ID24669A - Turunan-turunan dolastatin 15 - Google Patents

Turunan-turunan dolastatin 15

Info

Publication number
ID24669A
ID24669A IDW20000322A ID20000322A ID24669A ID 24669 A ID24669 A ID 24669A ID W20000322 A IDW20000322 A ID W20000322A ID 20000322 A ID20000322 A ID 20000322A ID 24669 A ID24669 A ID 24669A
Authority
ID
Indonesia
Prior art keywords
dolastatin
Prior art date
Application number
IDW20000322A
Other languages
English (en)
Indonesian (id)
Inventor
Janssen Bernd
Barlozzari Teresa
Haupt Andreas
Zierke Thomas
Kling Andreas
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of ID24669A publication Critical patent/ID24669A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
IDW20000322A 1997-07-18 1998-07-07 Turunan-turunan dolastatin 15 ID24669A (id)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/896,394 US6143721A (en) 1997-07-18 1997-07-18 Dolastatin 15 derivatives
PCT/US1998/013901 WO1999003879A1 (en) 1997-07-18 1998-07-07 Dolastatin 15 derivatives

Publications (1)

Publication Number Publication Date
ID24669A true ID24669A (id) 2000-07-27

Family

ID=25406130

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20000322A ID24669A (id) 1997-07-18 1998-07-07 Turunan-turunan dolastatin 15

Country Status (32)

Country Link
US (6) US6143721A (OSRAM)
EP (1) EP0991658B1 (OSRAM)
JP (4) JP4508413B2 (OSRAM)
KR (1) KR100579748B1 (OSRAM)
CN (1) CN1268636C (OSRAM)
AR (1) AR018501A1 (OSRAM)
AT (1) ATE314387T1 (OSRAM)
AU (1) AU750120B2 (OSRAM)
BG (1) BG65212B1 (OSRAM)
BR (1) BR9810911A (OSRAM)
CA (1) CA2296036C (OSRAM)
CO (1) CO4990967A1 (OSRAM)
CY (1) CY1107047T1 (OSRAM)
CZ (1) CZ303045B6 (OSRAM)
DE (1) DE69832982T2 (OSRAM)
DK (1) DK0991658T3 (OSRAM)
ES (1) ES2258819T3 (OSRAM)
HR (1) HRP980397A2 (OSRAM)
HU (1) HU228996B1 (OSRAM)
ID (1) ID24669A (OSRAM)
IL (1) IL133784A (OSRAM)
MY (1) MY135057A (OSRAM)
NO (1) NO326827B1 (OSRAM)
NZ (1) NZ502296A (OSRAM)
PL (1) PL197884B1 (OSRAM)
PT (1) PT991658E (OSRAM)
RU (1) RU2195462C2 (OSRAM)
SK (1) SK286581B6 (OSRAM)
TR (2) TR200103545T2 (OSRAM)
TW (1) TW533217B (OSRAM)
WO (1) WO1999003879A1 (OSRAM)
ZA (1) ZA986358B (OSRAM)

Families Citing this family (28)

