IL110970A - Mycophenolate Muftil in a non-aqueous crystalline form, pharmaceutical preparations containing it and their preparation - Google Patents
Mycophenolate Muftil in a non-aqueous crystalline form, pharmaceutical preparations containing it and their preparationInfo
- Publication number
- IL110970A IL110970A IL11097094A IL11097094A IL110970A IL 110970 A IL110970 A IL 110970A IL 11097094 A IL11097094 A IL 11097094A IL 11097094 A IL11097094 A IL 11097094A IL 110970 A IL110970 A IL 110970A
- Authority
- IL
- Israel
- Prior art keywords
- compound
- crystalline anhydrous
- salt
- range
- temperature
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12184193A | 1993-09-15 | 1993-09-15 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL110970A0 IL110970A0 (en) | 1994-11-28 |
| IL110970A true IL110970A (en) | 1999-01-26 |
Family
ID=22399119
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL11097094A IL110970A (en) | 1993-09-15 | 1994-09-14 | Mycophenolate Muftil in a non-aqueous crystalline form, pharmaceutical preparations containing it and their preparation |
Country Status (32)
| Country | Link |
|---|---|
| US (2) | US5543408A (fi) |
| EP (1) | EP0724581B1 (fi) |
| JP (1) | JP3411038B2 (fi) |
| KR (1) | KR100349772B1 (fi) |
| CN (1) | CN1060770C (fi) |
| AT (1) | ATE173475T1 (fi) |
| AU (1) | AU677435B2 (fi) |
| BR (1) | BR9407469A (fi) |
| CA (1) | CA2171836C (fi) |
| CZ (1) | CZ292423B6 (fi) |
| DE (1) | DE69414720T2 (fi) |
| DK (1) | DK0724581T3 (fi) |
| ES (1) | ES2123831T3 (fi) |
| FI (1) | FI119639B (fi) |
| HK (1) | HK1012624A1 (fi) |
| HU (1) | HU217300B (fi) |
| IL (1) | IL110970A (fi) |
| LT (1) | LT4052B (fi) |
| LV (1) | LV11326B (fi) |
| MX (1) | MXPA94007099A (fi) |
| NO (1) | NO314727B1 (fi) |
| NZ (1) | NZ273801A (fi) |
| PH (1) | PH30685A (fi) |
| PL (1) | PL178522B1 (fi) |
| RO (2) | RO118075B1 (fi) |
| RU (1) | RU2132849C1 (fi) |
| SG (1) | SG55006A1 (fi) |
| SI (1) | SI9420052B (fi) |
| TW (1) | TW370527B (fi) |
| UA (1) | UA49797C2 (fi) |
| WO (1) | WO1995007902A1 (fi) |
| ZA (1) | ZA947088B (fi) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9512854D0 (en) * | 1995-06-23 | 1995-08-23 | Wellcome Found | Novel formulation |
| IN188985B (fi) | 1998-12-09 | 2002-11-30 | Biocon Ltd | |
| GB0301259D0 (en) | 2003-01-20 | 2003-02-19 | Novartis Ag | Organic compounds |
| GB0307553D0 (en) * | 2003-04-01 | 2003-05-07 | Novartis Ag | Organic compounds |
| US20050187170A1 (en) * | 2003-06-16 | 2005-08-25 | Biocryst Pharmaceuticals, Inc. | Enhancing the efficiency of RNA polymerase inhibitors by using inosine monophosphate dehydrogenase inhibitors |
| EP1667987B1 (en) * | 2003-09-11 | 2008-07-23 | Sandoz AG | Process for the production of mycophenolate mofetil |
| US7683188B2 (en) * | 2004-04-26 | 2010-03-23 | TEVA Gyógyszergyár Zártkōrūen Mūkōdō Részvénytársaság | Process for preparation of mycophenolic acid and ester derivatives thereof |
| CA2555454C (en) * | 2004-04-27 | 2009-12-15 | Sandor Molnar | Mycophenolate mofetil impurity |
