ATE365740T1 - Substituierte pyrazolopyrimidine - Google Patents

Substituierte pyrazolopyrimidine

Info

Publication number
ATE365740T1
ATE365740T1 AT03726540T AT03726540T ATE365740T1 AT E365740 T1 ATE365740 T1 AT E365740T1 AT 03726540 T AT03726540 T AT 03726540T AT 03726540 T AT03726540 T AT 03726540T AT E365740 T1 ATE365740 T1 AT E365740T1
Authority
AT
Austria
Prior art keywords
substituted pyrazolopyrimidines
same
pyrazolopyrimidines
substituted
preparing
Prior art date
Application number
AT03726540T
Other languages
English (en)
Inventor
Kristjan S Gudmundsson
Brian A Johns
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Application granted granted Critical
Publication of ATE365740T1 publication Critical patent/ATE365740T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
AT03726540T 2002-05-10 2003-04-30 Substituierte pyrazolopyrimidine ATE365740T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US37942102P 2002-05-10 2002-05-10

Publications (1)

Publication Number Publication Date
ATE365740T1 true ATE365740T1 (de) 2007-07-15

Family

ID=29420528

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03726540T ATE365740T1 (de) 2002-05-10 2003-04-30 Substituierte pyrazolopyrimidine

Country Status (8)

Country Link
US (1) US7304068B2 (de)
EP (1) EP1504004B1 (de)
JP (1) JP2005529919A (de)
AT (1) ATE365740T1 (de)
AU (1) AU2003228770A1 (de)
DE (1) DE60314623T2 (de)
ES (1) ES2287476T3 (de)
WO (1) WO2003095455A2 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1485385B1 (de) 2002-03-07 2005-08-17 SmithKline Beecham Corporation Pyrazolopyrimidin- und pyrazolotriazinderivate und diese enthaltende pharmazeutische zubereitungen
US7196078B2 (en) 2002-09-04 2007-03-27 Schering Corpoartion Trisubstituted and tetrasubstituted pyrazolopyrimidines as cyclin dependent kinase inhibitors
US7129239B2 (en) 2002-10-28 2006-10-31 Pfizer Inc. Purine compounds and uses thereof
US7247628B2 (en) 2002-12-12 2007-07-24 Pfizer, Inc. Cannabinoid receptor ligands and uses thereof
US7176210B2 (en) 2003-02-10 2007-02-13 Pfizer Inc. Cannabinoid receptor ligands and uses thereof
US7141669B2 (en) 2003-04-23 2006-11-28 Pfizer Inc. Cannabiniod receptor ligands and uses thereof
US7268133B2 (en) 2003-04-23 2007-09-11 Pfizer, Inc. Patent Department Cannabinoid receptor ligands and uses thereof
US7145012B2 (en) 2003-04-23 2006-12-05 Pfizer Inc. Cannabinoid receptor ligands and uses thereof
US7232823B2 (en) 2003-06-09 2007-06-19 Pfizer, Inc. Cannabinoid receptor ligands and uses thereof
FR2859729B1 (fr) * 2003-09-12 2006-02-24 Roquette Freres Dispersions aqueuses d'au moins un polymere biodegradable
TW200639163A (en) 2005-02-04 2006-11-16 Genentech Inc RAF inhibitor compounds and methods
UA103319C2 (en) 2008-05-06 2013-10-10 Глаксосмитклайн Ллк Thiazole- and oxazole-benzene sulfonamide compounds
EP2308866A1 (de) 2009-10-09 2011-04-13 Bayer CropScience AG Phenylpyri(mi)dinylpyrazole und ihre Verwendung als Fungizide
BR112012018358A2 (pt) 2009-12-21 2016-08-09 Bayer Cropscience Ag tienilpiri(mi)dinilazol e seu uso para controlar fungos fitopatogênicos
AR081810A1 (es) 2010-04-07 2012-10-24 Bayer Cropscience Ag Piridinilpirazoles biciclicos
CN102958933B (zh) * 2010-06-24 2016-02-03 吉里德科学公司 作为抗病毒药的吡唑并[1,5-a]嘧啶类
AU2015200638B2 (en) * 2010-06-24 2016-11-10 Gilead Sciences, Inc. Pyrazolo [1, 5 -a] pyrimidines as antiviral agents
EP2402344A1 (de) 2010-06-29 2012-01-04 Basf Se Pyrazolkondensierte bicyclische Verbindungen
EP2402345A1 (de) 2010-06-29 2012-01-04 Basf Se Pyrazole kondensierte bizyclische Verbindungen
EP2402337A1 (de) 2010-06-29 2012-01-04 Basf Se Pyrazolopyridin-Verbindungen
EP2402343A1 (de) 2010-06-29 2012-01-04 Basf Se Pyrazole kondensierte bizyclische Verbindungen
AR086992A1 (es) 2011-06-20 2014-02-05 Bayer Ip Gmbh Tienilpiri(mi)dinilpirazoles
US8633198B1 (en) * 2011-09-20 2014-01-21 Nant Holdings Ip, Llc Small molecule inhibitors of influenza A RNA-dependent RNA polymerase
MX351460B (es) 2011-10-06 2017-10-16 Bayer Ip Gmbh Heterociclilpiri(mi)dinilpirazol.
BR112014008223A2 (pt) * 2011-10-06 2017-04-25 Bayer Ip Gmbh heterociclilpiri (mi) dinilpirazol
EP2794611B1 (de) * 2011-12-22 2017-10-11 Gilead Sciences, Inc. Pyrazol-[1,5-a-]pyrimidine als viruzide
CN104583211A (zh) 2012-04-17 2015-04-29 吉里德科学公司 用于抗病毒治疗的化合物和方法
AU2013407264B2 (en) * 2013-12-11 2016-09-29 Nant Holdings Ip, Llc Small molecule inhibitors of influenza a RNA-dependent RNA polymerase
JP2017501145A (ja) 2013-12-23 2017-01-12 ノージン ビーブイ Ｃｃｒ９調節因子として有用な化合物
WO2015110491A2 (en) * 2014-01-22 2015-07-30 Apodemus Ab Pyrazolo[1,5-a]pyrimidin-7-amine derivatives useful in therapy
US9981976B2 (en) * 2014-12-08 2018-05-29 Janssen Sciences Ireland Uc Piperidine substituted pyrazolo[1,5-A]pyrimidine derivatives with inhibitory activity on the replication of the respiratory syncytial virus (RSV)
CN112996790B (zh) 2018-10-30 2023-11-03 克洛诺斯生物公司 用于调节cdk9活性的化合物、组合物和方法
IL303924A (en) * 2020-12-18 2023-08-01 Scripps Research Inst Compounds and their use for the treatment of neurodegenerative, degenerative and metabolic disorders