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US20010009901A1 (en) 1996-12-11 2001-07-26 Basf Aktiengesellschaft Germany Antineoplastic peptides
US6143721A (en) * 1997-07-18 2000-11-07 Basf Aktiengesellschaft Dolastatin 15 derivatives
US6686336B2 (en) 2000-02-08 2004-02-03 Federal Government As Represented By The Department Of Veterans Affaires N-terminal D(-)-penicillamine peptides as aldehyde sequestration agents
US6884869B2 (en) * 2001-04-30 2005-04-26 Seattle Genetics, Inc. Pentapeptide compounds and uses related thereto
US7256257B2 (en) * 2001-04-30 2007-08-14 Seattle Genetics, Inc. Pentapeptide compounds and uses related thereto
JP5042444B2 (ja) 2002-03-22 2012-10-03 エーザイ・アール・アンド・ディー・マネジメント株式会社 癌の処置におけるヘミアスタリン誘導体およびその利用法
US7064211B2 (en) * 2002-03-22 2006-06-20 Eisai Co., Ltd. Hemiasterlin derivatives and uses thereof
EP2353611B1 (en) * 2002-07-31 2015-05-13 Seattle Genetics, Inc. Drug conjugates and their use for treating cancer, an autoimmune disease or an infectious disease
KR101520209B1 (ko) 2003-11-06 2015-05-13 시애틀 지네틱스, 인크. 리간드에 접합될 수 있는 모노메틸발린 화합물
WO2006063135A2 (en) * 2004-12-09 2006-06-15 Eisai R & D Management Co., Ltd. Tubulin isotype screnning in cancer therapy using hemiasterlin analogs
CA2607940C (en) 2005-05-18 2009-12-15 Aegera Therapeutics Inc. Bir domain binding compounds
SG171682A1 (en) 2006-05-16 2011-06-29 Aegera Therapeutics Inc Iap bir domain binding compounds
SG183044A1 (en) 2007-07-16 2012-08-30 Genentech Inc Humanized anti-cd79b antibodies and immunoconjugatesand methods of use
JP5469600B2 (ja) 2007-07-16 2014-04-16 ジェネンテック， インコーポレイテッド 抗ＣＤ７９ｂ抗体及びイムノコンジュゲートとその使用方法
DE102007039706A1 (de) 2007-08-22 2009-02-26 Erhard Prof. Dr.-Ing. Kohn Chemischer Sensor auf Diamantschichten
UA106586C2 (uk) 2008-01-31 2014-09-25 Дженентек, Інк. Анти-cd79b антитіла, і імунокон'югати та способи їх застосування
NZ600608A (en) 2009-12-18 2015-01-30 Idenix Pharmaceuticals Inc 5,5-fused arylene or heteroarylene hepatitis c virus inhibitors
TW201129384A (en) 2010-02-10 2011-09-01 Immunogen Inc CD20 antibodies and uses thereof
EP3263583A1 (en) 2010-02-12 2018-01-03 Pharmascience Inc. Iap bir domain binding compounds
AU2012395148B2 (en) 2012-11-24 2016-10-27 Hangzhou Dac Biotech Co., Ltd. Hydrophilic linkers and their uses for conjugation of drugs to cell binding molecules
PT3122757T (pt) 2014-02-28 2023-11-03 Hangzhou Dac Biotech Co Ltd Ligantes carregados e as suas utilizações em conjugação
EP3689910A3 (en) 2014-09-23 2020-12-02 F. Hoffmann-La Roche AG Method of using anti-cd79b immunoconjugates
NZ737471A (en) 2015-06-15 2022-02-25 Hangzhou Dac Biotech Co Ltd Hydrophilic linkers for conjugation
WO2015151081A2 (en) 2015-07-12 2015-10-08 Suzhou M-Conj Biotech Co., Ltd Bridge linkers for conjugation of a cell-binding molecule
US9839687B2 (en) 2015-07-15 2017-12-12 Suzhou M-Conj Biotech Co., Ltd. Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule
WO2018086139A1 (en) 2016-11-14 2018-05-17 Hangzhou Dac Biotech Co., Ltd Conjugation linkers, cell binding molecule-drug conjugates containing the likers, methods of making and uses such conjugates with the linkers
AU2022338463A1 (en) 2021-09-03 2024-03-21 Toray Industries, Inc. Pharmaceutical composition for cancer treatment and/or prevention
JP2024541058A (ja) 2021-11-03 2024-11-06 ハンジョウ ディーエーシー バイオテック シーオー．，エルティディ． 抗体の特異的共役

