DK0711774T3 - Nye krystallinske cephem-syreadditionssalte og fremgangsmåder til deres fremstilling - Google Patents

Nye krystallinske cephem-syreadditionssalte og fremgangsmåder til deres fremstilling

Info

Publication number
DK0711774T3
DK0711774T3 DK95117409T DK95117409T DK0711774T3 DK 0711774 T3 DK0711774 T3 DK 0711774T3 DK 95117409 T DK95117409 T DK 95117409T DK 95117409 T DK95117409 T DK 95117409T DK 0711774 T3 DK0711774 T3 DK 0711774T3
Authority
DK
Denmark
Prior art keywords
processes
preparation
acid addition
addition salts
new crystalline
Prior art date
Application number
DK95117409T
Other languages
English (en)
Inventor
Walter Dr Duerckheimer
Rudolf Dr Lattrell
Peter Dr Schmid
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Application granted granted Critical
Publication of DK0711774T3 publication Critical patent/DK0711774T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/48—Methylene radicals, substituted by hetero rings
    • C07D501/56—Methylene radicals, substituted by hetero rings with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK95117409T 1994-11-10 1995-11-06 Nye krystallinske cephem-syreadditionssalte og fremgangsmåder til deres fremstilling DK0711774T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4440141A DE4440141A1 (de) 1994-11-10 1994-11-10 Neue kristalline Cephem-Säureadditionssalze und Verfahren zu ihrer Herstellung

Publications (1)

Publication Number Publication Date
DK0711774T3 true DK0711774T3 (da) 2002-04-22

Family

ID=6532953

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95117409T DK0711774T3 (da) 1994-11-10 1995-11-06 Nye krystallinske cephem-syreadditionssalte og fremgangsmåder til deres fremstilling

Country Status (28)

Country Link
US (1) US5747484A (da)
EP (1) EP0711774B1 (da)
JP (1) JP3920939B2 (da)
KR (1) KR100449191B1 (da)
CN (1) CN1066452C (da)
AR (1) AR002246A1 (da)
AT (1) ATE213248T1 (da)
AU (1) AU707730B2 (da)
BR (1) BR9505132A (da)
CA (1) CA2162530C (da)
CZ (1) CZ290936B6 (da)
DE (2) DE4440141A1 (da)
DK (1) DK0711774T3 (da)
ES (1) ES2172549T3 (da)
FI (1) FI120263B (da)
HU (1) HU219475B (da)
IL (1) IL115914A (da)
MA (1) MA23709A1 (da)
NO (1) NO311891B1 (da)
NZ (1) NZ280424A (da)
OA (1) OA10242A (da)
PL (1) PL182806B1 (da)
PT (1) PT711774E (da)
RU (1) RU2161619C2 (da)
SK (1) SK282545B6 (da)
TR (1) TR199501392A2 (da)
TW (1) TW422847B (da)
ZA (1) ZA959510B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998049130A2 (en) * 1997-04-29 1998-11-05 The University Of New Mexico Hydroxynaphthoic acids and derivatives
JP4584715B2 (ja) * 2002-10-25 2010-11-24 インターベツト・インターナシヨナル・ベー・ベー 持続放出性医薬組成物
PT1945223E (pt) * 2005-10-29 2010-10-14 Intervet Int Bv Composições de cefquinoma e métodos para a sua utilização
TWI400243B (zh) * 2009-07-20 2013-07-01 Intervet Int Bv 製造西喹諾（ｃｅｆｑｕｉｎｏｍｅ）粒子的方法
MX352760B (es) 2011-09-09 2017-12-07 Merck Sharp & Dohme Corp Star Metodos para tratar infecciones intrapulmonares.
EP2750706A4 (en) * 2011-09-29 2015-04-15 Alere San Diego Inc 2-HYDROXYHIPPURIC ACID ANALOGUES AND METHODS FOR THEIR SYNTHESIS AND USE
US8809314B1 (en) 2012-09-07 2014-08-19 Cubist Pharmacueticals, Inc. Cephalosporin compound
US8476425B1 (en) 2012-09-27 2013-07-02 Cubist Pharmaceuticals, Inc. Tazobactam arginine compositions
US20140275000A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Ceftolozane pharmaceutical compositions
MX2020004205A (es) 2013-03-15 2021-11-16 Merck Sharp & Dohme Llc Composiciones antibioticas de ceftolozano.
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
WO2015035376A2 (en) 2013-09-09 2015-03-12 Calixa Therapeutics, Inc. Treating infections with ceftolozane/tazobactam in subjects having impaired renal function
US20150094293A1 (en) 2013-09-27 2015-04-02 Calixa Therapeutics, Inc. Solid forms of ceftolozane

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3118732A1 (de) * 1981-05-12 1982-12-02 Hoechst Ag, 6000 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
DE3248281A1 (de) * 1982-12-28 1984-06-28 Hoechst Ag, 6230 Frankfurt Kristalisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung
DE3316797A1 (de) * 1983-05-07 1984-11-08 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von cephemverbindungen
DE3706020A1 (de) * 1987-02-25 1988-09-08 Hoechst Ag Kristallisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
IL115914A (en) 2002-08-14
EP0711774A1 (de) 1996-05-15
CN1066452C (zh) 2001-05-30
PL311326A1 (en) 1996-05-13
ES2172549T3 (es) 2002-10-01
US5747484A (en) 1998-05-05
DE59510048D1 (de) 2002-03-21
KR100449191B1 (ko) 2006-01-12
NO954511L (no) 1996-05-13
HU219475B (hu) 2001-04-28
NZ280424A (en) 1997-06-24
CZ290936B6 (cs) 2002-11-13
ZA959510B (en) 1996-05-28
SK282545B6 (sk) 2002-10-08
TR199501392A2 (tr) 1996-07-21
JP3920939B2 (ja) 2007-05-30
ATE213248T1 (de) 2002-02-15
DE4440141A1 (de) 1996-05-15
JPH08208662A (ja) 1996-08-13
HU9503213D0 (en) 1996-01-29
NO954511D0 (no) 1995-11-09
BR9505132A (pt) 1997-09-09
CA2162530A1 (en) 1996-05-11
CA2162530C (en) 2007-07-31
RU2161619C2 (ru) 2001-01-10
CZ293395A3 (en) 1996-05-15
SK139795A3 (en) 1996-06-05
EP0711774B1 (de) 2002-02-13
FI955382A0 (fi) 1995-11-08
FI955382A (fi) 1996-05-11
AU707730B2 (en) 1999-07-15
AR002246A1 (es) 1998-03-11
CN1129220A (zh) 1996-08-21
HUT74163A (en) 1996-11-28
KR960017670A (ko) 1996-06-17
OA10242A (fr) 1997-09-19
TW422847B (en) 2001-02-21
IL115914A0 (en) 1996-01-31
FI120263B (fi) 2009-08-31
PT711774E (pt) 2002-07-31
PL182806B1 (pl) 2002-03-29
NO311891B1 (no) 2002-02-11
AU3772895A (en) 1996-05-16
MA23709A1 (fr) 1996-07-01

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