HUP9903410A2 - Tolfenámsavat vagy gyógyszerészetileg elfogadható sóját tartalmazó, gyors hatóanyag-leadású tabletta - Google Patents

Tolfenámsavat vagy gyógyszerészetileg elfogadható sóját tartalmazó, gyors hatóanyag-leadású tabletta

Info

Publication number
HUP9903410A2
HUP9903410A2 HU9903410A HUP9903410A HUP9903410A2 HU P9903410 A2 HUP9903410 A2 HU P9903410A2 HU 9903410 A HU9903410 A HU 9903410A HU P9903410 A HUP9903410 A HU P9903410A HU P9903410 A2 HUP9903410 A2 HU P9903410A2
Authority
HU
Hungary
Prior art keywords
weight
active ingredient
pharmaceutically acceptable
acceptable salt
release tablet
Prior art date
Application number
HU9903410A
Other languages
English (en)
Inventor
Karen Bjornsdottir
Lars Hedevang Christensen
Knud Erik Gebhard-Hansen
Soren Bols Pedersen
Original Assignee
A/S Gea Farmaceutisk Fabrik
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by A/S Gea Farmaceutisk Fabrik filed Critical A/S Gea Farmaceutisk Fabrik
Publication of HUP9903410A2 publication Critical patent/HUP9903410A2/hu
Publication of HUP9903410A3 publication Critical patent/HUP9903410A3/hu
Publication of HU224030B1 publication Critical patent/HU224030B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A találmány tárgyát hatóanyagként tőlfenámsavat vagy sóit tartalmazótabletták képezik, amelyek a hatóanyag győrs leadására képesek. Atalálmány szerinti tabletták 40-70 tömeg% hatóanyagőt, 2,5-5,0 tömeg%alginsavat vagy sóját, 6-10 tömeg% intragranűlált nátriűm-keményítőglikőlátőt, 3-5 tömeg% extragranűlált nátriűm-keményítő glikőlátőt és1-3 tömeg% extragranűlált térhálósítőtt nátriűm-karbőximetil-cellűlózttartalmaznak, valamint szőkásős tablettakészítési segédanyagőkat. Atalálmány szerinti tabletták 1/2 órával a beadás űtán a tőlfenámsavnakkörülbelül 2,00 mg/ml közepes plazmakőncentrációját tűdjákbiztősítani. ŕ
HU9903410A 1995-12-20 1996-12-19 Tolfenámsavat vagy gyógyszerészetileg elfogadható sóját tartalmazó, gyors hatóanyag-leadású tabletta HU224030B1 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK144895 1995-12-20
PCT/DK1996/000548 WO1997022340A1 (en) 1995-12-20 1996-12-19 Rapid release tablet comprising tolfenamic acid or a pharmaceutically acceptable salt thereof

Publications (3)

Publication Number Publication Date
HUP9903410A2 true HUP9903410A2 (hu) 2000-04-28
HUP9903410A3 HUP9903410A3 (en) 2000-05-29
HU224030B1 HU224030B1 (hu) 2005-05-30

Family

ID=8104933

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9903410A HU224030B1 (hu) 1995-12-20 1996-12-19 Tolfenámsavat vagy gyógyszerészetileg elfogadható sóját tartalmazó, gyors hatóanyag-leadású tabletta

Country Status (27)

