CA2059693C
(en)
*
|
1991-01-28 |
2003-08-19 |
Peter J. Kniskern |
Polysaccharide antigens from streptococcus pneumoniae
|
US5445817A
(en)
*
|
1992-08-21 |
1995-08-29 |
The United States Of America As Represented By The Department Of Health And Human Services |
Pertussis toxin used as a carrier protein with non-charged saccharides in conjugate vaccines
|
US5439808A
(en)
*
|
1993-07-23 |
1995-08-08 |
North American Vaccine, Inc. |
Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis
|
US5565204A
(en)
*
|
1994-08-24 |
1996-10-15 |
American Cyanamid Company |
Pneumococcal polysaccharide-recombinant pneumolysin conjugate vaccines for immunization against pneumococcal infections
|
US5681570A
(en)
*
|
1995-01-12 |
1997-10-28 |
Connaught Laboratories Limited |
Immunogenic conjugate molecules
|
US5747287A
(en)
*
|
1995-04-28 |
1998-05-05 |
North American Vaccine, Inc. |
Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis
|
EP0831894A1
(en)
*
|
1995-06-07 |
1998-04-01 |
Alberta Research Council |
Immunogenic and immunostimulatory oligosaccharide compositions and methods of making and using them
|
US5695768A
(en)
*
|
1995-06-07 |
1997-12-09 |
Alberta Research Council |
Immunostimulating activity of Streptococcus pneumoniae serotype 8 oligosaccharides
|
US5866132A
(en)
*
|
1995-06-07 |
1999-02-02 |
Alberta Research Council |
Immunogenic oligosaccharide compositions
|
US6410025B1
(en)
|
1996-02-14 |
2002-06-25 |
Merck & Co., Inc. |
Polysaccharide precipitation process
|
SE9601158D0
(sv)
*
|
1996-03-26 |
1996-03-26 |
Stefan Svenson |
Method of producing immunogenic products and vaccines
|
US6207157B1
(en)
|
1996-04-23 |
2001-03-27 |
The United States Of America As Represented By The Department Of Health And Human Services |
Conjugate vaccine for nontypeable Haemophilus influenzae
|
WO1998008543A1
(en)
*
|
1996-08-27 |
1998-03-05 |
Chiron Corporation |
Neisseria meningitidis serogroup b glycoconjugates and methods of using the same
|
FR2763244B1
(fr)
|
1997-05-14 |
2003-08-01 |
Pasteur Merieux Serums Vacc |
Composition vaccinale multivalente a porteur mixte
|
WO1999003884A2
(en)
|
1997-07-21 |
1999-01-28 |
North American Vaccine, Inc. |
Modified immunogenic pneumolysin, compositions and their use as vaccines
|
US6224880B1
(en)
|
1997-09-24 |
2001-05-01 |
Merck & Co., Inc. |
Immunization against Streptococcus pneumoniae using conjugated and unconjugated pneumoccocal polysaccharide vaccines
|
US6756361B1
(en)
*
|
1997-10-14 |
2004-06-29 |
Nabi |
Enterococcus antigens and vaccines
|
GB9727262D0
(en)
*
|
1997-12-24 |
1998-02-25 |
Smithkline Beecham Biolog |
Vaccine
|
CA2320223A1
(en)
*
|
1998-02-12 |
1999-08-19 |
American Cyanamid Company |
Pneumococcal and meningococcal vaccines formulated with interleukin-12
|
US7018637B2
(en)
*
|
1998-02-23 |
2006-03-28 |
Aventis Pasteur, Inc |
Multi-oligosaccharide glycoconjugate bacterial meningitis vaccines
|
JP2002513028A
(ja)
*
|
1998-04-28 |
2002-05-08 |
ガレニカ ファーマシューティカルズ, インコーポレイテッド |
ポリサッカリド抗原結合体
|
GB9816337D0
(en)
*
|
1998-07-27 |
1998-09-23 |
Cortecs Uk Ltd |
Proteins
|
US20080096236A1
(en)
*
|
1998-08-25 |
2008-04-24 |
Binax, Inc. |
Method for Detecting the Presence of Target Bacteria or a Target Component Carbohydrate Antigen Thereof
|
US9134303B1
(en)
|
1998-08-25 |
2015-09-15 |
