HUP9901577A2 - Javított eljárások nemkovalens kötésekkel komplexbe vitt és multivalens proteoszóma alegységvakcinák előállítására - Google Patents

Javított eljárások nemkovalens kötésekkel komplexbe vitt és multivalens proteoszóma alegységvakcinák előállítására

Info

Publication number
HUP9901577A2
HUP9901577A2 HU9901577A HUP9901577A HUP9901577A2 HU P9901577 A2 HUP9901577 A2 HU P9901577A2 HU 9901577 A HU9901577 A HU 9901577A HU P9901577 A HUP9901577 A HU P9901577A HU P9901577 A2 HUP9901577 A2 HU P9901577A2
Authority
HU
Hungary
Prior art keywords
sub
production
improved methods
covalently complexed
unit vaccines
Prior art date
Application number
HU9901577A
Other languages
English (en)
Inventor
James F. Wood
Wendell D. Zollinger
Georg H. Lowell
Original Assignee
United States Army Medical Research Materiel Command
Georg H. Lowell
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21707938&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP9901577(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by United States Army Medical Research Materiel Command, Georg H. Lowell filed Critical United States Army Medical Research Materiel Command
Publication of HUP9901577A2 publication Critical patent/HUP9901577A2/hu
Publication of HUP9901577A3 publication Critical patent/HUP9901577A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
    • A23J1/008—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from microorganisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1275—Lipoproteins; Chylomicrons; Artificial HDL, LDL, VLDL, protein-free species thereof; Precursors thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/25—Shigella (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Oncology (AREA)
  • Dispersion Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Mycology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)

Abstract

A találmány tárgyát prőteőszóma-amphiphil determináns vakcinákképezik, amelyeket parenterális, illetve főleg nyálkahártyán keresztültörténő beadásra terveztek, beleértve, a légűti (azaz példáűl azintrana- zális, az intrapharyngeális, és intrapűlmőnáris), a gasztrő-intesztinális (azaz őrális vagy rektális), vagy tőpikális (azazkötőhártyán vagy a fülön keresztül) való beadást, hőgy ezzel mindszisztémás (szérűm) mind nyálkahártya (beleértve a légúti ésbélrendszeri) ellenanyagválaszt indűkáljanak. ŕ
HU9901577A 1995-09-18 1996-09-18 Improved methods for the production of non-covalently complexed and multivalent proteosome sub-unit vaccines HUP9901577A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US385995P 1995-09-18 1995-09-18

Publications (2)

Publication Number Publication Date
HUP9901577A2 true HUP9901577A2 (hu) 1999-08-30
HUP9901577A3 HUP9901577A3 (en) 2000-03-28

Family

ID=21707938

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9901577A HUP9901577A3 (en) 1995-09-18 1996-09-18 Improved methods for the production of non-covalently complexed and multivalent proteosome sub-unit vaccines

Country Status (20)

Country Link
US (1) US6476201B1 (hu)
EP (1) EP0854729B2 (hu)
JP (2) JP4033489B2 (hu)
KR (1) KR19990045763A (hu)
CN (1) CN1211192A (hu)
AT (1) ATE261313T1 (hu)
BR (1) BR9610484A (hu)
CA (1) CA2232410C (hu)
CZ (1) CZ298460B6 (hu)
DE (1) DE69631835T3 (hu)
DK (1) DK0854729T3 (hu)
EA (1) EA199800208A1 (hu)
ES (1) ES2217325T5 (hu)
HU (1) HUP9901577A3 (hu)
IL (1) IL123720A (hu)
MX (1) MX9802128A (hu)
NO (1) NO320074B1 (hu)
PL (1) PL325604A1 (hu)
PT (1) PT854729E (hu)
WO (1) WO1997010844A1 (hu)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5961970A (en) 1993-10-29 1999-10-05 Pharmos Corporation Submicron emulsions as vaccine adjuvants
US8007815B1 (en) * 1998-05-29 2011-08-30 Novartis Ag Combination meningitidis B/C vaccines
CN100392082C (zh) 1999-04-30 2008-06-04 启龙股份公司 保守的奈瑟球菌抗原
DK2270173T3 (en) * 1999-05-19 2016-03-07 Glaxosmithkline Biolog Sa Neisserial combination compositions
US6743900B2 (en) 2000-02-15 2004-06-01 Id Biomedical Corporation Of Quebec Proteosome influenza vaccine
EP1721618A3 (en) * 2000-02-15 2007-01-10 ID Biomedical Corporation of Quebec Proteosome influenza vaccine composition
MXPA02008314A (es) 2000-02-28 2002-12-09 Chiron Spa Expresion heterologa de proteinas de neisseria.
MXPA03008154A (es) * 2001-03-09 2004-11-12 Id Biomedical Corp Quebec Novedoso adyuvante de vacuna de proteosoma-liposacarido.
WO2004015099A2 (en) * 2002-08-02 2004-02-19 Glaxosmithkline Biologicals Sa Vaccine composition comprising lipooligosaccharide with reduced phase variability
CA2501812C (en) 2002-10-11 2012-07-10 Mariagrazia Pizza Polypeptide-vaccines for broad protection against hypervirulent meningococcal lineages
US7255867B2 (en) * 2002-11-15 2007-08-14 Id Biomedical Corporation Of Quebec Vaccine
GB0316560D0 (en) * 2003-07-15 2003-08-20 Chiron Srl Vesicle filtration
US7368537B2 (en) * 2003-07-15 2008-05-06 Id Biomedical Corporation Of Quebec Subunit vaccine against respiratory syncytial virus infection
JP2007505836A (ja) * 2003-09-15 2007-03-15 アイディー バイオメディカル コーポレイション オブ ケベック 麻疹サブユニットワクチン
ES2615169T3 (es) * 2003-10-22 2017-06-05 Id Biomedical Corporation Of Quebec Composiciones y procedimientos de activación de la inmunidad innata y alérgica
RU2387453C2 (ru) 2004-06-25 2010-04-27 АйДи БАЙОМЕДИКАЛ КОРПОРЕЙШН ОФ КВЕБЕК Композиции и способы лечения неврологических нарушений
JP2008505114A (ja) * 2004-06-30 2008-02-21 アイディー バイオメディカル コーポレイション オブ ケベック コロナウイルス感染を処置するためのワクチン組成物
US7552948B2 (en) 2006-03-29 2009-06-30 Tokai Rubber Industries, Ltd. Quick connector
CN110064053A (zh) * 2006-08-07 2019-07-30 哈佛大学校长及研究员协会 蛋白质基质疫苗及这种疫苗的制备和给药方法
MX2009001412A (es) 2006-08-07 2009-04-24 Harvard College Vacunas de matriz de proteinas y metodos de hacer y administrar tales vacunas.
JP2010502425A (ja) * 2006-08-30 2010-01-28 ジーイー・ヘルスケア・バイオサイエンス・コーポレイション 膜を評価するシステム及び方法並びに膜濾過装置
AU2009262893B2 (en) * 2008-05-30 2015-05-21 The U.S.A., as represented by The Secretary of the Army, on behalf of Walter Reed Army Institute Of Research Meningococcal multivalent native outer membrane vesicle vaccine, methods of making and use thereof
US20120231086A1 (en) * 2009-09-09 2012-09-13 Killen Kevin P Protein matrix vaccines of improved immunogenicity
EP4183408A1 (en) * 2014-09-24 2023-05-24 The United States of America as Represented by The Secretary of the Navy Combined enterotoxigenic escherichia coli and shigella recombinant
EP4277654A1 (en) 2021-01-18 2023-11-22 Conserv Bioscience Limited Coronavirus immunogenic compositions, methods and uses thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4707543A (en) * 1985-09-17 1987-11-17 The United States Of America As Represented By The Secretary Of The Army Process for the preparation of detoxified polysaccharide-outer membrane protein complexes, and their use as antibacterial vaccines
RU1522494C (ru) * 1987-06-16 1994-11-15 Научно-производственное объединение "Иммунопрепарат" Способ получения инактивированной вакцины гриппа
RU2023448C1 (ru) * 1987-07-30 1994-11-30 Сентро Насьональ Де Биопрепарадос Способ получения вакцины против различных патогенных серотипов менингита нейссера группы в
US5145702A (en) * 1988-09-19 1992-09-08 Opta Food Ingredients, Inc. Hydrophobic protein microparticles and preparation thereof
ES2070312T5 (es) * 1988-12-19 2003-05-16 American Cyanamid Co Vacuna de proteina de membrana exterior meningococica de clase 1.
US5102989A (en) * 1991-03-15 1992-04-07 Merck & Co., Inc. Method of stabilizing recombinant hepatitis B virus surface proteins from recombinant host cells
CA2139517A1 (en) * 1992-07-20 1994-02-03 Paul M. Keller Immunological conjugates of ompc and hiv-specific selected principal neutralization epitopes
US5576016A (en) * 1993-05-18 1996-11-19 Pharmos Corporation Solid fat nanoemulsions as drug delivery vehicles
AU5543294A (en) * 1993-10-29 1995-05-22 Pharmos Corp. Submicron emulsions as vaccine adjuvants
US6743900B2 (en) * 2000-02-15 2004-06-01 Id Biomedical Corporation Of Quebec Proteosome influenza vaccine

