YU33494A - Postupak za obrazovanje kristalnog beta-laktam monohidrata - Google Patents

Postupak za obrazovanje kristalnog beta-laktam monohidrata

Info

Publication number
YU33494A
YU33494A YU33494A YU33494A YU33494A YU 33494 A YU33494 A YU 33494A YU 33494 A YU33494 A YU 33494A YU 33494 A YU33494 A YU 33494A YU 33494 A YU33494 A YU 33494A
Authority
YU
Yugoslavia
Prior art keywords
lactam
education
monohydrate
procedure
crystal beta
Prior art date
Application number
YU33494A
Other languages
English (en)
Inventor
R.L. Nist
M.E. Wildfeur
Original Assignee
Eli Lilly & Co.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly & Co. filed Critical Eli Lilly & Co.
Publication of YU33494A publication Critical patent/YU33494A/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

Opisan je postupak za obrazovanje kristalnog beta-laktam monihidrata, jedinjenja formule (I) koji obuhvata faze COOH mešanje jedinjenja formule (I), oblika različitog od kristalnog monohidrata, u vodi na temperaturi između oko 30В°C i oko 60В°C; ili izlaganje jedinjenja formule (I), oblika različitog od kristalnog monohidrata, zasićenoj vodenoj pari na temperaturi od oko 90В°C do oko 100В°C; sušenje kristalnog monohidrata; i-filtriranje kristalnog monohidrata.
YU33494A 1993-06-04 1994-06-03 Postupak za obrazovanje kristalnog beta-laktam monohidrata YU33494A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/071,552 US5352782A (en) 1993-06-04 1993-06-04 Process for preparing crystalline β-lactam monohydrate

Publications (1)

Publication Number Publication Date
YU33494A true YU33494A (sh) 1996-10-18

Family

ID=22102062

Family Applications (1)

Application Number Title Priority Date Filing Date
YU33494A YU33494A (sh) 1993-06-04 1994-06-03 Postupak za obrazovanje kristalnog beta-laktam monohidrata

Country Status (29)

Country Link
US (1) US5352782A (sh)
EP (1) EP0627431B1 (sh)
JP (1) JPH06345761A (sh)
KR (1) KR950000702A (sh)
CN (1) CN1045296C (sh)
AT (1) ATE156129T1 (sh)
AU (1) AU682503B2 (sh)
BR (1) BR9402150A (sh)
CA (1) CA2125000A1 (sh)
CO (1) CO4230099A1 (sh)
CZ (1) CZ284225B6 (sh)
DE (1) DE69404560T2 (sh)
DK (1) DK0627431T3 (sh)
ES (1) ES2105524T3 (sh)
FI (1) FI942632A (sh)
GR (1) GR3024989T3 (sh)
HU (1) HU217067B (sh)
IL (1) IL109870A (sh)
MY (1) MY110725A (sh)
NO (1) NO307052B1 (sh)
NZ (1) NZ260652A (sh)
PE (1) PE13295A1 (sh)
PH (1) PH30184A (sh)
PL (1) PL174535B1 (sh)
RU (1) RU2130456C1 (sh)
TW (1) TW449596B (sh)
UA (1) UA34440C2 (sh)
YU (1) YU33494A (sh)
ZA (1) ZA943826B (sh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5399686A (en) * 1993-06-04 1995-03-21 Eli Lilly And Company Loracarbef isopropanolate and a process for converting loracarbef isopropanolate to loracarbef monohydrate
US5550231A (en) * 1993-06-15 1996-08-27 Eli Lilly And Company Loracarbef hydrochloride C1-C3 alcohol solvates and uses thereof
US5580977A (en) * 1995-03-01 1996-12-03 Eli Lilly And Company Process for preparing loracarbef monohydrate
CA2506872A1 (en) * 2002-11-21 2004-06-03 Ranbaxy Laboratories Limited Monohydrate solvates of loracarbef

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3531481A (en) * 1969-04-21 1970-09-29 Lilly Co Eli Method for manufacture of crystalline cephalosporin
US3502663A (en) * 1969-04-21 1970-03-24 Lilly Co Eli Crystalline cephalosporin,method for its manufacture
CA1334970C (en) * 1987-10-06 1995-03-28 Carol Elaine Pasini Crystalline .beta.-lactam hydrate
CA2002597C (en) * 1988-11-14 1999-03-23 Thomas M. Eckrich Solvates of b-lactam antibiotic
CA2002596A1 (en) * 1988-11-14 1990-05-14 Thomas M. Eckrich Hydrates of b-lactam antibiotic
US4977257A (en) * 1988-11-14 1990-12-11 Eli Lilly And Company DMF solvates of a β-lactam antibiotic
CA2034592C (en) * 1990-01-26 2001-06-05 Ralph R. Pfeiffer Crystalline hydrochloride of new beta-lactam antibiotic and process therefor

Also Published As

Publication number Publication date
NZ260652A (en) 1995-09-26
HU217067B (hu) 1999-11-29
JPH06345761A (ja) 1994-12-20
CN1045296C (zh) 1999-09-29
PH30184A (en) 1997-01-21
IL109870A0 (en) 1994-10-07
DE69404560D1 (de) 1997-09-04
ZA943826B (en) 1995-12-01
CA2125000A1 (en) 1994-12-05
NO942049D0 (no) 1994-06-02
AU682503B2 (en) 1997-10-09
CO4230099A1 (es) 1995-10-19
IL109870A (en) 1998-06-15
ATE156129T1 (de) 1997-08-15
ES2105524T3 (es) 1997-10-16
DE69404560T2 (de) 1997-12-18
HUT67975A (en) 1995-05-29
RU94019423A (ru) 1996-04-20
PL303677A1 (en) 1995-01-09
NO942049L (no) 1994-12-05
FI942632A0 (fi) 1994-06-03
CN1097755A (zh) 1995-01-25
RU2130456C1 (ru) 1999-05-20
MY110725A (en) 1999-01-30
PE13295A1 (es) 1995-05-24
CZ134194A3 (en) 1994-12-15
DK0627431T3 (da) 1997-08-25
KR950000702A (ko) 1995-01-03
US5352782A (en) 1994-10-04
GR3024989T3 (en) 1998-01-30
UA34440C2 (uk) 2001-03-15
CZ284225B6 (cs) 1998-09-16
HU9401674D0 (en) 1994-09-28
EP0627431B1 (en) 1997-07-30
TW449596B (en) 2001-08-11
AU6451794A (en) 1994-12-08
FI942632A (fi) 1994-12-05
PL174535B1 (pl) 1998-08-31
NO307052B1 (no) 2000-01-31
BR9402150A (pt) 1994-12-27
EP0627431A1 (en) 1994-12-07

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