Alere Scarborough, Inc. |
ICT immunoassay for Legionella pneumophila serogroup 1 antigen employing affinity purified antibodies thereto
|
US6824997B1
(en)
*
|
1998-09-18 |
2004-11-30 |
Binax, Inc. |
Process and materials for the rapid detection of streptococcus pneumoniae employing purified antigen-specific antibodies
|
US6146902A
(en)
*
|
1998-12-29 |
2000-11-14 |
Aventis Pasteur, Inc. |
Purification of polysaccharide-protein conjugate vaccines by ultrafiltration with ammonium sulfate solutions
|
GB9906437D0
(en)
*
|
1999-03-19 |
1999-05-12 |
Smithkline Beecham Biolog |
Vaccine
|
HU228499B1
(en)
*
|
1999-03-19 |
2013-03-28 |
Smithkline Beecham Biolog |
Streptococcus vaccine
|
US20040191834A1
(en)
*
|
1999-10-28 |
2004-09-30 |
Laferriere Craig Antony Joseph |
Novel method
|
CZ20024224A3
(cs)
*
|
2000-06-29 |
2003-05-14 |
Glaxosmithkline Biologicals S. A. |
Farmaceutický prostředek
|
GB0108364D0
(en)
|
2001-04-03 |
2001-05-23 |
Glaxosmithkline Biolog Sa |
Vaccine composition
|
GB0022742D0
(en)
*
|
2000-09-15 |
2000-11-01 |
Smithkline Beecham Biolog |
Vaccine
|
GB0115176D0
(en)
*
|
2001-06-20 |
2001-08-15 |
Chiron Spa |
Capular polysaccharide solubilisation and combination vaccines
|
EP1569955A2
(en)
*
|
2002-12-03 |
2005-09-07 |
Sloan-Kettering Institute For Cancer Research |
Gp120 specific antigens, conjugates thereof, methods for their preparation and uses thereof
|
US7369578B2
(en)
*
|
2003-07-01 |
2008-05-06 |
Nortel Networks Limited |
Digital processing of SONET pointers
|
SG182163A1
(en)
*
|
2003-12-17 |
2012-07-30 |
Wyeth Corp |
Immunogenic peptide carrier conjugates and methods of producing same
|
MY144231A
(en)
*
|
2003-12-17 |
2011-08-15 |
Wyeth Corp |
Aß IMMUNOGENIC PEPTIDE CARRIER CONJUGATES AND METHODS OF PRODUCING SAME
|
NZ553776A
(en)
|
2004-09-22 |
2010-05-28 |
Glaxosmithkline Biolog Sa |
Immunogenic composition comprising staphylococcal PNAG and Type 5 and/or 8 Capsular polysaccharide or oligosaccharide.
|
AU2011253684B8
(en)
*
|
2005-04-08 |
2013-07-11 |
Wyeth Llc |
Multivalent pneumococcal polysaccharide-protein conjugate composition
|
US20070184072A1
(en)
*
|
2005-04-08 |
2007-08-09 |
Wyeth |
Multivalent pneumococcal polysaccharide-protein conjugate composition
|
US7709001B2
(en)
*
|
2005-04-08 |
2010-05-04 |
Wyeth Llc |
Multivalent pneumococcal polysaccharide-protein conjugate composition
|
US7955605B2
(en)
|
2005-04-08 |
2011-06-07 |
Wyeth Llc |
Multivalent pneumococcal polysaccharide-protein conjugate composition
|
IL308456A
(en)
*
|
2005-04-08 |
2024-01-01 |
Wyeth Llc |
A multivalent pneumomuroral protein-polysaccharide conjugate preparation
|
PT1896065E
(pt)
|
2005-06-27 |
2011-08-31 |
Glaxosmithkline Biolog Sa |
Processo para a preparação de vacinas
|
TWI457133B
(zh)
|
2005-12-13 |
2014-10-21 |
Glaxosmithkline Biolog Sa |
新穎組合物
|
GB0607088D0
(en)
|
2006-04-07 |
2006-05-17 |
Glaxosmithkline Biolog Sa |
Vaccine
|
EP3020411A1
(en)
*
|
2005-12-22 |
2016-05-18 |
GlaxoSmithKline Biologicals s.a. |
Vaccine
|
CN101024079B
(zh)
*
|
2006-02-17 |
2012-02-01 |
福州昌晖生物工程有限公司 |
肺炎链球菌多糖-外膜蛋白结合疫苗及制备方法
|
EP1998802A2
(en)
|
2006-03-30 |
2008-12-10 |
GlaxoSmithKline Biologicals S.A. |
Immunogenic composition
|
AU2013200552B9
(en)
*
|
2006-04-07 |
2014-07-03 |
Glaxosmithkline Biologicals S.A. |
Conjugate vaccines
|
