PL372138A1 - Treatment of sepsis by low dose administration of tissue factor pathway inhibitor (tfpi) - Google Patents
Treatment of sepsis by low dose administration of tissue factor pathway inhibitor (tfpi)Info
- Publication number
- PL372138A1 PL372138A1 PL02372138A PL37213802A PL372138A1 PL 372138 A1 PL372138 A1 PL 372138A1 PL 02372138 A PL02372138 A PL 02372138A PL 37213802 A PL37213802 A PL 37213802A PL 372138 A1 PL372138 A1 PL 372138A1
- Authority
- PL
- Poland
- Prior art keywords
- tfpi
- sepsis
- treatment
- low dose
- tissue factor
- Prior art date
Links
- 206010040047 Sepsis Diseases 0.000 title 1
- 102100030951 Tissue factor pathway inhibitor Human genes 0.000 title 1
- 108010013555 lipoprotein-associated coagulation inhibitor Proteins 0.000 title 1
- 101150070659 tfpI gene Proteins 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y10/00—Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Nanotechnology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Theoretical Computer Science (AREA)
- Mathematical Physics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Physics & Mathematics (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32880601P | 2001-10-15 | 2001-10-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL372138A1 true PL372138A1 (en) | 2005-07-11 |
Family
ID=23282520
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL02372138A PL372138A1 (en) | 2001-10-15 | 2002-10-15 | Treatment of sepsis by low dose administration of tissue factor pathway inhibitor (tfpi) |
| PL02374506A PL374506A1 (en) | 2001-10-15 | 2002-10-15 | Treatment of severe pneumonia by administration of tissue factor pathway inhibitor (tfpi) |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL02374506A PL374506A1 (en) | 2001-10-15 | 2002-10-15 | Treatment of severe pneumonia by administration of tissue factor pathway inhibitor (tfpi) |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US7674769B2 (enExample) |
| EP (2) | EP1446140A4 (enExample) |
| JP (5) | JP2005506345A (enExample) |
| KR (2) | KR20040040489A (enExample) |
| CN (2) | CN1604790A (enExample) |
| AU (2) | AU2002365131B2 (enExample) |
| BR (2) | BR0213293A (enExample) |
| CA (2) | CA2463655A1 (enExample) |
| EA (2) | EA200400549A1 (enExample) |
| HU (2) | HUP0501111A2 (enExample) |
| IL (2) | IL161407A0 (enExample) |
| IS (2) | IS7224A (enExample) |
| MX (2) | MXPA04003547A (enExample) |
| NO (2) | NO20041997D0 (enExample) |
| PL (2) | PL372138A1 (enExample) |
| WO (2) | WO2003032904A2 (enExample) |
| ZA (2) | ZA200403601B (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA200400549A1 (ru) * | 2001-10-15 | 2005-02-24 | Чирон Корпорейшн | Лечение сепсиса введением малых доз ингибитора пути тканевого фактора (tfpi) |
| CA2512680A1 (en) * | 2003-01-08 | 2004-07-29 | Chiron Corporation | Stabilized lyophilized compositions comprising tissue factor pathway inhibitor or tissue factor pathway inhibitor variants |
| JP4522997B2 (ja) * | 2003-08-13 | 2010-08-11 | ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド | Tfpiおよびtfpiアナログを精製するための改良された方法 |
| EP1729791A2 (en) * | 2004-03-17 | 2006-12-13 | Chiron Corporation | Treatment of severe community-acquired pneumonia by admistration of tissue factor pathway inhibitor (tfpi) |
| JP2008536859A (ja) * | 2005-04-15 | 2008-09-11 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス, インコーポレイテッド | 組織因子経路阻害剤(tfpi)の投与による重度の市中肺炎の処置 |
| KR20080017021A (ko) * | 2005-05-06 | 2008-02-25 | 노바티스 아게 | 중증 박테리아 감염을 치료하기 위한 tfpi의 용도 |
| BRPI0610058A2 (pt) | 2005-05-16 | 2010-05-25 | Abbott Biotech Ltd | uso de inibidor de tnf para tratamento da poliartrite erosiva |
| CN101262880A (zh) * | 2005-06-24 | 2008-09-10 | 德拉格雷丘尔公司 | 在影响呼吸道的炎症病状中气道施用组织因子途径抑制物 |
| CA2615777A1 (en) * | 2005-07-22 | 2007-02-01 | Novartis Ag | Tfpi fragments as anti-microbial agents |
| US9624295B2 (en) | 2006-04-10 | 2017-04-18 | Abbvie Biotechnology Ltd. | Uses and compositions for treatment of psoriatic arthritis |
| US20110142837A1 (en) * | 2007-07-20 | 2011-06-16 | Trustees Of The University Of Pennsylvania | Method Of Treating Acute Respiratory Distress Syndrome |
| WO2009129164A1 (en) * | 2008-04-15 | 2009-10-22 | Novartis Ag | Pharmaceutical combinations of tfpi-fragments and an antibiotic |
