HUP9701904A2 - D-panolakton hidroláz és az azt kódoló gén - Google Patents

D-panolakton hidroláz és az azt kódoló gén

Info

Publication number
HUP9701904A2
HUP9701904A2 HU9701904A HUP9701904A HUP9701904A2 HU P9701904 A2 HUP9701904 A2 HU P9701904A2 HU 9701904 A HU9701904 A HU 9701904A HU P9701904 A HUP9701904 A HU P9701904A HU P9701904 A2 HUP9701904 A2 HU P9701904A2
Authority
HU
Hungary
Prior art keywords
panthlactone
proteins
subject
production
host cells
Prior art date
Application number
HU9701904A
Other languages
English (en)
Inventor
Tatsuhiko Kobayashi
Keiji Sakamoto
Sakayu Shimizu
Hideaki Yamada
Original Assignee
Fuji Yakuhin Kogyo Kabushiki Kaisha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fuji Yakuhin Kogyo Kabushiki Kaisha filed Critical Fuji Yakuhin Kogyo Kabushiki Kaisha
Publication of HUP9701904A2 publication Critical patent/HUP9701904A2/hu
Publication of HUP9701904A3 publication Critical patent/HUP9701904A3/hu
Publication of HU222434B1 publication Critical patent/HU222434B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/001—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by metabolizing one of the enantiomers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

A találmány tárgyát D,L-pantőlaktőn - D-szelektív aszimmetrikűshidrőlízis útján történő - őptikai főrgatóképesség szerintiszétválasztására alkalmas új enzimek, valamint az azőkat kódőló génekképezik. A találmány tárgyát közelebbről Fűsariűm őxyspőrűmban előállítőtt,természetes D-pantőlaktőn hidrőláz aktivitással vagy annak lényegébenmegfelelő aktivitással rendelkező prőteinek, valamint az azőkat kódőlógének képezik. A találmány tárgyát képezik tővábbá, az említettprőteineket kódőló nűkleőtidszekvenciákat tartalmazó DNS-ek, a DNS-ekkel transzfőrmált vagy transzfektált gazdasejtek, valamint eljárásőka D-pantőlaktőn hidrőláz prőteinek előállítására, a találmány szerintigazdasejtek alkalmazásával. A találmány tárgyáhőz tartőzik ezen felül,az említett prőteinek és gazdasejtek alkalmazása is, D-pantőlaktőnelőállításásra. A találmány szerinti megőldás előnyösen alkalmazható D-pantőlaktőnipari méretű előállítására. ŕ
HU9701904A 1995-09-13 1996-09-13 D-pantolakton hidroláz és azt kódoló gén HU222434B1 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP25945195 1995-09-13
PCT/JP1996/002620 WO1997010341A1 (fr) 1995-09-13 1996-09-13 D-pantolactone hydrolase et gene codant ladite substance

Publications (3)

Publication Number Publication Date
HUP9701904A2 true HUP9701904A2 (hu) 1998-03-02
HUP9701904A3 HUP9701904A3 (en) 1998-06-29
HU222434B1 HU222434B1 (hu) 2003-07-28

Family

ID=17334256

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9701904A HU222434B1 (hu) 1995-09-13 1996-09-13 D-pantolakton hidroláz és azt kódoló gén

Country Status (12)

Country Link
US (2) US6406898B1 (hu)
EP (1) EP0794251B1 (hu)
JP (1) JP3830165B2 (hu)
CN (1) CN1121497C (hu)
AU (1) AU1810197A (hu)
CA (1) CA2204743C (hu)
DE (1) DE69634815T2 (hu)
ES (1) ES2242968T3 (hu)
HU (1) HU222434B1 (hu)
MX (1) MX221102B (hu)
RU (1) RU2218405C2 (hu)
WO (1) WO1997010341A1 (hu)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6395529B1 (en) 1998-11-10 2002-05-28 Novozymes Biotech, Inc. Polypeptides having lactonohydrolase activity and nucleic acids encoding same
AU1909900A (en) * 1998-11-10 2000-05-29 Novozymes Biotech, Inc. Polypeptides having lactonohydrolase activity and nucleic acids encoding same
AU3503800A (en) 1999-02-24 2001-05-30 Novozymes Biotech, Inc. Methods for using lactonohydrolases in baking
KR20020043254A (ko) * 1999-10-29 2002-06-08 스타르크, 카르크 Ｌ-판토락톤 가수분해 효소 및 ｄ-판토락톤의 제조 방법
US7407746B2 (en) * 2001-02-08 2008-08-05 Ngk Insulators, Ltd. Biochip and method for producing the same
WO2004078951A1 (ja) * 2003-03-03 2004-09-16 Daiichi Fine Chemical Co., Ltd. ラクトナーゼの製法およびその利用
JP4571936B2 (ja) * 2003-03-28 2010-10-27 ディーエスエム アイピー アセッツ ビー．ブイ． パントラクトンヒドロラーゼ
RU2349599C2 (ru) 2004-03-26 2009-03-20 Поско Биоадгезив мидии
UA110323C2 (en) * 2009-06-04 2015-12-25 Promedior Inc Derivative of serum amyloid p and their receipt and application
CN113046337B (zh) * 2021-03-18 2023-04-07 赤峰制药股份有限公司 一种泛解酸内酯水解酶突变体菌株及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5572182A (en) * 1978-11-28 1980-05-30 Sagami Chem Res Center Optical resolution of pantolactone
JPS62294094A (ja) 1986-06-12 1987-12-21 Sanaka Tsutomu モノクロ−ナル抗体
JPH0667320B2 (ja) * 1986-06-13 1994-08-31 三菱化成株式会社 Ｄ−パントラクトンの製造法
JPH0655156B2 (ja) * 1986-06-13 1994-07-27 三菱化成株式会社 Ｄｌ−パントラクトンの光学分割法
JP2844354B2 (ja) * 1989-08-03 1999-01-06 富士薬品工業株式会社 Ｄ―パントラクトンの製造法
JP3011449B2 (ja) * 1990-10-05 2000-02-21 富士薬品工業株式会社 Ｄ―パントラクトン加水分解酵素およびその製造法

