IL103224A - Stabilized pharmaceutical compositions containing derivatives of vitamins d2 and d3 - Google Patents

Stabilized pharmaceutical compositions containing derivatives of vitamins d2 and d3

Info

Publication number
IL103224A
IL103224A IL10322492A IL10322492A IL103224A IL 103224 A IL103224 A IL 103224A IL 10322492 A IL10322492 A IL 10322492A IL 10322492 A IL10322492 A IL 10322492A IL 103224 A IL103224 A IL 103224A
Authority
IL
Israel
Prior art keywords
pharmaceutical composition
ingredient
composition according
ingredients
vitamin
Prior art date
Application number
IL10322492A
Other languages
English (en)
Other versions
IL103224A0 (en
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to IL10322492A priority Critical patent/IL103224A/en
Application filed by Teva Pharma filed Critical Teva Pharma
Publication of IL103224A0 publication Critical patent/IL103224A0/xx
Priority to DK93306978.3T priority patent/DK0588539T3/da
Priority to DE69307977T priority patent/DE69307977T2/de
Priority to AT93306978T priority patent/ATE148630T1/de
Priority to EP93306978A priority patent/EP0588539B1/en
Priority to ES93306978T priority patent/ES2098672T3/es
Priority to US08/120,210 priority patent/US5565442A/en
Priority to ZA936835A priority patent/ZA936835B/xx
Priority to AU47408/93A priority patent/AU667742B2/en
Priority to CA002106423A priority patent/CA2106423C/en
Priority to JP23389093A priority patent/JP3464691B2/ja
Priority to US08/657,676 priority patent/US5804573A/en
Priority to GR970400788T priority patent/GR3023127T3/el
Publication of IL103224A publication Critical patent/IL103224A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/592—9,10-Secoergostane derivatives, e.g. ergocalciferol, i.e. vitamin D2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL10322492A 1992-09-18 1992-09-18 Stabilized pharmaceutical compositions containing derivatives of vitamins d2 and d3 IL103224A (en)

Priority Applications (13)

Application Number Priority Date Filing Date Title
IL10322492A IL103224A (en) 1992-09-18 1992-09-18 Stabilized pharmaceutical compositions containing derivatives of vitamins d2 and d3
DK93306978.3T DK0588539T3 (da) 1992-09-18 1993-09-03 Stabiliserede farmaceutiske præparater indeholdende derivater af vitamin D2 og D3
DE69307977T DE69307977T2 (de) 1992-09-18 1993-09-03 Stabilisierte Derivate von Vitamin D2 und D3 enthaltende pharmazeutische Zusammensetzungen
AT93306978T ATE148630T1 (de) 1992-09-18 1993-09-03 Stabilisierte derivate von vitamin d2 und d3 enthaltende pharmazeutische zusammensetzungen
EP93306978A EP0588539B1 (en) 1992-09-18 1993-09-03 Stabilized pharmaceutical compositions containing derivatives of vitamins D2 and D3
ES93306978T ES2098672T3 (es) 1992-09-18 1993-09-03 Composiciones farmaceuticas estabilizadas que contienen derivados de vitaminas d2 y d3.
US08/120,210 US5565442A (en) 1992-09-18 1993-09-13 Stabilized pharmaceutical compositions containing derivatives of vitamins D2 and D3
ZA936835A ZA936835B (en) 1992-09-18 1993-09-16 Stabilized pharmaceutical compositions containing derivatives of vitamins D2 and D3
AU47408/93A AU667742B2 (en) 1992-09-18 1993-09-16 Stabilized pharmaceutical compositions containing derivatives of vitamins D2 and D3
CA002106423A CA2106423C (en) 1992-09-18 1993-09-17 Stabilized pharmaceutical compositions containing derivatives of vitamins d2 and d3
JP23389093A JP3464691B2 (ja) 1992-09-18 1993-09-20 固型製薬組成物
US08/657,676 US5804573A (en) 1992-09-18 1996-05-31 Stabilized pharmaceutical composition containing derivative of vitamins D2 and D3
GR970400788T GR3023127T3 (en) 1992-09-18 1997-04-14 Stabilized pharmaceutical compositions containing derivatives of vitamins D2 and D3

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL10322492A IL103224A (en) 1992-09-18 1992-09-18 Stabilized pharmaceutical compositions containing derivatives of vitamins d2 and d3

Publications (2)