| UA112050C2 (uk) * | 2008-08-04 | 2016-07-25 | БАЄР ХЕЛСКЕР ЛЛСі | Терапевтична композиція, що містить моноклональне антитіло проти інгібітора шляху тканинного фактора (tfpi) |
| US20120148542A1 (en) | 2010-12-10 | 2012-06-14 | Lifeline Scientific, Inc. | Machine perfusion with complement inhibitors |
| WO2013011021A1 (en) | 2011-07-18 | 2013-01-24 | The University Of Melbourne | Use of c-fms antagonists |
| KR101672108B1 (ko) | 2011-11-15 | 2016-11-02 | 아사히 가세이 파마 가부시키가이샤 | 패혈증의 치료 및/또는 개선을 위한 의약 |
| SG11201507871XA (en) | 2013-04-12 | 2015-10-29 | Morphosys Ag | Antibodies targeting m-csf |
| US11908581B2 (en) | 2018-04-10 | 2024-02-20 | Hill-Rom Services, Inc. | Patient risk assessment based on data from multiple sources in a healthcare facility |
| US11504071B2 (en) | 2018-04-10 | 2022-11-22 | Hill-Rom Services, Inc. | Patient risk assessment based on data from multiple sources in a healthcare facility |
| WO2023142096A1 (en) * | 2022-01-30 | 2023-08-03 | Westlake University | Composition and method for preventing and/or treating clostridioides difficile infections caused by clade 2 strains |
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| EA200400549A1 (ru) | 2001-10-15 | 2005-02-24 | Чирон Корпорейшн | Лечение сепсиса введением малых доз ингибитора пути тканевого фактора (tfpi) |
| US20020198138A1 (en) | 2002-06-07 | 2002-12-26 | Macias William Louis | Combination therapy for the treatment of inflammatory and respiratory diseases |
-
2002
- 2002-10-15 EA EA200400549A patent/EA200400549A1/ru unknown
- 2002-10-15 AU AU2002365131A patent/AU2002365131B2/en not_active Ceased
- 2002-10-15 PL PL02372138A patent/PL372138A1/xx not_active Application Discontinuation
- 2002-10-15 EP EP02778529A patent/EP1446140A4/en not_active Withdrawn
- 2002-10-15 IL IL16140702A patent/IL161407A0/xx unknown
- 2002-10-15 BR BR0213293-1A patent/BR0213293A/pt not_active Application Discontinuation
- 2002-10-15 KR KR10-2004-7005632A patent/KR20040040489A/ko not_active Withdrawn
- 2002-10-15 HU HU0501111A patent/HUP0501111A2/hu unknown
- 2002-10-15 WO PCT/US2002/032624 patent/WO2003032904A2/en not_active Ceased
- 2002-10-15 CN CNA028249003A patent/CN1604790A/zh active Pending
- 2002-10-15 AU AU2002340183A patent/AU2002340183B2/en not_active Ceased
- 2002-10-15 CA CA002463655A patent/CA2463655A1/en not_active Abandoned
- 2002-10-15 WO PCT/US2002/032625 patent/WO2003055442A2/en not_active Ceased
- 2002-10-15 JP JP2003535710A patent/JP2005506345A/ja not_active Withdrawn
- 2002-10-15 HU HU0500472A patent/HUP0500472A2/hu unknown
- 2002-10-15 CA CA002463738A patent/CA2463738A1/en not_active Abandoned
- 2002-10-15 EP EP02803284A patent/EP1446138A4/en not_active Withdrawn
- 2002-10-15 EA EA200400548A patent/EA200400548A1/ru unknown
- 2002-10-15 KR KR1020047005618A patent/KR20050036867A/ko not_active Withdrawn
- 2002-10-15 US US10/270,478 patent/US7674769B2/en not_active Expired - Fee Related
- 2002-10-15 MX MXPA04003547A patent/MXPA04003547A/es unknown
- 2002-10-15 JP JP2003556020A patent/JP2005515214A/ja not_active Withdrawn
- 2002-10-15 PL PL02374506A patent/PL374506A1/xx not_active Application Discontinuation
- 2002-10-15 CN CNA028250648A patent/CN1604787A/zh active Pending
- 2002-10-15 BR BRPI0213292-3A patent/BR0213292A/pt unknown
- 2002-10-15 IL IL16140802A patent/IL161408A0/xx unknown
-
2003
- 2003-02-04 US US10/270,479 patent/US20030139340A1/en not_active Abandoned
-
2004
- 2004-04-15 MX MXPA04003548A patent/MXPA04003548A/es not_active Application Discontinuation
- 2004-04-15 IS IS7224A patent/IS7224A/is unknown
- 2004-04-15 IS IS7223A patent/IS7223A/is unknown
- 2004-05-11 ZA ZA200403601A patent/ZA200403601B/en unknown
- 2004-05-13 ZA ZA200403690A patent/ZA200403690B/xx unknown
- 2004-05-14 NO NO20041997A patent/NO20041997D0/no not_active Application Discontinuation
- 2004-05-14 NO NO20041996A patent/NO20041996D0/no not_active Application Discontinuation
-
2005
- 2005-09-16 JP JP2005271219A patent/JP2006008706A/ja active Pending
- 2005-09-16 JP JP2005271191A patent/JP2006008704A/ja not_active Withdrawn
-
2009
- 2009-10-09 JP JP2009235793A patent/JP2010006839A/ja not_active Withdrawn
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