IE45470B1 - Thiophene derivatives - Google Patents

Thiophene derivatives

Info

Publication number
IE45470B1
IE45470B1 IE1751/77A IE175177A IE45470B1 IE 45470 B1 IE45470 B1 IE 45470B1 IE 1751/77 A IE1751/77 A IE 1751/77A IE 175177 A IE175177 A IE 175177A IE 45470 B1 IE45470 B1 IE 45470B1
Authority
IE
Ireland
Prior art keywords
group
amino
formula
compound
hydrochloride
Prior art date
Application number
IE1751/77A
Other languages
English (en)
Other versions
IE45470L (en
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IE45470L publication Critical patent/IE45470L/xx
Publication of IE45470B1 publication Critical patent/IE45470B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IE1751/77A 1976-08-23 1977-08-22 Thiophene derivatives IE45470B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US71685376A 1976-08-23 1976-08-23
US71685476A 1976-08-23 1976-08-23
US82052177A 1977-08-01 1977-08-01

Publications (2)

Publication Number Publication Date
IE45470L IE45470L (en) 1978-02-23
IE45470B1 true IE45470B1 (en) 1982-09-08

Family

ID=27418961

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1751/77A IE45470B1 (en) 1976-08-23 1977-08-22 Thiophene derivatives

Country Status (21)

Country Link
JP (1) JPS5340755A (enrdf_load_stackoverflow)
AR (1) AR222453A1 (enrdf_load_stackoverflow)
AT (1) AT359486B (enrdf_load_stackoverflow)
AU (1) AU509956B2 (enrdf_load_stackoverflow)
BE (1) BE858012A (enrdf_load_stackoverflow)
CH (1) CH628628A5 (enrdf_load_stackoverflow)
DE (1) DE2737738C2 (enrdf_load_stackoverflow)
DK (1) DK150484C (enrdf_load_stackoverflow)
ES (1) ES461796A1 (enrdf_load_stackoverflow)
FI (1) FI66859C (enrdf_load_stackoverflow)
FR (1) FR2365566A1 (enrdf_load_stackoverflow)
GB (1) GB1587084A (enrdf_load_stackoverflow)
HU (1) HU179484B (enrdf_load_stackoverflow)
IE (1) IE45470B1 (enrdf_load_stackoverflow)
IL (1) IL52792A (enrdf_load_stackoverflow)
IT (1) IT1143757B (enrdf_load_stackoverflow)
LU (1) LU78003A1 (enrdf_load_stackoverflow)
MC (1) MC1156A1 (enrdf_load_stackoverflow)
NL (1) NL7709246A (enrdf_load_stackoverflow)
NO (1) NO148673C (enrdf_load_stackoverflow)
NZ (1) NZ184981A (enrdf_load_stackoverflow)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6232765Y2 (enrdf_load_stackoverflow) * 1981-02-28 1987-08-21
US5811447A (en) 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5847007A (en) 1993-05-13 1998-12-08 Neorx Corporation Prevention and treatment of pathologies associated with abnormally proliferative smooth muscle cells
US6251920B1 (en) 1993-05-13 2001-06-26 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
AU6959898A (en) * 1997-04-11 1998-11-11 David J. Grainger Compounds and therapies for the prevention of vascular and non-vascular pathol ogies
US6613083B2 (en) 2001-05-02 2003-09-02 Eckhard Alt Stent device and method
DE102004063191A1 (de) 2004-12-29 2006-07-13 Bayer Cropscience Ag Verfahren zur Herstellung von substituierten 2-Alkoxycarbonyl-3-aminothiophenen
CN103435593B (zh) 2008-02-29 2015-01-28 日产化学工业株式会社 噻吩化合物及其中间体的制造方法
AR130733A1 (es) 2022-10-14 2025-01-15 Adama Agan Ltd Proceso para la preparación de aminotiofeno sustituido

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2502421A (en) * 1944-08-28 1950-04-04 Parke Davis & Co Tetrahydrothiophenes
US2443598A (en) * 1944-12-23 1948-06-22 Parke Davis & Co 3-amino-4-carbethoxy-2-alkyl derivatives of thiophene
US2502424A (en) * 1944-12-23 1950-04-04 Parke Davis & Co 3-acylamino-4-carboalkoxy-2-omega-ralkylthiophenes
US2502423A (en) * 1944-12-23 1950-04-04 Parke Davis & Co 4-carbalkoxy-3-keto-2-substituted tetrahydrothiophene oximes

