ZA918801B - Use of xanthinges for the preparation of a medicament effective for inhibiting the replication of human retroviruses - Google Patents

Use of xanthinges for the preparation of a medicament effective for inhibiting the replication of human retroviruses

Info

Publication number
ZA918801B
ZA918801B ZA918801A ZA918801A ZA918801B ZA 918801 B ZA918801 B ZA 918801B ZA 918801 A ZA918801 A ZA 918801A ZA 918801 A ZA918801 A ZA 918801A ZA 918801 B ZA918801 B ZA 918801B
Authority
ZA
South Africa
Prior art keywords
group
chem
formula
carbon atoms
replication
Prior art date
Application number
ZA918801A
Other languages
English (en)
Inventor
Bruce J Dezube
J Dezube Bruce
Arthur B Pardee
B Pardee Arthur
Ruth M Ruprecht
M Ruprecht Ruth
William J Novick Jr
J Novick William Jr
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of ZA918801B publication Critical patent/ZA918801B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA918801A 1990-11-07 1991-11-06 Use of xanthinges for the preparation of a medicament effective for inhibiting the replication of human retroviruses ZA918801B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US61023090A 1990-11-07 1990-11-07

Publications (1)

Publication Number Publication Date
ZA918801B true ZA918801B (en) 1992-12-30

Family

ID=24444220

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA918801A ZA918801B (en) 1990-11-07 1991-11-06 Use of xanthinges for the preparation of a medicament effective for inhibiting the replication of human retroviruses

Country Status (16)

Country Link
EP (1) EP0484785B1 (xx)
JP (1) JPH054922A (xx)
KR (1) KR920009397A (xx)
AT (1) ATE138266T1 (xx)
AU (1) AU649278B2 (xx)
CA (1) CA2055041A1 (xx)
DE (1) DE69119700T2 (xx)
DK (1) DK0484785T3 (xx)
ES (1) ES2087205T3 (xx)
GR (1) GR3020017T3 (xx)
HU (1) HUT61468A (xx)
IE (1) IE913879A1 (xx)
IL (1) IL99966A0 (xx)
PT (1) PT99434A (xx)
TW (1) TW209169B (xx)
ZA (1) ZA918801B (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW288977B (xx) * 1992-02-22 1996-10-21 Hoechst Ag
ES2275400B1 (es) * 2005-04-20 2008-04-01 Universidad Autonoma De Madrid Uso de compuestos agonistas de la actividad tubulina desacetilasa de la proteina hdac6 en la elaboracion de composiciones farmaceuticas, dichas composiciones farmaceuticas y sus aplicaciones en el tratamiento de infecciones virales.
EP2265612B1 (en) 2008-02-29 2017-04-05 Concert Pharmaceuticals, Inc. Substituted xanthine derivatives
US8952016B2 (en) 2009-02-27 2015-02-10 Concert Pharmaceuticals, Inc. Substituted xanthine derivatives
US20110053961A1 (en) 2009-02-27 2011-03-03 Concert Pharmaceuticals, Inc. Substituted xanthine derivatives
WO2012031138A2 (en) 2010-09-01 2012-03-08 Concert Pharmaceuticals, Inc. Polymorphs of (s)-1-(4,4,6,6,6-pentadeutero-5-hydroxyhexyl)-3-7-dimethyl-1h-purine-2,6(3h,7h)dione
US20140296263A1 (en) 2011-07-19 2014-10-02 Concert Pharmaceuticals, Inc. Substituted xanthine derivatives
US9328113B2 (en) 2012-04-13 2016-05-03 Concert Pharmaceuticals, Inc. Substituted xanthine derivatives
WO2013159006A1 (en) 2012-04-20 2013-10-24 Concert Pharmaceuticals, Inc. Polymorphs of (s)-1-(4,4,6,6,6-pentadeutero-5-hydroxyhexyl)-3,7-dimethyl-1h-purine-2,6(3h,7h)-dione

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3737433A (en) * 1964-09-05 1973-06-05 Albert Ag Chem Werke Certain oxoalkyldimethylxanthines
CH608236A5 (xx) * 1974-01-22 1978-12-29 Wuelfing J A Fa
US4663317A (en) * 1984-04-18 1987-05-05 Board Of Regents, University Of Texas System Methods and compositions for treating viral infections
US4636507A (en) * 1984-04-30 1987-01-13 Hoechst-Roussel Pharmaceuticals Inc. Host defense mechanism enhancement
DE3525801A1 (de) * 1985-07-19 1987-01-22 Hoechst Ag Tertiaere hydroxyalkylxanthine, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung
GB8610136D0 (en) * 1986-04-25 1986-05-29 Wellcome Found Compounds
DE3725554A1 (de) * 1987-08-01 1989-02-09 Hoechst Ag Pharmazeutisches kombinationspraeparat sowie dessen herstellung und verwendung

Also Published As

Publication number Publication date
AU649278B2 (en) 1994-05-19
HUT61468A (en) 1993-01-28
EP0484785A2 (en) 1992-05-13
EP0484785A3 (en) 1992-12-16
JPH054922A (ja) 1993-01-14
IL99966A0 (en) 1992-08-18
DK0484785T3 (da) 1996-09-23
ATE138266T1 (de) 1996-06-15
GR3020017T3 (en) 1996-08-31
PT99434A (pt) 1992-09-30
EP0484785B1 (en) 1996-05-22
AU8699891A (en) 1992-05-14
CA2055041A1 (en) 1992-05-08
ES2087205T3 (es) 1996-07-16
TW209169B (xx) 1993-07-11
DE69119700T2 (de) 1996-11-07
HU913502D0 (en) 1992-01-28
DE69119700D1 (de) 1996-06-27
IE913879A1 (en) 1992-05-20
KR920009397A (ko) 1992-06-25

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