ATE374181T1
(de)
|
2001-06-27 |
2007-10-15 |
Smithkline Beecham Corp |
Fluorpyrrolidine als dipeptidylpeptidaseinhibitoren
|
AU2003211931A1
(en)
*
|
2002-02-13 |
2003-09-04 |
Takeda Chemical Industries, Ltd. |
Jnk inhibitor
|
US7074798B2
(en)
|
2002-02-25 |
2006-07-11 |
Eisai Co., Ltd |
Xanthine derivative and DPPIV inhibitor
|
US7105526B2
(en)
|
2002-06-28 |
2006-09-12 |
Banyu Pharmaceuticals Co., Ltd. |
Benzimidazole derivatives
|
EP1527049B8
(en)
|
2002-08-08 |
2008-10-29 |
Takeda Pharmaceutical Company Limited |
Fused heterocyclic compounds as peptidase inhibitors
|
US7407955B2
(en)
|
2002-08-21 |
2008-08-05 |
Boehringer Ingelheim Pharma Gmbh & Co., Kg |
8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
|
US20060039974A1
(en)
*
|
2002-09-11 |
2006-02-23 |
Takeda Pharmaceutical Company Limited |
Sustained release preparation
|
WO2004054979A1
(ja)
*
|
2002-12-18 |
2004-07-01 |
Takeda Pharmaceutical Company Limited |
Jnk阻害剤
|
ATE496893T1
(de)
|
2002-12-20 |
2011-02-15 |
X Ceptor Therapeutics Inc |
Isochinolinonderivate und deren verwendung als medikamente
|
US7772188B2
(en)
|
2003-01-28 |
2010-08-10 |
Ironwood Pharmaceuticals, Inc. |
Methods and compositions for the treatment of gastrointestinal disorders
|
EP1604983A4
(en)
*
|
2003-03-17 |
2008-06-25 |
Takeda Pharmaceutical |
Receptor Antagonists
|
US7687625B2
(en)
*
|
2003-03-25 |
2010-03-30 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
WO2005004863A1
(en)
*
|
2003-07-11 |
2005-01-20 |
Merck Patent Gmbh |
Benzimidazole carboxamides as raf kinase inhibitors
|
US7678909B1
(en)
|
2003-08-13 |
2010-03-16 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
CN1867560A
(zh)
*
|
2003-08-13 |
2006-11-22 |
武田药品工株式会社 |
4-嘧啶酮衍生物及其作为肽基肽酶抑制剂的用途
|
US7169926B1
(en)
|
2003-08-13 |
2007-01-30 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
JP2007505121A
(ja)
*
|
2003-09-08 |
2007-03-08 |
武田薬品工業株式会社 |
ジペプチジルぺプチダーゼ阻害剤
|
EP1697342A2
(en)
*
|
2003-09-08 |
2006-09-06 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
CA2551037A1
(en)
|
2003-09-22 |
2005-03-31 |
Banyu Pharmaceutical Co., Ltd. |
Novel piperidine derivative
|
WO2005046578A2
(en)
*
|
2003-09-23 |
2005-05-26 |
Merck & Co., Inc. |
Isoquinolinone potassium channel inhibitors
|
CN1856477A
(zh)
|
2003-09-23 |
2006-11-01 |
默克公司 |
异喹啉钾通道抑制剂
|
AU2004276267B2
(en)
*
|
2003-09-23 |
2010-08-19 |
Merck Sharp & Dohme Corp. |
Isoquinolinone potassium channel inhibitors
|
KR20150028829A
(ko)
|
2003-11-17 |
2015-03-16 |
노파르티스 아게 |
디펩티딜 펩티다제 ⅳ 억제제의 용도
|
ES2940341T3
(es)
|
2004-01-20 |
2023-05-05 |
Novartis Ag |
Formulación y proceso de compresión directa
|
EP1712547B1
(en)
*
|
2004-02-05 |
2011-12-14 |
Kyorin Pharmaceutical Co., Ltd. |
Bicycloester derivative
|
EP1717225A4
(en)
*
|
2004-02-18 |
2009-10-21 |
Kyorin Seiyaku Kk |
BICYCLIC AMIDE DERIVATIVES
|
US7514571B2
(en)
*
|
2004-02-27 |
2009-04-07 |
Kyorin Pharmaceutical Co., Ltd. |
Bicyclo derivative
|
US7732446B1
(en)
|
2004-03-11 |
2010-06-08 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
CN102079743B
(zh)
*
|
2004-03-15 |
2020-08-25 |
武田药品工业株式会社 |
二肽基肽酶抑制剂
|
CN1938286A
(zh)
|
2004-03-29 |
2007-03-28 |
默克公司 |
作为11-β-羟甾类脱氢酶-1抑制剂的二芳基三唑
|
US20080125403A1
(en)
|
2004-04-02 |
2008-05-29 |
Merck & Co., Inc. |
Method of Treating Men with Metabolic and Anthropometric Disorders
|
JP2008501714A
(ja)
*
|
2004-06-04 |
2008-01-24 |
武田薬品工業株式会社 |
ジペプチジルペプチダーゼインヒビター
|
WO2006019965A2
(en)
|
2004-07-16 |
2006-02-23 |
Takeda San Diego, Inc. |
Dipeptidyl peptidase inhibitors
|
ATE472531T1
(de)
|
2004-08-06 |
2010-07-15 |
Merck Sharp & Dohme |
Sulfonylverbindungen als hemmer von 11-beta- hydroxysteroiddehydrogenase-1
|
AR050615A1
(es)
|
2004-08-27 |
2006-11-08 |
Novartis Ag |
Composiciones farmaceuticas para la administracion oral
|
AU2005289808B2
(en)
*
|
2004-09-24 |
2011-11-03 |
The Government Of The United States As Represented By The Secretary Of The Army, U.S. Army Medical Research Institute Of Chemical Defense |
Method of treating organophosphorous poisoning
|
US9132135B2
(en)
*
|
2004-09-24 |
2015-09-15 |
University Of Maryland, Baltimore |
Method of treating organophosphorous poisoning
|
DE102004054054A1
(de)
|
2004-11-05 |
2006-05-11 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
|
WO2006068978A2
(en)
*
|
2004-12-21 |
2006-06-29 |
Takeda Pharmaceutial Company Limited |
Dipeptidyl peptidase inhibitors
|
DOP2006000008A
(es)
|
2005-01-10 |
2006-08-31 |
Arena Pharm Inc |
Terapia combinada para el tratamiento de la diabetes y afecciones relacionadas y para el tratamiento de afecciones que mejoran mediante un incremento de la concentración sanguínea de glp-1
|
NZ561489A
(en)
|
2005-02-18 |
2010-10-29 |
Mitsubishi Tanabe Pharma Corp |
Salt of proline derivative, solvate thereof, and production method thereof
|
ZA200708179B
(en)
|
2005-04-22 |
2009-12-30 |
Alantos Pharmaceuticals Holding Inc |
Dipeptidyl peptidase-IV inhibitors
|
ES2355156T3
(es)
*
|
2005-04-26 |
2011-03-23 |
Mitsubishi Tanabe Pharma Corporation |
Agente profiláctico/terapéutico para las anomalías del metabolismo lipídico.
