ZA936835B - Stabilized pharmaceutical compositions containing derivatives of vitamins D2 and D3 - Google Patents

Stabilized pharmaceutical compositions containing derivatives of vitamins D2 and D3

Info

Publication number
ZA936835B
ZA936835B ZA936835A ZA936835A ZA936835B ZA 936835 B ZA936835 B ZA 936835B ZA 936835 A ZA936835 A ZA 936835A ZA 936835 A ZA936835 A ZA 936835A ZA 936835 B ZA936835 B ZA 936835B
Authority
ZA
South Africa
Prior art keywords
vitamins
pharmaceutical compositions
compositions containing
containing derivatives
stabilized pharmaceutical
Prior art date
Application number
ZA936835A
Other languages
English (en)
Inventor
David Isaac Silver
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharma filed Critical Teva Pharma
Publication of ZA936835B publication Critical patent/ZA936835B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/592—9,10-Secoergostane derivatives, e.g. ergocalciferol, i.e. vitamin D2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA936835A 1992-09-18 1993-09-16 Stabilized pharmaceutical compositions containing derivatives of vitamins D2 and D3 ZA936835B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL10322492A IL103224A (en) 1992-09-18 1992-09-18 Stabilized pharmaceutical compositions containing derivatives of vitamins d2 and d3

Publications (1)

Publication Number Publication Date
ZA936835B true ZA936835B (en) 1994-04-14

Family

ID=11064050

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA936835A ZA936835B (en) 1992-09-18 1993-09-16 Stabilized pharmaceutical compositions containing derivatives of vitamins D2 and D3

Country Status (12)

Country Link
US (2) US5565442A (xx)
EP (1) EP0588539B1 (xx)
JP (1) JP3464691B2 (xx)
AT (1) ATE148630T1 (xx)
AU (1) AU667742B2 (xx)
CA (1) CA2106423C (xx)
DE (1) DE69307977T2 (xx)
DK (1) DK0588539T3 (xx)
ES (1) ES2098672T3 (xx)
GR (1) GR3023127T3 (xx)
IL (1) IL103224A (xx)
ZA (1) ZA936835B (xx)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9325445D0 (en) 1993-12-13 1994-02-16 Cortecs Ltd Pharmaceutical formulations
JP2656448B2 (ja) * 1994-07-25 1997-09-24 マイクロアルジェコーポレーション株式会社 カルシウムを主成分とする健康食品
DE19710054A1 (de) * 1997-03-12 1998-09-17 Merck Patent Gmbh Pharmazeutische Zubereitung
ITFI970184A1 (it) * 1997-07-30 1999-01-30 Menarini Farma Ind Composizioni farmaceutiche contenenti vitamina d e calcio,loro preparazione ed uso terapeutico
IL153378A0 (en) * 2000-07-18 2003-07-06 Bone Care Internat Inc STABILIZED 1alpha-HYDROXY VITAMIN D
US6475526B1 (en) 2001-06-05 2002-11-05 Jeffrey B. Smith Zinc containing compositions for anti-viral use
US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
MXPA04009979A (es) * 2002-04-09 2004-12-13 Flamel Tech Sa Formulacion farmaceutica oral bajo forma de suspension acuosa de microcapsulas que permiten la liberacion modificada de amoxicilina.
CA2480826C (fr) 2002-04-09 2012-02-07 Flamel Technologies Formulation pharmaceutique orale sous forme de suspension aqueuse de microcapsules permettant la liberation modifiee de principe(s) actif(s)
US7148211B2 (en) * 2002-09-18 2006-12-12 Genzyme Corporation Formulation for lipophilic agents
US20040058895A1 (en) * 2002-09-18 2004-03-25 Bone Care International, Inc. Multi-use vessels for vitamin D formulations
US20040053895A1 (en) * 2002-09-18 2004-03-18 Bone Care International, Inc. Multi-use vessels for vitamin D formulations
US6855341B2 (en) * 2002-11-04 2005-02-15 Jeffrey B. Smith Anti-viral compositions and methods of making and using the anti-viral compositions
US20080274209A1 (en) * 2002-11-04 2008-11-06 Integritas Pharma, Inc. Methods of treating inflammation
US20060189586A1 (en) * 2003-06-11 2006-08-24 Cleland Jeffrey L Pharmaceutical compositions comprising active vitamin D compounds
US20050232981A1 (en) 2004-04-15 2005-10-20 Ben-Sasson Shmuel A Compositions capable of facilitating penetration across a biological barrier
US7700365B2 (en) 2004-10-29 2010-04-20 Mayo Foundation For Medical Education And Research Vitamin D deficiencies
FR2889810A1 (fr) * 2005-05-24 2007-02-23 Flamel Technologies Sa Forme medicamenteuse orale, microparticulaire, anti-mesurage
WO2009111873A1 (en) * 2008-03-12 2009-09-17 Cytochroma, Inc. Stabilized 1,25-dihydroxyvitamin d2 and method of making same
US20110212534A1 (en) * 2008-08-11 2011-09-01 Taylor Robert L Methods for determining levels of 1,25 dihydroxy vitamin d2 and d3
BRPI0918652B1 (pt) 2008-09-17 2021-10-19 Chiasma, Inc. Composição farmacêutica compreendendo um meio hidrofóbico e uma forma sólida que compreende polipeptídeo e sal de ácido graxo de cadeia média, processo de produção da mesma e forma de dosagem oral
MX339746B (es) 2009-01-27 2016-06-08 Berg Llc Vitamina d3 y análogos de la misma para aliviar efectos secundarios asociados con la quimioterapia.
JP5978130B2 (ja) 2009-08-14 2016-08-24 バーグ エルエルシー 脱毛症を治療するためのビタミンｄ３およびその類似体
EP2468265A3 (en) * 2010-12-04 2013-01-02 DEEF Pharmaceutical Industries Co. Homogeneous preparations containing vitamin D
KR20160002836A (ko) 2013-03-27 2016-01-08 피에스엠 헬스케어 유한회사 안정화된 비타민 d 제형
WO2014194133A1 (en) 2013-05-29 2014-12-04 Berg Llc Preventing or mitigating chemotherapy induced alopecia using vitamin d
US11071743B1 (en) * 2015-01-16 2021-07-27 Gregory M. Fahy Effective, non-toxic treatments for brain cancer
US10238709B2 (en) 2015-02-03 2019-03-26 Chiasma, Inc. Method of treating diseases
US11141457B1 (en) 2020-12-28 2021-10-12 Amryt Endo, Inc. Oral octreotide therapy and contraceptive methods

