DE68915046T2 - Haemophilus influenzae Typ B Polysaccharid-Aussermembranprotein-Konjugat als Impfstoff. - Google Patents

Haemophilus influenzae Typ B Polysaccharid-Aussermembranprotein-Konjugat als Impfstoff.

Info

Publication number
DE68915046T2
DE68915046T2 DE68915046T DE68915046T DE68915046T2 DE 68915046 T2 DE68915046 T2 DE 68915046T2 DE 68915046 T DE68915046 T DE 68915046T DE 68915046 T DE68915046 T DE 68915046T DE 68915046 T2 DE68915046 T2 DE 68915046T2
Authority
DE
Germany
Prior art keywords
influenzae type
outer membrane
membrane protein
vaccine
daltons
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68915046T
Other languages
English (en)
Other versions
DE68915046D1 (de
Inventor
Joseph S-C Kuo
James Edwin Bristol
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of DE68915046D1 publication Critical patent/DE68915046D1/de
Publication of DE68915046T2 publication Critical patent/DE68915046T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/102Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
DE68915046T 1988-04-19 1989-03-21 Haemophilus influenzae Typ B Polysaccharid-Aussermembranprotein-Konjugat als Impfstoff. Expired - Fee Related DE68915046T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US18320688A 1988-04-19 1988-04-19

Publications (2)

Publication Number Publication Date
DE68915046D1 DE68915046D1 (de) 1994-06-09
DE68915046T2 true DE68915046T2 (de) 1994-12-08

Family

ID=22671900

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68915046T Expired - Fee Related DE68915046T2 (de) 1988-04-19 1989-03-21 Haemophilus influenzae Typ B Polysaccharid-Aussermembranprotein-Konjugat als Impfstoff.

Country Status (6)

Country Link
EP (1) EP0338265B1 (de)
JP (1) JPH0276824A (de)
AT (1) ATE105189T1 (de)
AU (1) AU627455B2 (de)
DE (1) DE68915046T2 (de)
ES (1) ES2051909T3 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2006587C (en) * 1988-12-23 2000-01-18 Robert W. Tolan Membrane proteins and peptides of haemophilus influenzae type b
SE466259B (sv) * 1990-05-31 1992-01-20 Arne Forsgren Protein d - ett igd-bindande protein fraan haemophilus influenzae, samt anvaendning av detta foer analys, vacciner och uppreningsaendamaal
ATE176989T1 (de) * 1990-12-21 1999-03-15 Antex Biolog Inc Adhesin-oligosaccharid-impfstoffkonjugate für - i(haemophilus influenza)
US5843463A (en) * 1990-12-21 1998-12-01 Antexbiologics, Inc. Adhesin-oligosaccharide conjugate vaccine for Haemophilus influenzae
CA2059692C (en) * 1991-01-28 2004-11-16 Peter J. Kniskern Pneumoccoccal polysaccharide conjugate vaccine
CA2059693C (en) * 1991-01-28 2003-08-19 Peter J. Kniskern Polysaccharide antigens from streptococcus pneumoniae
JP2805174B2 (ja) * 1992-06-22 1998-09-30 アンテックス バイオロジックス,インコーポレーテッド ヘモフィルス・インフルエンザ用アドヘシン−オリゴ糖複合体ワクチン
US5439808A (en) * 1993-07-23 1995-08-08 North American Vaccine, Inc. Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis
AUPM322393A0 (en) * 1993-12-24 1994-01-27 Austin Research Institute, The Mucin carbohydrate compounds and their use in immunotherapy
US5681570A (en) * 1995-01-12 1997-10-28 Connaught Laboratories Limited Immunogenic conjugate molecules
US5747287A (en) * 1995-04-28 1998-05-05 North American Vaccine, Inc. Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis
PL338146A1 (en) * 1997-07-17 2000-09-25 North American Vaccine Immunogenic complex combinations consisting of meningococcal porine of b group and h. influenzae polysaccharide
US11246918B2 (en) 2017-02-03 2022-02-15 Eva Barbara Schadeck Haemophilus influenzae saccharide-carrier conjugate compositions and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4356170A (en) * 1981-05-27 1982-10-26 Canadian Patents & Development Ltd. Immunogenic polysaccharide-protein conjugates
US4673574A (en) * 1981-08-31 1987-06-16 Anderson Porter W Immunogenic conjugates
US4451446A (en) * 1982-03-04 1984-05-29 Smithkline-Rit Process for the preparation of polysaccharide-protein complexes from bacterial capsules, obtained products and immunogenic compositions containing them
US4623574A (en) * 1985-01-14 1986-11-18 Allied Corporation Ballistic-resistant composite article
US4707543A (en) * 1985-09-17 1987-11-17 The United States Of America As Represented By The Secretary Of The Army Process for the preparation of detoxified polysaccharide-outer membrane protein complexes, and their use as antibacterial vaccines
NZ223009A (en) * 1986-12-31 1990-06-26 Nl Rivm Of Thoven Oligosaccharides containing d-ribose d-ribitol and phosphate units mimicing haemophilus influenzae type b antigens

Also Published As

Publication number Publication date
EP0338265B1 (de) 1994-05-04
AU627455B2 (en) 1992-08-27
JPH0276824A (ja) 1990-03-16
DE68915046D1 (de) 1994-06-09
EP0338265A2 (de) 1989-10-25
AU3313789A (en) 1989-10-26
ATE105189T1 (de) 1994-05-15
EP0338265A3 (en) 1989-12-13
ES2051909T3 (es) 1994-07-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee