DK0627431T3 - Fremgangsmåde til fremstilling af krystallinsk loracarbef-monohydrat - Google Patents

Fremgangsmåde til fremstilling af krystallinsk loracarbef-monohydrat

Info

Publication number
DK0627431T3
DK0627431T3 DK94303946.1T DK94303946T DK0627431T3 DK 0627431 T3 DK0627431 T3 DK 0627431T3 DK 94303946 T DK94303946 T DK 94303946T DK 0627431 T3 DK0627431 T3 DK 0627431T3
Authority
DK
Denmark
Prior art keywords
preparation
loracarbef monohydrate
crystalline
crystalline loracarbef
monohydrate
Prior art date
Application number
DK94303946.1T
Other languages
Danish (da)
English (en)
Inventor
Robert Louis Nist
Marvin Emanuel Wildfeuer
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of DK0627431T3 publication Critical patent/DK0627431T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/085Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
DK94303946.1T 1993-06-04 1994-06-01 Fremgangsmåde til fremstilling af krystallinsk loracarbef-monohydrat DK0627431T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/071,552 US5352782A (en) 1993-06-04 1993-06-04 Process for preparing crystalline β-lactam monohydrate

Publications (1)

Publication Number Publication Date
DK0627431T3 true DK0627431T3 (da) 1997-08-25

Family

ID=22102062

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94303946.1T DK0627431T3 (da) 1993-06-04 1994-06-01 Fremgangsmåde til fremstilling af krystallinsk loracarbef-monohydrat

Country Status (29)

Country Link
US (1) US5352782A (de)
EP (1) EP0627431B1 (de)
JP (1) JPH06345761A (de)
KR (1) KR950000702A (de)
CN (1) CN1045296C (de)
AT (1) ATE156129T1 (de)
AU (1) AU682503B2 (de)
BR (1) BR9402150A (de)
CA (1) CA2125000A1 (de)
CO (1) CO4230099A1 (de)
CZ (1) CZ284225B6 (de)
DE (1) DE69404560T2 (de)
DK (1) DK0627431T3 (de)
ES (1) ES2105524T3 (de)
FI (1) FI942632A (de)
GR (1) GR3024989T3 (de)
HU (1) HU217067B (de)
IL (1) IL109870A (de)
MY (1) MY110725A (de)
NO (1) NO307052B1 (de)
NZ (1) NZ260652A (de)
PE (1) PE13295A1 (de)
PH (1) PH30184A (de)
PL (1) PL174535B1 (de)
RU (1) RU2130456C1 (de)
TW (1) TW449596B (de)
UA (1) UA34440C2 (de)
YU (1) YU33494A (de)
ZA (1) ZA943826B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5399686A (en) * 1993-06-04 1995-03-21 Eli Lilly And Company Loracarbef isopropanolate and a process for converting loracarbef isopropanolate to loracarbef monohydrate
US5550231A (en) * 1993-06-15 1996-08-27 Eli Lilly And Company Loracarbef hydrochloride C1-C3 alcohol solvates and uses thereof
US5580977A (en) * 1995-03-01 1996-12-03 Eli Lilly And Company Process for preparing loracarbef monohydrate
AU2003283624A1 (en) * 2002-11-21 2004-06-15 Ranbaxy Laboratories Limited Monohydrate solvates of loracarbef

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3531481A (en) * 1969-04-21 1970-09-29 Lilly Co Eli Method for manufacture of crystalline cephalosporin
US3502663A (en) * 1969-04-21 1970-03-24 Lilly Co Eli Crystalline cephalosporin,method for its manufacture
YU46699B (sh) * 1987-10-06 1994-04-05 Eli Lilly And Co. Kristalni monohidratni oblik 1-karbacefalosporina
US4977257A (en) * 1988-11-14 1990-12-11 Eli Lilly And Company DMF solvates of a β-lactam antibiotic
CA2002596A1 (en) * 1988-11-14 1990-05-14 Thomas M. Eckrich Hydrates of b-lactam antibiotic
CA2002597C (en) * 1988-11-14 1999-03-23 Thomas M. Eckrich Solvates of b-lactam antibiotic
CA2034592C (en) * 1990-01-26 2001-06-05 Ralph R. Pfeiffer Crystalline hydrochloride of new beta-lactam antibiotic and process therefor

Also Published As

Publication number Publication date
PH30184A (en) 1997-01-21
CA2125000A1 (en) 1994-12-05
CN1097755A (zh) 1995-01-25
CZ284225B6 (cs) 1998-09-16
US5352782A (en) 1994-10-04
PL174535B1 (pl) 1998-08-31
YU33494A (sh) 1996-10-18
JPH06345761A (ja) 1994-12-20
HU217067B (hu) 1999-11-29
IL109870A0 (en) 1994-10-07
PE13295A1 (es) 1995-05-24
MY110725A (en) 1999-01-30
GR3024989T3 (en) 1998-01-30
KR950000702A (ko) 1995-01-03
NZ260652A (en) 1995-09-26
PL303677A1 (en) 1995-01-09
DE69404560T2 (de) 1997-12-18
AU682503B2 (en) 1997-10-09
HU9401674D0 (en) 1994-09-28
FI942632A (fi) 1994-12-05
NO942049L (no) 1994-12-05
TW449596B (en) 2001-08-11
BR9402150A (pt) 1994-12-27
CZ134194A3 (en) 1994-12-15
ATE156129T1 (de) 1997-08-15
NO307052B1 (no) 2000-01-31
RU2130456C1 (ru) 1999-05-20
CO4230099A1 (es) 1995-10-19
ES2105524T3 (es) 1997-10-16
DE69404560D1 (de) 1997-09-04
CN1045296C (zh) 1999-09-29
UA34440C2 (uk) 2001-03-15
NO942049D0 (no) 1994-06-02
AU6451794A (en) 1994-12-08
ZA943826B (en) 1995-12-01
EP0627431A1 (de) 1994-12-07
HUT67975A (en) 1995-05-29
IL109870A (en) 1998-06-15
EP0627431B1 (de) 1997-07-30
RU94019423A (ru) 1996-04-20
FI942632A0 (fi) 1994-06-03

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