EA200501890A1 - Вирусы гриппа высокого титра для приготовления вакцин и генной терапии - Google Patents
Вирусы гриппа высокого титра для приготовления вакцин и генной терапииInfo
- Publication number
- EA200501890A1 EA200501890A1 EA200501890A EA200501890A EA200501890A1 EA 200501890 A1 EA200501890 A1 EA 200501890A1 EA 200501890 A EA200501890 A EA 200501890A EA 200501890 A EA200501890 A EA 200501890A EA 200501890 A1 EA200501890 A1 EA 200501890A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- high titer
- gene therapy
- flu viruses
- preparing vaccines
- viruses
- Prior art date
Links
- 241000700605 Viruses Species 0.000 title abstract 2
- 238000001415 gene therapy Methods 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
- 241000712461 unidentified influenza virus Species 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/02—Recovery or purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/08—Clostridium, e.g. Clostridium tetani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/04—Inactivation or attenuation; Producing viral sub-units
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16141—Use of virus, viral particle or viral elements as a vector
- C12N2760/16143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Изобретение относится к композициям, полезным для получения вирусов гриппа в высоких титрах, например, в отсутствие хелперных вирусов, содержащих последовательности генов из изолятов вирусов гриппа высоких титров.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US47379803P | 2003-05-28 | 2003-05-28 | |
PCT/US2004/016680 WO2004112831A2 (en) | 2003-05-28 | 2004-05-27 | High titer recombinant influenza viruses for vaccines and gene therapy |
Publications (2)
Publication Number | Publication Date |
---|---|
EA200501890A1 true EA200501890A1 (ru) | 2006-06-30 |
EA012965B1 EA012965B1 (ru) | 2010-02-26 |
Family
ID=33539054
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA200501890A EA012965B1 (ru) | 2003-05-28 | 2004-05-27 | Композиция для получения реассортантного рекомбинантного вируса гриппа, способ получения указанного вируса и реассортантный рекомбинантный вирус гриппа |
Country Status (19)
Country | Link |
---|---|
US (1) | US8475806B2 (ru) |
EP (1) | EP1631663B1 (ru) |
JP (2) | JP5215561B2 (ru) |
KR (1) | KR100908757B1 (ru) |
CN (1) | CN1826407B (ru) |
AU (1) | AU2004249133B2 (ru) |
BR (1) | BRPI0410702B1 (ru) |
CA (1) | CA2525953C (ru) |
EA (1) | EA012965B1 (ru) |
ES (1) | ES2593082T3 (ru) |
HK (1) | HK1082769A1 (ru) |
HU (1) | HUE030962T2 (ru) |
IL (2) | IL171831A (ru) |
MX (1) | MX342639B (ru) |
NO (1) | NO341506B1 (ru) |
NZ (1) | NZ543446A (ru) |
UA (1) | UA92132C2 (ru) |
WO (1) | WO2004112831A2 (ru) |
ZA (1) | ZA200510309B (ru) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
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US8715940B2 (en) | 1999-04-06 | 2014-05-06 | Wisconsin Alumni Research Foundation | Method of making recombinant influenza virus |
ES2217967B1 (es) * | 2003-03-31 | 2006-01-01 | Consejo Sup. Investig. Cientificas | Procedimiento de produccion de particulas virales vacias (vlps) del virus inductor de la bursitis infecciosa (ibdv), composiciones necesarias para su puesta a punto y su uso en la elaboracion de vacunas frente al ibdv. |
JP5215561B2 (ja) | 2003-05-28 | 2013-06-19 | ウィスコンシン アルムニ リサーチ ファンデイション | ワクチン及び遺伝子治療のための高力価組換えインフルエンザ・ウイルス |
ES2307345B1 (es) * | 2004-01-21 | 2009-11-13 | Consejo Sup. Investig. Cientificas | Capsidas vacias quimericas del virus causante de la enfermedad de la bursitis infecciosa (ibdv), su procedimiento de obtencion y aplicaciones. |
ES2307346B1 (es) * | 2004-01-21 | 2009-11-13 | Consejo Sup. Investig. Cientificas | Capsidas vacias (vlps(-vp4)) del virus causante de la enfermedad de la bursitis infecciosa (ibdv), su procedimiento de obtencion y aplicaciones. |
