AR056723A2 - Polipeptido purificado metodo para producirlo , metodo para identificarlo y/ o aislarlo composicion farmaceutica que lo comprende, secuencia de acidos nucleicos aislada que codifica dicho polipeptido, vector que contiene a dicha secuencia celula huesped transfectada por dicho vector, sonda nucleotid - Google Patents

Polipeptido purificado metodo para producirlo , metodo para identificarlo y/ o aislarlo composicion farmaceutica que lo comprende, secuencia de acidos nucleicos aislada que codifica dicho polipeptido, vector que contiene a dicha secuencia celula huesped transfectada por dicho vector, sonda nucleotid

Info

Publication number
AR056723A2
AR056723A2 ARP060104650A ARP060104650A AR056723A2 AR 056723 A2 AR056723 A2 AR 056723A2 AR P060104650 A ARP060104650 A AR P060104650A AR P060104650 A ARP060104650 A AR P060104650A AR 056723 A2 AR056723 A2 AR 056723A2
Authority
AR
Argentina
Prior art keywords
polypeptide
ducted
acid sequence
vector
nucleic acid
Prior art date
Application number
ARP060104650A
Other languages
English (en)
Inventor
Daniel Caput
Patrick Laurent Ferrara
Natalio Vita
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9485198&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR056723(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of AR056723A2 publication Critical patent/AR056723A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

Polipéptido purificado, que comprende una secuencia de aminoácidos elegida entre: a) la secuencia SEC ID No.2, b) toda secuencia biologicamente activa derivada de SEC ID No. 2 y capaz de ligarse específicamente a la IL-13. Se proporciona además, un método para producirlo, un método para identificarlo y/o aislarlo, una composicion farmacéutica que lo comprende, la secuencia de ácidos nucléicos aislada que codifica a dicho polipéptido, También se proporciona un vector que contiene a dicha secuencia, una célula huésped transfectada con dicho vector, una sonda nucleotídica y una secuencia antisentido. Además se describen las utilizaciones de dicho polipéptido, secuencia y sonda.
ARP060104650A 1995-12-06 2006-10-25 Polipeptido purificado metodo para producirlo , metodo para identificarlo y/ o aislarlo composicion farmaceutica que lo comprende, secuencia de acidos nucleicos aislada que codifica dicho polipeptido, vector que contiene a dicha secuencia celula huesped transfectada por dicho vector, sonda nucleotid AR056723A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9514424A FR2742156A1 (fr) 1995-12-06 1995-12-06 Polypeptide recepteur de l'il-13
PCT/FR1996/001756 WO1997020926A1 (fr) 1995-12-06 1996-11-07 Polypeptide recepteur de l'il-i3

Publications (1)

Publication Number Publication Date
AR056723A2 true AR056723A2 (es) 2007-10-17

Family

ID=9485198

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP960105500A AR004860A1 (es) 1995-12-06 1996-12-05 Anticuerpos mono o policionales, anticuerpos conjugados, o sus fragmentos, su utilizacion y metodo de diagnostico in vitro de patologias correlacionadas con una expresion anormal del receptor de la il-13, a partir de muestras biologicas susceptibles de contener el receptor de la il-13 expresado a un nivel anormal
ARP060104650A AR056723A2 (es) 1995-12-06 2006-10-25 Polipeptido purificado metodo para producirlo , metodo para identificarlo y/ o aislarlo composicion farmaceutica que lo comprende, secuencia de acidos nucleicos aislada que codifica dicho polipeptido, vector que contiene a dicha secuencia celula huesped transfectada por dicho vector, sonda nucleotid

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ARP960105500A AR004860A1 (es) 1995-12-06 1996-12-05 Anticuerpos mono o policionales, anticuerpos conjugados, o sus fragmentos, su utilizacion y metodo de diagnostico in vitro de patologias correlacionadas con una expresion anormal del receptor de la il-13, a partir de muestras biologicas susceptibles de contener el receptor de la il-13 expresado a un nivel anormal

Country Status (19)

