IE52378B1 - A new process for the preparation of the d-2-(6-methoxy-2-naphthyl)-propionic acid - Google Patents

A new process for the preparation of the d-2-(6-methoxy-2-naphthyl)-propionic acid

Info

Publication number
IE52378B1
IE52378B1 IE770/82A IE77082A IE52378B1 IE 52378 B1 IE52378 B1 IE 52378B1 IE 770/82 A IE770/82 A IE 770/82A IE 77082 A IE77082 A IE 77082A IE 52378 B1 IE52378 B1 IE 52378B1
Authority
IE
Ireland
Prior art keywords
naphthyl
methoxy
process according
mixture
propionic acid
Prior art date
Application number
IE770/82A
Other languages
English (en)
Other versions
IE820770L (en
Original Assignee
Alfa Chem Ital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11106122&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IE52378(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alfa Chem Ital filed Critical Alfa Chem Ital
Publication of IE820770L publication Critical patent/IE820770L/xx
Publication of IE52378B1 publication Critical patent/IE52378B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/377—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
    • C07C45/58—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in three-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IE770/82A 1981-04-01 1982-03-31 A new process for the preparation of the d-2-(6-methoxy-2-naphthyl)-propionic acid IE52378B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT03385/81A IT1168387B (it) 1981-04-01 1981-04-01 Procedimento per la preparazione dell'acido 2-(6-metossi-2-naftil)-propionico

Publications (2)

Publication Number Publication Date
IE820770L IE820770L (en) 1982-10-01
IE52378B1 true IE52378B1 (en) 1987-09-30

Family

ID=11106122

Family Applications (1)

Application Number Title Priority Date Filing Date
IE770/82A IE52378B1 (en) 1981-04-01 1982-03-31 A new process for the preparation of the d-2-(6-methoxy-2-naphthyl)-propionic acid

Country Status (26)

Country Link
US (1) US4423244A (cg-RX-API-DMAC7.html)
JP (1) JPS57176925A (cg-RX-API-DMAC7.html)
KR (1) KR860001547B1 (cg-RX-API-DMAC7.html)
AR (1) AR230614A1 (cg-RX-API-DMAC7.html)
AT (1) AT390253B (cg-RX-API-DMAC7.html)
BE (1) BE892689A (cg-RX-API-DMAC7.html)
CA (1) CA1190939A (cg-RX-API-DMAC7.html)
CH (1) CH651289A5 (cg-RX-API-DMAC7.html)
DE (1) DE3212170A1 (cg-RX-API-DMAC7.html)
DK (2) DK157076C (cg-RX-API-DMAC7.html)
ES (1) ES8302622A1 (cg-RX-API-DMAC7.html)
FI (1) FI78455C (cg-RX-API-DMAC7.html)
FR (1) FR2504918B1 (cg-RX-API-DMAC7.html)
GB (1) GB2098981B (cg-RX-API-DMAC7.html)
GR (1) GR76062B (cg-RX-API-DMAC7.html)
HU (1) HU186852B (cg-RX-API-DMAC7.html)
IE (1) IE52378B1 (cg-RX-API-DMAC7.html)
IL (1) IL65298A (cg-RX-API-DMAC7.html)
IT (1) IT1168387B (cg-RX-API-DMAC7.html)
LU (1) LU84044A1 (cg-RX-API-DMAC7.html)
NL (1) NL8201307A (cg-RX-API-DMAC7.html)
NO (1) NO157733B (cg-RX-API-DMAC7.html)
PT (1) PT74677B (cg-RX-API-DMAC7.html)
SE (2) SE453492C (cg-RX-API-DMAC7.html)
YU (1) YU42606B (cg-RX-API-DMAC7.html)
ZA (1) ZA822145B (cg-RX-API-DMAC7.html)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI831820L (fi) * 1982-05-27 1983-11-28 Syntex Pharma Int Foerfarande foer framstaellning av d-2-(6-metoxi-2-naftyl)-propionsyra och dess farmaceutiskt godtagbara salter samt av nya mellanprodukter anvaenda vid deras framstaellning
ZA833838B (en) * 1982-05-27 1985-01-30 Syntex Pharma Int Process for the preparation of(d)-2-(6-methoxy-2-naphthyl)propionic acid and pharmaceutically acceptable salts thereof and new intermediates therefor
US4723033A (en) * 1982-11-24 1988-02-02 Syntex Pharmaceuticals International Ltd. Manufacture of optically active α-arylalkanoic acids and precursors thereof
IT1174084B (it) * 1984-05-10 1987-07-01 Blaschim Spa Procentimento per preparare il naproxen
US4814497A (en) * 1986-05-12 1989-03-21 Ethyl Corporation Dehalogenation process
IT1238008B (it) * 1990-02-08 1993-06-21 Alfa Wassermann Spa Procedimento per la debromurazione di 2-sostituiti-5-bromo- 6-metossinaftaleni
FR2686877B1 (fr) * 1992-01-31 1995-03-24 Hoechst France Procede de preparation de l'acide orthohydroxyphenylacetique.
JPH0646907U (ja) * 1992-12-10 1994-06-28 リョービ株式会社 すべり勾配面加工用治具
US5574183A (en) * 1995-01-24 1996-11-12 Albemarle Corporation Preparation of optically active aliphatic carboxylic acids
US6436990B1 (en) 1999-10-27 2002-08-20 Nobex Corporation 6-methoxy-2-naphthylacetic acid prodrugs
US6552078B2 (en) 1999-10-27 2003-04-22 Nobex Corp 6-methoxy-2-naphthylacetic acid prodrugs
TWI262791B (en) 1999-10-27 2006-10-01 Nobex Corp 6-methoxy-2-naphthylacetic acid prodrugs