Publication Number Publication Date
IL103224A0 IL103224A0 (en) 1993-02-21
IL103224A true IL103224A (en) 1998-08-16

Family

ID=11064050

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10322492A IL103224A (en) 1992-09-18 1992-09-18 Stabilized pharmaceutical compositions containing derivatives of vitamins d2 and d3

Country Status (12)

Country Link
US (2) US5565442A (el)
EP (1) EP0588539B1 (el)
JP (1) JP3464691B2 (el)
AT (1) ATE148630T1 (el)
AU (1) AU667742B2 (el)
CA (1) CA2106423C (el)
DE (1) DE69307977T2 (el)
DK (1) DK0588539T3 (el)
ES (1) ES2098672T3 (el)
GR (1) GR3023127T3 (el)
IL (1) IL103224A (el)
ZA (1) ZA936835B (el)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9325445D0 (en) 1993-12-13 1994-02-16 Cortecs Ltd Pharmaceutical formulations
JP2656448B2 (ja) * 1994-07-25 1997-09-24 マイクロアルジェコーポレーション株式会社 カルシウムを主成分とする健康食品
DE19710054A1 (de) * 1997-03-12 1998-09-17 Merck Patent Gmbh Pharmazeutische Zubereitung
ITFI970184A1 (it) * 1997-07-30 1999-01-30 Menarini Farma Ind Composizioni farmaceutiche contenenti vitamina d e calcio,loro preparazione ed uso terapeutico
IL153378A0 (en) * 2000-07-18 2003-07-06 Bone Care Internat Inc STABILIZED 1alpha-HYDROXY VITAMIN D
US6475526B1 (en) 2001-06-05 2002-11-05 Jeffrey B. Smith Zinc containing compositions for anti-viral use
US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
MXPA04009979A (es) * 2002-04-09 2004-12-13 Flamel Tech Sa Formulacion farmaceutica oral bajo forma de suspension acuosa de microcapsulas que permiten la liberacion modificada de amoxicilina.
CA2480826C (fr) 2002-04-09 2012-02-07 Flamel Technologies Formulation pharmaceutique orale sous forme de suspension aqueuse de microcapsules permettant la liberation modifiee de principe(s) actif(s)
US7148211B2 (en) * 2002-09-18 2006-12-12 Genzyme Corporation Formulation for lipophilic agents
US20040058895A1 (en) * 2002-09-18 2004-03-25 Bone Care International, Inc. Multi-use vessels for vitamin D formulations
US20040053895A1 (en) * 2002-09-18 2004-03-18 Bone Care International, Inc. Multi-use vessels for vitamin D formulations
US6855341B2 (en) * 2002-11-04 2005-02-15 Jeffrey B. Smith Anti-viral compositions and methods of making and using the anti-viral compositions
US20080274209A1 (en) * 2002-11-04 2008-11-06 Integritas Pharma, Inc. Methods of treating inflammation
US20060189586A1 (en) * 2003-06-11 2006-08-24 Cleland Jeffrey L Pharmaceutical compositions comprising active vitamin D compounds
US20050232981A1 (en) 2004-04-15 2005-10-20 Ben-Sasson Shmuel A Compositions capable of facilitating penetration across a biological barrier
US7700365B2 (en) 2004-10-29 2010-04-20 Mayo Foundation For Medical Education And Research Vitamin D deficiencies
FR2889810A1 (fr) * 2005-05-24 2007-02-23 Flamel Technologies Sa Forme medicamenteuse orale, microparticulaire, anti-mesurage
WO2009111873A1 (en) * 2008-03-12 2009-09-17 Cytochroma, Inc. Stabilized 1,25-dihydroxyvitamin d2 and method of making same
US20110212534A1 (en) * 2008-08-11 2011-09-01 Taylor Robert L Methods for determining levels of 1,25 dihydroxy vitamin d2 and d3
BRPI0918652B1 (pt) 2008-09-17 2021-10-19 Chiasma, Inc. Composição farmacêutica compreendendo um meio hidrofóbico e uma forma sólida que compreende polipeptídeo e sal de ácido graxo de cadeia média, processo de produção da mesma e forma de dosagem oral
MX339746B (es) 2009-01-27 2016-06-08 Berg Llc Vitamina d3 y análogos de la misma para aliviar efectos secundarios asociados con la quimioterapia.
JP5978130B2 (ja) 2009-08-14 2016-08-24 バーグ エルエルシー 脱毛症を治療するためのビタミンｄ３およびその類似体
EP2468265A3 (en) * 2010-12-04 2013-01-02 DEEF Pharmaceutical Industries Co. Homogeneous preparations containing vitamin D
KR20160002836A (ko) 2013-03-27 2016-01-08 피에스엠 헬스케어 유한회사 안정화된 비타민 d 제형
WO2014194133A1 (en) 2013-05-29 2014-12-04 Berg Llc Preventing or mitigating chemotherapy induced alopecia using vitamin d
US11071743B1 (en) * 2015-01-16 2021-07-27 Gregory M. Fahy Effective, non-toxic treatments for brain cancer
US10238709B2 (en) 2015-02-03 2019-03-26 Chiasma, Inc. Method of treating diseases
US11141457B1 (en) 2020-12-28 2021-10-12 Amryt Endo, Inc. Oral octreotide therapy and contraceptive methods

