MX9703475A - D-pantolactona hidrolasa y gen que codifica para la misma. - Google Patents

D-pantolactona hidrolasa y gen que codifica para la misma.

Info

Publication number
MX9703475A
MX9703475A MX9703475A MX9703475A MX9703475A MX 9703475 A MX9703475 A MX 9703475A MX 9703475 A MX9703475 A MX 9703475A MX 9703475 A MX9703475 A MX 9703475A MX 9703475 A MX9703475 A MX 9703475A
Authority
MX
Mexico
Prior art keywords
same
gene encoding
protein
host cells
pantolactone
Prior art date
Application number
MX9703475A
Other languages
English (en)
Other versions
MX221102B (es
Inventor
Keiji Sakamoto
Hideaki Yamada
Sakayu Shimizu
Michihiko Kobayashi
Original Assignee
Fuji Yakuhin Kogyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fuji Yakuhin Kogyo Kk filed Critical Fuji Yakuhin Kogyo Kk
Publication of MX9703475A publication Critical patent/MX9703475A/es
Publication of MX221102B publication Critical patent/MX221102B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/001—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by metabolizing one of the enantiomers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Se proporciona una enzima novedosa la cual es util en la resolucion optica de D-pantolactona por medio de hidrolisis asimétrica D-selectiva, y un gen que codifica para la misma. La invencion describe el gen que codifica para D-pantolactona hidrolasa natural (por ejemplo, uno que se origina en Fusarium oxysporum) o para proteínas que tienen una actividad sustancialmente equivalente a la misma, células huésped transformadas con ADN que contiene una secuencia de nucleotidos que codifica para la proteína, procesos para producir la proteína por medio de utilizacion de tales células huésped y usos de las proteínas y de las células huésped.
MX9703475A 1995-09-13 1996-09-13 D-pantolactona hidrolasa y gen que codifica para la misma. MX221102B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP25945195 1995-09-13
PCT/JP1996/002620 WO1997010341A1 (en) 1995-09-13 1996-09-13 D-pantolactone hydrolase and gene encoding the same

Publications (2)

Publication Number Publication Date
MX9703475A true MX9703475A (es) 1997-07-31
MX221102B MX221102B (es) 2004-06-23

Family

ID=17334256

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9703475A MX221102B (es) 1995-09-13 1996-09-13 D-pantolactona hidrolasa y gen que codifica para la misma.

Country Status (12)

Country Link
US (2) US6406898B1 (es)
EP (1) EP0794251B1 (es)
JP (1) JP3830165B2 (es)
CN (1) CN1121497C (es)
AU (1) AU1810197A (es)
CA (1) CA2204743C (es)
DE (1) DE69634815T2 (es)
ES (1) ES2242968T3 (es)
HU (1) HU222434B1 (es)
MX (1) MX221102B (es)
RU (1) RU2218405C2 (es)
WO (1) WO1997010341A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6395529B1 (en) 1998-11-10 2002-05-28 Novozymes Biotech, Inc. Polypeptides having lactonohydrolase activity and nucleic acids encoding same
CN1354795A (zh) * 1998-11-10 2002-06-19 诺沃奇梅兹生物技术有限公司 具有内酯水解酶活性的多肽和编码该多肽的核酸
AU3503800A (en) 1999-02-24 2001-05-30 Novozymes Biotech, Inc. Methods for using lactonohydrolases in baking
CA2389064A1 (en) * 1999-10-29 2001-05-10 Maria Kesseler L-pantolactone-hydrolase and a method for producing d-pantolactone
US7407746B2 (en) * 2001-02-08 2008-08-05 Ngk Insulators, Ltd. Biochip and method for producing the same
AU2004217677B2 (en) * 2003-03-03 2008-09-11 Daiichi Fine Chemical Co., Ltd. Process for producing lactonase and utilization thereof
WO2004085651A2 (en) * 2003-03-28 2004-10-07 Dsm Ip Assets B.V. Pantolactone hydrolase
ATE494300T1 (de) * 2004-03-26 2011-01-15 Postech Foundation Biologischer klebstoff aus muscheln
UA110323C2 (en) * 2009-06-04 2015-12-25 Promedior Inc Derivative of serum amyloid p and their receipt and application
KR102268921B1 (ko) * 2019-12-10 2021-06-23 강원대학교산학협력단 p53을 활성화하는 펩타이드를 포함하는 조성물
CN113046337B (zh) * 2021-03-18 2023-04-07 赤峰制药股份有限公司 一种泛解酸内酯水解酶突变体菌株及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5572182A (en) * 1978-11-28 1980-05-30 Sagami Chem Res Center Optical resolution of pantolactone
JPS62294094A (ja) 1986-06-12 1987-12-21 Sanaka Tsutomu モノクロ−ナル抗体
JPH0655156B2 (ja) * 1986-06-13 1994-07-27 三菱化成株式会社 Ｄｌ−パントラクトンの光学分割法
JPH0667320B2 (ja) * 1986-06-13 1994-08-31 三菱化成株式会社 Ｄ−パントラクトンの製造法
JP2844354B2 (ja) 1989-08-03 1999-01-06 富士薬品工業株式会社 Ｄ―パントラクトンの製造法
JP3011449B2 (ja) * 1990-10-05 2000-02-21 富士薬品工業株式会社 Ｄ―パントラクトン加水分解酵素およびその製造法

Also Published As

Publication number Publication date
US6794171B2 (en) 2004-09-21
DE69634815T2 (de) 2006-03-23
RU2218405C2 (ru) 2003-12-10
HUP9701904A2 (hu) 1998-03-02
US6406898B1 (en) 2002-06-18
HU222434B1 (hu) 2003-07-28
CA2204743A1 (en) 1997-03-20
JP3830165B2 (ja) 2006-10-04
WO1997010341A1 (en) 1997-03-20
HUP9701904A3 (en) 1998-06-29
AU1810197A (en) 1997-04-01
EP0794251B1 (en) 2005-06-08
ES2242968T3 (es) 2005-11-16
DE69634815D1 (de) 2005-07-14
EP0794251A4 (en) 2000-01-12
US20030124697A1 (en) 2003-07-03
EP0794251A1 (en) 1997-09-10
CN1166182A (zh) 1997-11-26
CN1121497C (zh) 2003-09-17
MX221102B (es) 2004-06-23
CA2204743C (en) 2008-09-02

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Legal Events

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FG Grant or registration
HC Change of company name or juridical status

Owner name: WINDFIN B.V.

MM Annulment or lapse due to non-payment of fees