HUP0303431A2 - PRRS vírus élő legyengített törzsei - Google Patents

PRRS vírus élő legyengített törzsei

Info

Publication number
HUP0303431A2
HUP0303431A2 HU0303431A HUP0303431A HUP0303431A2 HU P0303431 A2 HUP0303431 A2 HU P0303431A2 HU 0303431 A HU0303431 A HU 0303431A HU P0303431 A HUP0303431 A HU P0303431A HU P0303431 A2 HUP0303431 A2 HU P0303431A2
Authority
HU
Hungary
Prior art keywords
viruses
prrs
live attenuated
prrs virus
attenuated strains
Prior art date
Application number
HU0303431A
Other languages
English (en)
Hungarian (hu)
Inventor
Knut Elbers
Stefan Peschke
Bettina Schuetz
Original Assignee
Boehringer Ingelheim Vetmedica Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Vetmedica Gmbh filed Critical Boehringer Ingelheim Vetmedica Gmbh
Publication of HUP0303431A2 publication Critical patent/HUP0303431A2/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04Inactivation or attenuation; Producing viral sub-units
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/10011Arteriviridae
    • C12N2770/10021Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/10011Arteriviridae
    • C12N2770/10022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/10011Arteriviridae
    • C12N2770/10061Methods of inactivation or attenuation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/10011Arteriviridae
    • C12N2770/10061Methods of inactivation or attenuation
    • C12N2770/10062Methods of inactivation or attenuation by genetic engineering

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
HU0303431A 2001-03-09 2002-03-07 PRRS vírus élő legyengített törzsei HUP0303431A2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27460301P 2001-03-09 2001-03-09
PCT/EP2002/002486 WO2002072802A2 (en) 2001-03-09 2002-03-07 Live attenuated strains of prrs virus

Publications (1)

Publication Number Publication Date
HUP0303431A2 true HUP0303431A2 (hu) 2004-01-28

Family

ID=23048885

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0303431A HUP0303431A2 (hu) 2001-03-09 2002-03-07 PRRS vírus élő legyengített törzsei

Country Status (12)

Country Link
EP (1) EP1421184A2 (cs)
JP (1) JP2004534522A (cs)
KR (1) KR20030082960A (cs)
BR (1) BR0207988A (cs)
CA (1) CA2439254A1 (cs)
CZ (1) CZ20032743A3 (cs)
HU (1) HUP0303431A2 (cs)
MX (1) MXPA03007751A (cs)
PL (1) PL370541A1 (cs)
RU (1) RU2003129068A (cs)
SK (1) SK11282003A3 (cs)
WO (1) WO2002072802A2 (cs)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1438969A1 (en) * 2003-01-14 2004-07-21 Universiteit Utrecht Arterivirus marker vaccine
KR20050040172A (ko) * 2003-10-27 2005-05-03 주식회사 중앙백신연구소 돼지 생식기호흡기 증후군 바이러스 불활화 백신의 제조방법
MX2007005968A (es) * 2004-11-19 2007-07-20 Intervet Int Bv Cepas y composiciones del virus del sindrome reproductivo y respiratorio porcino.
RU2381035C2 (ru) * 2005-02-25 2010-02-10 Пфайзер Продактс Инк. Композиция для защиты свиней от инфекции ррсс-вируса (варианты) и вакцина, содержащая указанную композицию (варианты)
US8709730B2 (en) 2007-04-05 2014-04-29 Icahn School Of Medicine At Mount Sinai Methods of preventing and treating viral infections by inhibiting the deISGylation activity of OTU domain-containing viral proteins
WO2008153572A1 (en) * 2007-06-15 2008-12-18 Protatek International, Inc. Construction of chimera prrsv, compositions and vaccine preparations
US7666585B2 (en) 2007-06-15 2010-02-23 Protatek International, Inc. Construction of chimera PRRSV, compositions and vaccine preparations
US8765142B2 (en) * 2011-02-17 2014-07-01 Boehringer Ingelheim Vetmedica Gmbh European PRRSV strain
KR101420850B1 (ko) * 2011-05-30 2014-08-13 건국대학교 산학협력단 돼지 생식기 호흡기 증후군 바이러스 유사입자 및 이를 이용한 백신
KR101281361B1 (ko) * 2011-07-18 2013-07-02 서울대학교산학협력단 북미형 돼지 생식기 호흡기 증후군 바이러스 예방 백신 조성물 및 이를 포함하는 혼합백신 조성물
KR101245029B1 (ko) * 2012-01-18 2013-03-18 서울대학교산학협력단 한국형 돼지 생식기 호흡기 증후군 바이러스 예방 백신 조성물
KR102012109B1 (ko) * 2012-05-17 2019-08-19 조에티스 엘엘씨 이유 전 돼지 생식기 호흡기 증후군(prrs) 바이러스에 대한 효과적인 백신접종
CN103290142B (zh) * 2013-03-29 2015-03-11 云南农业大学 荧光定量rt-pcr检测猪蓝耳病弱毒疫苗病毒含量的方法
KR101624485B1 (ko) 2014-08-13 2016-05-26 전북대학교산학협력단 돼지생식기호흡기증후군 바이러스(prrsv) 변이주 및 이를 포함하는 돼지 생식기 호흡기 증후군 예방 또는 치료용 백신 조성물
CN104694561B (zh) * 2015-02-10 2018-02-23 中国农业科学院上海兽医研究所 表达海肾或萤火虫荧光素酶基因的prrsv重组质粒的构建方法以及应用
WO2021037387A1 (en) * 2019-08-29 2021-03-04 Elanco Us Inc. Porcine reproductive and respiratory syndrome vaccine virus
EP4098741A4 (en) * 2020-01-29 2024-04-03 Biopoa, Inc. MUTANT STRAIN OF EUROPEAN SWINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS, AND VACCINE USING SAME
KR102276341B1 (ko) * 2020-01-29 2021-07-12 주식회사 바이오포아 유럽형 돼지 생식기 호흡기 증후군 바이러스의 제조 방법 및 이의 용도