TW200806315A
(en)
*
|
2006-04-26 |
2008-02-01 |
Wyeth Corp |
Novel formulations which stabilize and inhibit precipitation of immunogenic compositions
|
US8808707B1
(en)
|
2006-05-08 |
2014-08-19 |
Wyeth Llc |
Pneumococcal dosing regimen
|
ZA200900899B
(en)
*
|
2006-08-07 |
2010-07-28 |
Harvard College |
Protein matrix vaccines and methods of making and administering such vaccines
|
WO2008028957A2
(en)
|
2006-09-07 |
2008-03-13 |
Glaxosmithkline Biologicals S.A. |
Vaccine
|
AU2007307800C1
(en)
*
|
2006-10-10 |
2014-03-13 |
Wyeth Llc |
Purification of Streptococcus pneumoniae type 3 polysaccharides
|
CN1963500B
(zh)
*
|
2006-12-06 |
2010-05-12 |
云南沃森生物技术股份有限公司 |
一种肺炎链球菌荚膜多糖结合物中游离多糖含量的测定方法
|
GB0700136D0
(en)
|
2007-01-04 |
2007-02-14 |
Glaxosmithkline Biolog Sa |
Process for manufacturing vaccines
|
MY150927A
(en)
*
|
2007-03-23 |
2014-03-14 |
Wyeth Corp |
Shortened purification process for the production of capsular streptococcus pneumoniae polysaccharides
|
EP2155244B1
(en)
|
2007-04-23 |
2017-03-22 |
Serum Institute of India Private Limited |
Antigenic polysaccharides and process for their preparation
|
EA201490303A1
(ru)
|
2007-05-02 |
2014-05-30 |
Глаксосмитклайн Байолоджикалс С.А. |
Вакцина
|
PT2167121E
(pt)
|
2007-06-26 |
2015-12-02 |
Glaxosmithkline Biolog Sa |
Vacina compreendendo conjugados de polissacáridos capsulares de streptococcus pneumoniae
|
CA2739581A1
(en)
|
2008-10-06 |
2010-04-15 |
University Of Chicago |
Compositions and methods related to bacterial eap, emp, and/or adsa proteins
|
KR20110091546A
(ko)
*
|
2008-12-18 |
2011-08-11 |
와이어쓰 엘엘씨 |
스트렙토코커스 뉴모니에 혈청형 19a 폴리사카라이드 분자량을 조절하는 방법
|
SI2385981T1
(sl)
|
2008-12-18 |
2019-11-29 |
Wyeth Llc |
Postopek za nadzorovanje molekulske mase polisaharida streptococcus pneumoniae z uporabo ogljika
|
WO2010083477A2
(en)
|
2009-01-16 |
2010-07-22 |
University Of Maryland, Baltimore |
Broad spectrum vaccine against non-typhoidal salmonella
|
WO2011005341A2
(en)
|
2009-04-03 |
2011-01-13 |
University Of Chicago |
Compositions and methods related to protein a (spa) variants
|
WO2010141312A2
(en)
|
2009-06-01 |
2010-12-09 |
Wake Forest University Health Sciences |
Flagellin fusion proteins and conjugates comprising pneumococcus antigens and methods of using the same
|
BRPI1011919A2
(pt)
*
|
2009-06-29 |
2017-09-26 |
Childrens Medical Center |
vacinas e composições contra streptococcus pneumoniae
|
GB0913681D0
(en)
|
2009-08-05 |
2009-09-16 |
Glaxosmithkline Biolog Sa |
Immunogenic composition
|
GB0913680D0
(en)
|
2009-08-05 |
2009-09-16 |
Glaxosmithkline Biolog Sa |
Immunogenic composition
|
GB201003922D0
(en)
|
2010-03-09 |
2010-04-21 |
Glaxosmithkline Biolog Sa |
Conjugation process
|
GB201003924D0
(en)
|
2010-03-09 |
2010-04-21 |
Glaxosmithkline Biolog Sa |
Immunogenic composition
|
JP2013523818A
(ja)
|
2010-04-05 |
2013-06-17 |
ザ・ユニバーシティー・オブ・シカゴ |
免疫反応のエンハンサーとしてのプロテインA(SpA)抗体に関連する組成物および方法
|
WO2011148382A1
(en)
|
2010-05-28 |
2011-12-01 |
Biological E Limited |
An improved process for the purification of capsular polysaccharides of haemophilus influenza - b, neisseria meningitis such as serotypes a, c, y and w-135, and other similar related capsular polysaccharides produced from both gram negative and gram positive microorganisms using aluminium phosphate with alcohol.
