IL114785A - 1,3-dioxo-6-) 3-aminopropyl (-4-heteroaryl-1,2,3,6-tetrahydro-pyrrolo] C-3,4 [carbazoles, their preparation and pharmaceutical preparations containing them - Google Patents

1,3-dioxo-6-) 3-aminopropyl (-4-heteroaryl-1,2,3,6-tetrahydro-pyrrolo] C-3,4 [carbazoles, their preparation and pharmaceutical preparations containing them

Info

Publication number
IL114785A
IL114785A IL114785A IL11478595A IL114785A IL 114785 A IL114785 A IL 114785A IL 114785 A IL114785 A IL 114785A IL 11478595 A IL11478595 A IL 11478595A IL 114785 A IL114785 A IL 114785A
Authority
IL
Israel
Prior art keywords
formula
compound
compounds
hydrogen
pharmaceutically acceptable
Prior art date
Application number
IL114785A
Other languages
English (en)
Hebrew (he)
Other versions
IL114785A0 (en
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IL114785A0 publication Critical patent/IL114785A0/xx
Publication of IL114785A publication Critical patent/IL114785A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Steroid Compounds (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL114785A 1994-08-04 1995-07-31 1,3-dioxo-6-) 3-aminopropyl (-4-heteroaryl-1,2,3,6-tetrahydro-pyrrolo] C-3,4 [carbazoles, their preparation and pharmaceutical preparations containing them IL114785A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28604394A 1994-08-04 1994-08-04

Publications (2)

Publication Number Publication Date
IL114785A0 IL114785A0 (en) 1995-11-27
IL114785A true IL114785A (en) 1998-06-15

Family

ID=23096813

Family Applications (1)

Application Number Title Priority Date Filing Date
IL114785A IL114785A (en) 1994-08-04 1995-07-31 1,3-dioxo-6-) 3-aminopropyl (-4-heteroaryl-1,2,3,6-tetrahydro-pyrrolo] C-3,4 [carbazoles, their preparation and pharmaceutical preparations containing them

Country Status (30)

Country Link
US (1) US5721267A (ja)
EP (1) EP0695755B1 (ja)
JP (1) JP2672290B2 (ja)
KR (1) KR100326790B1 (ja)
CN (1) CN1051551C (ja)
AT (1) ATE172463T1 (ja)
AU (1) AU692563B2 (ja)
BR (1) BR9503536A (ja)
CA (1) CA2155148A1 (ja)
CO (1) CO4410329A1 (ja)
CZ (1) CZ288583B6 (ja)
DE (1) DE69505470T2 (ja)
DK (1) DK0695755T3 (ja)
ES (1) ES2123873T3 (ja)
FI (1) FI111258B (ja)
HK (1) HK1012341A1 (ja)
HU (1) HU225567B1 (ja)
IL (1) IL114785A (ja)
MA (1) MA23639A1 (ja)
MY (1) MY117092A (ja)
NO (1) NO304833B1 (ja)
NZ (1) NZ272687A (ja)
PE (1) PE34996A1 (ja)
PL (1) PL180801B1 (ja)
RU (1) RU2162089C2 (ja)
SA (1) SA95160203B1 (ja)
TR (1) TR199500954A1 (ja)
TW (1) TW403652B (ja)
UY (1) UY24010A1 (ja)
ZA (1) ZA956327B (ja)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1283203B1 (it) * 1996-03-07 1998-04-16 Ausimont Spa Composizioni estinguenti la fiamma
US6020298A (en) * 1997-03-05 2000-02-01 Ausimont S.P.A. Solvent cleaning agents including additives of the formula Rf -CFX-L containing perfluoroalkylenic units
DE19744257B4 (de) * 1997-10-07 2004-04-15 Zentaris Gmbh Beta-Carboline und deren Verwendung zur Behandlung von malignen und anderen, auf pathologischen Zellproliferationen beruhenden Erkrankungen
US7122679B2 (en) 2000-05-09 2006-10-17 Cephalon, Inc. Multicyclic compounds and the use thereof
JPWO2003051883A1 (ja) * 2001-12-18 2005-04-28 協和醗酵工業株式会社 インドール誘導体
US7094798B1 (en) 2002-04-26 2006-08-22 Pfizer Inc Inhibitors of checkpoint kinases (Wee1 and Chk1)
AU2003224341A1 (en) * 2002-04-26 2003-11-10 Warner-Lambert Company Llc Inhibitors of checkpoint kinases (wee1 and chk1)
JP2012051804A (ja) * 2008-12-26 2012-03-15 Kyoto Univ Ｅｇ５阻害剤
PT2975024T (pt) * 2009-06-10 2018-05-14 Chugai Pharmaceutical Co Ltd Compostos tetracíclicos
EP3698788A1 (en) 2010-08-20 2020-08-26 Chugai Seiyaku Kabushiki Kaisha Composition comprising tetracyclic compound
HUE040055T2 (hu) 2012-09-25 2019-02-28 Chugai Pharmaceutical Co Ltd RET inhibitor
KR101577098B1 (ko) 2012-11-20 2015-12-14 주식회사 두산 유기 화합물 및 이를 포함하는 유기 전계 발광 소자
WO2015163448A1 (ja) 2014-04-25 2015-10-29 中外製薬株式会社 ４環性化合物を高用量含有する製剤
WO2015163447A1 (ja) 2014-04-25 2015-10-29 中外製薬株式会社 ４環性化合物の新規結晶
TWI765410B (zh) 2014-08-08 2022-05-21 日商中外製藥股份有限公司 ４環性化合物的非晶質體的用途
US11077093B2 (en) 2015-01-16 2021-08-03 Chugai Seiyaku Kabushiki Kaisha Combination drug
TWI825163B (zh) 2018-09-04 2023-12-11 日商中外製藥股份有限公司 四環性化合物的製造方法
KR102509614B1 (ko) * 2022-08-09 2023-03-13 김학수 부직포 패널 제조방법 및 제조장치

