ID27845A - Turunan tetrahidrokuilina sebagai antagonis glisilina - Google Patents

Turunan tetrahidrokuilina sebagai antagonis glisilina

Info

Publication number
ID27845A
ID27845A IDW20010061A ID20010061A ID27845A ID 27845 A ID27845 A ID 27845A ID W20010061 A IDW20010061 A ID W20010061A ID 20010061 A ID20010061 A ID 20010061A ID 27845 A ID27845 A ID 27845A
Authority
ID
Indonesia
Prior art keywords
tetrahidrokuilina
glisilina
antagonists
decreased
tetrahidrokuilina decreased
Prior art date
Application number
IDW20010061A
Other languages
English (en)
Indonesian (id)
Inventor
Romano Di Fabio
Original Assignee
Glaxo Wellcome Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9812408.4A external-priority patent/GB9812408D0/en
Priority claimed from GBGB9812410.0A external-priority patent/GB9812410D0/en
Application filed by Glaxo Wellcome Spa filed Critical Glaxo Wellcome Spa
Publication of ID27845A publication Critical patent/ID27845A/id

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IDW20010061A 1998-06-10 1999-06-08 Turunan tetrahidrokuilina sebagai antagonis glisilina ID27845A (id)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9812408.4A GB9812408D0 (en) 1998-06-10 1998-06-10 Heterocyclic compounds
GBGB9812410.0A GB9812410D0 (en) 1998-06-10 1998-06-10 Heterocyclic derivatives

Publications (1)

Publication Number Publication Date
ID27845A true ID27845A (id) 2001-04-26

Family

ID=26313826

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20010061A ID27845A (id) 1998-06-10 1999-06-08 Turunan tetrahidrokuilina sebagai antagonis glisilina

Country Status (34)

Country Link
US (3) US6362199B1 (bg)
EP (1) EP1086093B1 (bg)
JP (1) JP2002517492A (bg)
KR (1) KR100586762B1 (bg)
CN (1) CN1173970C (bg)
AP (1) AP2000002008A0 (bg)
AR (1) AR018632A1 (bg)
AT (1) ATE301650T1 (bg)
AU (1) AU753867B2 (bg)
BG (1) BG105123A (bg)
BR (1) BR9911145A (bg)
CA (1) CA2334727C (bg)
CO (1) CO5080785A1 (bg)
CZ (1) CZ293605B6 (bg)
DE (1) DE69926632T2 (bg)
DK (1) DK1086093T3 (bg)
EA (1) EA003276B1 (bg)
EE (1) EE200000733A (bg)
ES (1) ES2249010T3 (bg)
HK (1) HK1034079A1 (bg)
HR (1) HRP20000845A2 (bg)
HU (1) HUP0102767A3 (bg)
ID (1) ID27845A (bg)
IL (2) IL140062A0 (bg)
IS (1) IS5746A (bg)
MY (1) MY125037A (bg)
NO (1) NO321904B1 (bg)
NZ (1) NZ508638A (bg)
OA (1) OA11564A (bg)
PE (1) PE20000724A1 (bg)
PL (1) PL197160B1 (bg)
TR (1) TR200003652T2 (bg)
TW (1) TWI229079B (bg)
WO (1) WO1999064411A1 (bg)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY125037A (en) 1998-06-10 2006-07-31 Glaxo Wellcome Spa 1,2,3,4 tetrahydroquinoline derivatives
US6455734B1 (en) 2000-08-09 2002-09-24 Magnesium Diagnostics, Inc. Antagonists of the magnesium binding defect as therapeutic agents and methods for treatment of abnormal physiological states
GB9929037D0 (en) * 1999-12-08 2000-02-02 Glaxo Wellcome Spa Heterocyclic derivatives
DE10000311A1 (de) 2000-01-05 2001-07-12 Gruenenthal Gmbh Aminomethyl-Phonyl-Cyclohexanonderivate
DE10005302A1 (de) * 2000-02-07 2002-01-17 Gruenenthal Gmbh Substituierte 1,2,3,4-Tetrahydrochinolin-2-carbonsäurederivate
DE10137487A1 (de) 2001-08-03 2003-03-27 Gruenenthal Gmbh Substituierte 5,6,6a,11b-Tetrahydro-7-oxa-6-aza- benzo[c]fluoren-6-carbonsäurederivate
DE10137488A1 (de) * 2001-08-03 2003-02-20 Gruenenthal Gmbh Salze substituierter 1,2,3,4-Tetrahydrochinolin-2-carbonsäurederivate
US20090181966A1 (en) * 2002-10-04 2009-07-16 Millennium Pharmaceuticals, Inc. PGD2 receptor antagonists for the treatment of inflammatory diseases
US7504508B2 (en) * 2002-10-04 2009-03-17 Millennium Pharmaceuticals, Inc. PGD2 receptor antagonists for the treatment of inflammatory diseases
EP1556047A4 (en) * 2002-10-04 2009-09-30 Millennium Pharm Inc ANTAGONISTS AGAINST THE PGD2 RECEPTOR FOR THE TREATMENT OF INFLAMMATORY DISEASES
GB0327912D0 (en) * 2003-12-02 2004-01-07 Glaxo Group Ltd Medicament
BRPI0608553A2 (pt) * 2005-02-24 2010-01-12 Millennium Pharm Inc antagonistas de receptor de pgd2 para o tratamento de doenças inflamatórias

