IL102946A0 - Pyrazole derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same - Google Patents

Pyrazole derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same

Info

Publication number
IL102946A0
IL102946A0 IL102946A IL10294692A IL102946A0 IL 102946 A0 IL102946 A0 IL 102946A0 IL 102946 A IL102946 A IL 102946A IL 10294692 A IL10294692 A IL 10294692A IL 102946 A0 IL102946 A0 IL 102946A0
Authority
IL
Israel
Prior art keywords
processes
preparation
same
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL102946A
Other languages
English (en)
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB919119267A external-priority patent/GB9119267D0/en
Priority claimed from GB929204464A external-priority patent/GB9204464D0/en
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of IL102946A0 publication Critical patent/IL102946A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL102946A 1991-09-09 1992-08-25 Pyrazole derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same IL102946A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919119267A GB9119267D0 (en) 1991-09-09 1991-09-09 Pyrazole derivatives
GB929204464A GB9204464D0 (en) 1992-03-02 1992-03-02 New heterocyclic derivatives

Publications (1)

Publication Number Publication Date
IL102946A0 true IL102946A0 (en) 1993-01-31

Family

ID=26299519

Family Applications (1)

Application Number Title Priority Date Filing Date
IL102946A IL102946A0 (en) 1991-09-09 1992-08-25 Pyrazole derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same

Country Status (10)

Country Link
US (3) US5356897A (de)
EP (1) EP0531901A3 (de)
JP (2) JPH0788386B2 (de)
CN (1) CN1070404A (de)
AU (1) AU2280592A (de)
CA (1) CA2077732A1 (de)
HU (1) HUT65204A (de)
IL (1) IL102946A0 (de)
MX (1) MX9205145A (de)
TW (1) TW257763B (de)

Families Citing this family (95)

