IL103224A - Stabilized pharmaceutical compositions containing derivatives of vitamins d2 and d3 - Google Patents

Stabilized pharmaceutical compositions containing derivatives of vitamins d2 and d3

Info

Publication number
IL103224A
IL103224A IL10322492A IL10322492A IL103224A IL 103224 A IL103224 A IL 103224A IL 10322492 A IL10322492 A IL 10322492A IL 10322492 A IL10322492 A IL 10322492A IL 103224 A IL103224 A IL 103224A
Authority
IL
Israel
Prior art keywords
pharmaceutical composition
ingredient
composition according
ingredients
vitamin
Prior art date
Application number
IL10322492A
Other languages
English (en)
Other versions
IL103224A0 (en
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to IL10322492A priority Critical patent/IL103224A/en
Application filed by Teva Pharma filed Critical Teva Pharma
Publication of IL103224A0 publication Critical patent/IL103224A0/xx
Priority to DK93306978.3T priority patent/DK0588539T3/da
Priority to DE69307977T priority patent/DE69307977T2/de
Priority to ES93306978T priority patent/ES2098672T3/es
Priority to AT93306978T priority patent/ATE148630T1/de
Priority to EP93306978A priority patent/EP0588539B1/de
Priority to US08/120,210 priority patent/US5565442A/en
Priority to ZA936835A priority patent/ZA936835B/xx
Priority to AU47408/93A priority patent/AU667742B2/en
Priority to CA002106423A priority patent/CA2106423C/en
Priority to JP23389093A priority patent/JP3464691B2/ja
Priority to US08/657,676 priority patent/US5804573A/en
Priority to GR970400788T priority patent/GR3023127T3/el
Publication of IL103224A publication Critical patent/IL103224A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/592—9,10-Secoergostane derivatives, e.g. ergocalciferol, i.e. vitamin D2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Obesity (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Nutrition Science (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL10322492A 1992-09-18 1992-09-18 Stabilized pharmaceutical compositions containing derivatives of vitamins d2 and d3 IL103224A (en)

Priority Applications (13)

Application Number Priority Date Filing Date Title
IL10322492A IL103224A (en) 1992-09-18 1992-09-18 Stabilized pharmaceutical compositions containing derivatives of vitamins d2 and d3
DK93306978.3T DK0588539T3 (da) 1992-09-18 1993-09-03 Stabiliserede farmaceutiske præparater indeholdende derivater af vitamin D2 og D3
DE69307977T DE69307977T2 (de) 1992-09-18 1993-09-03 Stabilisierte Derivate von Vitamin D2 und D3 enthaltende pharmazeutische Zusammensetzungen
ES93306978T ES2098672T3 (es) 1992-09-18 1993-09-03 Composiciones farmaceuticas estabilizadas que contienen derivados de vitaminas d2 y d3.
AT93306978T ATE148630T1 (de) 1992-09-18 1993-09-03 Stabilisierte derivate von vitamin d2 und d3 enthaltende pharmazeutische zusammensetzungen
EP93306978A EP0588539B1 (de) 1992-09-18 1993-09-03 Stabilisierte Derivate von Vitamin D2 und D3 enthaltende pharmazeutische Zusammensetzungen
US08/120,210 US5565442A (en) 1992-09-18 1993-09-13 Stabilized pharmaceutical compositions containing derivatives of vitamins D2 and D3
ZA936835A ZA936835B (en) 1992-09-18 1993-09-16 Stabilized pharmaceutical compositions containing derivatives of vitamins D2 and D3
AU47408/93A AU667742B2 (en) 1992-09-18 1993-09-16 Stabilized pharmaceutical compositions containing derivatives of vitamins D2 and D3
CA002106423A CA2106423C (en) 1992-09-18 1993-09-17 Stabilized pharmaceutical compositions containing derivatives of vitamins d2 and d3
JP23389093A JP3464691B2 (ja) 1992-09-18 1993-09-20 固型製薬組成物
US08/657,676 US5804573A (en) 1992-09-18 1996-05-31 Stabilized pharmaceutical composition containing derivative of vitamins D2 and D3
GR970400788T GR3023127T3 (en) 1992-09-18 1997-04-14 Stabilized pharmaceutical compositions containing derivatives of vitamins D2 and D3

