DK0484785T3 - Anvendelse af xanthiner til fremstilling af et lægemiddel, der er virksomt til inhibering af formeringen af humane retrovira - Google Patents

Anvendelse af xanthiner til fremstilling af et lægemiddel, der er virksomt til inhibering af formeringen af humane retrovira

Info

Publication number
DK0484785T3
DK0484785T3 DK91118347.3T DK91118347T DK0484785T3 DK 0484785 T3 DK0484785 T3 DK 0484785T3 DK 91118347 T DK91118347 T DK 91118347T DK 0484785 T3 DK0484785 T3 DK 0484785T3
Authority
DK
Denmark
Prior art keywords
group
chem
formula
carbon atoms
stands
Prior art date
Application number
DK91118347.3T
Other languages
Danish (da)
English (en)
Inventor
Bruce J Dezube
Arthur B Pardee
Ruth M Ruprecht
William J Novick Jr
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Application granted granted Critical
Publication of DK0484785T3 publication Critical patent/DK0484785T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK91118347.3T 1990-11-07 1991-10-28 Anvendelse af xanthiner til fremstilling af et lægemiddel, der er virksomt til inhibering af formeringen af humane retrovira DK0484785T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US61023090A 1990-11-07 1990-11-07

Publications (1)

Publication Number Publication Date
DK0484785T3 true DK0484785T3 (da) 1996-09-23

Family

ID=24444220

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91118347.3T DK0484785T3 (da) 1990-11-07 1991-10-28 Anvendelse af xanthiner til fremstilling af et lægemiddel, der er virksomt til inhibering af formeringen af humane retrovira

Country Status (16)

Country Link
EP (1) EP0484785B1 (xx)
JP (1) JPH054922A (xx)
KR (1) KR920009397A (xx)
AT (1) ATE138266T1 (xx)
AU (1) AU649278B2 (xx)
CA (1) CA2055041A1 (xx)
DE (1) DE69119700T2 (xx)
DK (1) DK0484785T3 (xx)
ES (1) ES2087205T3 (xx)
GR (1) GR3020017T3 (xx)
HU (1) HUT61468A (xx)
IE (1) IE913879A1 (xx)
IL (1) IL99966A0 (xx)
PT (1) PT99434A (xx)
TW (1) TW209169B (xx)
ZA (1) ZA918801B (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0557876B1 (de) * 1992-02-22 1996-12-11 Hoechst Aktiengesellschaft Verwendung von Xanthinderivaten zur Behandlung von Muskelschädigungen nach vollständiger Unterbrechung der Blutzirkulation
ES2275400B1 (es) * 2005-04-20 2008-04-01 Universidad Autonoma De Madrid Uso de compuestos agonistas de la actividad tubulina desacetilasa de la proteina hdac6 en la elaboracion de composiciones farmaceuticas, dichas composiciones farmaceuticas y sus aplicaciones en el tratamiento de infecciones virales.
CA2716788C (en) 2008-02-29 2016-08-16 Concert Pharmaceuticals, Inc. Deuterium-substituted xanthine derivatives
US20110053961A1 (en) 2009-02-27 2011-03-03 Concert Pharmaceuticals, Inc. Substituted xanthine derivatives
IN2012DN01642A (xx) 2009-09-02 2015-06-05 Concert Pharmaceuticals Inc
US20130324564A1 (en) 2010-09-01 2013-12-05 Concert Pharmaceuticals, Inc. Polymorphs of (s)-1-(4,4,6,6,6-pentadeutero-5-hydroxyhexyl)-3-7-dimethyl-1h-purine-2,6(3h,7h)-dione
WO2013013052A1 (en) 2011-07-19 2013-01-24 Concert Pharmaceuticals, Inc. Substituted xanthine derivatives
JP2015512947A (ja) 2012-04-13 2015-04-30 コンサート ファーマシューティカルズ インコーポレイテッド 置換キサンチン誘導体
WO2013159006A1 (en) 2012-04-20 2013-10-24 Concert Pharmaceuticals, Inc. Polymorphs of (s)-1-(4,4,6,6,6-pentadeutero-5-hydroxyhexyl)-3,7-dimethyl-1h-purine-2,6(3h,7h)-dione

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3737433A (en) * 1964-09-05 1973-06-05 Albert Ag Chem Werke Certain oxoalkyldimethylxanthines
CH608236A5 (xx) * 1974-01-22 1978-12-29 Wuelfing J A Fa
US4663317A (en) * 1984-04-18 1987-05-05 Board Of Regents, University Of Texas System Methods and compositions for treating viral infections
US4636507A (en) * 1984-04-30 1987-01-13 Hoechst-Roussel Pharmaceuticals Inc. Host defense mechanism enhancement
DE3525801A1 (de) * 1985-07-19 1987-01-22 Hoechst Ag Tertiaere hydroxyalkylxanthine, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung
GB8610136D0 (en) * 1986-04-25 1986-05-29 Wellcome Found Compounds
DE3725554A1 (de) * 1987-08-01 1989-02-09 Hoechst Ag Pharmazeutisches kombinationspraeparat sowie dessen herstellung und verwendung

Also Published As

Publication number Publication date
DE69119700D1 (de) 1996-06-27
TW209169B (xx) 1993-07-11
EP0484785B1 (en) 1996-05-22
DE69119700T2 (de) 1996-11-07
ES2087205T3 (es) 1996-07-16
ATE138266T1 (de) 1996-06-15
HU913502D0 (en) 1992-01-28
HUT61468A (en) 1993-01-28
PT99434A (pt) 1992-09-30
IL99966A0 (en) 1992-08-18
CA2055041A1 (en) 1992-05-08
IE913879A1 (en) 1992-05-20
ZA918801B (en) 1992-12-30
AU8699891A (en) 1992-05-14
AU649278B2 (en) 1994-05-19
EP0484785A3 (en) 1992-12-16
KR920009397A (ko) 1992-06-25
EP0484785A2 (en) 1992-05-13
GR3020017T3 (en) 1996-08-31
JPH054922A (ja) 1993-01-14

Similar Documents

Publication Publication Date Title
DK0483634T3 (da) Aminoglycosidsammensætning med væsentlig nedsat nefrotoksicitet fremkaldt af aminoglycosidet
LU88749I2 (fr) TACRINE et ses dérivés pharmaceutiquement acceptables (COGNEX)
ES8300716A1 (es) Procedimiento para preparar derivados de 2-amino-4-hidroxi- quinazolina
ES468119A1 (es) Un procedimiento para la preparacion de triazinas
NO308739B1 (no) Imidazolderivater samt medisinsk sammensetning og anti-HIV- sammensetning omfattende samme
IL86040A (en) Acid stable purine dideoxynu- cleosides, their preparation and pharmaceutical compositions containing them
IL103944A (en) Piperazine derivatives, their preparation and pharmaceutical compositions containing them
DK0484785T3 (da) Anvendelse af xanthiner til fremstilling af et lægemiddel, der er virksomt til inhibering af formeringen af humane retrovira
KR900700463A (ko) 6-치환 비환식 피리미딘 뉴클레오시드 유도체 및 그 유도체를 유효성분으로 하는 항 비루스재
DE3176053D1 (en) Plant protecting agents for use during weed control, 2-(dichloromethyl)-3-phenyl-1,3-oxazolidine and 2-(dichloromethyl)-3-allyl-1,3-oxazolidine, and method for the preparation of the compounds comprised in said agents as antidotes, or of the latter mentioned compounds
DK0557876T3 (da) Anvendelse af xanthinderivater til behandling af muskelskader efter fuldstændig afbrydelse af blodcirkulationen
SE8100946L (sv) Nya indanderivat, sett att framstella dem, anvendning derav som farmaceutika och farmaceutiska kompositioner som innehaller dess derivat
ES2055371T3 (es) Derivados de fenotiazina, su preparacion y las composiciones farmaceuticas que les contienen.
KR910004621A (ko) 신규 화합물
DK0653207T3 (da) Sammensætning til hæmning af AIDS-virus-infektion
TH17157A (th) อนุพันธ์ไพริมิดีนอะไซโคลนิวคลีโอไซด์