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US5356897A (en) * 1991-09-09 1994-10-18 Fujisawa Pharmaceutical Co., Ltd. 3-(heteroaryl)-pyrazololi[1,5-a]pyrimidines
GB9303993D0 (en) * 1993-02-26 1993-04-14 Fujisawa Pharmaceutical Co New heterocyclic derivatives
DE69417087T2 (de) * 1993-04-22 1999-07-15 Mitsubishi Chemical Corp., Tokio/Tokyo Wässrige Arzneizubereitungen enthaltend Argatroban und Cyclodextrin oder Coffein
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US6268392B1 (en) 1994-09-13 2001-07-31 G. D. Searle & Co. Combination therapy employing ileal bile acid transport inhibiting benzothiepines and HMG Co-A reductase inhibitors
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FR2750048B1 (fr) * 1996-06-21 1998-08-14 Oreal Compositions de teinture des fibres keratiniques contenant des derives pyrazolo-(1, 5-a)-pyrimidine, procede de teinture, nouveaux derives pyrazolo-(1, 5-a)-pyrimidine et leur procede de preparation
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US6191131B1 (en) 1997-07-23 2001-02-20 Dupont Pharmaceuticals Company Azolo triazines and pyrimidines
US7094782B1 (en) 1996-07-24 2006-08-22 Bristol-Myers Squibb Company Azolo triazines and pyrimidines
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US6124289A (en) * 1996-07-24 2000-09-26 Dupont Pharmaceuticals Co. Azolo triazines and pyrimidines
HU229024B1 (en) * 1996-07-24 2013-07-29 Bristol Myers Squibb Pharma Co Azolo-pyridimidines, pharmaceutical compositions containing the same and use thereof
US6060478A (en) * 1996-07-24 2000-05-09 Dupont Pharmaceuticals Azolo triazines and pyrimidines
AR037061A1 (es) * 1997-05-22 2004-10-20 Searle & Co Compuesto derivado de pirazol sustituido, procesos para preparar dicho compuesto, composicion farmaceutica que lo contiene y su uso en la preparacion de medicamentos
US6979686B1 (en) 2001-12-07 2005-12-27 Pharmacia Corporation Substituted pyrazoles as p38 kinase inhibitors
JP2002502380A (ja) 1997-05-22 2002-01-22 ジー．ディー．サール アンド カンパニー ｐ３８キナーゼ阻害剤としてのピラゾール誘導体
US6514977B1 (en) 1997-05-22 2003-02-04 G.D. Searle & Company Substituted pyrazoles as p38 kinase inhibitors
US6087496A (en) * 1998-05-22 2000-07-11 G. D. Searle & Co. Substituted pyrazoles suitable as p38 kinase inhibitors
US6235741B1 (en) * 1997-05-30 2001-05-22 Merck & Co., Inc. Angiogenesis inhibitors
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AU2006203676B2 (en) * 1999-08-13 2010-04-22 Vertex Pharmaceuticals Incorporated Inhibitors of c-JUN N-Terminal Kinases (JNK) and Other Protein Kinases
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US6472416B1 (en) 1999-08-27 2002-10-29 Abbott Laboratories Sulfonylphenylpyrazole compounds useful as COX-2 inhibitors
WO2001015525A1 (en) * 1999-08-31 2001-03-08 Fujisawa Pharmaceutical Co., Ltd. Organ preservatives
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DE10153344A1 (de) * 2001-10-29 2003-05-15 Gruenenthal Gmbh Verwendung von substituierten Pyrazolopyrimidinen als Liganden von Nucleosid-Transport-Proteinen und/oder von Purinorezeptoren
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AU2002359160A1 (en) * 2001-12-20 2003-07-09 Biovitrum Ab PIPAZOLO (1,5-a) PYRIMIDINE DERIVATIVES AS MODULATORS OF PPAR
AU2003207431A1 (en) 2002-01-17 2003-09-02 Pharmacia Corporation Novel alkyl/aryl hydroxy or keto thiepines.
ATE365740T1 (de) * 2002-05-10 2007-07-15 Smithkline Beecham Corp Substituierte pyrazolopyrimidine
CZ20023575A3 (cs) * 2002-10-25 2004-01-14 Léčiva, A.S. Způsob výroby N-ethyl-N-[3-(3-methyl-pyrazolo[1,5-a]pyrimidin-7-yl)-fenyl]-acetamidu (zaleplonu)
CA2506799A1 (en) * 2002-11-21 2004-06-10 Eli Lilly And Company Mixed lineage kinase modulators
UA80571C2 (en) * 2002-11-22 2007-10-10 Lilly Co Eli Quinolinyl-pyrrolopyrazoles
WO2004110454A1 (ja) * 2003-06-13 2004-12-23 Ishihara Sangyo Kaisha, Ltd. アデノシンＡ2ａ受容体アゴニストの投与が必要な疾患を治療又は予防するための組成物
DE10332487A1 (de) * 2003-07-16 2005-02-10 Boehringer Ingelheim Pharma Gmbh & Co. Kg Ambroxol für die Behandlung von chronisch nozizeptiven Schmerzen
US7511065B2 (en) 2003-11-12 2009-03-31 Eli Lilly And Company Mixed lineage kinase modulators
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US7608635B2 (en) 2005-08-12 2009-10-27 Synta Pharmaceuticals Corp. Pyrazole compounds that modulate HSP90 activity
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WO2007129195A2 (en) * 2006-05-04 2007-11-15 Pfizer Products Inc. 4-pyrimidine-5-amino-pyrazole compounds
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US8809344B2 (en) 2008-10-29 2014-08-19 Apath, Llc Compounds, compositions, and methods for control of hepatitis C viral infections
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EP2402344A1 (de) * 2010-06-29 2012-01-04 Basf Se Pyrazolkondensierte bicyclische Verbindungen
EP2402345A1 (de) * 2010-06-29 2012-01-04 Basf Se Pyrazole kondensierte bizyclische Verbindungen
EP2402339A1 (de) * 2010-06-29 2012-01-04 Basf Se Pyrazolopyridin-Verbindungen
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JP2014534228A (ja) 2011-11-02 2014-12-18 シンタ ファーマシューティカルズ コーポレーション 白金含有剤とｈｓｐ９０阻害剤の組合せ療法
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BR112015022096A8 (pt) 2013-03-15 2019-11-26 Chromocell Corp compostos moduladores de canal de sódio, composição que os compreende e uso dos mesmos
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CN105611923B (zh) 2013-09-10 2019-08-23 卓莫赛尔公司 用于治疗疼痛和糖尿病的钠通道调节剂
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BR112016022105B1 (pt) 2014-03-27 2023-01-31 Janssen Pharmaceutica Nv Derivados de 4,5,6,7-tetra-hidro-pirazolo[1,5- a]pirazina substituídos e derivados de 5,6,7,8-tetrahidro-4h-pirazolo[1,5-a][1,4]diazepina como inibidores do ros1 e composição farmacêutica que os compreende
CN104140427A (zh) * 2014-07-05 2014-11-12 湖南华腾制药有限公司 一种四氢吡唑并[1,5-a]嘧啶的制备方法
WO2016040315A1 (en) * 2014-09-09 2016-03-17 Chromocell Corporation Selective nav1.7 inhibitors for the treatment of diabetes
KR102384652B1 (ko) * 2015-02-03 2022-04-27 솔루스첨단소재 주식회사 유기 화합물 및 이를 포함하는 유기 전계 발광 소자
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WO2020163689A1 (en) 2019-02-08 2020-08-13 University Of Pittsburgh - Of The Commonwealth System Of Higher Education 20-hete formation inhibitors
MX2022006865A (es) 2019-12-06 2022-07-11 Vertex Pharma Tetrahidrofuranos sustituidos como moduladores de canales de sodio.
BR112022022437A2 (pt) * 2020-05-07 2023-01-03 Adorx Therapeutics Ltd Antagonistas do receptor a2a de adenosina
MX2023001688A (es) * 2020-08-12 2023-02-22 Spruce Biosciences Inc Metodos y composiciones para tratar el sindrome de ovario poliquistico.
CN117794920A (zh) 2021-06-04 2024-03-29 沃泰克斯药物股份有限公司 N-(羟烷基(杂)芳基)四氢呋喃甲酰胺作为钠通道调节剂
JP2025513455A (ja) 2022-04-22 2025-04-24 バーテックス ファーマシューティカルズ インコーポレイテッド 疼痛の治療のためのヘテロアリール化合物

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US5356897A (en) * 1991-09-09 1994-10-18 Fujisawa Pharmaceutical Co., Ltd. 3-(heteroaryl)-pyrazololi[1,5-a]pyrimidines

Also Published As

Publication number Publication date
HU9202877D0 (en) 1992-11-30
US5624931A (en) 1997-04-29
EP0531901A2 (de) 1993-03-17
EP0531901A3 (de) 1993-05-05
TW257763B (de) 1995-09-21
JPH06287188A (ja) 1994-10-11
JPH07252256A (ja) 1995-10-03
HUT65204A (en) 1994-05-02
JPH0788386B2 (ja) 1995-09-27
MX9205145A (es) 1993-04-01
US5356897A (en) 1994-10-18
AU2280592A (en) 1993-03-11
US5478827A (en) 1995-12-26
CA2077732A1 (en) 1993-03-10
CN1070404A (zh) 1993-03-31

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Legal Events

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HC Change of name of proprietor(s)