CA2587510A1 (en) | 2004-11-19 | 2007-04-19 | Wisconsin Alumni Research Foundation | Recombinant influenza vectors with tandem transcription units |
US7572620B2 (en) | 2005-01-11 | 2009-08-11 | Wisconsin Alumni Research Foundation | H3 equine influenza A virus |
EP1917361A4 (en) * | 2005-06-21 | 2009-07-29 | Medimmune Vaccines Inc | METHODS AND COMPOSITIONS FOR EXPRESSING NEGATIVE SENSE RNA VIRUS IN CANINE CELLS |
US7790434B2 (en) * | 2005-06-21 | 2010-09-07 | Medimmune, Llc | Methods and compositions for expressing negative-sense viral RNA in canine cells |
ES2310062B1 (es) * | 2005-07-15 | 2009-11-13 | Bionostra, S.L. | Particulas pseudovirales vacias quimericas derivadas del virus causante de la enfermedad de la bursitis infecciosa (ibdv), procedimiento de obtencion y aplicaciones. |
US7871626B2 (en) | 2005-08-04 | 2011-01-18 | St. Jude Children's Research Hospital | Modified influenza virus for monitoring and improving vaccine efficiency |
ATE494906T1 (de) | 2005-11-01 | 2011-01-15 | Novartis Vaccines & Diagnostic | Von zellen stammende virale impfstoffe mit geringen mengen an rest-zell-dna |
KR101484305B1 (ko) * | 2006-03-10 | 2015-01-19 | 위스콘신 얼럼나이 리서어치 화운데이션 | H3 말 인플루엔자 a 바이러스 |
JP2007259758A (ja) * | 2006-03-28 | 2007-10-11 | Wisconsin Alumni Research Foundation | H3型ウマa型インフルエンザウイルス |
WO2007126810A2 (en) * | 2006-03-31 | 2007-11-08 | Warf - Wisconsin Alumni Research Foundation | High titer recombinant influenza viruses for vaccines |
AU2013204811B2 (en) * | 2006-04-19 | 2015-01-22 | Medimmune, Llc | Methods and compositions for expressing negative-sense viral rna in canine cells |
DK2016194T3 (en) * | 2006-04-19 | 2015-06-15 | Medimmune Llc | METHODS AND COMPOSITIONS FOR EXPRESSION OF VIRAL NEGATIVE SENSE RNA IN DOG CELLS |
US20090017444A1 (en) * | 2006-06-09 | 2009-01-15 | Wisconsin Alumni Research Foundation | Screening method for modulators of viral transcription or replication |
EP2043681B1 (en) | 2006-07-14 | 2015-10-07 | Sanofi Pasteur Biologics, LLC | Construction of recombinant virus vaccines by direct transposon-mediated insertion of foreign immunologic determinants into vector virus proteins |
KR20090096414A (ko) * | 2006-09-29 | 2009-09-10 | 사노피 파스테르 바이오로직스 씨오 | 재조합 리노바이러스 벡터 |
WO2008128176A1 (en) * | 2007-04-12 | 2008-10-23 | Nucleonics, Inc. | Influenza polynucleotides, expression constructs, compositions, and methods of use |
US9474798B2 (en) | 2007-06-18 | 2016-10-25 | Wisconsin Alumni Research Foundation | Influenza M2 protein mutant viruses as live influenza attenuated vaccines |
EP2493912B1 (en) * | 2009-10-26 | 2020-07-29 | Wisconsin Alumni Research Foundation | High titer recombinant influenza viruses with enhanced replication in vero cells |
US10130697B2 (en) | 2010-03-23 | 2018-11-20 | Wisconsin Alumni Research Foundation (Warf) | Vaccines comprising mutant attenuated influenza viruses |
US20120015346A1 (en) * | 2010-07-08 | 2012-01-19 | New York Medical College | Influenza virus detection and diagnosis |
CA2875484C (en) * | 2011-06-24 | 2019-11-05 | Flugen, Inc. | Influenza virus mutants and uses therefor |
AU2013205478B9 (en) * | 2012-03-02 | 2014-11-20 | Seqirus UK Limited | Influenza virus reassortment |
JP2013099339A (ja) * | 2013-01-04 | 2013-05-23 | Wisconsin Alumni Research Foundation | H3型ウマa型インフルエンザウイルス |
WO2015009743A1 (en) * | 2013-07-15 | 2015-01-22 | Wisconsin Alumni Research Foundation | High titer recombinant influenza viruses with enhanced replication in mdck or vero cells or eggs |
KR101493613B1 (ko) * | 2013-10-25 | 2015-02-13 | 위스콘신 얼럼나이 리서어치 화운데이션 | H3 말 인플루엔자 a 바이러스 |
EP3119883A4 (en) | 2014-03-17 | 2018-01-10 | Flugen, Inc. | Influenza virus vectors and uses therefor |