Also Published As

Publication number Publication date
EP0794251A1 (en) 1997-09-10
EP0794251A4 (en) 2000-01-12
DE69634815T2 (de) 2006-03-23
MX221102B (es) 2004-06-23
DE69634815D1 (de) 2005-07-14
HUP9701904A3 (en) 1998-06-29
ES2242968T3 (es) 2005-11-16
EP0794251B1 (en) 2005-06-08
CN1121497C (zh) 2003-09-17
CA2204743A1 (en) 1997-03-20
HU222434B1 (hu) 2003-07-28
CN1166182A (zh) 1997-11-26
MX9703475A (es) 1997-07-31
US6794171B2 (en) 2004-09-21
US20030124697A1 (en) 2003-07-03
AU1810197A (en) 1997-04-01
US6406898B1 (en) 2002-06-18
RU2218405C2 (ru) 2003-12-10
JP3830165B2 (ja) 2006-10-04
WO1997010341A1 (fr) 1997-03-20
CA2204743C (en) 2008-09-02

Similar Documents

Publication Publication Date Title
HUP0004484A2 (hu) Deszaturázgének és alkalmazásaik
DE69229126D1 (de) Verfahren zur Herstellung von Thrombin
DE69636288D1 (de) Samenstrenung resistenz
HUP9900078A2 (hu) Eljárás O-acetilszerin, L-cisztein és L-cisztein-származékok előállítására
ES2010763A6 (es) Un metodo para producir una nitrilasa especifica capaz de hidrolizar un p-hidroxibenzonitrilo dihalogenado en 3,5.
ATE213019T1 (de) Chimäre oligomere mit einer rns- spaltungsaktivität
BR9814404A (pt) " clonagem de expressão em fungos filamentosos "
AR056723A2 (es) Polipeptido purificado metodo para producirlo , metodo para identificarlo y/ o aislarlo composicion farmaceutica que lo comprende, secuencia de acidos nucleicos aislada que codifica dicho polipeptido, vector que contiene a dicha secuencia celula huesped transfectada por dicho vector, sonda nucleotid
DE69638314D1 (de) Zirkuläres DNA Molekül mit einem abhängigen Replikationsursprung, seine Herstellungsverfahren und seine Verwendung in der Gentherapie
BR0003943A (pt) Sequências de nucleotìdeo que codificam para o gene thre e processo para a produção enzimática de l-treonina usando bactérias corineforma
ATE391175T1 (de) Multidrug resistenz gen
HUP9701904A2 (hu) D-panolakton hidroláz és az azt kódoló gén
ATE195346T1 (de) Rekombinante dna moleküle die aminopeptidase enzyme kodieren und ihre anwendung für die herstellung von impfstoffen gegen helminth infektionen
ATE304595T1 (de) Lichtproduzierender biosensor
DE3787998T2 (de) ART-Nukleotidsegmente, -Vektoren, -Zellinien, Verfahren zur Herstellung und Verwendung.
DE69405230D1 (de) Prostaglandinrezeptor ep1 kodierende dna
ATE338129T1 (de) Herstellung gegen sclerotinia sclerotiorum resistenter pflanzendurch einführung eines für oxalatoxydase kodierenden gens
ES2070125T3 (es) Factor de crecimiento fibroblastico acido mutante.
ATE175995T1 (de) Gen für die ataxia-telangiectasia komplementationsgruppe d
ATE271609T1 (de) Mch3, eine apoptosis-protease, kodierende nukleinsäuren und methoden zur verwendung
DE3782560T2 (de) Hefestaemme zur expression fremder gene.
HUP9801681A2 (hu) Mutáns proteinek
HUP0103208A2 (hu) Proteáz kódoló szekvenciákat vagy inhibítoraikat tartalmazó DNS konstrukciók
HUP0203724A2 (hu) Humán heparanázzal rokon polipeptidek és nukleinsavak
ATE332974T1 (de) Il-1/tnf-alpha-activated kinase (itak), und verfahren zu ihrer herstellung und verwendung

Legal Events

Date Code Title Description
HFG4 Patent granted, date of granting

Effective date: 20030512

MM4A Lapse of definitive patent protection due to non-payment of fees