Also Published As

Publication number Publication date
HUP9901577A3 (en) 2000-03-28
KR19990045763A (ko) 1999-06-25
EP0854729B2 (en) 2008-10-22
CA2232410C (en) 2003-06-17
DK0854729T3 (da) 2004-07-12
WO1997010844A1 (en) 1997-03-27
US6476201B1 (en) 2002-11-05
IL123720A (en) 2002-02-10
CA2232410A1 (en) 1997-03-27
EP0854729A4 (en) 2000-02-02
EA199800208A1 (ru) 1998-10-29
CZ298460B6 (cs) 2007-10-10
JP4033489B2 (ja) 2008-01-16
ES2217325T3 (es) 2004-11-01
EP0854729A1 (en) 1998-07-29
DE69631835D1 (de) 2004-04-15
JP2004099619A (ja) 2004-04-02
ATE261313T1 (de) 2004-03-15
BR9610484A (pt) 2001-09-11
CN1211192A (zh) 1999-03-17
NO981189D0 (no) 1998-03-17
US20020164357A1 (en) 2002-11-07
NO981189L (no) 1998-05-14
IL123720A0 (en) 1998-10-30
EP0854729B1 (en) 2004-03-10
DE69631835T2 (de) 2005-02-10
PL325604A1 (en) 1998-08-03
NO320074B1 (no) 2005-10-17
CZ81998A3 (cs) 1998-10-14
PT854729E (pt) 2004-08-31
JP2000507913A (ja) 2000-06-27
ES2217325T5 (es) 2009-04-01
MX9802128A (es) 1998-11-29
DE69631835T3 (de) 2009-03-05

Similar Documents

Publication Publication Date Title
HUP9901577A2 (hu) Javított eljárások nemkovalens kötésekkel komplexbe vitt és multivalens proteoszóma alegységvakcinák előállítására
HUP0303800A2 (hu) Gyógyszerkészítmények, adagolási formák epotilonok orális beadására
HUP0402192A2 (hu) EGF receptor elleni antitesteket tartalmazó liofilizált készítmény
HUP0400442A2 (hu) Kémiailag módosított inzulin pulmonáris beadása és eljárás az előállítására
NO20004413D0 (no) HIV peptider, antigener, vaksine, blandinger, immunoassay, kit og en fremgangmÕte for pÕvisning av antistoffer som blir infusert av HIV
CY1110820T1 (el) Εμβολια συνδυασμου για neisseria meningitidis
HUP0302874A2 (hu) Eljárás risperidon előállítására
FR2729068B1 (fr) Dispositif de suspension de rideau de fenetre
HUP9700884A2 (hu) Tienil-etilamino-halogénfenil-acetamid intermedierek és eljárás előállításukra
HUP0003636A2 (hu) Analgetikum-kombináció
AR052142A1 (es) Perla recubierta enterica que comprende ixabepilona, y preparacion y administracion de la misma
ID22942A (id) Penggunaan antibodi burung
BR0016941A (pt) Derivados de aminometil-fenil-ciclohexanona
HUP0204145A2 (hu) Eljárás egy kinolil-akrilnitril-származék és közbenső terméke előállítására és az új intermedier
HUP0301666A2 (hu) A II. típusú gonadotropin-felszabadító hormon receptora és azt kódoló polinukleotid
FR2819696B1 (fr) Fermoir pour boucles d'oreilles
FI974376A0 (fi) Pneumokokkaalisten antigeenien annostelu suun kautta
IT1286307B1 (it) Virus mixomatoso ricombinante, suo impiego per la produzione di un vaccino e relativo vaccino.
IE32592B1 (en) New substituted anthranilic acid and its salts,their production and use
TW200607812A (en) Prevention, treament and detection of porcine progressive atrophic rhinitis
Tasso Tumore adenomatoide dell'epididimo
USD198389S (en) Charm pendant
Stepanshin et al. Mycobacterium tuberculosis drug resistant strains and their epidemic importance
ATE326482T1 (de) Anti-petasin-antikörper, verfahren zu ihrer herstellung und ihre verwendung
JPS62141324U (hu)