|
RU2417985C2
(ru)
|
2005-05-30 |
2011-05-10 |
Баниу Фармасьютикал Ко., Лтд. |
Новые производные пиперидина
|
CA2610022A1
(en)
|
2005-06-06 |
2006-12-14 |
Georgetown University |
Compositions and methods for lipo modeling
|
MY152185A
(en)
|
2005-06-10 |
2014-08-29 |
Novartis Ag |
Modified release 1-[(3-hydroxy-adamant-1-ylamino)-acetyl]-pyrrolidine-2(s)-carbonitrile formulation
|
US20100216758A1
(en)
|
2005-08-10 |
2010-08-26 |
Makoto Ando |
Pyridone Compounds
|
JP2009504599A
(ja)
*
|
2005-08-11 |
2009-02-05 |
エフ.ホフマン−ラ ロシュ アーゲー |
Dpp−iv阻害剤を含有する医薬組成物
|
JPWO2007024004A1
(ja)
|
2005-08-24 |
2009-03-05 |
萬有製薬株式会社 |
フェニルピリドン誘導体
|
EP1939194A4
(en)
|
2005-09-07 |
2010-12-08 |
Banyu Pharma Co Ltd |
AROMATIC SUBSTITUTED BICYLIC PYRIDONE DERIVATIVE
|
DK1942898T4
(da)
*
|
2005-09-14 |
2014-06-02 |
Takeda Pharmaceutical |
Dipeptidylpeptidase-inhibitorer til behandling af diabetes
|
MY159522A
(en)
*
|
2005-09-14 |
2017-01-13 |
Takeda Pharmaceuticals Co |
Administration of dipeptidyl peptidase inhibitors
|
TW200745080A
(en)
*
|
2005-09-16 |
2007-12-16 |
Takeda Pharmaceuticals Co |
Polymorphs of tartrate salt of 2-[2-(3-(R)-amino-piperidin-1-yl)-5-fluoro-6-oxo-6H-pyrimidin-1-ylmethyl]-benzonitrile and methods of use therefor
|
TW200745079A
(en)
*
|
2005-09-16 |
2007-12-16 |
Takeda Pharmaceuticals Co |
Polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile and methods of use therefor
|
KR101368988B1
(ko)
*
|
2005-09-16 |
2014-02-28 |
다케다 야쿠힌 고교 가부시키가이샤 |
디펩티딜 펩티다제 억제제
|
EP1940842B1
(en)
|
2005-09-29 |
2012-05-30 |
Merck Sharp & Dohme Corp. |
Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators
|
CA2627139A1
(en)
|
2005-10-27 |
2007-05-03 |
Banyu Pharmaceutical Co., Ltd. |
Novel benzoxathiin derivative
|
EP1953165B1
(en)
|
2005-11-10 |
2012-02-01 |
Msd K.K. |
Aza-substituted spiro derivative
|
US9101160B2
(en)
|
2005-11-23 |
2015-08-11 |
The Coca-Cola Company |
Condiments with high-potency sweetener
|
EP1801098A1
(en)
|
2005-12-16 |
2007-06-27 |
Merck Sante |
2-Adamantylurea derivatives as selective 11B-HSD1 inhibitors
|
GB0526291D0
(en)
|
2005-12-23 |
2006-02-01 |
Prosidion Ltd |
Therapeutic method
|
CA2645154C
(en)
*
|
2006-03-08 |
2011-11-29 |
Kyorin Pharmaceutical Co., Ltd. |
Method for producing aminoacetylpyrrolidinecarbonitrile derivative and production intermediate thereof
|
JP2009531456A
(ja)
*
|
2006-03-28 |
2009-09-03 |
武田薬品工業株式会社 |
(r)−3−アミノピペリジン二塩酸塩の調製
|
WO2007112347A1
(en)
|
2006-03-28 |
2007-10-04 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
PE20071221A1
(es)
|
2006-04-11 |
2007-12-14 |
Arena Pharm Inc |
Agonistas del receptor gpr119 en metodos para aumentar la masa osea y para tratar la osteoporosis y otras afecciones caracterizadas por masa osea baja, y la terapia combinada relacionada a estos agonistas
|
EP1852108A1
(en)