|
CA2803298C
(en)
|
2010-07-02 |
2020-07-14 |
The University Of Chicago |
Compositions and methods related to protein a (spa) variants
|
US9095540B2
(en)
|
2010-09-09 |
2015-08-04 |
The University Of Chicago |
Methods and compositions involving protective staphylococcal antigens
|
WO2012100234A1
(en)
*
|
2011-01-20 |
2012-07-26 |
Genocea Biosciences, Inc. |
Vaccines and compositions against streptococcus pneumoniae
|
GB201103836D0
(en)
|
2011-03-07 |
2011-04-20 |
Glaxosmithkline Biolog Sa |
Conjugation process
|
CN103687600B
(zh)
|
2011-03-22 |
2016-05-04 |
印度血清研究所私人有限公司 |
一种制备多糖的方法
|
US8945588B2
(en)
|
2011-05-06 |
2015-02-03 |
The University Of Chicago |
Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides
|
DE202012012768U1
(de)
|
2011-12-06 |
2014-01-21 |
Valneva Austria Gmbh |
Aluminium-Verbindungen zur Verwendung in Therapeutika und Impfstoffen
|
WO2013109995A2
(en)
|
2012-01-20 |
2013-07-25 |
Genocea Biosciences, Inc. |
Fused antigen vaccines and compositions against streptococcus pneumoniae
|
BR112014026861A2
(pt)
|
2012-04-26 |
2018-05-15 |
Univ Chicago |
antígenos de estafilococos coagulase e métodos de seu uso
|
ITMI20121597A1
(it)
*
|
2012-09-25 |
2014-03-26 |
Beta Pharma S A |
Coniugato tra frammento di parete cellulare batterica ed un veicolo mucopolisaccaridico e suoi usi in ambito medico
|
WO2014124228A1
(en)
|
2013-02-07 |
2014-08-14 |
Children's Medical Center Corporation |
Protein antigens that provide protection against pneumococcal colonization and/or disease
|
EP3019513B1
(en)
*
|
2013-07-07 |
2018-01-17 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Synthetic vaccines against streptococcus pneumoniae type 1
|
US11708411B2
(en)
|
2013-12-20 |
2023-07-25 |
Wake Forest University Health Sciences |
Methods and compositions for increasing protective antibody levels induced by pneumococcal polysaccharide vaccines
|
KR102157200B1
(ko)
*
|
2014-01-21 |
2020-09-21 |
화이자 인코포레이티드 |
접합된 캡슐 사카라이드 항원을 포함하는 면역원성 조성물 및 그의 용도
|
PL3583947T3
(pl)
*
|
2014-01-21 |
2024-04-02 |
Pfizer Inc. |
Polisacharydy otoczkowe streptococcus pneumoniae i ich koniugaty
|
US11160855B2
(en)
|
2014-01-21 |
2021-11-02 |
Pfizer Inc. |
Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof
|
EP3104886B1
(en)
*
|
2014-02-14 |
2018-10-17 |
Pfizer Inc |
Immunogenic glycoprotein conjugates
|
US9815886B2
(en)
|
2014-10-28 |
2017-11-14 |
Adma Biologics, Inc. |
Compositions and methods for the treatment of immunodeficiency
|
EA201792470A1
(ru)
|
2015-06-08 |
2018-10-31 |
Серум Инститьют Оф Индия Прайват Лтд. |
Способы улучшения адсорбции полисахарид-белковых конъюгатов и полученная из них композиция поливалентной вакцины
|
WO2017173415A2
(en)
|
2016-03-31 |
2017-10-05 |
Liffey Biotech Limited |
Saccharide-polypeptide conjugate compositions and methods of use thereof
|
EP3269385A1
(en)
|
2016-07-12 |
2018-01-17 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Pneumococcal polysaccharide-protein conjugate composition
|
WO2017220753A1
(en)
|
2016-06-22 |
2017-12-28 |
MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. |
Pneumococcal polysaccharide-protein conjugate composition
|
US11951165B2
(en)
|
2016-12-30 |
2024-04-09 |
Vaxcyte, Inc. |
Conjugated vaccine carrier proteins
|
CN118662649A
(zh)
|
2016-12-30 |
2024-09-20 |
Vaxcyte公司 |
具有非天然氨基酸的多肽-抗原缀合物
|
WO2018144438A1
(en)
|
2017-01-31 |
2018-08-09 |
Merck Sharp & Dohme Corp. |
