DK491385A - 1,2,4-triazolocarbamater og deres syreadditionssalte, fremgangsmaader til deres fremstilling og laegemidler indeholdende saadanne forbindelser - Google Patents

1,2,4-triazolocarbamater og deres syreadditionssalte, fremgangsmaader til deres fremstilling og laegemidler indeholdende saadanne forbindelser Download PDF

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Publication number
DK491385A
DK491385A DK491385A DK491385A DK491385A DK 491385 A DK491385 A DK 491385A DK 491385 A DK491385 A DK 491385A DK 491385 A DK491385 A DK 491385A DK 491385 A DK491385 A DK 491385A
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Denmark
Prior art keywords
triazolocarbamates
procedures
compounds
preparation
acid addition
Prior art date
Application number
DK491385A
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English (en)
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DK491385D0 (da
Inventor
Karl-Heinz Weber
Dieter Hinzen
Franz Josef Kuhn
Erich Lehr
Wilhelm Froelke
Wolfgang Troeger
Helmut Ensinger
Gerhard Walther
Albrecht Harreus
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of DK491385D0 publication Critical patent/DK491385D0/da
Publication of DK491385A publication Critical patent/DK491385A/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/74Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/101,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12Oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK491385A 1984-10-27 1985-10-25 1,2,4-triazolocarbamater og deres syreadditionssalte, fremgangsmaader til deres fremstilling og laegemidler indeholdende saadanne forbindelser DK491385A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843439450 DE3439450A1 (de) 1984-10-27 1984-10-27 1,2,4-triazolo-carbamate und ihre saeureadditionssalze, verfahren zu ihrer herstellung und arzneimittel

Publications (2)

Publication Number Publication Date
DK491385D0 DK491385D0 (da) 1985-10-25
DK491385A true DK491385A (da) 1986-04-28

Family

ID=6248953

Family Applications (1)

Application Number Title Priority Date Filing Date
DK491385A DK491385A (da) 1984-10-27 1985-10-25 1,2,4-triazolocarbamater og deres syreadditionssalte, fremgangsmaader til deres fremstilling og laegemidler indeholdende saadanne forbindelser

Country Status (22)

Country Link
US (1) US4732900A (da)
EP (1) EP0180115A3 (da)
JP (1) JPS61103876A (da)
KR (1) KR860003240A (da)
AU (1) AU576393B2 (da)
CA (1) CA1244030A (da)
CS (2) CS255897B2 (da)
DD (1) DD236928A5 (da)
DE (1) DE3439450A1 (da)
DK (1) DK491385A (da)
ES (2) ES8701738A1 (da)
FI (1) FI854178L (da)
GR (1) GR852581B (da)
HU (1) HU193351B (da)
IL (1) IL76823A0 (da)
NO (1) NO854276L (da)
NZ (1) NZ213969A (da)
PH (1) PH22446A (da)
PL (2) PL255940A1 (da)
PT (1) PT81370B (da)
SU (2) SU1436873A3 (da)
ZA (1) ZA858195B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2784921B2 (ja) * 1988-03-23 1998-08-13 武田薬品工業株式会社 カルバメート化合物
US5100906A (en) * 1990-04-19 1992-03-31 Merrell Dow Pharmaceuticals Inc. 5-aryl-4-alkyl-3h-1,2,4-triazole-3-thiones useful as memory enhancers
US5331002A (en) * 1990-04-19 1994-07-19 Merrell Dow Pharmaceuticals Inc. 5-aryl-4-alkyl-3H-1,2,4-triazole-3-thiones useful as memory enhancers
US5728834A (en) * 1996-11-14 1998-03-17 Wyckoff Chemical Company, Inc. Process for preparation of 4-aryl-1,2,4-triazol-3-ones
BRPI0509172A (pt) * 2004-03-26 2007-08-28 Amphora Discovery Corp pelo menos uma entidade quìmica, composição farmacêutica, métodos para tratar um paciente, para inibir pelo menos uma enzima que utiliza atp, e para tratar pelo menos uma doença, uso de pelo menos uma entidade quìmica, e, método para a fabricação de um medicamento
WO2006074445A2 (en) * 2005-01-10 2006-07-13 Alexandros Makriyannis Novel heteropyrrole analogs acting on cannabiniod receptors
US8853205B2 (en) 2005-01-10 2014-10-07 University Of Connecticut Heteropyrrole analogs acting on cannabinoid receptors
US10053444B2 (en) 2009-02-19 2018-08-21 University Of Connecticut Cannabinergic nitrate esters and related analogs
CA3125847A1 (en) 2020-07-27 2022-01-27 Makscientific, Llc Process for making biologically active compounds and intermediates thereof
US12054480B2 (en) 2020-07-31 2024-08-06 Makscientific, Llc Compounds for treating cannabinoid toxicity and acute cannabinoid overdose
CN115991698B (zh) * 2022-11-03 2024-03-29 广东中科药物研究有限公司 一种杂环化合物及其制备方法与应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB681376A (en) * 1949-11-23 1952-10-22 Geigy Ag J R Manufacture of heterocyclic carbamic acid derivatives and their use as agents for combating pests
NL7112373A (da) * 1970-09-25 1972-03-28
US4209515A (en) * 1974-06-14 1980-06-24 Ciba-Geigy Corporation Triazole derivatives
US4160839A (en) * 1976-03-01 1979-07-10 Gulf Oil Corporation Carbamyltriazole insecticides
JPS59199681A (ja) * 1983-04-26 1984-11-12 Ube Ind Ltd 1,2,4−トリアゾ−ル−3−カルボン酸アミド類の製造法
FI850994L (fi) * 1984-03-16 1985-09-17 Ciba Geigy Ag Foerfarande foer framstaellning av nya 1,2,4-triazacykloalkadienderivat.
US4610717A (en) * 1985-11-26 1986-09-09 Shell Oil Company Certain 5-(R-oxy)-1-phenyl or (3-(trifluoromethyl)phenyl)triazoles, useful for controlling undesired plant growth

Also Published As

Publication number Publication date
ES548206A0 (es) 1986-12-01
DK491385D0 (da) 1985-10-25
CS255877B2 (en) 1988-03-15
CA1244030A (en) 1988-11-01
SU1436873A3 (ru) 1988-11-07
PL255940A1 (en) 1987-07-13
FI854178L (fi) 1986-04-28
NZ213969A (en) 1987-11-27
PT81370A (de) 1985-11-01
EP0180115A2 (de) 1986-05-07
KR860003240A (ko) 1986-05-21
CS255897B2 (en) 1988-03-15
US4732900A (en) 1988-03-22
ES554373A0 (es) 1987-04-01
FI854178A0 (fi) 1985-10-25
HU193351B (en) 1987-09-28
PL264492A1 (en) 1987-11-30
AU4909485A (en) 1986-05-01
DD236928A5 (de) 1986-06-25
ES8701738A1 (es) 1986-12-01
GR852581B (da) 1986-02-26
EP0180115A3 (de) 1987-01-21
ZA858195B (en) 1987-06-24
IL76823A0 (en) 1986-02-28
SU1429934A3 (ru) 1988-10-07
NO854276L (no) 1986-04-28
ES8704468A1 (es) 1987-04-01
HUT40091A (en) 1986-11-28
PH22446A (en) 1988-09-12
AU576393B2 (en) 1988-08-25
JPS61103876A (ja) 1986-05-22
PT81370B (de) 1987-08-20
DE3439450A1 (de) 1986-05-07

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