|
2006-05-04 |
2007-11-07 |
Boehringer Ingelheim Pharma GmbH & Co.KG |
DPP IV inhibitor formulations
|
PE20110235A1
(es)
|
2006-05-04 |
2011-04-14 |
Boehringer Ingelheim Int |
Combinaciones farmaceuticas que comprenden linagliptina y metmorfina
|
CA2810839A1
(en)
|
2006-05-04 |
2007-11-15 |
Boehringer Ingelheim International Gmbh |
A polymorphic form of 1-[(4-methyl-quinazolin-2-yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-(3-(r)-amino-piperidin-1-yl)-xanthine
|
US8324383B2
(en)
|
2006-09-13 |
2012-12-04 |
Takeda Pharmaceutical Company Limited |
Methods of making polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile
|
EP2083831B1
(en)
|
2006-09-22 |
2013-12-25 |
Merck Sharp & Dohme Corp. |
Method of treatment using fatty acid synthesis inhibitors
|
CA2664358A1
(en)
|
2006-09-28 |
2008-04-03 |
Banyu Pharmaceutical Co., Ltd. |
Diarylketimine derivative
|
US8017168B2
(en)
|
2006-11-02 |
2011-09-13 |
The Coca-Cola Company |
High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith
|
TW200838536A
(en)
*
|
2006-11-29 |
2008-10-01 |
Takeda Pharmaceutical |
Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor
|
EP1935420A1
(en)
|
2006-12-21 |
2008-06-25 |
Merck Sante |
2-Adamantyl-butyramide derivatives as selective 11beta-HSD1 inhibitors
|
CN101583601B
(zh)
*
|
2007-01-17 |
2013-06-05 |
香港科技大学 |
作为褪黑素受体mt1和mt2的亚型选择性激动剂的异喹诺酮化合物
|
CA2676066C
(en)
|
2007-01-22 |
2016-06-28 |
Gtx, Inc. |
Nuclear receptor binding agents
|
US9604931B2
(en)
|
2007-01-22 |
2017-03-28 |
Gtx, Inc. |
Nuclear receptor binding agents
|
US9623021B2
(en)
|
2007-01-22 |
2017-04-18 |
Gtx, Inc. |
Nuclear receptor binding agents
|
US8093236B2
(en)
|
2007-03-13 |
2012-01-10 |
Takeda Pharmaceuticals Company Limited |
Weekly administration of dipeptidyl peptidase inhibitors
|
JPWO2008114857A1
(ja)
*
|
2007-03-22 |
2010-07-08 |
杏林製薬株式会社 |
アミノアセチルピロリジンカルボニトリル誘導体の製造方法
|
EP2145884B1
(en)
|
2007-04-02 |
2014-08-06 |
Msd K.K. |
Indoledione derivative
|
JP2010526807A
(ja)
|
2007-05-07 |
2010-08-05 |
メルク・シャープ・エンド・ドーム・コーポレイション |
抗糖尿病活性を有する縮合芳香族化合物を用いた治療法
|
EA020466B1
(ru)
|
2007-06-04 |
2014-11-28 |
Синерджи Фармасьютикалз Инк. |
Агонисты гуанилатциклазы, пригодные для лечения желудочно-кишечных нарушений, воспаления, рака и других заболеваний
|
US8969514B2
(en)
|
2007-06-04 |
2015-03-03 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
|
WO2009110510A1
(ja)
|
2008-03-06 |
2009-09-11 |
萬有製薬株式会社 |
アルキルアミノピリジン誘導体
|
JPWO2009119726A1
(ja)
|
2008-03-28 |
2011-07-28 |
Msd株式会社 |
メラニン凝集ホルモン受容体拮抗作用を有するジアリールメチルアミド誘導体
|
PE20091730A1
(es)
|
2008-04-03 |
2009-12-10 |
Boehringer Ingelheim Int |
Formulaciones que comprenden un inhibidor de dpp4
|
EP2108960A1
(en)
|
2008-04-07 |
2009-10-14 |
Arena Pharmaceuticals, Inc. |