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL10322492A IL103224A (en) 1992-09-18 1992-09-18 Stabilized pharmaceutical compositions containing derivatives of vitamins d2 and d3

Publications (2)

Publication Number Publication Date
IL103224A0 IL103224A0 (en) 1993-02-21
IL103224A true IL103224A (en) 1998-08-16

Family

ID=11064050

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10322492A IL103224A (en) 1992-09-18 1992-09-18 Stabilized pharmaceutical compositions containing derivatives of vitamins d2 and d3

Country Status (12)

Country Link
US (2) US5565442A (de)
EP (1) EP0588539B1 (de)
JP (1) JP3464691B2 (de)
AT (1) ATE148630T1 (de)
AU (1) AU667742B2 (de)
CA (1) CA2106423C (de)
DE (1) DE69307977T2 (de)
DK (1) DK0588539T3 (de)
ES (1) ES2098672T3 (de)
GR (1) GR3023127T3 (de)
IL (1) IL103224A (de)
ZA (1) ZA936835B (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9325445D0 (en) 1993-12-13 1994-02-16 Cortecs Ltd Pharmaceutical formulations
JP2656448B2 (ja) * 1994-07-25 1997-09-24 マイクロアルジェコーポレーション株式会社 カルシウムを主成分とする健康食品
DE19710054A1 (de) * 1997-03-12 1998-09-17 Merck Patent Gmbh Pharmazeutische Zubereitung
ITFI970184A1 (it) * 1997-07-30 1999-01-30 Menarini Farma Ind Composizioni farmaceutiche contenenti vitamina d e calcio,loro preparazione ed uso terapeutico
JP2004504295A (ja) * 2000-07-18 2004-02-12 ボーン　ケア　インターナショナル　インコーポレイテッド 安定化１α−ヒドロキシビタミンＤ
US6475526B1 (en) 2001-06-05 2002-11-05 Jeffrey B. Smith Zinc containing compositions for anti-viral use
US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
PT1492511E (pt) 2002-04-09 2009-04-09 Flamel Tech Sa Formulação farmacêutica oral na forma de suspensão aquosa de microcápsulas para libertação modificada de princípio(s) activo(s)
CA2480824A1 (fr) * 2002-04-09 2003-10-16 Flamel Technologies Formulation pharmaceutique orale sous forme de suspension aqueuse de microcapsules permettant la liberation modifiee d'amoxicilline
US20040058895A1 (en) * 2002-09-18 2004-03-25 Bone Care International, Inc. Multi-use vessels for vitamin D formulations
US7148211B2 (en) * 2002-09-18 2006-12-12 Genzyme Corporation Formulation for lipophilic agents
US20040053895A1 (en) * 2002-09-18 2004-03-18 Bone Care International, Inc. Multi-use vessels for vitamin D formulations
US20080274209A1 (en) * 2002-11-04 2008-11-06 Integritas Pharma, Inc. Methods of treating inflammation
US6855341B2 (en) * 2002-11-04 2005-02-15 Jeffrey B. Smith Anti-viral compositions and methods of making and using the anti-viral compositions
US20060189586A1 (en) * 2003-06-11 2006-08-24 Cleland Jeffrey L Pharmaceutical compositions comprising active vitamin D compounds
AU2005329255B2 (en) 2004-04-15 2010-09-30 Chiasma, Inc. Compositions capable of facilitating penetration across a biological barrier
US7700365B2 (en) 2004-10-29 2010-04-20 Mayo Foundation For Medical Education And Research Vitamin D deficiencies
FR2889810A1 (fr) * 2005-05-24 2007-02-23 Flamel Technologies Sa Forme medicamenteuse orale, microparticulaire, anti-mesurage
JP5492099B2 (ja) * 2008-03-12 2014-05-14 シトクロマ インコーポレイテッド 安定化１，２５−ジヒドロキシビタミンｄ２及びその製造方法
WO2010019566A2 (en) * 2008-08-11 2010-02-18 Mayo Foundation For Medical Education And Research Methods for determining levels of 1,25 dihydroxy vitamin d2 and d3
MX2011002836A (es) 2008-09-17 2011-04-28 Chiasma Inc Composiciones farmaceúticas y métodos de administración relacionados.
CN107019795A (zh) 2009-01-27 2017-08-08 博格有限责任公司 用于减轻与化疗有关的副作用的维生素d3化合物
MX366076B (es) 2009-08-14 2019-06-27 Berg Llc Vitamina d3 y analogos de la misma para tratar alopecia.
EP2468265A3 (de) * 2010-12-04 2013-01-02 DEEF Pharmaceutical Industries Co. Homogene Zubereitungen mit Vitamin D
US9801821B2 (en) 2013-03-27 2017-10-31 Psm Healthcare Limited Stabilized vitamin D formulations
NZ714801A (en) 2013-05-29 2021-07-30 Berg Llc Preventing or mitigating chemotherapy induced alopecia using vitamin d
US11071743B1 (en) * 2015-01-16 2021-07-27 Gregory M. Fahy Effective, non-toxic treatments for brain cancer
MA41462A (fr) 2015-02-03 2021-05-12 Chiasma Inc Méthode de traitement de maladies
US11141457B1 (en) 2020-12-28 2021-10-12 Amryt Endo, Inc. Oral octreotide therapy and contraceptive methods

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932634A (en) * 1973-06-28 1976-01-13 Pfizer Inc. High potency vitamin water dispersible formulations
JPS58206533A (ja) * 1982-05-27 1983-12-01 Teijin Ltd 活性型ビタミンｄ↓３誘導体組成物及びそれを活性成分とする薬剤
JPS59155309A (ja) * 1983-02-22 1984-09-04 Teijin Ltd 活性型ビタミンｄ↓３類組成物
CA1272953A (en) * 1984-10-08 1990-08-21 Yuji Makino Pharmaceutical composition for external use containing active-type vitamin d.sub.3
CA1317546C (en) * 1985-07-01 1993-05-11 Werner Meier Pharmaceutical preparations containing mixtures of hydroxy derivatives of vitamin d
JPS62149619A (ja) * 1985-09-05 1987-07-03 Teijin Ltd 活性型ビタミンｄ３類注射用組成物
DD266099A1 (de) * 1987-09-28 1989-03-22 Jenapharm Veb Verfahren zur herstellung von stabilen waessrigen vitamin-d-loesungen
JPH0331257Y2 (de) * 1987-10-31 1991-07-02
JP2525478B2 (ja) * 1989-03-01 1996-08-21 帝人株式会社 安定性の改良された活性型ビタミンｄ▲下３▼類固型製剤
JPH02240024A (ja) * 1989-03-13 1990-09-25 Ss Pharmaceut Co Ltd 活性型ビタミンｄ↓３類製剤用組成物
EP0398217B1 (de) * 1989-05-18 1994-01-12 F. Hoffmann-La Roche Ag Dehydrocholecalciferolderivate
DE59101404D1 (de) * 1990-01-10 1994-05-26 Hoffmann La Roche Topische Präparate.
JP2963718B2 (ja) * 1990-03-06 1999-10-18 グレラン製薬株式会社 ビタミンｄ▲下３▼類含有製剤
JP2787364B2 (ja) * 1990-03-29 1998-08-13 大塚製薬株式会社 脂溶性ビタミン注射液
JP2845342B2 (ja) * 1990-04-28 1999-01-13 大正製薬株式会社 ビタミンｄ▲下３▼誘導体含有固形製剤組成物
JP2974734B2 (ja) * 1990-07-12 1999-11-10 中外製薬株式会社 安定な活性型ビタミンｄ▲下３▼類製剤
JPH04198129A (ja) * 1990-11-28 1992-07-17 Sumitomo Pharmaceut Co Ltd 活性型ビタミンｄ↓３類含有組成物

Also Published As

Publication number Publication date
EP0588539A1 (de) 1994-03-23
AU667742B2 (en) 1996-04-04
IL103224A0 (en) 1993-02-21
US5565442A (en) 1996-10-15
ES2098672T3 (es) 1997-05-01
DK0588539T3 (da) 1997-03-10
GR3023127T3 (en) 1997-07-30
ZA936835B (en) 1994-04-14
US5804573A (en) 1998-09-08
JPH06219952A (ja) 1994-08-09
AU4740893A (en) 1994-03-24
CA2106423C (en) 2005-02-22
DE69307977D1 (de) 1997-03-20
CA2106423A1 (en) 1994-03-19
DE69307977T2 (de) 1997-08-28
JP3464691B2 (ja) 2003-11-10
ATE148630T1 (de) 1997-02-15
EP0588539B1 (de) 1997-02-05

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