ID28470A - Formulasi-formulasi untuk perlindungan terhadap konjugasi polietilen glikol-interferon alfa - Google Patents

Formulasi-formulasi untuk perlindungan terhadap konjugasi polietilen glikol-interferon alfa

Info

Publication number
ID28470A
ID28470A IDW20001920A ID20001920A ID28470A ID 28470 A ID28470 A ID 28470A ID W20001920 A IDW20001920 A ID W20001920A ID 20001920 A ID20001920 A ID 20001920A ID 28470 A ID28470 A ID 28470A
Authority
ID
Indonesia
Prior art keywords
conjugation
formulations
glycol
polyethylene
protection
Prior art date
Application number
IDW20001920A
Other languages
English (en)
Indonesian (id)
Inventor
Douglas F Kline
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21957085&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ID28470(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp filed Critical Schering Corp
Publication of ID28470A publication Critical patent/ID28470A/id

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • A61K38/212IFN-alpha
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
IDW20001920A 1998-03-26 1999-03-24 Formulasi-formulasi untuk perlindungan terhadap konjugasi polietilen glikol-interferon alfa ID28470A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4890798A 1998-03-26 1998-03-26

Publications (1)

Publication Number Publication Date
ID28470A true ID28470A (id) 2001-05-24

Family

ID=21957085

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20001920A ID28470A (id) 1998-03-26 1999-03-24 Formulasi-formulasi untuk perlindungan terhadap konjugasi polietilen glikol-interferon alfa

Country Status (26)

Country Link
EP (1) EP1066059B1 (pt)
JP (3) JP3643034B2 (pt)
KR (1) KR100420642B1 (pt)
CN (1) CN1191863C (pt)
AR (1) AR014772A1 (pt)
AT (1) ATE297761T1 (pt)
AU (1) AU754002B2 (pt)
BR (1) BR9909087A (pt)
CA (1) CA2324467C (pt)
CO (1) CO5080738A1 (pt)
CZ (1) CZ302005B6 (pt)
DE (1) DE69925820T2 (pt)
ES (1) ES2241272T3 (pt)
HK (1) HK1029754A1 (pt)
HU (1) HU228877B1 (pt)
ID (1) ID28470A (pt)
IL (2) IL138221A0 (pt)
MY (1) MY119227A (pt)
NO (1) NO329916B1 (pt)
NZ (1) NZ506631A (pt)
PE (1) PE20000338A1 (pt)
PL (1) PL193286B1 (pt)
PT (1) PT1066059E (pt)
SK (1) SK285284B6 (pt)
TW (2) TWI250024B (pt)
WO (1) WO1999048535A1 (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3643034B2 (ja) * 1998-03-26 2005-04-27 シェーリング コーポレイション PEG−インターフェロンα結合体の保護のための処方物
DE60041291D1 (de) * 1999-04-08 2009-02-12 Schering Corp Behandlung von Nierenzellen-Karzinom
US6605273B2 (en) 1999-04-08 2003-08-12 Schering Corporation Renal cell carcinoma treatment
US6362162B1 (en) 1999-04-08 2002-03-26 Schering Corporation CML Therapy
US6923966B2 (en) 1999-04-08 2005-08-02 Schering Corporation Melanoma therapy
MXPA02007172A (es) * 2000-01-24 2002-12-13 Schering Corp Combinacion de temozolomida y alfa interferon pegilado para tratamiento de cancer.
EP1908477A3 (en) * 2000-01-24 2008-06-11 Schering Corporation Combination of temozolomide and pegylated interferon-alpha for treating cancer
KR100353392B1 (ko) * 2000-03-13 2002-09-18 선바이오(주) 높은 생체 활성도를 갖는 생체 활성 단백질과 peg의결합체 제조방법
WO2001074400A1 (fr) 2000-04-03 2001-10-11 Santen Pharmaceutical Co., Ltd. Transporteurs et systeme de distribution de medicament les utilisant
CN101172104B (zh) 2002-02-22 2013-04-03 默沙东公司 抗肿瘤剂,特别是替莫唑胺的药物制剂,其制备方法和用途
AU2008201682B2 (en) * 2004-02-02 2011-02-24 Ambrx, Inc. Modified human interferon polypeptides and their uses
JP4971160B2 (ja) * 2004-08-12 2012-07-11 シェーリング コーポレイション 安定するpeg化インターフェロン処方物
PT2234645E (pt) 2007-12-20 2012-05-21 Merck Serono Sa Formulações de peg-interferão-beta
KR101303388B1 (ko) * 2010-10-26 2013-09-03 한미사이언스 주식회사 지속형 인터페론 알파 결합체의 액상 제제
JP2015535238A (ja) * 2012-10-26 2015-12-10 ルピン・リミテッドLupin Limited ペグインターフェロンα−2bの安定な医薬組成物
KR101736870B1 (ko) 2014-08-20 2017-05-18 한국코러스 주식회사 인터페론 접합체를 포함하는 복합체 및 이의 제조방법
EP4019007A1 (en) 2016-06-01 2022-06-29 Servier IP UK Limited Formulations of polyalkylene oxide-asparaginase and methods of making and using the same
CN112358541B (zh) * 2020-11-25 2022-04-01 广州迪澳医疗科技有限公司 一种重组人γ-干扰素的冻干保护剂