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX9202724A (es) * 1991-06-06 1992-12-31 Stichting Centr Diergeneeskund Composicion que comprende un vector recombinante del agente lelystad y vacuna que comprende la misma.
US6592873B1 (en) * 1992-10-30 2003-07-15 Iowa State University Research Foundation, Inc. Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids
CZ297371B6 (cs) * 1997-05-06 2006-11-15 Boehringer Ingelheim Vetmedica Gmbh Peptid mající 5 az 15 aminokyselinových zbytku vyvolávající tvorbu protilátek, protilátka reaktivnís tímto peptidem a diagnostická testovací souprava
AU7960598A (en) * 1997-06-05 1998-12-21 Origen, Inc. Recombinant porcine reproductive and respiratory syndrome virus (prrsv) for use as a vaccine
JP3961222B2 (ja) * 1999-03-08 2007-08-22 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー Prrsvワクチン
EA200200743A1 (ru) * 2000-01-26 2002-12-26 Бёрингер Ингельхайм Ветмедика Кг Рекомбинантное ослабление вируса репродуктивного и респираторного синдрома свиней (prrsv)
EP1156111A1 (en) * 2000-05-19 2001-11-21 Stichting Dienst Landbouwkundig Onderzoek Chimeric arterivirus-like particles
WO2001089559A2 (en) * 2000-05-24 2001-11-29 Merial Porcine reproductive and respiratory syndrome virus (prrsv) recombinant avipoxvirus vaccine
EP1397498A1 (en) * 2001-05-21 2004-03-17 ID-Lelystad, Instituut voor Dierhouderij en Diergezondheid B.V. Delections in arterivirus replicons

Also Published As

Publication number Publication date
MXPA03007751A (es) 2004-11-12
KR20030082960A (ko) 2003-10-23
JP2004534522A (ja) 2004-11-18
CZ20032743A3 (cs) 2004-02-18
RU2003129068A (ru) 2005-04-10
BR0207988A (pt) 2004-10-26
EP1421184A2 (en) 2004-05-26
WO2002072802A3 (en) 2004-03-11
CA2439254A1 (en) 2002-09-19
PL370541A1 (en) 2005-05-30
WO2002072802A2 (en) 2002-09-19
SK11282003A3 (sk) 2004-02-03

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