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8611762D0 (en) * 1986-05-14 1986-06-25 Wellcome Found Polycyclic biocidal compounds
US4785085A (en) * 1986-11-21 1988-11-15 Bristol-Myers Company Rebeccamycin analogs
NZ227850A (en) * 1988-02-10 1991-11-26 Hoffmann La Roche Indole substituted pyrrole derivatives; preparatory process and medicaments for use against inflammatory immunological, bronchopulmonary or vascular disorders
DE3833008A1 (de) * 1988-09-29 1990-04-05 Goedecke Ag Pyrrolocarbozol-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel
MC2096A1 (fr) * 1989-02-23 1991-02-15 Hoffmann La Roche Pyrroles substitues
US5166204A (en) * 1989-11-01 1992-11-24 Toyama Chemical Co., Ltd. Isoindole derivatives and salts thereof and antitumor agent comprising the same
DE4005969A1 (de) * 1990-02-26 1991-08-29 Boehringer Mannheim Gmbh Neue trisubstituierte pyrrole, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
DE4217964A1 (de) * 1992-05-30 1993-12-02 Goedecke Ag Indolocarbazol-Imide und deren Verwendung
AU678435B2 (en) * 1993-05-10 1997-05-29 F. Hoffmann-La Roche Ag Substituted pyrroles
JP3344586B2 (ja) * 1993-05-28 2002-11-11 セファロン，インコーポレイテッド インドロカルバゾール誘導体を含有する前立腺病理疾患の治療剤

Also Published As

Publication number Publication date
FI111258B (fi) 2003-06-30
MA23639A1 (fr) 1996-04-01
TR199500954A1 (tr) 1996-10-21
DE69505470T2 (de) 1999-05-12
TW403652B (en) 2000-09-01
US5721267A (en) 1998-02-24
ATE172463T1 (de) 1998-11-15
ES2123873T3 (es) 1999-01-16
FI953710A (fi) 1996-02-05
FI953710A0 (fi) 1995-08-03
IL114785A0 (en) 1995-11-27
RU2162089C2 (ru) 2001-01-20
ZA956327B (en) 1996-02-04
BR9503536A (pt) 1996-06-04
DE69505470D1 (de) 1998-11-26
CO4410329A1 (es) 1997-01-09
CN1051551C (zh) 2000-04-19
PL309874A1 (en) 1996-02-05
CN1123280A (zh) 1996-05-29
NO304833B1 (no) 1999-02-22
HU225567B1 (en) 2007-03-28
CA2155148A1 (en) 1996-02-05
HUT73437A (en) 1996-07-29
KR100326790B1 (ko) 2002-07-27
JPH0859666A (ja) 1996-03-05
PE34996A1 (es) 1996-10-01
NZ272687A (en) 1997-04-24
CZ288583B6 (cs) 2001-07-11
HK1012341A1 (en) 1999-07-30
UY24010A1 (es) 2000-12-29
DK0695755T3 (da) 1999-06-28
HU9502270D0 (en) 1995-09-28
MY117092A (en) 2004-05-31
EP0695755A1 (en) 1996-02-07
CZ199795A3 (en) 1996-02-14
NO953052D0 (no) 1995-08-03
EP0695755B1 (en) 1998-10-21
SA95160203B1 (ar) 2005-07-31
KR960007592A (ko) 1996-03-22
AU692563B2 (en) 1998-06-11
JP2672290B2 (ja) 1997-11-05
NO953052L (no) 1996-02-05
AU2722095A (en) 1996-02-15
PL180801B1 (pl) 2001-04-30

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