Also Published As

Publication number Publication date
IE45470L (en) 1978-02-23
MC1156A1 (fr) 1978-04-17
NL7709246A (nl) 1978-02-27
NO148673B (no) 1983-08-15
BE858012A (fr) 1978-02-22
DK150484B (da) 1987-03-09
DK372177A (da) 1978-02-24
LU78003A1 (enrdf_load_stackoverflow) 1978-09-14
CH628628A5 (en) 1982-03-15
FR2365566B1 (enrdf_load_stackoverflow) 1980-12-26
GB1587084A (en) 1981-03-25
IL52792A0 (en) 1977-10-31
IT1143757B (it) 1986-10-22
NO148673C (no) 1983-11-23
AU509956B2 (en) 1980-06-05
FR2365566A1 (fr) 1978-04-21
FI66859C (fi) 1984-12-10
AT359486B (de) 1980-11-10
DE2737738A1 (de) 1978-03-09
DK150484C (da) 1987-10-05
ES461796A1 (es) 1978-12-16
HU179484B (en) 1982-10-28
ATA607477A (de) 1980-04-15
AR222453A1 (es) 1981-05-29
JPS6121235B2 (enrdf_load_stackoverflow) 1986-05-26
FI66859B (fi) 1984-08-31
DE2737738C2 (de) 1987-01-29
IL52792A (en) 1981-06-29
NZ184981A (en) 1980-08-26
JPS5340755A (en) 1978-04-13
AU2809277A (en) 1979-03-01
NO772917L (no) 1978-02-24
FI772494A7 (fi) 1978-02-24

Similar Documents

Publication Publication Date Title
KR910000414B1 (ko) 비사이클릭 화합물의 n-이미다졸릴 유도체의 제조방법
US4226878A (en) Imidazole derivative
US4070539A (en) [1-Oxo-2-halo(or hydrogen) indanyloxy]-alkanoic acid
US3784697A (en) Pharmaceutical composition containing phenoxyalkane-carboxylic acids,salts and esters thereof
US4337263A (en) 1-Aryl-4-γ-arylsulphonyl-3-aminopropoxy-1H-pyrazoles and their use as hypolipemiant and hypocholesterolemiant agents
US4892963A (en) N-phenyl amide compounds
NO743014L (enrdf_load_stackoverflow)
IE45470B1 (en) Thiophene derivatives
EA004931B1 (ru) 3, 4, 5-тризамещенные арилнитроны и содержащие их фармацевтические композиции
NO168299B (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive alkansulfonanilid-derivater
US4375479A (en) Indanyl derivatives and use
US4234742A (en) Bis-(aryloxycarboxylic acid) compounds
SU1199197A3 (ru) Способ получени производных фенилалкановой кислоты
JPH0261950B2 (enrdf_load_stackoverflow)
US5523310A (en) 1,2,3-triazole derivatives
CH407088A (fr) Procédé de préparation de dérivés des acides 4-halo-3-sulfamoyl-benzoïques
SU900808A3 (ru) Способ получени аминопропанолпроизводных 6-окси-2,3,4,5-тетрагидро-1н-1-бензазепин-2-она или их солей
US4154743A (en) 3-Oxobenzofuranyl-2-idenyl, haloacetic acids
JPH04360881A (ja) 新規のベンゾセレナゾリノン化合物、これらを調製するプロセスおよびそれらを含む薬剤組成物
US4389416A (en) Diphenyl ether, diphenyl thioether and diphenyl methane phenol mannich bases
US3873539A (en) Substituted-4-aminoacetyl alkanoylphenones
BE779775A (fr) Derives de l'uree, procede pour les preparer et leurs applications
EP0142754A2 (en) 2-Substituted-benzoic acid imidazoles, process for preparing them and pharmaceutical compositions containing them
US3539628A (en) Derivatives of acetic acid
CA1292239C (en) Cycloalkyl-substituted 4-aminophenyl halo derivatives and process for their preparation