IE913879A1 - Use of xanthines for the preparation of a medicament¹effective for inhibiting the replication of human¹retroviruses - Google Patents

Use of xanthines for the preparation of a medicament¹effective for inhibiting the replication of human¹retroviruses

Info

Publication number
IE913879A1
IE913879A1 IE387991A IE387991A IE913879A1 IE 913879 A1 IE913879 A1 IE 913879A1 IE 387991 A IE387991 A IE 387991A IE 387991 A IE387991 A IE 387991A IE 913879 A1 IE913879 A1 IE 913879A1
Authority
IE
Ireland
Prior art keywords
formula
group
xanthines
hiv
compounds
Prior art date
Application number
IE387991A
Other languages
English (en)
Original Assignee
Hoechst Roussel Pharma
Dana Farber Cancer Inst Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma, Dana Farber Cancer Inst Inc filed Critical Hoechst Roussel Pharma
Publication of IE913879A1 publication Critical patent/IE913879A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IE387991A 1990-11-07 1991-11-06 Use of xanthines for the preparation of a medicament¹effective for inhibiting the replication of human¹retroviruses IE913879A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US61023090A 1990-11-07 1990-11-07

Publications (1)

Publication Number Publication Date
IE913879A1 true IE913879A1 (en) 1992-05-20

Family

ID=24444220

Family Applications (1)

Application Number Title Priority Date Filing Date
IE387991A IE913879A1 (en) 1990-11-07 1991-11-06 Use of xanthines for the preparation of a medicament¹effective for inhibiting the replication of human¹retroviruses

Country Status (16)

Country Link
EP (1) EP0484785B1 (enExample)
JP (1) JPH054922A (enExample)
KR (1) KR920009397A (enExample)
AT (1) ATE138266T1 (enExample)
AU (1) AU649278B2 (enExample)
CA (1) CA2055041A1 (enExample)
DE (1) DE69119700T2 (enExample)
DK (1) DK0484785T3 (enExample)
ES (1) ES2087205T3 (enExample)
GR (1) GR3020017T3 (enExample)
HU (1) HUT61468A (enExample)
IE (1) IE913879A1 (enExample)
IL (1) IL99966A0 (enExample)
PT (1) PT99434A (enExample)
TW (1) TW209169B (enExample)
ZA (1) ZA918801B (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE59304710D1 (de) * 1992-02-22 1997-01-23 Hoechst Ag Verwendung von Xanthinderivaten zur Behandlung von Muskelschädigungen nach vollständiger Unterbrechung der Blutzirkulation
JP2004525109A (ja) 2001-02-15 2004-08-19 キング・ファーマシューティカルズ・インコーポレイティッド 安定化された甲状腺ホルモン医薬組成物、及びその製法
US7101569B2 (en) 2001-08-14 2006-09-05 Franz G Andrew Methods of administering levothyroxine pharmaceutical compositions
ES2275400B1 (es) * 2005-04-20 2008-04-01 Universidad Autonoma De Madrid Uso de compuestos agonistas de la actividad tubulina desacetilasa de la proteina hdac6 en la elaboracion de composiciones farmaceuticas, dichas composiciones farmaceuticas y sus aplicaciones en el tratamiento de infecciones virales.
WO2009108383A2 (en) 2008-02-29 2009-09-03 Concert Pharmaceuticals, Inc. Substituted xanthine derivatives
US20110053961A1 (en) 2009-02-27 2011-03-03 Concert Pharmaceuticals, Inc. Substituted xanthine derivatives
WO2011028835A1 (en) 2009-09-02 2011-03-10 Concert Pharmaceuticals, Inc. Substituted xanthine derivatives
EP2611807A2 (en) 2010-09-01 2013-07-10 Concert Pharmaceuticals Inc. Polymorphs of (s)-1-(4,4,6,6,6-pentadeutero-5-hydroxyhexyl)-3-7-dimethyl-1h-purine-2,6(3h,7h)dione
WO2013013052A1 (en) 2011-07-19 2013-01-24 Concert Pharmaceuticals, Inc. Substituted xanthine derivatives
MX2014012384A (es) 2012-04-13 2014-11-26 Concert Pharmaceuticals Inc Derivados sustituidos de xantina.
WO2013159006A1 (en) 2012-04-20 2013-10-24 Concert Pharmaceuticals, Inc. Polymorphs of (s)-1-(4,4,6,6,6-pentadeutero-5-hydroxyhexyl)-3,7-dimethyl-1h-purine-2,6(3h,7h)-dione

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3737433A (en) * 1964-09-05 1973-06-05 Albert Ag Chem Werke Certain oxoalkyldimethylxanthines
CH608236A5 (enExample) * 1974-01-22 1978-12-29 Wuelfing J A Fa
US4663317A (en) * 1984-04-18 1987-05-05 Board Of Regents, University Of Texas System Methods and compositions for treating viral infections
US4636507A (en) * 1984-04-30 1987-01-13 Hoechst-Roussel Pharmaceuticals Inc. Host defense mechanism enhancement
DE3525801A1 (de) * 1985-07-19 1987-01-22 Hoechst Ag Tertiaere hydroxyalkylxanthine, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung
GB8610136D0 (en) * 1986-04-25 1986-05-29 Wellcome Found Compounds
DE3725554A1 (de) * 1987-08-01 1989-02-09 Hoechst Ag Pharmazeutisches kombinationspraeparat sowie dessen herstellung und verwendung

Also Published As

Publication number Publication date
CA2055041A1 (en) 1992-05-08
DE69119700T2 (de) 1996-11-07
TW209169B (enExample) 1993-07-11
ZA918801B (en) 1992-12-30
HUT61468A (en) 1993-01-28
AU8699891A (en) 1992-05-14
AU649278B2 (en) 1994-05-19
JPH054922A (ja) 1993-01-14
EP0484785B1 (en) 1996-05-22
DE69119700D1 (de) 1996-06-27
ES2087205T3 (es) 1996-07-16
ATE138266T1 (de) 1996-06-15
EP0484785A2 (en) 1992-05-13
EP0484785A3 (en) 1992-12-16
GR3020017T3 (en) 1996-08-31
KR920009397A (ko) 1992-06-25
PT99434A (pt) 1992-09-30
IL99966A0 (en) 1992-08-18
HU913502D0 (en) 1992-01-28
DK0484785T3 (da) 1996-09-23

Similar Documents

Publication Publication Date Title
EP0277151B1 (en) Novel medicinal use of nucleosides
JP4121151B2 (ja) 抗新生物薬および抗レトロウイルス薬として有用なアクリドンから誘導された化合物
NO178111B (no) Analogifremgangsmåte ved fremstilling av nye, terapeutisk aktive xantin-derivater
AU649278B2 (en) Use of xanthines for the preparation of a medicament effective for inhibiting the replication of human retroviruses
ES2227522T3 (es) Compuestos aminoalquilo sustituidos.
IL106859A (en) Pentoxifilin metabolites and pharmaceutical preparations containing them for the treatment of VIH and similar diseases
WO1997038999A9 (en) Acridone-derived compounds useful as antineoplastic and antiretroviral agents
US6911460B2 (en) Antiviral agents and methods of treating viral infections
US20090149429A1 (en) Antiviral compounds
EP0422097B1 (en) Method of inhibiting the activity of human immunodeficiency virus (hiv) in vivo
EP0286825A2 (en) Use of 3'-fluro-3' deoxythymidine for the manufacture of a medicament for the treatment of virus infections
JP2005508283A (ja) 抗ｔｂ活性を有する新規ファーマコフォアとしてのピラノクマリン化合物
US9181294B2 (en) Nucleoside analogues for the treatment of a viral infection, and method for evaluating the sensitivity to said treatment
WO2002059123A2 (en) Benzoylalkylindolepyridinium compounds and pharmaceutical compositions comprising such compounds
US8513214B2 (en) C4′-substituted-2-deoxyadenosine analogs and methods of treating HIV
US5541212A (en) Use of cimetidine for the control of retrovirus infections
US5318979A (en) Method of inhibiting the activity of cryptosporidium parvum
US20020182151A1 (en) Benzoylalkylindolepyridinium componds and pharmaceutical compositions comprising such compounds
JP2006321817A (ja) レトロウイルス感染を阻害するための医薬組成物
US20240082235A1 (en) Method for treating or inhibiting cytomegalovirus infection using small molecules targeting protein phosphatase 1
Meleddu Synthesis of different series of small molecules targeting HIV-1 RT, Candida albicans, MAO and G-Quadruplex
EP2402357B1 (en) Analogs of 2',3'-dideoxy-3'-fluorothymidine 5'-monophosphate (FLTMP) for use in the treatment of infections caused by human HIV-1 strains
JPH07277969A (ja) フラボン誘導体を有効成分とする抗ｒｓウイルス剤
JPWO1993002671A1 (ja) レトロウイルス増殖阻害剤
KR20080071024A (ko) 피리미딘다이온 유도체를 포함하는 ｂ형 간염의 예방 및치료용 약학 조성물

Legal Events

Date Code Title Description
FC9A Application refused sect. 31(1)