HUP0500472A2 - Szepszis kezelése kis dózisú szöveti faktor bioszintézis inhibitor (TFPI) beadásával - Google Patents

Szepszis kezelése kis dózisú szöveti faktor bioszintézis inhibitor (TFPI) beadásával Download PDF

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Publication number
HUP0500472A2
HUP0500472A2 HU0500472A HUP0500472A HUP0500472A2 HU P0500472 A2 HUP0500472 A2 HU P0500472A2 HU 0500472 A HU0500472 A HU 0500472A HU P0500472 A HUP0500472 A HU P0500472A HU P0500472 A2 HUP0500472 A2 HU P0500472A2
Authority
HU
Hungary
Prior art keywords
tfpi
ala
analog
dose
dose rate
Prior art date
Application number
HU0500472A
Other languages
English (en)
Hungarian (hu)
Inventor
Alba A. Creasey
Original Assignee
Chiron Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corporation filed Critical Chiron Corporation
Publication of HUP0500472A2 publication Critical patent/HUP0500472A2/hu

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • A61K38/57Protease inhibitors from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y10/00Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nanotechnology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Theoretical Computer Science (AREA)
  • Mathematical Physics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
HU0500472A 2001-10-15 2002-10-15 Szepszis kezelése kis dózisú szöveti faktor bioszintézis inhibitor (TFPI) beadásával HUP0500472A2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32880601P 2001-10-15 2001-10-15
PCT/US2002/032625 WO2003055442A2 (en) 2001-10-15 2002-10-15 Treatment of sepsis by low dose administration of tissue factor pathway inhibitor (tfpi)

Publications (1)

Publication Number Publication Date
HUP0500472A2 true HUP0500472A2 (hu) 2005-08-29

Family

ID=23282520

Family Applications (2)

Application Number Title Priority Date Filing Date
HU0500472A HUP0500472A2 (hu) 2001-10-15 2002-10-15 Szepszis kezelése kis dózisú szöveti faktor bioszintézis inhibitor (TFPI) beadásával
HU0501111A HUP0501111A2 (en) 2001-10-15 2002-10-15 Treatment of severe pneumonia by administration of tissue factor pathway inhibitor

Family Applications After (1)

Application Number Title Priority Date Filing Date
HU0501111A HUP0501111A2 (en) 2001-10-15 2002-10-15 Treatment of severe pneumonia by administration of tissue factor pathway inhibitor

Country Status (17)

Country Link
US (2) US7674769B2 (enExample)
EP (2) EP1446140A4 (enExample)
JP (5) JP2005515214A (enExample)
KR (2) KR20050036867A (enExample)
CN (2) CN1604787A (enExample)
AU (2) AU2002365131B2 (enExample)
BR (2) BR0213293A (enExample)
CA (2) CA2463655A1 (enExample)
EA (2) EA200400549A1 (enExample)
HU (2) HUP0500472A2 (enExample)
IL (2) IL161408A0 (enExample)
IS (2) IS7223A (enExample)
MX (2) MXPA04003547A (enExample)
NO (2) NO20041997D0 (enExample)
PL (2) PL372138A1 (enExample)
WO (2) WO2003032904A2 (enExample)
ZA (2) ZA200403601B (enExample)

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KR20050036867A (ko) 2001-10-15 2005-04-20 카이론 코포레이션 조직인자경로 억제제(tfpi)의 투여에 의한 중증폐렴의 치료
JP2008500942A (ja) * 2003-01-08 2008-01-17 カイロン コーポレイション 組織因子経路インヒビターまたは組織因子経路インヒビター改変体を含有する安定化凍結乾燥組成物
WO2005019265A1 (en) 2003-08-13 2005-03-03 Chiron Corporation Improved method of purifying tfpi and tfpi analogs
CA2560103A1 (en) * 2004-03-17 2005-11-24 Chiron Corporation Treatment of severe community-acquired pneumonia by administration of tissue factor pathway inhibitor (tfpi)
MX2007012619A (es) * 2005-04-15 2008-01-11 Novartis Vaccines & Diagnostic Tratamiento de neumonia severa adquirida en comunidad por administracion de inhibidor de ruta de factor de tejido.
US20090214506A1 (en) * 2005-05-06 2009-08-27 Novartis Ag Use of TFPI to Treat Severe Bacterial Infections
CN102961746B (zh) 2005-05-16 2016-06-15 艾伯维生物技术有限公司 TNFα抑制剂治疗腐蚀性多关节炎的用途
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AU2006272653A1 (en) * 2005-07-22 2007-02-01 Novartis Ag TFPI fragments as anti-microbial agents
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US11504071B2 (en) 2018-04-10 2022-11-22 Hill-Rom Services, Inc. Patient risk assessment based on data from multiple sources in a healthcare facility
WO2020084853A1 (ja) 2018-10-22 2020-04-30 旭化成ファーマ株式会社 凝固異常を伴う敗血症の治療及び/又は改善のための医薬
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Also Published As

Publication number Publication date
WO2003055442A2 (en) 2003-07-10
WO2003032904A3 (en) 2004-03-04
BR0213293A (pt) 2004-12-21
US20030139340A1 (en) 2003-07-24
NO20041997D0 (no) 2004-05-14
IS7224A (is) 2004-04-15
ZA200403601B (en) 2006-06-28
MXPA04003547A (es) 2004-07-22
JP2006008704A (ja) 2006-01-12
AU2002365131B2 (en) 2007-03-01
JP2010006839A (ja) 2010-01-14
IL161407A0 (en) 2004-09-27
NO20041996D0 (no) 2004-05-14
US7674769B2 (en) 2010-03-09
CA2463738A1 (en) 2003-07-10
AU2002340183B2 (en) 2008-11-13
WO2003032904A2 (en) 2003-04-24
PL374506A1 (en) 2005-10-31
ZA200403690B (en) 2005-03-08
JP2005515214A (ja) 2005-05-26
JP2006008706A (ja) 2006-01-12
EP1446140A4 (en) 2007-03-07
MXPA04003548A (es) 2004-07-22
IL161408A0 (en) 2004-09-27
CN1604787A (zh) 2005-04-06
HUP0501111A2 (en) 2007-12-28
EP1446138A2 (en) 2004-08-18
EP1446138A4 (en) 2007-03-14
EA200400548A1 (ru) 2005-06-30
CN1604790A (zh) 2005-04-06
US20030139339A1 (en) 2003-07-24
JP2005506345A (ja) 2005-03-03
KR20050036867A (ko) 2005-04-20
WO2003055442A3 (en) 2004-03-04
AU2002365131A1 (en) 2003-07-15
PL372138A1 (en) 2005-07-11
CA2463655A1 (en) 2003-04-24
IS7223A (is) 2004-04-15
EP1446140A2 (en) 2004-08-18
EA200400549A1 (ru) 2005-02-24
BR0213292A (pt) 2006-05-23
KR20040040489A (ko) 2004-05-12

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