ATE156129T1 - Verfahren zur herstellung von kristallisiertem loracarbef monohydrat - Google Patents

Verfahren zur herstellung von kristallisiertem loracarbef monohydrat

Info

Publication number
ATE156129T1
ATE156129T1 AT94303946T AT94303946T ATE156129T1 AT E156129 T1 ATE156129 T1 AT E156129T1 AT 94303946 T AT94303946 T AT 94303946T AT 94303946 T AT94303946 T AT 94303946T AT E156129 T1 ATE156129 T1 AT E156129T1
Authority
AT
Austria
Prior art keywords
producing crystallized
loracarbef monohydrate
loracarbef
monohydrate
crystallized
Prior art date
Application number
AT94303946T
Other languages
English (en)
Inventor
Robert Louis Nist
Marvin Emanuel Wildfeuer
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE156129T1 publication Critical patent/ATE156129T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/085Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
AT94303946T 1993-06-04 1994-06-01 Verfahren zur herstellung von kristallisiertem loracarbef monohydrat ATE156129T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/071,552 US5352782A (en) 1993-06-04 1993-06-04 Process for preparing crystalline β-lactam monohydrate

Publications (1)

Publication Number Publication Date
ATE156129T1 true ATE156129T1 (de) 1997-08-15

Family

ID=22102062

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94303946T ATE156129T1 (de) 1993-06-04 1994-06-01 Verfahren zur herstellung von kristallisiertem loracarbef monohydrat

Country Status (29)

Country Link
US (1) US5352782A (de)
EP (1) EP0627431B1 (de)
JP (1) JPH06345761A (de)
KR (1) KR950000702A (de)
CN (1) CN1045296C (de)
AT (1) ATE156129T1 (de)
AU (1) AU682503B2 (de)
BR (1) BR9402150A (de)
CA (1) CA2125000A1 (de)
CO (1) CO4230099A1 (de)
CZ (1) CZ284225B6 (de)
DE (1) DE69404560T2 (de)
DK (1) DK0627431T3 (de)
ES (1) ES2105524T3 (de)
FI (1) FI942632A (de)
GR (1) GR3024989T3 (de)
HU (1) HU217067B (de)
IL (1) IL109870A (de)
MY (1) MY110725A (de)
NO (1) NO307052B1 (de)
NZ (1) NZ260652A (de)
PE (1) PE13295A1 (de)
PH (1) PH30184A (de)
PL (1) PL174535B1 (de)
RU (1) RU2130456C1 (de)
TW (1) TW449596B (de)
UA (1) UA34440C2 (de)
YU (1) YU33494A (de)
ZA (1) ZA943826B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5399686A (en) * 1993-06-04 1995-03-21 Eli Lilly And Company Loracarbef isopropanolate and a process for converting loracarbef isopropanolate to loracarbef monohydrate
US5550231A (en) * 1993-06-15 1996-08-27 Eli Lilly And Company Loracarbef hydrochloride C1-C3 alcohol solvates and uses thereof
US5580977A (en) * 1995-03-01 1996-12-03 Eli Lilly And Company Process for preparing loracarbef monohydrate
AU2003283624A1 (en) * 2002-11-21 2004-06-15 Ranbaxy Laboratories Limited Monohydrate solvates of loracarbef

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3531481A (en) * 1969-04-21 1970-09-29 Lilly Co Eli Method for manufacture of crystalline cephalosporin
US3502663A (en) * 1969-04-21 1970-03-24 Lilly Co Eli Crystalline cephalosporin,method for its manufacture
CA1334970C (en) * 1987-10-06 1995-03-28 Carol Elaine Pasini Crystalline .beta.-lactam hydrate
US4977257A (en) * 1988-11-14 1990-12-11 Eli Lilly And Company DMF solvates of a β-lactam antibiotic
CA2002596A1 (en) * 1988-11-14 1990-05-14 Thomas M. Eckrich Hydrates of b-lactam antibiotic
CA2002597C (en) * 1988-11-14 1999-03-23 Thomas M. Eckrich Solvates of b-lactam antibiotic
CA2034592C (en) * 1990-01-26 2001-06-05 Ralph R. Pfeiffer Crystalline hydrochloride of new beta-lactam antibiotic and process therefor

Also Published As

Publication number Publication date
IL109870A (en) 1998-06-15
EP0627431B1 (de) 1997-07-30
CO4230099A1 (es) 1995-10-19
FI942632A (fi) 1994-12-05
AU6451794A (en) 1994-12-08
DE69404560D1 (de) 1997-09-04
FI942632A0 (fi) 1994-06-03
NO942049D0 (no) 1994-06-02
HUT67975A (en) 1995-05-29
DK0627431T3 (da) 1997-08-25
MY110725A (en) 1999-01-30
KR950000702A (ko) 1995-01-03
ZA943826B (en) 1995-12-01
JPH06345761A (ja) 1994-12-20
CN1097755A (zh) 1995-01-25
AU682503B2 (en) 1997-10-09
DE69404560T2 (de) 1997-12-18
NO942049L (no) 1994-12-05
CA2125000A1 (en) 1994-12-05
EP0627431A1 (de) 1994-12-07
RU94019423A (ru) 1996-04-20
PL174535B1 (pl) 1998-08-31
HU217067B (hu) 1999-11-29
PL303677A1 (en) 1995-01-09
CZ284225B6 (cs) 1998-09-16
CN1045296C (zh) 1999-09-29
NO307052B1 (no) 2000-01-31
HU9401674D0 (en) 1994-09-28
TW449596B (en) 2001-08-11
UA34440C2 (uk) 2001-03-15
PE13295A1 (es) 1995-05-24
ES2105524T3 (es) 1997-10-16
IL109870A0 (en) 1994-10-07
US5352782A (en) 1994-10-04
YU33494A (sh) 1996-10-18
BR9402150A (pt) 1994-12-27
PH30184A (en) 1997-01-21
GR3024989T3 (en) 1998-01-30
NZ260652A (en) 1995-09-26
RU2130456C1 (ru) 1999-05-20
CZ134194A3 (en) 1994-12-15

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee