IL109870A - Process for the preparation of B-lactam crystalline monohydrate - Google Patents
Process for the preparation of B-lactam crystalline monohydrateInfo
- Publication number
- IL109870A IL109870A IL109870A IL10987094A IL109870A IL 109870 A IL109870 A IL 109870A IL 109870 A IL109870 A IL 109870A IL 10987094 A IL10987094 A IL 10987094A IL 109870 A IL109870 A IL 109870A
- Authority
- IL
- Israel
- Prior art keywords
- crystal
- monohydrate
- crystalline
- compound
- dmf
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/071,552 US5352782A (en) | 1993-06-04 | 1993-06-04 | Process for preparing crystalline β-lactam monohydrate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL109870A0 IL109870A0 (en) | 1994-10-07 |
| IL109870A true IL109870A (en) | 1998-06-15 |
Family
ID=22102062
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL109870A IL109870A (en) | 1993-06-04 | 1994-06-02 | Process for the preparation of B-lactam crystalline monohydrate |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US5352782A (fr) |
| EP (1) | EP0627431B1 (fr) |
| JP (1) | JPH06345761A (fr) |
| KR (1) | KR950000702A (fr) |
| CN (1) | CN1045296C (fr) |
| AT (1) | ATE156129T1 (fr) |
| AU (1) | AU682503B2 (fr) |
| BR (1) | BR9402150A (fr) |
| CA (1) | CA2125000A1 (fr) |
| CO (1) | CO4230099A1 (fr) |
| CZ (1) | CZ284225B6 (fr) |
| DE (1) | DE69404560T2 (fr) |
| DK (1) | DK0627431T3 (fr) |
| ES (1) | ES2105524T3 (fr) |
| FI (1) | FI942632A (fr) |
| GR (1) | GR3024989T3 (fr) |
| HU (1) | HU217067B (fr) |
| IL (1) | IL109870A (fr) |
| MY (1) | MY110725A (fr) |
| NO (1) | NO307052B1 (fr) |
| NZ (1) | NZ260652A (fr) |
| PE (1) | PE13295A1 (fr) |
| PH (1) | PH30184A (fr) |
| PL (1) | PL174535B1 (fr) |
| RU (1) | RU2130456C1 (fr) |
| TW (1) | TW449596B (fr) |
| UA (1) | UA34440C2 (fr) |
| YU (1) | YU33494A (fr) |
| ZA (1) | ZA943826B (fr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5399686A (en) * | 1993-06-04 | 1995-03-21 | Eli Lilly And Company | Loracarbef isopropanolate and a process for converting loracarbef isopropanolate to loracarbef monohydrate |
| US5550231A (en) * | 1993-06-15 | 1996-08-27 | Eli Lilly And Company | Loracarbef hydrochloride C1-C3 alcohol solvates and uses thereof |
| US5580977A (en) * | 1995-03-01 | 1996-12-03 | Eli Lilly And Company | Process for preparing loracarbef monohydrate |
| US20060205938A1 (en) * | 2002-11-21 | 2006-09-14 | Yatendra Kumar | Monohydrate solvates of loracarbef |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3502663A (en) * | 1969-04-21 | 1970-03-24 | Lilly Co Eli | Crystalline cephalosporin,method for its manufacture |
| US3531481A (en) * | 1969-04-21 | 1970-09-29 | Lilly Co Eli | Method for manufacture of crystalline cephalosporin |
| ZA887409B (en) * | 1987-10-06 | 1990-06-27 | Lilly Co Eli | Crystalline beta-lactam hydrate |
| CA2002596A1 (fr) * | 1988-11-14 | 1990-05-14 | Thomas M. Eckrich | Hydrates de beta-lactam antibiotiques |
| US4977257A (en) * | 1988-11-14 | 1990-12-11 | Eli Lilly And Company | DMF solvates of a β-lactam antibiotic |
| CA2002597C (fr) * | 1988-11-14 | 1999-03-23 | Thomas M. Eckrich | Solvates de beta-lactam antibiotiques |
| CA2034592C (fr) * | 1990-01-26 | 2001-06-05 | Ralph R. Pfeiffer | Chlorhydrate crystallin d'un nouvel antibiotique de type beta-lactame et procede pour sa fabrication |
-
1993
- 1993-06-04 US US08/071,552 patent/US5352782A/en not_active Expired - Lifetime
-
1994
- 1994-06-01 PL PL94303677A patent/PL174535B1/pl unknown
- 1994-06-01 NZ NZ260652A patent/NZ260652A/en unknown
- 1994-06-01 ZA ZA943826A patent/ZA943826B/xx unknown
- 1994-06-01 DE DE69404560T patent/DE69404560T2/de not_active Expired - Fee Related
- 1994-06-01 BR BR9402150A patent/BR9402150A/pt not_active Application Discontinuation
- 1994-06-01 ES ES94303946T patent/ES2105524T3/es not_active Expired - Lifetime
- 1994-06-01 AT AT94303946T patent/ATE156129T1/de not_active IP Right Cessation
- 1994-06-01 CZ CZ941341A patent/CZ284225B6/cs not_active IP Right Cessation
- 1994-06-01 EP EP94303946A patent/EP0627431B1/fr not_active Expired - Lifetime
- 1994-06-01 DK DK94303946.1T patent/DK0627431T3/da active
- 1994-06-01 TW TW083105007A patent/TW449596B/zh not_active IP Right Cessation
- 1994-06-01 PE PE1994243645A patent/PE13295A1/es not_active Application Discontinuation
- 1994-06-02 PH PH48387A patent/PH30184A/en unknown
- 1994-06-02 MY MYPI94001409A patent/MY110725A/en unknown
- 1994-06-02 UA UA94005240A patent/UA34440C2/uk unknown
- 1994-06-02 NO NO942049A patent/NO307052B1/no not_active IP Right Cessation
- 1994-06-02 CO CO94023736A patent/CO4230099A1/es unknown
- 1994-06-02 IL IL109870A patent/IL109870A/en not_active IP Right Cessation
- 1994-06-02 KR KR1019940012341A patent/KR950000702A/ko active IP Right Grant
- 1994-06-02 CA CA002125000A patent/CA2125000A1/fr not_active Abandoned
- 1994-06-02 AU AU64517/94A patent/AU682503B2/en not_active Ceased
- 1994-06-03 YU YU33494A patent/YU33494A/sh unknown
- 1994-06-03 HU HU9401674A patent/HU217067B/hu not_active IP Right Cessation
- 1994-06-03 RU RU94019423A patent/RU2130456C1/ru active
- 1994-06-03 JP JP6122282A patent/JPH06345761A/ja active Pending
- 1994-06-03 FI FI942632A patent/FI942632A/fi unknown
- 1994-06-03 CN CN94106983A patent/CN1045296C/zh not_active Expired - Fee Related
-
1997
- 1997-10-09 GR GR970402632T patent/GR3024989T3/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |