IL107626A - Aqueous drug composition having property of reversible thermosetting gelation - Google Patents
Aqueous drug composition having property of reversible thermosetting gelationInfo
- Publication number
- IL107626A IL107626A IL107626A IL10762693A IL107626A IL 107626 A IL107626 A IL 107626A IL 107626 A IL107626 A IL 107626A IL 10762693 A IL10762693 A IL 10762693A IL 107626 A IL107626 A IL 107626A
- Authority
- IL
- Israel
- Prior art keywords
- property
- drug composition
- aqueous drug
- reversible thermosetting
- application
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Materials For Medical Uses (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11234593 | 1993-04-16 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL107626A0 IL107626A0 (en) | 1994-02-27 |
IL107626A true IL107626A (en) | 1997-09-30 |
Family
ID=14584369
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL107626A IL107626A (en) | 1993-04-16 | 1993-11-16 | Aqueous drug composition having property of reversible thermosetting gelation |
Country Status (17)
Country | Link |
---|---|
US (1) | US5624962A (ru) |
EP (1) | EP0694310B1 (ru) |
KR (1) | KR0162025B1 (ru) |
CN (1) | CN1048393C (ru) |
AT (1) | ATE189772T1 (ru) |
AU (1) | AU668447B2 (ru) |
CA (1) | CA2153234C (ru) |
DE (1) | DE69327878T2 (ru) |
DK (1) | DK0694310T3 (ru) |
ES (1) | ES2141775T3 (ru) |
FI (1) | FI112778B (ru) |
HK (1) | HK1017805A1 (ru) |
HU (1) | HU220864B1 (ru) |
IL (1) | IL107626A (ru) |
NO (1) | NO311635B1 (ru) |
RU (1) | RU2108112C1 (ru) |
WO (1) | WO1994023750A1 (ru) |
Families Citing this family (77)
Publication number | Priority date | Publication date | Assignee | Title |
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US6436425B1 (en) | 1988-11-16 | 2002-08-20 | Mdv Technologies, Inc. | Method and non-gelling composition for inhibiting post-surgical adhesions |
US5346703A (en) | 1990-08-07 | 1994-09-13 | Mediventures, Inc. | Body cavity drug delivery with thermo-irreversible polyoxyalkylene and ionic polysaccharide gels |
US5318780A (en) * | 1991-10-30 | 1994-06-07 | Mediventures Inc. | Medical uses of in situ formed gels |
ZA952521B (en) * | 1994-03-28 | 1996-03-15 | Univ Columbia | Composition for inactivating irritants in fluids |
EP0782850A4 (en) * | 1994-10-13 | 1998-03-04 | Wakamoto Pharma Co Ltd | LYOPHILIZED PREPARATION FOR PRODUCING A REVERSIBLE THERMOGELING MEDICINAL WATER-BASED |
DE19511322C2 (de) | 1995-03-28 | 1999-09-02 | Mann Gerhard Chem Pharm Fab | Sterile Augengele mit einem Gehalt an mittelkettigen Triglyceriden und Verfahren zu deren Herstellung |
US5843470A (en) | 1995-10-06 | 1998-12-01 | Mdv Technologies, Inc. | Method and composition for inhibiting post-surgical adhesions |
CA2232855C (en) * | 1997-04-10 | 2007-10-09 | Roche Consumer Health (Worldwide) Sa | Pharmaceutical formulation |
WO1998051281A1 (fr) * | 1997-05-14 | 1998-11-19 | Senju Pharmaceutical Co., Ltd. | Preparations a base de suspensions aqueuses possedant d'excellentes proprietes de redispersion |
EP1039932A1 (en) * | 1997-12-23 | 2000-10-04 | Alliance Pharmaceutical Corporation | Methods and compositions for the delivery of pharmaceutical agents and/or the prevention of adhesions |
US6197347B1 (en) | 1998-06-29 | 2001-03-06 | Andrx Pharmaceuticals, Inc. | Oral dosage for the controlled release of analgesic |
ES2155027B1 (es) * | 1999-05-24 | 2001-12-01 | Univ Pais Vasco | Geles para propositos multiples, reversibles y degradables. |
ES2273702T3 (es) * | 1999-06-11 | 2007-05-16 | Cytyc Corporation | Composicion liquido en gel para cartografiar un conducto galactoforo mamario antes de la escxision quirurgica del conducto o de otro tejido mamario. |
US6576224B1 (en) * | 1999-07-06 | 2003-06-10 | Sinuspharma, Inc. | Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis |
US20020061281A1 (en) * | 1999-07-06 | 2002-05-23 | Osbakken Robert S. | Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis |
JP2001158750A (ja) * | 1999-12-02 | 2001-06-12 | Lion Corp | 眼科用組成物及び抗アレルギー薬の持続性向上方法 |
JP3450805B2 (ja) * | 2000-08-08 | 2003-09-29 | わかもと製薬株式会社 | 水性医薬組成物 |
US7420030B2 (en) | 2000-09-08 | 2008-09-02 | The Board Of Regents Of The University Of Texas System | Aminopeptidase A (APA) targeting peptides for the treatment of cancer |
AU2001291159A1 (en) * | 2000-09-20 | 2002-04-02 | Shahinian Jr., Lee | Self-preserved nasal, inhalable, and topical ophthalmic preparations and medications |
JP4820024B2 (ja) * | 2001-01-10 | 2011-11-24 | 昭和薬品化工株式会社 | 局所麻酔用組成物 |
CA2454357A1 (en) * | 2001-07-18 | 2003-01-30 | Wadih Arap | An anti-angiogenic state in mice and humans with retinal photoreceptor cell degeneration |
US20040048243A1 (en) * | 2001-09-07 | 2004-03-11 | Wadih Arap | Methods and compositions for in vitro targeting |
US6846846B2 (en) * | 2001-10-23 | 2005-01-25 | The Trustees Of Columbia University In The City Of New York | Gentle-acting skin disinfectants |
US7745425B2 (en) * | 2002-02-07 | 2010-06-29 | The Trustees Of Columbia University In The City Of New York | Non-irritating compositions containing zinc salts |
US7879365B2 (en) * | 2002-02-07 | 2011-02-01 | The Trustees Of Columbia University In The City Of New York | Zinc salt compositions for the prevention of dermal and mucosal irritation |
CA2475224C (en) * | 2002-02-07 | 2011-11-01 | The Trustees Of Columbia University In The City Of New York | Zinc salt compositions for the prevention of mucosal irritation from spermicides and microbicides |
KR20100102749A (ko) * | 2002-02-22 | 2010-09-24 | 산텐 세이야꾸 가부시키가이샤 | 미립자 결막하 투여를 위한 약물 수송 시스템 |
US20030211173A1 (en) * | 2002-05-08 | 2003-11-13 | Veach Tom C. | Lubrication composition |
AU2003264498A1 (en) * | 2002-09-18 | 2004-04-08 | Wakamoto Pharmaceutical Co., Ltd. | Transparent and reversibly heat-gelling aqueous compositions |
US7220431B2 (en) | 2002-11-27 | 2007-05-22 | Regents Of The University Of Minnesota | Methods and compositions for applying pharmacologic agents to the ear |
JP2004196787A (ja) * | 2002-12-04 | 2004-07-15 | Santen Pharmaceut Co Ltd | 結膜下デポによるドラッグデリバリーシステム |
KR20050086903A (ko) * | 2002-12-10 | 2005-08-30 | 쇼와 야쿠힝 가코 가부시키가이샤 | 국소마취용 조성물 |
US20050085446A1 (en) * | 2003-04-14 | 2005-04-21 | Babu M.K. M. | Fluoroquinolone formulations and methods of making and using the same |
JP4669960B2 (ja) * | 2003-06-03 | 2011-04-13 | 株式会社 メドレックス | 局所麻酔薬を含有する口中用または咽頭部用製剤 |
CA2532730C (en) * | 2003-07-17 | 2013-02-26 | The Trustees Of Columbia University In The City Of New York | Antimicrobial compositions containing synergistic combinations of quaternary ammonium compounds and essential oils and/or constituents thereof |