Country Link
US (1) US6036975A (hu)
EP (1) EP0869783B1 (hu)
JP (1) JP2000515489A (hu)
CN (1) CN1147295C (hu)
AR (1) AR004395A1 (hu)
AT (1) ATE234085T1 (hu)
AU (1) AU1190097A (hu)
BR (1) BR9612057A (hu)
CA (1) CA2244396A1 (hu)
CZ (1) CZ293422B6 (hu)
DE (1) DE69626676T2 (hu)
DK (1) DK0869783T3 (hu)
EE (1) EE9800186A (hu)
ES (1) ES2191781T3 (hu)
HR (1) HRP960598A2 (hu)
HU (1) HU224030B1 (hu)
IL (1) IL124356A (hu)
MX (1) MX9803918A (hu)
NO (1) NO316869B1 (hu)
NZ (1) NZ324674A (hu)
PL (1) PL186915B1 (hu)
RO (1) RO117589B1 (hu)
RU (1) RU2166939C2 (hu)
TR (1) TR199801126T2 (hu)
TW (1) TW430561B (hu)
WO (1) WO1997022340A1 (hu)
ZA (1) ZA9610714B (hu)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9802973D0 (sv) 1998-09-03 1998-09-03 Astra Ab Immediate release tablet
US6599530B2 (en) * 1998-09-14 2003-07-29 Orion Corporation Oral compacted composition comprising catechol derivatives
US6660303B2 (en) * 1999-12-06 2003-12-09 Edward Mendell & Co. Pharmaceutical superdisintegrant
CA2311734C (en) * 2000-04-12 2011-03-08 Bristol-Myers Squibb Company Flash-melt oral dosage formulation
WO2005028621A2 (en) * 2003-09-15 2005-03-31 Vitra Bioscience, Inc. Assays with primary cells
EP1998763A4 (en) * 2006-03-24 2010-03-03 Texas A & M Univ System And Sa USES OF DIPHENYLCARBOXYLIC ACIDS AND CARBOXYLIC ACIDS WITH DIPHENYLAMINE FUNCTION
TWI405574B (zh) * 2007-06-21 2013-08-21 Otsuka Pharma Co Ltd 藥學固體製劑及其製造方法
US8367427B2 (en) * 2008-08-20 2013-02-05 Baxter International Inc. Methods of processing compositions containing microparticles
NZ751112A (en) * 2016-09-07 2024-03-22 Celgene Corp Tablet compositions
CN111184707B (zh) * 2020-02-20 2021-04-27 中山大学 托芬那酸或其药学上可接受的盐在制备预防和/或治疗新型冠状病毒炎症药物中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE116061C (hu) *
FI89004C (fi) * 1988-02-16 1993-08-10 Pertti J Neuvonen Anvaendning av tillsatsmedel foer oekning av absorptionshastigheten av laekemedel i orala laekemedelspreparat
IT1276689B1 (it) * 1995-06-09 1997-11-03 Applied Pharma Res Forma farmaceutica solida ad uso orale

Also Published As

Publication number Publication date
HUP9903410A3 (en) 2000-05-29
IL124356A0 (en) 1998-12-06
PL186915B1 (pl) 2004-03-31
ES2191781T3 (es) 2003-09-16
ATE234085T1 (de) 2003-03-15
AR004395A1 (es) 1998-11-04
CZ293422B6 (cs) 2004-04-14
AU1190097A (en) 1997-07-14
EP0869783B1 (en) 2003-03-12
CN1147295C (zh) 2004-04-28
EP0869783A1 (en) 1998-10-14
CN1208345A (zh) 1999-02-17
TW430561B (en) 2001-04-21
JP2000515489A (ja) 2000-11-21
NO316869B1 (no) 2004-06-07
CA2244396A1 (en) 1997-06-26
HU224030B1 (hu) 2005-05-30
DE69626676T2 (de) 2003-12-18
NO982875L (no) 1998-08-19
ZA9610714B (en) 1997-06-30
RU2166939C2 (ru) 2001-05-20
NO982875D0 (no) 1998-06-19
BR9612057A (pt) 1999-02-23
WO1997022340A1 (en) 1997-06-26
IL124356A (en) 2001-05-20
PL327584A1 (en) 1998-12-21
HRP960598A2 (en) 1998-02-28
TR199801126T2 (xx) 1998-08-21
DE69626676D1 (de) 2003-04-17
US6036975A (en) 2000-03-14
RO117589B1 (ro) 2002-05-30
EE9800186A (et) 1998-12-15
CZ194398A3 (cs) 1998-11-11
MX9803918A (es) 1998-09-30
DK0869783T3 (da) 2003-06-02
NZ324674A (en) 2000-01-28

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HFG4 Patent granted, date of granting

Effective date: 20050322

NF4A Restoration of patent protection
MM4A Lapse of definitive patent protection due to non-payment of fees