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US5356897A (en) 1991-09-09 1994-10-18 Fujisawa Pharmaceutical Co., Ltd. 3-(heteroaryl)-pyrazololi[1,5-a]pyrimidines
JPH11505524A (ja) 1995-05-01 1999-05-21 藤沢薬品工業株式会社 イミダゾ１，２−ａピリジンおよびイミダゾ１，２−ａピリデジン誘導体、および骨吸収阻害剤としてのその用途
US6313124B1 (en) * 1997-07-23 2001-11-06 Dupont Pharmaceuticals Company Tetrazine bicyclic compounds
US6124289A (en) * 1996-07-24 2000-09-26 Dupont Pharmaceuticals Co. Azolo triazines and pyrimidines
US6191131B1 (en) * 1997-07-23 2001-02-20 Dupont Pharmaceuticals Company Azolo triazines and pyrimidines
US6060478A (en) * 1996-07-24 2000-05-09 Dupont Pharmaceuticals Azolo triazines and pyrimidines
RU2249591C2 (ru) * 1997-05-22 2005-04-10 Дж.Д. Серл Энд Ко. 3(5)-гетероарилзамещенные пиразолы в качестве ингибиторов киназы p38
WO1998054093A1 (en) 1997-05-30 1998-12-03 Merck & Co., Inc. Novel angiogenesis inhibitors
JP2000038350A (ja) 1998-05-18 2000-02-08 Yoshitomi Pharmaceut Ind Ltd 糖尿病治療薬
US6770666B2 (en) * 1999-12-27 2004-08-03 Japan Tobacco Inc. Fused-ring compounds and use thereof as drugs
PE20020506A1 (es) 2000-08-22 2002-07-09 Glaxo Group Ltd Derivados de pirazol fusionados como inhibidores de la proteina cinasa
GB0103926D0 (en) 2001-02-17 2001-04-04 Astrazeneca Ab Chemical compounds

Also Published As

Publication number Publication date
JP2005529919A (ja) 2005-10-06
AU2003228770A1 (en) 2003-11-11
DE60314623D1 (de) 2007-08-09
US7304068B2 (en) 2007-12-04
ES2287476T3 (es) 2007-12-16
US20050203106A1 (en) 2005-09-15
AU2003228770A8 (en) 2003-11-11
EP1504004B1 (de) 2007-06-27
WO2003095455A3 (en) 2003-12-24
DE60314623T2 (de) 2008-02-28
WO2003095455A2 (en) 2003-11-20
EP1504004A2 (de) 2005-02-09

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