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2024046A1 (en) * 1989-09-28 1991-03-29 Alberto Ferro Stabilized leukocyte-interferons
US5382657A (en) * 1992-08-26 1995-01-17 Hoffmann-La Roche Inc. Peg-interferon conjugates
WO1995013090A1 (en) * 1993-11-10 1995-05-18 Enzon, Inc. Improved interferon polymer conjugates
US5766582A (en) * 1994-10-11 1998-06-16 Schering Corporation Stable, aqueous alfa interferon solution formulations
US5738846A (en) * 1994-11-10 1998-04-14 Enzon, Inc. Interferon polymer conjugates and process for preparing the same
JP2000510813A (ja) * 1995-02-06 2000-08-22 ジェネテイックス・インスティテュート・インコーポレイテッド Il−12用処方
TW426523B (en) * 1995-04-06 2001-03-21 Hoffmann La Roche Interferon solution
CN102416176A (zh) * 1995-07-27 2012-04-18 基因技术股份有限公司 稳定等渗的冻干蛋白质制剂
CA2329474C (en) * 1995-11-02 2002-02-26 Schering Corporation Continuous low-dose cytokine infusion therapy
US5908621A (en) * 1995-11-02 1999-06-01 Schering Corporation Polyethylene glycol modified interferon therapy
TW517067B (en) * 1996-05-31 2003-01-11 Hoffmann La Roche Interferon conjugates
JP3643034B2 (ja) * 1998-03-26 2005-04-27 シェーリング コーポレイション PEG−インターフェロンα結合体の保護のための処方物

Also Published As

Publication number Publication date
IL138221A (en) 2007-12-03
AU754002B2 (en) 2002-10-31
HUP0101749A2 (hu) 2001-11-28
PL345568A1 (en) 2001-12-17
MY119227A (en) 2005-04-30
EP1066059B1 (en) 2005-06-15
AU3181299A (en) 1999-10-18
KR100420642B1 (ko) 2004-03-02
CN1295484A (zh) 2001-05-16
CZ20003315A3 (cs) 2001-04-11
AR014772A1 (es) 2001-03-28
CA2324467A1 (en) 1999-09-30
JP2002507583A (ja) 2002-03-12
JP2003221345A (ja) 2003-08-05
KR20010034654A (ko) 2001-04-25
DE69925820D1 (de) 2005-07-21
NO20004785D0 (no) 2000-09-25
JP4580744B2 (ja) 2010-11-17
SK14262000A3 (sk) 2001-04-09
TWI250024B (en) 2006-03-01
HU228877B1 (en) 2013-06-28
CO5080738A1 (es) 2001-09-25
CZ302005B6 (cs) 2010-09-01
PL193286B1 (pl) 2007-01-31
IL138221A0 (en) 2001-10-31
SK285284B6 (sk) 2006-10-05
CA2324467C (en) 2002-11-05
NZ506631A (en) 2003-03-28
PT1066059E (pt) 2005-10-31
TW200536557A (en) 2005-11-16
CN1191863C (zh) 2005-03-09
PE20000338A1 (es) 2000-05-16
EP1066059A1 (en) 2001-01-10
BR9909087A (pt) 2000-12-05
HK1029754A1 (en) 2001-04-12
DE69925820T2 (de) 2006-05-18
NO329916B1 (no) 2011-01-24
JP2005104985A (ja) 2005-04-21
JP3643034B2 (ja) 2005-04-27
ATE297761T1 (de) 2005-07-15
ES2241272T3 (es) 2005-10-16
TWI243057B (en) 2005-11-11
NO20004785L (no) 2000-09-25
HUP0101749A3 (en) 2001-12-28
WO1999048535A1 (en) 1999-09-30

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