| WO2006115509A2 (en) | 2004-06-24 | 2006-11-02 | Novartis Vaccines And Diagnostics Inc. | Small molecule immunopotentiators and assays for their detection |
| CN101014584A (zh) * | 2004-07-20 | 2007-08-08 | 特瓦药厂私人有限公司 | 结晶霉酚酸钠的制备方法 |
| CN100383520C (zh) * | 2004-09-20 | 2008-04-23 | 复旦大学 | 一种测定人血浆中霉酚酸及其代谢物的方法 |
| EP1917010A2 (en) * | 2005-02-08 | 2008-05-07 | Aspreva Pharmaceuticals SA | Compositions and methods for treating vascular, autoimmune and inflammatory diseases |
| US20060235009A1 (en) * | 2005-02-08 | 2006-10-19 | Richard Glickman | Treatment of vascular, autoimmune and inflammatory diseases using low dosages of IMPDH inhibitors |
| US20080280977A1 (en) * | 2005-04-26 | 2008-11-13 | Sandor Molnar | Process for preparation of mycophenolate mofetil and other esters of mycophenolic acid |
| CA2655061A1 (en) | 2006-06-27 | 2008-01-03 | Sandoz Ag | New method for salt preparation |
| CN101953807A (zh) * | 2010-10-09 | 2011-01-26 | 山西普德药业有限公司 | 一种注射用吗替麦考酚酯冻干粉针剂及其制备方法 |
| KR101814474B1 (ko) | 2013-03-14 | 2018-01-12 | 엘커메스 파마 아일랜드 리미티드 | 푸마레이트의 프로드럭 및 다양한 질환을 치료하는데 있어서의 이들의 용도 |
| US8669281B1 (en) | 2013-03-14 | 2014-03-11 | Alkermes Pharma Ireland Limited | Prodrugs of fumarates and their use in treating various diseases |
| US9168246B2 (en) * | 2013-06-27 | 2015-10-27 | Veloxis Pharmaceutical A/S | Regimen for suppressing organ rejection |
| CA2940845C (en) | 2014-02-24 | 2019-09-24 | Alkermes Pharma Ireland Limited | Sulfonamide and sulfinamide prodrugs of fumarates and their use in treating various diseases |
| US11918684B2 (en) | 2017-03-13 | 2024-03-05 | Liqmeds Worldwide Limited | Pharmaceutical composition of oral suspension of immunosuppressive agents |
| AU2022230995A1 (en) | 2021-03-03 | 2023-09-14 | Sana Biotechnology, Inc. | Immunosuppressive therapies for use with cardiomyocyte cell therapies, and associated methods and compositions |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4328213A (en) * | 1979-11-28 | 1982-05-04 | Schering Corporation | Stable injectable labetalol formulation |
| US4478829A (en) * | 1983-04-28 | 1984-10-23 | Armour Pharmaceutical Company | Pharmaceutical preparation containing purified fibronectin |
| US4753935A (en) * | 1987-01-30 | 1988-06-28 | Syntex (U.S.A.) Inc. | Morpholinoethylesters of mycophenolic acid and pharmaceutical compositions |
-
1994
- 1994-09-12 CZ CZ1996788A patent/CZ292423B6/cs not_active IP Right Cessation
- 1994-09-12 EP EP94928054A patent/EP0724581B1/en not_active Expired - Lifetime
- 1994-09-12 DE DE69414720T patent/DE69414720T2/de not_active Expired - Lifetime
- 1994-09-12 HU HU9600652A patent/HU217300B/hu unknown
- 1994-09-12 RU RU96107396A patent/RU2132849C1/ru active
- 1994-09-12 SG SG1996001679A patent/SG55006A1/en unknown
- 1994-09-12 RO RO96-00567A patent/RO118075B1/ro unknown
- 1994-09-12 AU AU77238/94A patent/AU677435B2/en not_active Expired
- 1994-09-12 WO PCT/US1994/010142 patent/WO1995007902A1/en active IP Right Grant
- 1994-09-12 CA CA002171836A patent/CA2171836C/en not_active Expired - Lifetime