Methods of using A G protein-coupled receptor to identify peptide YY (PYY) secretagogues and compounds useful in the treatment of conditons modulated by PYY
|
EP2110374A1
(en)
|
2008-04-18 |
2009-10-21 |
Merck Sante |
Benzofurane, benzothiophene, benzothiazol derivatives as FXR modulators
|
CA2726917C
(en)
|
2008-06-04 |
2018-06-26 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
|
AU2009261248A1
(en)
|
2008-06-19 |
2009-12-23 |
Banyu Pharmaceutical Co., Ltd. |
Spirodiamine-diarylketoxime derivative
|
CA2730603C
(en)
|
2008-07-16 |
2019-09-24 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
|
JPWO2010013595A1
(ja)
|
2008-07-30 |
2012-01-12 |
Msd株式会社 |
5員−5員又は5員−6員縮環シクロアルキルアミン誘導体
|
BRPI0916997A2
(pt)
|
2008-08-06 |
2020-12-15 |
Boehringer Ingelheim International Gmbh |
Inibidor de dpp-4 e seu uso
|
CN102119139A
(zh)
*
|
2008-08-07 |
2011-07-06 |
杏林制药株式会社 |
二环[2.2.2]辛胺衍生物的制造方法
|
KR20110044780A
(ko)
*
|
2008-08-14 |
2011-04-29 |
교린 세이야꾸 가부시키 가이샤 |
안정화된 의약 조성물
|
US20200155558A1
(en)
|
2018-11-20 |
2020-05-21 |
Boehringer Ingelheim International Gmbh |
Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
|
CN102264228A
(zh)
|
2008-10-22 |
2011-11-30 |
默沙东公司 |
用于抗糖尿病药的新的环状苯并咪唑衍生物
|
JP5635991B2
(ja)
|
2008-10-30 |
2014-12-03 |
メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. |
イソニコチンアミドオレキシン受容体アンタゴニスト
|
US8329914B2
(en)
|
2008-10-31 |
2012-12-11 |
Merck Sharp & Dohme Corp |
Cyclic benzimidazole derivatives useful as anti-diabetic agents
|
EP2344519B1
(en)
|
2008-11-07 |
2016-09-28 |
The General Hospital Corporation |
C-terminal fragments of glucagon-like peptide-1 (glp-1)
|
US8759539B2
(en)
|
2008-11-17 |
2014-06-24 |
Merck Sharp & Dohme Corp. |
Substituted bicyclic amines for the treatment of diabetes
|
AR077642A1
(es)
|
2009-07-09 |
2011-09-14 |
Arena Pharm Inc |
Moduladores del metabolismo y el tratamiento de trastornos relacionados con el mismo
|
US20120220567A1
(en)
|
2009-07-23 |
2012-08-30 |
Shipps Jr Gerald W |
Benzo-fused oxazepine compounds as stearoyl-coenzyme a delta-9 desaturase inhibitors
|
WO2011011506A1
(en)
|
2009-07-23 |
2011-01-27 |
Schering Corporation |
Spirocyclic oxazepine compounds as stearoyl-coenzyme a delta-9 desaturase inhibitors
|
JP2013510834A
(ja)
|
2009-11-16 |
2013-03-28 |
メリテク |
[1,5]‐ジアゾシン誘導体
|
CN107115530A
(zh)
|
2009-11-27 |
2017-09-01 |
勃林格殷格翰国际有限公司 |
基因型糖尿病患者利用dpp‑iv抑制剂例如利拉利汀的治疗
|
CN103664873B
(zh)
|
2009-12-30 |
2016-06-15 |
深圳信立泰药业股份有限公司 |
作为二肽基肽酶iv(dpp-iv)抑制剂的3-(3-氨基哌啶-1-基)-5-氧代-1,2,4-三嗪衍生物
|
WO2011106273A1
(en)
|
2010-02-25 |
2011-09-01 |
Merck Sharp & Dohme Corp. |
Novel cyclic benzimidazole derivatives useful anti-diabetic agents
|
AU2011237775A1
(en)
|
2010-04-06 |
2012-11-22 |
Arena Pharmaceuticals, Inc. |
Modulators of the GPR119 receptor and the treatment of disorders related thereto
|
KR101927068B1
(ko)
|
2010-05-05 |
2018-12-10 |
베링거 인겔하임 인터내셔날 게엠베하 |