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932634A (en) * 1973-06-28 1976-01-13 Pfizer Inc. High potency vitamin water dispersible formulations
JPS58206533A (ja) * 1982-05-27 1983-12-01 Teijin Ltd 活性型ビタミンｄ↓３誘導体組成物及びそれを活性成分とする薬剤
JPS59155309A (ja) * 1983-02-22 1984-09-04 Teijin Ltd 活性型ビタミンｄ↓３類組成物
CA1272953A (en) * 1984-10-08 1990-08-21 Yuji Makino Pharmaceutical composition for external use containing active-type vitamin d.sub.3
CA1317546C (en) * 1985-07-01 1993-05-11 Werner Meier Pharmaceutical preparations containing mixtures of hydroxy derivatives of vitamin d
JPS62149619A (ja) * 1985-09-05 1987-07-03 Teijin Ltd 活性型ビタミンｄ３類注射用組成物
DD266099A1 (de) * 1987-09-28 1989-03-22 Jenapharm Veb Verfahren zur herstellung von stabilen waessrigen vitamin-d-loesungen
JPH0331257Y2 (xx) * 1987-10-31 1991-07-02
JP2525478B2 (ja) * 1989-03-01 1996-08-21 帝人株式会社 安定性の改良された活性型ビタミンｄ▲下３▼類固型製剤
JPH02240024A (ja) * 1989-03-13 1990-09-25 Ss Pharmaceut Co Ltd 活性型ビタミンｄ↓３類製剤用組成物
DK0398217T3 (da) * 1989-05-18 1994-02-14 Hoffmann La Roche Dehydrocholecalciferolderivater
DK0437225T3 (da) * 1990-01-10 1994-06-27 Hoffmann La Roche Topiske præparater
JP2963718B2 (ja) * 1990-03-06 1999-10-18 グレラン製薬株式会社 ビタミンｄ▲下３▼類含有製剤
JP2787364B2 (ja) * 1990-03-29 1998-08-13 大塚製薬株式会社 脂溶性ビタミン注射液
JP2845342B2 (ja) * 1990-04-28 1999-01-13 大正製薬株式会社 ビタミンｄ▲下３▼誘導体含有固形製剤組成物
JP2974734B2 (ja) * 1990-07-12 1999-11-10 中外製薬株式会社 安定な活性型ビタミンｄ▲下３▼類製剤
JPH04198129A (ja) * 1990-11-28 1992-07-17 Sumitomo Pharmaceut Co Ltd 活性型ビタミンｄ↓３類含有組成物

Also Published As

Publication number Publication date
GR3023127T3 (en) 1997-07-30
IL103224A (en) 1998-08-16
DE69307977D1 (de) 1997-03-20
CA2106423A1 (en) 1994-03-19
ATE148630T1 (de) 1997-02-15
DK0588539T3 (da) 1997-03-10
JP3464691B2 (ja) 2003-11-10
JPH06219952A (ja) 1994-08-09
EP0588539B1 (en) 1997-02-05
CA2106423C (en) 2005-02-22
US5804573A (en) 1998-09-08
EP0588539A1 (en) 1994-03-23
AU4740893A (en) 1994-03-24
AU667742B2 (en) 1996-04-04
US5565442A (en) 1996-10-15
ES2098672T3 (es) 1997-05-01
DE69307977T2 (de) 1997-08-28
IL103224A0 (en) 1993-02-21

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