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2024516C1 (ru) * 1989-02-02 1994-12-15 Яманути Фармасьютикал Ко., Лтд. Способ получения производного тетрагидробензимидазола или его фармацевтически приемлемой соли
US4902695A (en) * 1989-02-13 1990-02-20 Eli Lilly And Company Excitatory amino acid receptor antagonists
US5231102A (en) * 1989-03-08 1993-07-27 Merck Sharp & Dohme, Ltd. Tetrahydroquinoline derivatives useful for neurodegenerative disorders
ATE147732T1 (de) * 1989-03-08 1997-02-15 Merck Sharp & Dohme Tetrahydroquinolin-derivate, verwendbar bei neurodegenerativen krankheiten
US5529999A (en) 1994-03-04 1996-06-25 Eli Lilly And Company Antitumor compositions and methods of treatment
PL186781B1 (pl) * 1995-09-29 2004-02-27 Glaxo Wellcome Spa Nowy związek, pochodna tetrahydrochinoliny, sposób wytwarzania pochodnej tetrahydrochinoliny, środek farmaceutyczny i zastosowanie
GB9617305D0 (en) * 1996-08-17 1996-09-25 Glaxo Wellcome Spa Heterocyclic compounds
MY125037A (en) * 1998-06-10 2006-07-31 Glaxo Wellcome Spa 1,2,3,4 tetrahydroquinoline derivatives

Also Published As

Publication number Publication date
EA003276B1 (ru) 2003-04-24
NO20006227L (no) 2001-02-08
CZ20004587A3 (en) 2001-05-16
CO5080785A1 (es) 2001-09-25
US20020169186A1 (en) 2002-11-14
TWI229079B (en) 2005-03-11
DE69926632D1 (de) 2005-09-15
ATE301650T1 (de) 2005-08-15
MY125037A (en) 2006-07-31
EP1086093B1 (en) 2005-08-10
AR018632A1 (es) 2001-11-28
PL344694A1 (en) 2001-11-19
NO20006227D0 (no) 2000-12-07
PE20000724A1 (es) 2000-08-17
KR20010052722A (ko) 2001-06-25
HUP0102767A3 (en) 2003-01-28
EE200000733A (et) 2002-06-17
ES2249010T3 (es) 2006-03-16
DE69926632T2 (de) 2006-01-19
HRP20000845A2 (en) 2001-10-31
WO1999064411A1 (en) 1999-12-16
JP2002517492A (ja) 2002-06-18
EP1086093A1 (en) 2001-03-28
EA200001165A1 (ru) 2001-06-25
AP2000002008A0 (en) 2000-12-31
CA2334727A1 (en) 1999-12-16
BR9911145A (pt) 2001-03-06
NO321904B1 (no) 2006-07-17
CA2334727C (en) 2009-08-04
OA11564A (en) 2004-05-24
AU753867B2 (en) 2002-10-31
IL140062A (en) 2007-05-15
BG105123A (bg) 2001-11-30
HUP0102767A2 (hu) 2001-12-28
US6413985B1 (en) 2002-07-02
CN1173970C (zh) 2004-11-03
US6362199B1 (en) 2002-03-26
US20020052391A1 (en) 2002-05-02
IS5746A (is) 2000-11-30
IL140062A0 (en) 2002-02-10
PL197160B1 (pl) 2008-03-31
DK1086093T3 (da) 2005-11-28
US6495566B2 (en) 2002-12-17
HK1034079A1 (en) 2001-10-12
CZ293605B6 (cs) 2004-06-16
NZ508638A (en) 2003-08-29
TR200003652T2 (tr) 2001-04-20
AU4509299A (en) 1999-12-30
KR100586762B1 (ko) 2006-06-08
CN1311785A (zh) 2001-09-05

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