체중 감소 치료에 후속하는 dpp-4 억제제에 의한 순차적 병용 요법
|
US20130156720A1
(en)
|
2010-08-27 |
2013-06-20 |
Ironwood Pharmaceuticals, Inc. |
Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
|
US9616097B2
(en)
|
2010-09-15 |
2017-04-11 |
Synergy Pharmaceuticals, Inc. |
Formulations of guanylate cyclase C agonists and methods of use
|
CN103539791B
(zh)
|
2010-09-22 |
2017-01-11 |
艾尼纳制药公司 |
Gpr119 受体调节剂和对与其相关的障碍的治疗
|
WO2012061466A2
(en)
|
2010-11-02 |
2012-05-10 |
The General Hospital Corporation |
Methods for treating steatotic disease
|
US9034883B2
(en)
|
2010-11-15 |
2015-05-19 |
Boehringer Ingelheim International Gmbh |
Vasoprotective and cardioprotective antidiabetic therapy
|
CA2826649C
(en)
|
2011-02-25 |
2016-07-26 |
Merck Sharp & Dohme Corp. |
Novel cyclic azabenzimidazole derivatives useful as anti-diabetic agents
|
WO2012118972A2
(en)
|
2011-03-01 |
2012-09-07 |
Synegy Pharmaceuticals Inc. |
Process of preparing guanylate cyclase c agonists
|
CN102190641A
(zh)
*
|
2011-03-23 |
2011-09-21 |
四川科伦药物研究有限公司 |
一种制备西酞普兰和艾司西酞普兰关键中间体的方法
|
US20140018371A1
(en)
|
2011-04-01 |
2014-01-16 |
Arena Pharmaceuticals, Inc. |
Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto
|
WO2012145361A1
(en)
|
2011-04-19 |
2012-10-26 |
Arena Pharmaceuticals, Inc. |
Modulators of the gpr119 receptor and the treatment of disorders related thereto
|
US20140038889A1
(en)
|
2011-04-22 |
2014-02-06 |
Arena Pharmaceuticals, Inc. |
Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto
|
WO2012145604A1
(en)
|
2011-04-22 |
2012-10-26 |
Arena Pharmaceuticals, Inc. |
Modulators of the gpr119 receptor and the treatment of disorders related thereto
|
WO2012170702A1
(en)
|
2011-06-08 |
2012-12-13 |
Arena Pharmaceuticals, Inc. |
Modulators of the gpr119 receptor and the treatment of disorders related thereto
|
WO2013006692A2
(en)
|
2011-07-06 |
2013-01-10 |
The General Hospital Corporation |
Methods of treatment using a pentapeptide derived from the c-terminus of glucagon-like peptide 1 (glp-1)
|
WO2013055910A1
(en)
|
2011-10-12 |
2013-04-18 |
Arena Pharmaceuticals, Inc. |
Modulators of the gpr119 receptor and the treatment of disorders related thereto
|
AR088352A1
(es)
|
2011-10-19 |
2014-05-28 |
Merck Sharp & Dohme |
Antagonistas del receptor de 2-piridiloxi-4-nitrilo orexina
|
US9555001B2
(en)
|
2012-03-07 |
2017-01-31 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition and uses thereof
|
US20130303462A1
(en)
|
2012-05-14 |
2013-11-14 |
Boehringer Ingelheim International Gmbh |
Use of a dpp-4 inhibitor in podocytes related disorders and/or nephrotic syndrome
|
WO2013174767A1
(en)
|
2012-05-24 |
2013-11-28 |
Boehringer Ingelheim International Gmbh |
A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
|
US20140045746A1
(en)
|
2012-08-02 |
2014-02-13 |
Merck Sharp & Dohme Corp. |