TWI347847B (en) * | 2003-08-20 | 2011-09-01 | Santen Pharmaceutical Co Ltd | Drug delivery system for sub-tenon administration of fine particles |
FR2860718B1 (fr) * | 2003-10-09 | 2006-02-24 | Jean Pascal Conduzorgues | Nouvelle formulation et ses applications dans le domaines cosmetiques ou pharmaceutiques |
US20070110689A1 (en) * | 2004-01-15 | 2007-05-17 | Mark Feldschuh | Oral anaesthetic gel |
US7658947B2 (en) | 2004-06-25 | 2010-02-09 | Kimberly-Clark Worldwide, Inc. | Thermo-gelling composition |
JP2007277095A (ja) * | 2004-07-02 | 2007-10-25 | Wakamoto Pharmaceut Co Ltd | アジスロマイシン含有可逆性熱ゲル化水性組成物 |
US7459416B2 (en) * | 2004-07-12 | 2008-12-02 | Panasonic Corporation | Fluid bearing unit and spindle motor using the same |
EP1858482B1 (en) | 2005-03-10 | 2014-04-23 | 3M Innovative Properties Company | Methods of reducing microbial contamination |
JP4979258B2 (ja) * | 2005-04-08 | 2012-07-18 | ロート製薬株式会社 | アシタザノラスト含有水性組成物 |
CN100463668C (zh) * | 2005-05-09 | 2009-02-25 | 凌沛学 | 可逆性热凝胶化水性药物组合物 |
CN100430069C (zh) * | 2005-07-28 | 2008-11-05 | 凌沛学 | 一种中药及其复方的可逆性热凝胶化水性药物组合物 |
DE602006012865D1 (de) * | 2005-10-17 | 2010-04-22 | Kowa Co | Indometacin enthaltende flüssige zubereitung zur externen anwendung |
EA008737B1 (ru) * | 2005-12-07 | 2007-08-31 | Леонид Андреевич Кожемякин | Средство для профилактики и лечения конъюнктивитов и кератитов различной этиологии (варианты), способ его применения |
US7759327B2 (en) | 2006-01-06 | 2010-07-20 | The Trustees Of Columbia University In The City Of New York | Compositions containing zinc salts for coating medical articles |
US20070249546A1 (en) * | 2006-04-22 | 2007-10-25 | Sawaya Assad S | Ophthalmic and related aqueous solutions containing antifungal agents, uses therefor and methods for preparing them |
US20070254854A1 (en) * | 2006-05-01 | 2007-11-01 | Medi-Flex, Inc. | Aqueous Antiseptic Solution and Compatible Anionic Dye for Staining Skin |
US20080108674A1 (en) * | 2006-05-01 | 2008-05-08 | Enturia, Inc. | Cationic antiseptic and dye formulation |
US20070253909A1 (en) * | 2006-05-01 | 2007-11-01 | Medi-Flex, Inc. | Aqueous Antiseptic Solution and Compatible Cationic Dye for Staining Skin |
TW200808375A (en) * | 2006-05-12 | 2008-02-16 | Otsuka Pharma Co Ltd | Hydrogel suspension and manufacturing process thereof |
EA014780B1 (ru) * | 2007-01-05 | 2011-02-28 | Промед Экспортс Пвт. Лтд. | Офтальмическая композиция |
DE102007002073A1 (de) * | 2007-01-09 | 2008-07-10 | Matthias Habenicht | Mittel zur Pflege und antimikrobiellen Behandlung der Haut |
JP5340149B2 (ja) * | 2007-06-26 | 2013-11-13 | わかもと製薬株式会社 | 水性組成物 |
WO2009028674A1 (ja) * | 2007-08-29 | 2009-03-05 | Wakamoto Pharmaceutical Co., Ltd. | ラタノプロスト含有水性医薬組成物 |
WO2009074853A2 (en) * | 2007-12-10 | 2009-06-18 | Promed Research Centre | Ophthalmic composition comprising phenylephrine |
CA2723458C (en) * | 2008-05-14 | 2014-01-28 | Otonomy, Inc. | Controlled release corticosteroid compositions and methods for the treatment of otic disorders |
US10517839B2 (en) * | 2008-06-09 | 2019-12-31 | Cornell University | Mast cell inhibition in diseases of the retina and vitreous |
TW201023912A (en) * | 2008-12-05 | 2010-07-01 | Alcon Res Ltd | Pharmaceutical suspension |
CN105362221A (zh) * | 2009-03-03 | 2016-03-02 | 爱尔康研究有限公司 | 向眼部递送受体酪氨酸激酶抑制性(RTKi)化合物的药物组合物 |
US8912236B2 (en) * | 2009-03-03 | 2014-12-16 | Alcon Research, Ltd. | Pharmaceutical composition for delivery of receptor tyrosine kinase inhibiting (RTKi) compounds to the eye |
MX2011008731A (es) * | 2009-03-03 | 2011-09-29 | Alcon Res Ltd | Composicion farmaceutica para el suministro de compuestos inhibidores de la tirosina cinasa receptora (rtki) para los ojos. |
US8299079B2 (en) | 2009-05-22 | 2012-10-30 | Kaufman Herbert E | Preparations and methods for ameliorating or reducing presbyopia |
US20100298335A1 (en) * | 2009-05-22 | 2010-11-25 | Kaufman Herbert E | Preparations and Methods for Ameliorating or Reducing Presbyopia |
US20130149394A1 (en) | 2010-08-27 | 2013-06-13 | Wakamoto Pharmaceutical Co., Ltd. | Aqueous ophthalmic composition |
TWI544922B (zh) | 2011-05-19 | 2016-08-11 | 愛爾康研究有限公司 | 高濃度歐羅派特錠(olopatadine)眼用組成物 |
WO2013169458A1 (en) * | 2012-05-11 | 2013-11-14 | Bausch & Lomb Incorporated | Pharmaceutical compositions and methods for treating, controlling, ameliorating, or reversing conditions of dry eye |
RU2485939C1 (ru) * | 2012-06-19 | 2013-06-27 | Станислав Анатольевич Кедик | Офтальмологический препарат в виде глазных капель, содержащий дисульфирам и таурин |
US10507245B2 (en) * | 2012-07-19 | 2019-12-17 | Luis Felipe Vejarano Restrepo | Ophthalmic formulation and method for ameliorating presbyopia |
RU2517033C1 (ru) * | 2013-03-05 | 2014-05-27 | федеральное государственное бюджетное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова" Министерства здравоохранения Российской Федерации | Композиция для комплексного лечения больных с первичной открытоугольной глаукомой и заболеваниями глазной поверхности |
CN103239390B (zh) * | 2013-05-15 | 2014-08-06 | 中国人民解放军第三军医大学第二附属医院 | 托吡卡胺眼用温度敏感原位凝胶及其制备方法 |
EP3082868A1 (en) * | 2013-12-20 | 2016-10-26 | The Procter & Gamble Company | Stable liquid medication containing diphenhydramine |
JP6714247B2 (ja) * | 2017-10-06 | 2020-06-24 | 有限会社ジーエヌコーポレーション | 尿道狭窄治療剤および尿道狭窄治療方法 |
WO2019230750A1 (ja) * | 2018-05-29 | 2019-12-05 | 学校法人 神野学園 | 外用組成物 |
WO2020112655A1 (en) * | 2018-11-26 | 2020-06-04 | Aiviva Biopharma, Inc. | Pharmaceutical biodissolvable gels for drug delivery |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3311577A (en) * | 1965-03-29 | 1967-03-28 | Burton Parsons Chemicals Inc | Underwater contact lens solution |
US4100271A (en) * | 1976-02-26 | 1978-07-11 | Cooper Laboratories, Inc. | Clear, water-miscible, liquid pharmaceutical vehicles and compositions which gel at body temperature for drug delivery to mucous membranes |
US4188373A (en) * | 1976-02-26 | 1980-02-12 | Cooper Laboratories, Inc. | Clear, water-miscible, liquid pharmaceutical vehicles and compositions which gel at body temperature for drug delivery to mucous membranes |
DE2714065A1 (de) * | 1977-03-30 | 1978-10-12 | Boehringer Mannheim Gmbh | Instillationszubereitung |
US4478822A (en) * | 1983-05-16 | 1984-10-23 | Merck & Co., Inc. | Drug delivery system utilizing thermosetting gels |
US4474752A (en) * | 1983-05-16 | 1984-10-02 | Merck & Co., Inc. | Drug delivery system utilizing thermosetting gels |
US4474753A (en) * | 1983-05-16 | 1984-10-02 | Merck & Co., Inc. | Topical drug delivery system utilizing thermosetting gels |
US4474751A (en) * | 1983-05-16 | 1984-10-02 | Merck & Co., Inc. | Ophthalmic drug delivery system utilizing thermosetting gels |
FR2588189B1 (fr) * | 1985-10-03 | 1988-12-02 | Merck Sharp & Dohme | Composition pharmaceutique de type a transition de phase liquide-gel |
GB2203039B (en) * | 1987-03-02 | 1990-10-24 | American Cyanamid Co | Stable ophthalmic preparations containing acetazolamide |
US5252318A (en) * | 1990-06-15 | 1993-10-12 | Allergan, Inc. | Reversible gelation compositions and methods of use |
US5077033A (en) * | 1990-08-07 | 1991-12-31 | Mediventures Inc. | Ophthalmic drug delivery with thermo-irreversible gels of polxoxyalkylene polymer and ionic polysaccharide |
MX9200339A (es) * | 1991-01-28 | 1992-08-01 | Hoechst Ag | Preparado para la liberacion controlada de sustancias activas, que son apropiadas como terapeuticos o para mejorar el crecimiento y el aprovechamiento de los piensos en rumiantes |
AU679937B2 (en) * | 1992-11-18 | 1997-07-17 | Johnson & Johnson Consumer Products, Inc. | Extrudable compositions for topical or transdermal drug delivery |
-
1993
- 1993-11-10 US US08/397,064 patent/US5624962A/en not_active Expired - Lifetime
- 1993-11-10 KR KR1019950703156A patent/KR0162025B1/ko not_active IP Right Cessation
- 1993-11-10 EP EP93924801A patent/EP0694310B1/en not_active Expired - Lifetime
- 1993-11-10 CA CA002153234A patent/CA2153234C/en not_active Expired - Fee Related
- 1993-11-10 AU AU54333/94A patent/AU668447B2/en not_active Expired
- 1993-11-10 ES ES93924801T patent/ES2141775T3/es not_active Expired - Lifetime
- 1993-11-10 AT AT93924801T patent/ATE189772T1/de not_active IP Right Cessation
- 1993-11-10 HU HU9502086A patent/HU220864B1/hu not_active IP Right Cessation
- 1993-11-10 RU RU95122560A patent/RU2108112C1/ru not_active IP Right Cessation
- 1993-11-10 WO PCT/JP1993/001636 patent/WO1994023750A1/ja active IP Right Grant
- 1993-11-10 DE DE69327878T patent/DE69327878T2/de not_active Expired - Lifetime
- 1993-11-10 DK DK93924801T patent/DK0694310T3/da active
- 1993-11-15 CN CN93121431A patent/CN1048393C/zh not_active Expired - Lifetime
- 1993-11-16 IL IL107626A patent/IL107626A/xx not_active IP Right Cessation
-
1995
- 1995-07-26 FI FI953575A patent/FI112778B/fi not_active IP Right Cessation
- 1995-08-14 NO NO19953189A patent/NO311635B1/no not_active IP Right Cessation
-
1998
- 1998-12-08 HK HK98112925A patent/HK1017805A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
FI953575A0 (fi) | 1995-07-26 |
KR960700075A (ko) | 1996-01-19 |
NO953189D0 (no) | 1995-08-14 |
HU220864B1 (en) | 2002-06-29 |
FI953575A (fi) | 1995-07-26 |
DK0694310T3 (da) | 2000-06-05 |
HK1017805A1 (en) | 1999-11-26 |
CN1097593A (zh) | 1995-01-25 |
CA2153234A1 (en) | 1994-10-27 |
AU668447B2 (en) | 1996-05-02 |
CA2153234C (en) | 1999-02-16 |
RU2108112C1 (ru) | 1998-04-10 |
NO953189L (no) | 1995-08-14 |
IL107626A0 (en) | 1994-02-27 |
DE69327878D1 (de) | 2000-03-23 |
AU5433394A (en) | 1994-11-08 |
HUT71676A (en) | 1996-01-29 |
ES2141775T3 (es) | 2000-04-01 |
US5624962A (en) | 1997-04-29 |
EP0694310A4 (en) | 1996-04-24 |
CN1048393C (zh) | 2000-01-19 |
EP0694310A1 (en) | 1996-01-31 |
HU9502086D0 (en) | 1995-09-28 |
WO1994023750A1 (en) | 1994-10-27 |
ATE189772T1 (de) | 2000-03-15 |
DE69327878T2 (de) | 2000-06-15 |
EP0694310B1 (en) | 2000-02-16 |
NO311635B1 (no) | 2001-12-27 |
KR0162025B1 (ko) | 1998-12-01 |
FI112778B (fi) | 2004-01-15 |
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