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816444A (en) * 1987-07-10 1989-03-28 Arizona Board Of Regents, Arizona State University Cell growth inhibitory substance
US4879278A (en) * 1989-05-16 1989-11-07 Arizona Board Of Regents Isolation and structural elucidation of the cytostatic linear depsipeptide dolastatin 15
ES2144421T3 (es) * 1991-08-09 2000-06-16 Teikoku Hormone Mfg Co Ltd Nuevo derivado tetrapeptidico.
US5533097A (en) * 1992-02-26 1996-07-02 Motorola, Inc. Portable communication system comprising a local and wide area communication units which can store a communication when the wide area communication system is not available
WO1993017388A1 (en) 1992-02-26 1993-09-02 Clark Paul C System for protecting computers via intelligent tokens or smart cards
JP3523253B2 (ja) * 1992-05-20 2004-04-26 アボット ゲーエムベーハー ウント カンパニー カーゲー ドラスタチン誘導体
US5831002A (en) * 1992-05-20 1998-11-03 Basf Aktiengesellschaft Antitumor peptides
DE69329425T2 (de) * 1992-12-16 2001-01-18 Basf Ag Dolastatin analog
US5554993A (en) 1994-01-04 1996-09-10 Panasonic Technologies, Inc. Global position determining system and method
US5504191A (en) * 1994-08-01 1996-04-02 Arizona Board Of Regents Acting On Behalf Of Arizona State University Human cancer inhibitory pentapeptide methyl esters
US5530097A (en) * 1994-08-01 1996-06-25 Arizona Board Of Regents Acting On Behalf Of Arizona State University Human cancer inhibitory peptide amides
US5554725A (en) * 1994-09-14 1996-09-10 Arizona Board Of Regents Acting On Behalf Of Arizona State University Synthesis of dolastatin 15
US5663149A (en) * 1994-12-13 1997-09-02 Arizona Board Of Regents Acting On Behalf Of Arizona State University Human cancer inhibitory pentapeptide heterocyclic and halophenyl amides
US5618232A (en) 1995-03-23 1997-04-08 Martin; John R. Dual mode gaming device methods and systems
US5970143A (en) 1995-11-22 1999-10-19 Walker Asset Management Lp Remote-auditing of computer generated outcomes, authenticated billing and access control, and software metering system using cryptographic and other protocols
US5807984A (en) * 1995-11-09 1998-09-15 Basf Aktienegesellschaft Oligopeptides, the preparation and use thereof
TW474946B (en) * 1995-12-15 2002-02-01 Basf Ag Novel compounds, the preparation and use thereof
AU728161B2 (en) 1997-01-10 2001-01-04 Silicon Gaming, Inc. Method and apparatus using geoographical position and a universal time to determination means to provide authenticated, secure, on-line communication between remote gaming locations
US6143721A (en) * 1997-07-18 2000-11-07 Basf Aktiengesellschaft Dolastatin 15 derivatives
US6554705B1 (en) 1997-08-22 2003-04-29 Blake Cumbers Passive biometric customer identification and tracking system
US6629591B1 (en) 2001-01-12 2003-10-07 Igt Smart token
US6438382B1 (en) 2001-02-14 2002-08-20 Telefonaktiebolaget Lm Ericsson (Publ.) Expedited location determination in analog service areas

Also Published As

Publication number Publication date
NO20000231L (no) 2000-01-17
TW533217B (en) 2003-05-21
DE69832982D1 (de) 2006-02-02
IL133784A (en) 2005-09-25
CZ2000176A3 (en) 2001-06-13
MY135057A (en) 2008-01-31
AR018501A1 (es) 2001-11-28
EP0991658A1 (en) 2000-04-12
CO4990967A1 (es) 2000-12-26
HU228996B1 (hu) 2013-07-29
JP2001515010A (ja) 2001-09-18
DK0991658T3 (da) 2006-05-15
CN1268636C (zh) 2006-08-09
SK286581B6 (sk) 2009-01-07
NZ502296A (en) 2002-02-01
US7662786B2 (en) 2010-02-16
SK187999A3 (en) 2000-09-12
JP5122429B2 (ja) 2013-01-16
US20100099843A1 (en) 2010-04-22
PT991658E (pt) 2006-05-31
BR9810911A (pt) 2000-08-01
JP5047935B2 (ja) 2012-10-10
AU8475898A (en) 1999-02-10
TR200103545T2 (tr) 2002-06-21
TR200000132T2 (tr) 2000-05-22
CA2296036C (en) 2007-05-01
HRP980397A2 (en) 1999-04-30
KR20010021998A (ko) 2001-03-15
BG65212B1 (bg) 2007-07-31
NO20000231D0 (no) 2000-01-17
EP0991658B1 (en) 2005-12-28
US20030153505A1 (en) 2003-08-14
BG104089A (en) 2000-12-29
JP4508413B2 (ja) 2010-07-21
US20130046077A1 (en) 2013-02-21
US6143721A (en) 2000-11-07
IL133784A0 (en) 2001-04-30
RU2195462C2 (ru) 2002-12-27
ES2258819T3 (es) 2006-09-01
US6458765B1 (en) 2002-10-01
WO1999003879A1 (en) 1999-01-28
KR100579748B1 (ko) 2006-05-15
US8163698B2 (en) 2012-04-24
ATE314387T1 (de) 2006-01-15
AU750120B2 (en) 2002-07-11
HUP0004234A2 (hu) 2001-05-28
PL338144A1 (en) 2000-09-25
CN1264388A (zh) 2000-08-23
JP2012211164A (ja) 2012-11-01
CY1107047T1 (el) 2012-09-26
DE69832982T2 (de) 2006-08-24
JP2009137967A (ja) 2009-06-25
US7084110B2 (en) 2006-08-01
PL197884B1 (pl) 2008-05-30
HK1029125A1 (en) 2001-03-23
ZA986358B (en) 2000-01-17
CA2296036A1 (en) 1999-01-28
CZ303045B6 (cs) 2012-03-07
NO326827B1 (no) 2009-02-23
US20060270606A1 (en) 2006-11-30
HUP0004234A3 (en) 2001-08-28
JP2009137968A (ja) 2009-06-25

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