Antidiabetic tricyclic compounds
|
WO2014074668A1
(en)
|
2012-11-08 |
2014-05-15 |
Arena Pharmaceuticals, Inc. |
Modulators of gpr119 and the treatment of disorders related thereto
|
BR112015019836A2
(pt)
|
2013-02-22 |
2017-07-18 |
Merck Sharp & Dohme |
composto, composição farmacêutica, e, uso de um composto
|
US9650375B2
(en)
|
2013-03-14 |
2017-05-16 |
Merck Sharp & Dohme Corp. |
Indole derivatives useful as anti-diabetic agents
|
CA2905435A1
(en)
|
2013-03-15 |
2014-09-25 |
Synergy Pharmaceuticals Inc. |
Compositions useful for the treatment of gastrointestinal disorders
|
EP2970384A1
(en)
|
2013-03-15 |
2016-01-20 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase and their uses
|
CN113388007A
(zh)
|
2013-06-05 |
2021-09-14 |
博士医疗爱尔兰有限公司 |
鸟苷酸环化酶c的超纯激动剂、制备和使用所述激动剂的方法
|
WO2015051496A1
(en)
|
2013-10-08 |
2015-04-16 |
Merck Sharp & Dohme Corp. |
Antidiabetic tricyclic compounds
|
JP6615109B2
(ja)
|
2014-02-28 |
2019-12-04 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Dpp−4阻害薬の医学的使用
|
EP3186242B1
(en)
|
2014-08-29 |
2021-10-06 |
Tes Pharma S.r.l. |
Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase
|
AU2016229982B2
(en)
|
2015-03-09 |
2020-06-18 |
Intekrin Therapeutics, Inc. |
Methods for the treatment of nonalcoholic fatty liver disease and/or lipodystrophy
|
EP3317277B1
(en)
|
2015-07-01 |
2021-01-20 |
Crinetics Pharmaceuticals, Inc. |
Somatostatin modulators and uses thereof
|
CA3022202A1
(en)
|
2016-06-10 |
2017-12-14 |
Boehringer Ingelheim International Gmbh |
Combinations of linagliptin and metformin
|
EP3526199B1
(en)
|
2016-10-14 |
2022-04-13 |
Tes Pharma S.r.l. |
Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase
|
US11072602B2
(en)
|
2016-12-06 |
2021-07-27 |
Merck Sharp & Dohme Corp. |
Antidiabetic heterocyclic compounds
|
EP3558298A4
(en)
|
2016-12-20 |
2020-08-05 |
Merck Sharp & Dohme Corp. |
ANTIDIABETIC SPIROCHROMAN COMPOUNDS
|
WO2018162722A1
(en)
|
2017-03-09 |
2018-09-13 |
Deutsches Institut Für Ernährungsforschung Potsdam-Rehbrücke |
Dpp-4 inhibitors for use in treating bone fractures
|
BR112019020485A2
(pt)
|
2017-04-03 |
2020-05-12 |
Coherus Biosciences, Inc. |
Agonista ppary para tratamento de paralisia supranuclear progressiva
|
US11028068B2
(en)
|
2017-07-25 |
2021-06-08 |
Crinetics Pharmaceuticals, Inc. |
Somatostatin modulators and uses thereof
|
CN113302189A
(zh)
|
2018-11-20 |
2021-08-24 |
Tes制药有限责任公司 |
α-氨基-β-羧基己二烯二酸半醛去羧酶的抑制剂
|
EP3924058A1
(en)
|
2019-02-13 |
2021-12-22 |
Merck Sharp & Dohme Corp. |
5-alkyl pyrrolidine orexin receptor agonists
|
EP4010314B1
(en)
|
2019-08-08 |
2024-02-28 |
Merck Sharp & Dohme LLC |
Heteroaryl pyrrolidine and piperidine orexin receptor agonists
|
JP7443625B2
(ja)
|
2020-08-18 |
2024-03-05 |
メルク・シャープ・アンド・ドーム・エルエルシー |
ビシクロヘプタンピロリジンオレキシン受容体アゴニスト
|