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3904682A (en) * 1967-01-13 1975-09-09 Syntex Corp 2-(6{40 -Methoxy-2{40 -naphthyl)acetic acid
US3637767A (en) * 1968-07-30 1972-01-25 Syntex Corp 2-(6'-methoxynaphth-2'-yl)propylene oxide and 5'-halo derivatives
US3686183A (en) * 1969-03-24 1972-08-22 Syntex Corp Preparation of optical isomers of arylalkylacetic acids
CA936171A (en) * 1970-09-09 1973-10-30 Syntex Corporation Process for preparing 2-(6-methoxy-2-naphthyl) propionic acid and 2-(6-methoxy-2-naphthyl)-1-propanol
CH641432A5 (de) * 1978-07-19 1984-02-29 Syntex Pharma Int Verfahren zur aufspaltung von racemischer 6-methoxy-alpha-methyl-2-naphthalinessigsaeure in die optischen antipoden.
PH15674A (en) * 1979-07-06 1983-03-11 Syntex Corp Process for the resolution of d,1 2-(6-methoxy-2-naphthyl)propionic acid

Also Published As

Publication number Publication date
IL65298A0 (en) 1982-05-31
NL8201307A (nl) 1982-11-01
SE453492B (sv) 1988-02-08
IT8103385A0 (it) 1981-04-01
LU84044A1 (fr) 1983-02-22
GB2098981A (en) 1982-12-01
FR2504918B1 (fr) 1985-06-14
FI821121L (fi) 1982-10-02
DK256589A (da) 1989-05-26
BE892689A (fr) 1982-09-30
ES510931A0 (es) 1983-02-01
HU186852B (en) 1985-10-28
SE8501744L (sv) 1985-04-09
GB2098981B (en) 1984-10-24
ES8302622A1 (es) 1983-02-01
NO157733B (no) 1988-02-01
SE466199B (sv) 1992-01-13
NO821088L (no) 1982-10-04
US4423244A (en) 1983-12-27
IT1168387B (it) 1987-05-20
FR2504918A1 (fr) 1982-11-05
FI78455C (fi) 1989-08-10
YU72082A (en) 1985-03-20
AR230614A1 (es) 1984-05-31
JPH0231704B2 (cg-RX-API-DMAC7.html) 1990-07-16
CH651289A5 (de) 1985-09-13
IL65298A (en) 1985-02-28
ATA127082A (de) 1989-09-15
DE3212170A1 (de) 1982-10-21
KR860001547B1 (ko) 1986-10-04
DK157076C (da) 1990-04-09
KR830008973A (ko) 1983-12-16
DK256589D0 (da) 1989-05-26
FI78455B (fi) 1989-04-28
GR76062B (cg-RX-API-DMAC7.html) 1984-08-03
DK157076B (da) 1989-11-06
AT390253B (de) 1990-04-10
SE8501744D0 (sv) 1985-04-09
DK147482A (da) 1982-10-02
JPS57176925A (en) 1982-10-30
US4423244B1 (cg-RX-API-DMAC7.html) 1987-07-28
SE8202050L (sv) 1982-10-02
SE453492C (sv) 1994-10-03
ZA822145B (en) 1983-02-23
PT74677B (en) 1983-10-31
DE3212170C2 (cg-RX-API-DMAC7.html) 1989-03-02
FI821121A0 (fi) 1982-03-31
IE820770L (en) 1982-10-01
CA1190939A (en) 1985-07-23
PT74677A (en) 1982-04-01
YU42606B (en) 1988-10-31

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