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932634A (en) * 1973-06-28 1976-01-13 Pfizer Inc. High potency vitamin water dispersible formulations
JPS58206533A (ja) * 1982-05-27 1983-12-01 Teijin Ltd 活性型ビタミンｄ↓３誘導体組成物及びそれを活性成分とする薬剤
JPS59155309A (ja) * 1983-02-22 1984-09-04 Teijin Ltd 活性型ビタミンｄ↓３類組成物
CA1272953A (en) * 1984-10-08 1990-08-21 Yuji Makino Pharmaceutical composition for external use containing active-type vitamin d.sub.3
CA1317546C (en) * 1985-07-01 1993-05-11 Werner Meier Pharmaceutical preparations containing mixtures of hydroxy derivatives of vitamin d
JPS62149619A (ja) * 1985-09-05 1987-07-03 Teijin Ltd 活性型ビタミンｄ３類注射用組成物
DD266099A1 (de) * 1987-09-28 1989-03-22 Jenapharm Veb Verfahren zur herstellung von stabilen waessrigen vitamin-d-loesungen
JPH0331257Y2 (el) * 1987-10-31 1991-07-02
JP2525478B2 (ja) * 1989-03-01 1996-08-21 帝人株式会社 安定性の改良された活性型ビタミンｄ▲下３▼類固型製剤
JPH02240024A (ja) * 1989-03-13 1990-09-25 Ss Pharmaceut Co Ltd 活性型ビタミンｄ↓３類製剤用組成物
DK0398217T3 (da) * 1989-05-18 1994-02-14 Hoffmann La Roche Dehydrocholecalciferolderivater
DK0437225T3 (da) * 1990-01-10 1994-06-27 Hoffmann La Roche Topiske præparater
JP2963718B2 (ja) * 1990-03-06 1999-10-18 グレラン製薬株式会社 ビタミンｄ▲下３▼類含有製剤
JP2787364B2 (ja) * 1990-03-29 1998-08-13 大塚製薬株式会社 脂溶性ビタミン注射液
JP2845342B2 (ja) * 1990-04-28 1999-01-13 大正製薬株式会社 ビタミンｄ▲下３▼誘導体含有固形製剤組成物
JP2974734B2 (ja) * 1990-07-12 1999-11-10 中外製薬株式会社 安定な活性型ビタミンｄ▲下３▼類製剤
JPH04198129A (ja) * 1990-11-28 1992-07-17 Sumitomo Pharmaceut Co Ltd 活性型ビタミンｄ↓３類含有組成物

Also Published As

Publication number Publication date
GR3023127T3 (en) 1997-07-30
DE69307977D1 (de) 1997-03-20
CA2106423A1 (en) 1994-03-19
ATE148630T1 (de) 1997-02-15
DK0588539T3 (da) 1997-03-10
JP3464691B2 (ja) 2003-11-10
JPH06219952A (ja) 1994-08-09
EP0588539B1 (en) 1997-02-05
CA2106423C (en) 2005-02-22
US5804573A (en) 1998-09-08
EP0588539A1 (en) 1994-03-23
AU4740893A (en) 1994-03-24
AU667742B2 (en) 1996-04-04
US5565442A (en) 1996-10-15
ES2098672T3 (es) 1997-05-01
DE69307977T2 (de) 1997-08-28
ZA936835B (en) 1994-04-14
IL103224A0 (en) 1993-02-21

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