WO2015196150A2 (en) | 2014-06-20 | 2015-12-23 | Wisconsin Alumni Research Foundation (Warf) | Mutations that confer genetic stability to additional genes in influenza viruses |
US10633422B2 (en) | 2015-06-01 | 2020-04-28 | Wisconsin Alumni Research Foundation (Warf) | Influenza virus replication by inhibiting microRNA lec7C binding to influenza viral cRNA and mRNA |
EP3307761A4 (en) | 2015-06-09 | 2019-01-16 | Sanofi Pasteur Inc. | PROCESS FOR OPTIMIZING NUCLEOTIDE SEQUENCES COPING MANIPULATED INFLUENZA PROTEINS |
WO2017007839A1 (en) | 2015-07-06 | 2017-01-12 | Wisconsin Alumni Research Foundation (Warf) | Improved influenza virus replication for vaccine development |
US10912864B2 (en) | 2015-07-24 | 2021-02-09 | Musculoskeletal Transplant Foundation | Acellular soft tissue-derived matrices and methods for preparing same |
JP6560056B2 (ja) * | 2015-08-07 | 2019-08-14 | ウィスコンシン アルムニ リサーチ ファンデイション | H3型ウマa型インフルエンザウイルス |
RU2660562C2 (ru) * | 2016-03-30 | 2018-07-06 | Общество с ограниченной ответственностью "ФАРМИНТЕРПРАЙСЕЗ БИОТЕХ" | Аттенуированный гриппозный вектор и мукозальная универсальная гриппозная вакцина на его основе |
CN109477074B (zh) * | 2016-02-19 | 2023-01-24 | 威斯康星旧生研究基金会 | 用于疫苗开发的改进的乙型流感病毒复制 |
JP2017038622A (ja) * | 2016-11-21 | 2017-02-23 | ウィスコンシン アルムニ リサーチ ファンデイション | H3型ウマa型インフルエンザウイルス |
WO2020167432A2 (en) | 2019-01-23 | 2020-08-20 | Yoshihiro Kawaoka | Mutations that confer genetic stability to additional genes in influenza viruses |
EP3921413A1 (en) | 2019-02-08 | 2021-12-15 | Wisconsin Alumni Research Foundation (WARF) | Humanized cell line |
WO2020223699A1 (en) | 2019-05-01 | 2020-11-05 | Wisconsin Alumni Research Foundation (Warf) | Improved influenza virus replication for vaccine development |
US11807872B2 (en) | 2019-08-27 | 2023-11-07 | Wisconsin Alumni Research Foundation (Warf) | Recombinant influenza viruses with stabilized HA for replication in eggs |
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US4071618A (en) | 1974-09-03 | 1978-01-31 | Research Foundation For Microbial Diseases Of Osaka University | Process for preparing virus disease live vaccines |
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US5166057A (en) | 1989-08-28 | 1992-11-24 | The Mount Sinai School Of Medicine Of The City University Of New York | Recombinant negative strand rna virus expression-systems |
US5854037A (en) | 1989-08-28 | 1998-12-29 | The Mount Sinai School Of Medicine Of The City University Of New York | Recombinant negative strand RNA virus expression systems and vaccines |
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ES2345643T3 (es) | 1996-07-15 | 2010-09-28 | The Government Of The Usa, As Represented By The Department Of Health And Human Services | Produccion de vacunas a base de virus respiratorio sincitial atenuado, a partir de secuencias nucleotidicas clonadas. |
EP0994949B1 (en) | 1997-05-23 | 2011-03-09 | THE UNITED STATES OF AMERICA, as represented by the Secretary of the Department of Health and Human Services | Production of attenuated parainfluenza virus vaccines from cloned nucleotide sequences |
KR100281676B1 (ko) * | 1997-11-29 | 2001-04-02 | 신동권 | 신규한독감생백신바이러스 |
US6146642A (en) | 1998-09-14 | 2000-11-14 | Mount Sinai School Of Medicine, Of The City University Of New York | Recombinant new castle disease virus RNA expression systems and vaccines |
US8715940B2 (en) | 1999-04-06 | 2014-05-06 | Wisconsin Alumni Research Foundation | Method of making recombinant influenza virus |
CN1350578B (zh) | 1999-04-06 | 2010-05-12 | 威斯康星校友研究基金会 | 用于疫苗和基因治疗的重组流感病毒 |
AU5533601A (en) | 2000-04-14 | 2001-10-30 | Wisconsin Alumni Res Found | Viruses comprising mutation ion channel protein |
PT1317559E (pt) * | 2000-04-28 | 2009-02-12 | St Jude Childrens Res Hospital | Sistema de transfecção de adn para a produção de vírus infecciosos de arn de cadeia negativa |
