HUP0303431A2 - PRRS vírus élő legyengített törzsei - Google Patents

PRRS vírus élő legyengített törzsei

Info

Publication number
HUP0303431A2
HUP0303431A2 HU0303431A HUP0303431A HUP0303431A2 HU P0303431 A2 HUP0303431 A2 HU P0303431A2 HU 0303431 A HU0303431 A HU 0303431A HU P0303431 A HUP0303431 A HU P0303431A HU P0303431 A2 HUP0303431 A2 HU P0303431A2
Authority
HU
Hungary
Prior art keywords
viruses
prrs
live attenuated
prrs virus
attenuated strains
Prior art date
Application number
HU0303431A
Other languages
English (en)
Hungarian (hu)
Inventor
Knut Elbers
Stefan Peschke
Bettina Schuetz
Original Assignee
Boehringer Ingelheim Vetmedica Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Vetmedica Gmbh filed Critical Boehringer Ingelheim Vetmedica Gmbh
Publication of HUP0303431A2 publication Critical patent/HUP0303431A2/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04Inactivation or attenuation; Producing viral sub-units
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/10011Arteriviridae
    • C12N2770/10021Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/10011Arteriviridae
    • C12N2770/10022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/10011Arteriviridae
    • C12N2770/10061Methods of inactivation or attenuation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/10011Arteriviridae
    • C12N2770/10061Methods of inactivation or attenuation
    • C12N2770/10062Methods of inactivation or attenuation by genetic engineering

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
HU0303431A 2001-03-09 2002-03-07 PRRS vírus élő legyengített törzsei HUP0303431A2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27460301P 2001-03-09 2001-03-09
PCT/EP2002/002486 WO2002072802A2 (en) 2001-03-09 2002-03-07 Live attenuated strains of prrs virus

Publications (1)

Publication Number Publication Date
HUP0303431A2 true HUP0303431A2 (hu) 2004-01-28

Family

ID=23048885

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0303431A HUP0303431A2 (hu) 2001-03-09 2002-03-07 PRRS vírus élő legyengített törzsei

Country Status (12)

Country Link
EP (1) EP1421184A2 (cs)
JP (1) JP2004534522A (cs)
KR (1) KR20030082960A (cs)
BR (1) BR0207988A (cs)
CA (1) CA2439254A1 (cs)
CZ (1) CZ20032743A3 (cs)
HU (1) HUP0303431A2 (cs)
MX (1) MXPA03007751A (cs)
PL (1) PL370541A1 (cs)
RU (1) RU2003129068A (cs)
SK (1) SK11282003A3 (cs)
WO (1) WO2002072802A2 (cs)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1438969A1 (en) * 2003-01-14 2004-07-21 Universiteit Utrecht Arterivirus marker vaccine
KR20050040172A (ko) * 2003-10-27 2005-05-03 주식회사 중앙백신연구소 돼지 생식기호흡기 증후군 바이러스 불활화 백신의 제조방법
AU2005306781B2 (en) * 2004-11-19 2011-12-22 Intervet International B.V. Porcine reproductive and respiratory syndrome virus strains and compositions
EP1856141A1 (en) * 2005-02-25 2007-11-21 Pfizer Products Inc. N protein mutants of porcine reproductive and respiratory syndrome virus
WO2009008924A2 (en) 2007-04-05 2009-01-15 Mount Sinai School Of Medicine Of New York University Methods of preventing and treating viral infections by inhibiting the deisgylation activity of otu domain-containing viral proteins
CN101454442A (zh) * 2007-06-15 2009-06-10 普泰克国际有限公司 嵌合体prrsv的构建,组合物及疫苗的制备
US7666585B2 (en) 2007-06-15 2010-02-23 Protatek International, Inc. Construction of chimera PRRSV, compositions and vaccine preparations
ES2550258T3 (es) * 2011-02-17 2015-11-05 Boehringer Ingelheim Vetmedica Gmbh Nueva cepa del PRRSV europea
KR101420850B1 (ko) * 2011-05-30 2014-08-13 건국대학교 산학협력단 돼지 생식기 호흡기 증후군 바이러스 유사입자 및 이를 이용한 백신
KR101281361B1 (ko) * 2011-07-18 2013-07-02 서울대학교산학협력단 북미형 돼지 생식기 호흡기 증후군 바이러스 예방 백신 조성물 및 이를 포함하는 혼합백신 조성물
KR101245029B1 (ko) * 2012-01-18 2013-03-18 서울대학교산학협력단 한국형 돼지 생식기 호흡기 증후군 바이러스 예방 백신 조성물
WO2013173443A1 (en) * 2012-05-17 2013-11-21 Zoetis Llc Effective vaccination against porcine reproductive and respiratory syndrome (prrs) virus prior to weaning
CN103290142B (zh) * 2013-03-29 2015-03-11 云南农业大学 荧光定量rt-pcr检测猪蓝耳病弱毒疫苗病毒含量的方法
KR101624485B1 (ko) 2014-08-13 2016-05-26 전북대학교산학협력단 돼지생식기호흡기증후군 바이러스(prrsv) 변이주 및 이를 포함하는 돼지 생식기 호흡기 증후군 예방 또는 치료용 백신 조성물
CN104694561B (zh) * 2015-02-10 2018-02-23 中国农业科学院上海兽医研究所 表达海肾或萤火虫荧光素酶基因的prrsv重组质粒的构建方法以及应用
AU2019463018A1 (en) * 2019-08-29 2022-02-03 Elanco Uk Ah Limited Porcine reproductive and respiratory syndrome vaccine virus
KR102276341B1 (ko) * 2020-01-29 2021-07-12 주식회사 바이오포아 유럽형 돼지 생식기 호흡기 증후군 바이러스의 제조 방법 및 이의 용도
EP4098741A4 (en) * 2020-01-29 2024-04-03 Biopoa, Inc. MUTANT STRAIN OF EUROPEAN SWINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS, AND VACCINE USING SAME