Country Link
US (4) US7928073B2 (es)
EP (1) EP0876482B1 (es)
JP (3) JP3415162B2 (es)
AR (2) AR004860A1 (es)
AT (1) ATE234922T1 (es)
AU (1) AU7576096A (es)
BR (1) BR9611697B1 (es)
CA (1) CA2238893C (es)
DE (1) DE69626859T2 (es)
DK (1) DK0876482T3 (es)
ES (1) ES2192620T3 (es)
FR (1) FR2742156A1 (es)
MX (1) MX9804419A (es)
MY (1) MY123740A (es)
NO (3) NO324775B1 (es)
PT (1) PT876482E (es)
TW (1) TW565570B (es)
WO (1) WO1997020926A1 (es)
ZA (1) ZA9610238B (es)

Families Citing this family (30)

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US6911530B1 (en) 1995-10-23 2005-06-28 Amrad Operations, Pty., Ltd. Haemopoietin receptor and genetic sequences encoding same
EP0907730B1 (en) * 1995-10-23 2009-10-07 Zenyth Operations Pty Ltd Haemopoietin receptor and genetic sequences encoding same
US5710023A (en) 1996-03-01 1998-01-20 Genetics Institute, Inc. IL-13 cytokine receptor chain
US7078494B1 (en) 1996-03-01 2006-07-18 Genetics Institute, Llc Antibodies to human IL-13bc and methods of their use in inhibiting IL-13 binding
EP0812913A3 (en) * 1996-06-12 1999-08-04 Smithkline Beecham Corporation HR-1 receptor, a receptor of the cytokine receptors family
WO1998010638A1 (en) * 1996-09-10 1998-03-19 Amrad Operations Pty. Ltd. Therapeutic molecules
GB9625899D0 (en) * 1996-12-13 1997-01-29 Glaxo Group Ltd Substances and their uses
US6743604B1 (en) 1996-12-13 2004-06-01 Smithkline Beecham Corporation Substances and their uses
US7198789B2 (en) 1998-03-17 2007-04-03 Genetics Institute, Llc Methods and compositions for modulating interleukin-21 receptor activity
US7189400B2 (en) 1998-03-17 2007-03-13 Genetics Institute, Llc Methods of treatment with antagonists of MU-1
US6057128A (en) 1998-03-17 2000-05-02 Genetics Institute, Inc. MU-1, member of the cytokine receptor family
CA2235420A1 (en) 1998-06-17 1999-12-17 Paolo Renzi Antisense oligonucleotides for treating or preventing atopic diseases and neoplastic cell proliferation
US7553487B2 (en) 1998-12-14 2009-06-30 Genetics Institute, Llc Method and compositions for treating asthma
MXPA01006006A (es) 1998-12-14 2004-08-12 Genetics Inst Cadena receptora de citocina.
US20020197266A1 (en) * 2000-02-08 2002-12-26 Waldemar Debinski Immunotherapy using interleukin 13 receptor subunit alpha 2
EP1268794A2 (en) * 2000-04-07 2003-01-02 Heska Corporation Compositions and methods related to canine igg and canine il-13 receptors
CA2491320A1 (en) 2002-07-15 2004-01-22 Wyeth Methods and compositions for modulating t helper (th) cell development and function
JP4943161B2 (ja) 2003-12-23 2012-05-30 ジェネンテック， インコーポレイテッド 新規抗ｉｌ１３モノクローナル抗体での癌の処置
AR049390A1 (es) 2004-06-09 2006-07-26 Wyeth Corp Anticuerpos contra la interleuquina-13 humana y usos de los mismos
US20090098142A1 (en) * 2004-06-09 2009-04-16 Kasaian Marion T Methods and compositions for treating and monitoring treatment of IL-13-associated disorders
US7501121B2 (en) 2004-06-17 2009-03-10 Wyeth IL-13 binding agents
BRPI0517387A8 (pt) 2004-10-29 2017-07-11 Topigen Pharmaceuticals Inc Oligonucleotídeos anti-senso para o tratamento de alergia e proliferação de células neoplásicas
WO2006055638A2 (en) 2004-11-17 2006-05-26 Abgenix, Inc. Fully human monoclonal antibodies to il-13
GB0615881D0 (en) * 2006-08-10 2006-09-20 Univ Southampton Novel peptide for treatment of asthma
MX2009011366A (es) * 2007-04-23 2009-11-05 Wyeth Corp Metodos y composiciones para tratar y monitorear el tratamiento de trastornos asociados con il-13.
WO2013112871A1 (en) 2012-01-27 2013-08-01 The Board Of Trustees Of The Leland Stanford Junior University Therapeutic il-13 polypeptides
WO2014152361A1 (en) 2013-03-15 2014-09-25 Wake Forest University Health Sciences Antibodies against human and canine il-13ra2
NZ756749A (en) 2013-09-13 2022-05-27 Genentech Inc Methods and compositions comprising purified recombinant polypeptides
RU2016107435A (ru) 2013-09-13 2017-10-18 Дженентек, Инк. Композиции и способы обнаружения и количественного определения белка клеток-хозяев в клеточных линиях и рекомбинантные полипептидные продукты
WO2015042706A1 (en) 2013-09-24 2015-04-02 Medicenna Therapeutics Pte Ltd Interleukin-4 receptor-binding fusion proteins and uses thereof