EP1201760A1 (en) * | 2000-10-30 | 2002-05-02 | ARTEMIS Pharmaceuticals GmbH | Influenza virus vector for human dendritic cells |
CN103540614B (zh) | 2002-02-13 | 2018-02-02 | 威斯康星旧生研究基金会 | 包装流感病毒载体的信号 |
AU2004232992A1 (en) | 2003-04-23 | 2004-11-04 | Wisconsin Alumni Research Foundation | Recombinant influenza viruses holding a mutation in a transmembrane protein gene |
WO2005028658A2 (en) | 2003-05-28 | 2005-03-31 | Wisconsin Alumni Research Foundation | Recombinant influenza vectors with a polii promoter and ribozymes |
JP5215561B2 (ja) | 2003-05-28 | 2013-06-19 | ウィスコンシン アルムニ リサーチ ファンデイション | ワクチン及び遺伝子治療のための高力価組換えインフルエンザ・ウイルス |
CA2587510A1 (en) | 2004-11-19 | 2007-04-19 | Wisconsin Alumni Research Foundation | Recombinant influenza vectors with tandem transcription units |
WO2007126810A2 (en) * | 2006-03-31 | 2007-11-08 | Warf - Wisconsin Alumni Research Foundation | High titer recombinant influenza viruses for vaccines |
-
2004
- 2004-05-27 JP JP2006533439A patent/JP5215561B2/ja not_active Expired - Fee Related
- 2004-05-27 KR KR1020057022564A patent/KR100908757B1/ko active IP Right Grant
- 2004-05-27 UA UAA200512619A patent/UA92132C2/ru unknown
- 2004-05-27 AU AU2004249133A patent/AU2004249133B2/en not_active Expired
- 2004-05-27 NZ NZ543446A patent/NZ543446A/en unknown
- 2004-05-27 EA EA200501890A patent/EA012965B1/ru not_active IP Right Cessation
- 2004-05-27 CA CA2525953A patent/CA2525953C/en not_active Expired - Lifetime
- 2004-05-27 CN CN2004800212599A patent/CN1826407B/zh not_active Expired - Lifetime
- 2004-05-27 EP EP04776133.3A patent/EP1631663B1/en not_active Expired - Lifetime
- 2004-05-27 HU HUE04776133A patent/HUE030962T2/en unknown
- 2004-05-27 BR BRPI0410702-0A patent/BRPI0410702B1/pt active IP Right Grant
- 2004-05-27 WO PCT/US2004/016680 patent/WO2004112831A2/en active Application Filing
- 2004-05-27 US US10/855,875 patent/US8475806B2/en not_active Expired - Lifetime
- 2004-05-27 MX MX2012009249A patent/MX342639B/es unknown
- 2004-05-27 ES ES04776133.3T patent/ES2593082T3/es not_active Expired - Lifetime
-
2005
- 2005-11-08 IL IL171831A patent/IL171831A/en active IP Right Grant
- 2005-12-19 ZA ZA200510309A patent/ZA200510309B/en unknown
- 2005-12-20 NO NO20056074A patent/NO341506B1/no unknown
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2006
- 2006-04-28 HK HK06105116.2A patent/HK1082769A1/zh unknown
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2012
- 2012-12-14 JP JP2012273898A patent/JP5695020B2/ja not_active Expired - Lifetime
-
2015
- 2015-05-03 IL IL238584A patent/IL238584B/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
JP5215561B2 (ja) | 2013-06-19 |
CN1826407B (zh) | 2013-09-11 |
JP2007518395A (ja) | 2007-07-12 |
BRPI0410702B1 (pt) | 2022-04-12 |
EP1631663A2 (en) | 2006-03-08 |
WO2004112831A3 (en) | 2005-03-24 |
IL238584B (en) | 2020-06-30 |
NO20056074L (no) | 2006-03-22 |
US20050003349A1 (en) | 2005-01-06 |
AU2004249133A1 (en) | 2004-12-29 |
JP2013059346A (ja) | 2013-04-04 |
JP5695020B2 (ja) | 2015-04-01 |
US8475806B2 (en) | 2013-07-02 |
IL238584A0 (en) | 2015-06-30 |
EA012965B1 (ru) | 2010-02-26 |
AU2004249133B2 (en) | 2009-05-28 |
ES2593082T3 (es) | 2016-12-05 |
NZ543446A (en) | 2008-06-30 |
KR100908757B1 (ko) | 2009-07-22 |
CA2525953C (en) | 2023-10-10 |
EP1631663B1 (en) | 2016-08-24 |
CA2525953A1 (en) | 2004-12-29 |
MX342639B (es) | 2016-10-07 |
KR20060016095A (ko) | 2006-02-21 |
CN1826407A (zh) | 2006-08-30 |
HUE030962T2 (en) | 2017-06-28 |
HK1082769A1 (zh) | 2006-06-16 |
NO341506B1 (no) | 2017-11-27 |
WO2004112831A2 (en) | 2004-12-29 |
BRPI0410702A (pt) | 2006-06-13 |
ZA200510309B (en) | 2006-08-30 |
IL171831A (en) | 2015-05-31 |
UA92132C2 (ru) | 2010-10-11 |
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