (de) * 1982-12-28 1984-06-28 Hoechst Ag, 6230 Frankfurt Kristalisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung
DE3316797A1 (de) * 1983-05-07 1984-11-08 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von cephemverbindungen
DE3706020A1 (de) * 1987-02-25 1988-09-08 Hoechst Ag Kristallisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
CA2162530A1 (en) 1996-05-11
DE59510048D1 (de) 2002-03-21
AU3772895A (en) 1996-05-16
US5747484A (en) 1998-05-05
MA23709A1 (fr) 1996-07-01
CZ293395A3 (en) 1996-05-15
RU2161619C2 (ru) 2001-01-10
HU219475B (hu) 2001-04-28
CA2162530C (en) 2007-07-31
ATE213248T1 (de) 2002-02-15
DK0711774T3 (da) 2002-04-22
KR100449191B1 (ko) 2006-01-12
FI955382A (fi) 1996-05-11
TR199501392A2 (tr) 1996-07-21
NZ280424A (en) 1997-06-24
OA10242A (fr) 1997-09-19
EP0711774A1 (de) 1996-05-15
ZA959510B (en) 1996-05-28
NO311891B1 (no) 2002-02-11
FI955382A0 (fi) 1995-11-08
DE4440141A1 (de) 1996-05-15
PL182806B1 (pl) 2002-03-29
IL115914A0 (en) 1996-01-31
ES2172549T3 (es) 2002-10-01
AU707730B2 (en) 1999-07-15
SK282545B6 (sk) 2002-10-08
AR002246A1 (es) 1998-03-11
JP3920939B2 (ja) 2007-05-30
FI120263B (fi) 2009-08-31
CN1129220A (zh) 1996-08-21
PT711774E (pt) 2002-07-31
CN1066452C (zh) 2001-05-30
TW422847B (en) 2001-02-21
HUT74163A (en) 1996-11-28
KR960017670A (ko) 1996-06-17
HU9503213D0 (en) 1996-01-29
NO954511L (no) 1996-05-13
SK139795A3 (en) 1996-06-05
JPH08208662A (ja) 1996-08-13
CZ290936B6 (cs) 2002-11-13
EP0711774B1 (de) 2002-02-13
BR9505132A (pt) 1997-09-09
NO954511D0 (no) 1995-11-09
PL311326A1 (en) 1996-05-13

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