Family Cites Families (7)

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Publication number Priority date Publication date Assignee Title
US4554101A (en) * 1981-01-09 1985-11-19 New York Blood Center, Inc. Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
US4946778A (en) * 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
ES2136092T3 (es) * 1991-09-23 1999-11-16 Medical Res Council Procedimientos para la produccion de anticuerpos humanizados.
US5596072A (en) 1992-08-21 1997-01-21 Schering Corporation Method of refolding human IL-13
US5587459A (en) * 1994-08-19 1996-12-24 Regents Of The University Of Minnesota Immunoconjugates comprising tyrosine kinase inhibitors
US6911530B1 (en) * 1995-10-23 2005-06-28 Amrad Operations, Pty., Ltd. Haemopoietin receptor and genetic sequences encoding same
US5710023A (en) * 1996-03-01 1998-01-20 Genetics Institute, Inc. IL-13 cytokine receptor chain

Also Published As

Publication number Publication date
ZA9610238B (en) 1998-06-05
DE69626859T2 (de) 2003-12-24
US20050282216A1 (en) 2005-12-22
NO331148B1 (no) 2011-10-24
US20110201029A1 (en) 2011-08-18
MX9804419A (es) 1998-09-30
JP2005323595A (ja) 2005-11-24
ATE234922T1 (de) 2003-04-15
NO324775B1 (no) 2007-12-10
NO20092994L (no) 1998-08-05
EP0876482B1 (fr) 2003-03-19
NO328197B1 (no) 2010-01-04
WO1997020926A1 (fr) 1997-06-12
MY123740A (en) 2006-06-30
TW565570B (en) 2003-12-11
US20060035856A1 (en) 2006-02-16
AR004860A1 (es) 1999-03-10
JP4185070B2 (ja) 2008-11-19
CA2238893A1 (fr) 1997-06-12
JPH11511028A (ja) 1999-09-28
ES2192620T3 (es) 2003-10-16
PT876482E (pt) 2003-07-31
CA2238893C (fr) 2013-10-08
JP2003180382A (ja) 2003-07-02
DE69626859D1 (de) 2003-04-24
JP3415162B2 (ja) 2003-06-09
AU7576096A (en) 1997-06-27
NO982550D0 (no) 1998-06-04
US7928073B2 (en) 2011-04-19
DK0876482T3 (da) 2003-07-21
US20060035855A1 (en) 2006-02-16
NO20074034L (no) 1998-08-05
FR2742156A1 (fr) 1997-06-13
NO982550L (no) 1998-08-05
JP3737793B2 (ja) 2006-01-25
BR9611697A (pt) 1999-02-17
US8318910B2 (en) 2012-11-27
BR9611697B1 (pt) 2013-09-17
EP0876482A1 (fr) 1998-11-11

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