Methods for production of capsular polysaccharide protein conjugates from streptococcus pneumoniae serotype 19f
|
CA3052621A1
(en)
|
2017-02-03 |
2018-08-09 |
Schadeck, Eva Barbara |
Haemophilus influenzae saccharide-carrier conjugate compositions and uses thereof
|
US20200061542A1
(en)
*
|
2017-02-24 |
2020-02-27 |
Merck Sharp & Dohme Corp. |
Methods for improving filterability of polysaccharide-protein conjugate reactions
|
US11400162B2
(en)
|
2017-02-24 |
2022-08-02 |
Merck Sharp & Dohme Llc |
Processes for the formulation of pneumococcal polysaccharides for conjugation to a carrier protein
|
US10259865B2
(en)
|
2017-03-15 |
2019-04-16 |
Adma Biologics, Inc. |
Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection
|
WO2018227177A1
(en)
|
2017-06-10 |
2018-12-13 |
Inventprise, Llc |
Multivalent conjugate vaccines with bivalent or multivalent conjugate polysaccharides that provide improved immunogenicity and avidity
|
US10729763B2
(en)
|
2017-06-10 |
2020-08-04 |
Inventprise, Llc |
Mixtures of polysaccharide-protein pegylated compounds
|
CN116898959A
(zh)
|
2017-09-07 |
2023-10-20 |
默沙东有限责任公司 |
肺炎球菌多糖及其在免疫原性多糖-载体蛋白缀合物中的用途
|
US11524076B2
(en)
|
2017-09-07 |
2022-12-13 |
Merck Sharp & Dohme Llc |
Pneumococcal polysaccharides and their use in immunogenic polysaccharide-carrier protein conjugates
|
BR112020004502A8
(pt)
|
2017-09-07 |
2022-11-01 |
Merck Sharp & Dohme |
Polissacarídeos pneumocócicos e uso dos mesmos em conjugados imunogênicos polissacarídeo-proteína carreadora
|
WO2019050814A1
(en)
|
2017-09-07 |
2019-03-14 |
Merck Sharp & Dohme Corp. |
ANTI-PNEUMOCOCCAL POLYSACCHARIDES AND THEIR USE IN IMMUNOGENIC CONJUGATES POLYSACCHARIDE-PROTEIN CARRIER
|
KR20200051004A
(ko)
|
2017-09-07 |
2020-05-12 |
머크 샤프 앤드 돔 코포레이션 |
폐렴구균 폴리사카라이드 및 면역원성 폴리사카라이드-담체 단백질 접합체에서의 그의 용도
|
CN111683678B
(zh)
|
2017-12-06 |
2024-01-26 |
默沙东有限责任公司 |
包含肺炎链球菌多糖蛋白缀合物的组合物及其使用方法
|
CN108079286B
(zh)
*
|
2018-01-19 |
2020-07-31 |
云南沃森生物技术股份有限公司 |
一种13价肺炎球菌多糖-蛋白结合物组合物及其制备方法和应用
|
US11530432B2
(en)
|
2018-03-19 |
2022-12-20 |
Northwestern University |
Compositions and methods for rapid in vitro synthesis of bioconjugate vaccines in vitro via production and N-glycosylation of protein carriers in detoxified prokaryotic cell lysates
|
SG11202106541WA
(en)
|
2018-12-19 |
2021-07-29 |
Merck Sharp & Dohme |
Compositions comprising streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof
|
CN113966234A
(zh)
|
2019-05-10 |
2022-01-21 |
葛兰素史克生物有限公司 |
缀合物的产生
|
WO2021099982A1
(en)
|
2019-11-22 |
2021-05-27 |
Glaxosmithkline Biologicals Sa |
Dosage and administration of a bacterial saccharide glycoconjugate vaccine
|
EP3900739A1
(en)
|
2020-04-21 |
2021-10-27 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Synthetic streptococcus pneumoniae saccharide conjugates to conserved membrane protein
|
EP3919076A1
(en)
|
2020-06-02 |
2021-12-08 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Synthetic oligosaccharide vaccines against streptococcus pneumoniae with microparticle adjuvant formulations
|
WO2021250626A2
(en)
|
2020-06-12 |
2021-12-16 |
Glaxosmithkline Biologicals Sa |
Dock tag system
|
WO2022035816A1
(en)
|
2020-08-10 |
2022-02-17 |
Inventprise, Llc |
Multivalent pneumococcal glycoconjugate vaccines containing emerging serotype 24f
|
TW202245835A
(zh)
|
2021-02-04 |
2022-12-01 |
美商默沙東有限責任公司 |
用於肺炎球菌結合物疫苗之奈米乳化液佐劑組合物
|
EP4297776A1
(en)
|
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