- 1994-09-12 BR BR9407469A patent/BR9407469A/pt not_active Application Discontinuation
- 1994-09-12 JP JP50925595A patent/JP3411038B2/ja not_active Expired - Lifetime
- 1994-09-12 NZ NZ273801A patent/NZ273801A/en not_active IP Right Cessation
- 1994-09-12 KR KR1019960701354A patent/KR100349772B1/ko not_active IP Right Cessation
- 1994-09-12 DK DK94928054T patent/DK0724581T3/da active
- 1994-09-12 RO ROA200201154A patent/RO118427B1/ro unknown
- 1994-09-12 CN CN94193413A patent/CN1060770C/zh not_active Expired - Lifetime
- 1994-09-12 ES ES94928054T patent/ES2123831T3/es not_active Expired - Lifetime
- 1994-09-12 AT AT94928054T patent/ATE173475T1/de active
- 1994-09-12 PL PL94313480A patent/PL178522B1/pl unknown
- 1994-09-12 SI SI9420052A patent/SI9420052B/sl unknown
- 1994-09-14 IL IL11097094A patent/IL110970A/en not_active IP Right Cessation
- 1994-09-14 ZA ZA947088A patent/ZA947088B/xx unknown
- 1994-09-14 TW TW083108484A patent/TW370527B/zh not_active IP Right Cessation
- 1994-09-14 PH PH48985A patent/PH30685A/en unknown
- 1994-12-05 US US08/349,236 patent/US5543408A/en not_active Expired - Lifetime
- 1994-12-09 UA UA96031026A patent/UA49797C2/uk unknown
-
1995
- 1995-06-02 US US08/459,991 patent/US5545637A/en not_active Expired - Lifetime
-
1996
- 1996-03-13 FI FI961169A patent/FI119639B/fi not_active IP Right Cessation
- 1996-03-15 LV LVP-96-85A patent/LV11326B/en unknown
- 1996-03-15 LT LT96-028A patent/LT4052B/lt not_active IP Right Cessation
- 1996-03-15 NO NO19961075A patent/NO314727B1/no not_active IP Right Cessation
-
1997
- 1997-12-05 MX MXPA94007099A patent/MXPA94007099A/es active IP Right Grant
-
1998
- 1998-12-17 HK HK98113833A patent/HK1012624A1/xx not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP0724581B1 (en) | Crystalline anhydrous mycophenolate mofetil and intravenous formulation thereof | |
| JP6461945B2 (ja) | ある含有量のマイトマイシンｃを有する凍結乾燥医薬組成物を製造する方法 | |
| EP2210592A2 (en) | Stabilized Freeze-dried Formulation for Cephalosporin Derivatives | |
| JP2016521731A (ja) | 抗がん剤を含む安定な水溶性医薬組成物 | |
| JP4142149B2 (ja) | バンコマイシンの凍結乾燥製剤 | |
| NZ226550A (en) | Vancomycin hydrochloride formulations which may contain gel-inhibiting compounds; processes for making them | |
| WO2018177232A1 (zh) | 难溶性复合物或其溶剂合物、药物组合物及其应用 | |
| WO2012013116A1 (zh) | 含氨基酸稳定剂的替莫唑胺药物组合物及其制备方法 | |
| CA1160571A (en) | Antitumor compositions | |
| JP2001504475A (ja) | キヌプリスチン及びダルホプリスチンに基づく安定化された製薬学的組成物並びにそれらの製造 | |
| JP2001519390A (ja) | 安定剤としてグリシンを含む製薬学的製剤 | |
| US4425348A (en) | Antitumor compositions | |
| US4322424A (en) | Crystalline glucoconate salt of m-AMSA and compositions containing same | |
| US4626541A (en) | Water soluble salt composition of m-AMSA | |
| WO2024009319A1 (en) | Liquid injectable compositions of trilaciclib | |
| CA2503087A1 (en) | Intravenous formulations of pyridoxal 5'-phosphate and method of preparation | |
| TW201302755A (zh) | 含胺基酸穩定劑的替莫唑胺醫藥組成物及其製備方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| EXP | Patent expired |