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2290906C (en) * 1991-06-06 2003-04-01 Stichting Centraal Diergeneeskundig Instituut Causative agent of the mystery swine disease, vaccine compositions and diagnostic kits
US6592873B1 (en) * 1992-10-30 2003-07-15 Iowa State University Research Foundation, Inc. Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids
CN1259141B (zh) * 1997-05-06 2013-03-27 勃林格殷格汉动物保健有限公司 用于疫苗或诊断测试中的鉴定prrs病毒的肽序列的prrsv抗原位点
WO1998055626A2 (en) * 1997-06-05 1998-12-10 Origen, Inc. Recombinant porcine reproductive and respiratory syndrome virus (prrsv) for use as a vaccine
EP1157121B1 (en) * 1999-03-08 2013-04-24 Boehringer Ingelheim Vetmedica GmbH Prrsv replicon
WO2002095040A1 (en) * 2001-05-21 2002-11-28 Id-Lelystad, Instituut Voor Dierhouderij En Diergezondheid B.V. Delections in arterivirus replicons
BR0107827A (pt) * 2000-01-26 2002-11-05 Boehringer Ingelheim Vetmed Atenuação recombinante de prrsv
EP1156111A1 (en) * 2000-05-19 2001-11-21 Stichting Dienst Landbouwkundig Onderzoek Chimeric arterivirus-like particles
MXPA02011545A (es) * 2000-05-24 2003-06-06 Merial Sas Virus del sindrome respiratorio y reproductor porcino (peesv), vacuna recombinante para el virus de la viruela.

Also Published As

Publication number Publication date
CA2439254A1 (en) 2002-09-19
PL370541A1 (en) 2005-05-30
WO2002072802A2 (en) 2002-09-19
CZ20032743A3 (cs) 2004-02-18
JP2004534522A (ja) 2004-11-18
SK11282003A3 (sk) 2004-02-03
EP1421184A2 (en) 2004-05-26
MXPA03007751A (es) 2004-11-12
KR20030082960A (ko) 2003-10-23
WO2002072802A3 (en) 2004-03-11
RU2003129068A (ru) 2005-04-10
BR0207988A (pt) 2004-10-26

Similar Documents

Publication Publication Date Title
HUP0303431A2 (hu) PRRS vírus élő legyengített törzsei
HUP0303720A2 (hu) Egy immunstimuláns oligonukleotidot és egy tokolt tartalmazó adjuvánskészítmény
CY1106334T1 (el) Βελτιστοποιημενου κωδικονιου αλληλουχιες ιου θηλωματος
EA200501890A1 (ru) Вирусы гриппа высокого титра для приготовления вакцин и генной терапии
NL300899I2 (nl) Neisseira meningitidis serogroep B recombinant gelipideerd fHbp subfamilie A05 eiwit en Neisseira meningitidis serogroep B recombinant gelipideerd fHbp subfamilie B01 eiwit
HUP0102304A1 (hu) B Csoportba tartozó Streptococcus antigének
MXPA01011047A (es) Secuencias genomicas de neisseria y metodos para su uso.
EE200200507A (et) Muundatud vaktsiiniaviirus Ankara (MVA), sellega nakatatud peremeesrakk ning seda sisaldav farmatseutiline kompositsioon, MVA valmistamine ja raviotstarbeline kasutamine
CY1113379T1 (el) Πεπτιδια κdr και εμβολια που τα περιλαμβανουν
NZ543467A (en) The severe acute respiratory syndrome coronavirus
RS51699B (sr) Beta-amiloid-analog-t-ćelijski-epitop vakcina
MXPA05011110A (es) Composiciones inmunogenicas novedosas para la prevencion y tratamiento de un padecimiento originado por meningococos.
CY1113875T1 (el) Βελτιστοποιημενη εκφραση hpv 58 l1 σε ζυμομυκητα
AU2002248384A1 (en) Serpin drugs for treatment of hiv infection and method of use thereof
NO20060931L (no) Trygge mutante virusvaksiner
HUP0402259A2 (hu) Vakcinák
DK0495896T3 (da) Vaccine til beskyttelse mod HIV-virusinfektioner, fremgangsmåde til fremstilling heraf og anvendelse heraf som diagnostisk middel og immunterapeutisk middel
TW200502246A (en) Vaccine
HUP0203335A1 (hu) Vakcina
HUP0302612A2 (hu) Salmonella vakcina
FR21C1005I2 (fr) Antigenes de streptococcus pyogenes et fragments d'adn correspondants
AU2014232363A8 (en) Foot and mouth disease virus (FMDV) consensus proteins, coding sequences therefor and vaccines made therefrom
DK1425404T3 (da) Vaccinia-MVA-E3L-mutanter og anvendelse deraf
JP2006512078A5 (cs)
ATE355069T1 (de) Verfahren zur herstellung polyvalenter bakteriophagenpräparationen zur behandlung bakterieller infektionen